DRUGS NAME Mechanisms of Indications Contraindications Adverse Effects Nursing Responsibilities

Action
1. Amikacin IV Inhibits production of Treatment of A history of This medication may  Patients should be
bacterial protein, infections caused by hypersensitivity to cause nausea, vomiting counseled that
causing bacterial cell susceptible strains of Amikacin is a or weakness as your antibacterial drugs
death. microorganisms, contraindication for its body adjusts to the including Amikacin
especially gram- use. A history of medication. If these should only be
negative bacteria. hypersensitivity or serious effects continue or used to treat
toxic reactions to become severe, inform bacterial
aminoglycosides may your doctor. This infections.
contraindicate the use of medication can cause
any other aminoglycoside hearing loss or kidney  Patients should be
because of the known damage especially if told that although
cross-sensitivities of used in high doses or it is common to
patients to drugs in this for prolonged periods of feel better early in
class. time. It is important the the course of
proper dose be used. therapy, the
The site where the medication should
injection is given may be taken exactly
be red and irritated for as directed.
a few days. Notify your
doctor if the irritation  Skipping doses or
continues or becomes not completing
worse. Notify your the full course of
doctor immediately if therapy may (1)
you develop: dizziness, decrease the
ringing in the ears, effectiveness of
hearing loss, skin rash, the immediate
difficulty breathing, treatment and (2)
difficult or painful increase the
urination, muscle likelihood that
twitching. If you notice bacteria will
other effects not listed develop resistance
above, contact your and will not be
doctor or pharmacist. treatable by
2. Penicillin- G Amikacin or other
Benzathine antibacterial drugs
Inhibits cell wall Moderate to severe Contraindicated to patient in the future.
synthesis during systemic infections hypersensitive to drug.
bacterial multiplication

This medication may

cause mild diarrhea,
stomach upset, nausea,  Before giving
vomiting or irritation at drug, ask patient,
injection site during the about allergic
first few days as your reaction to drugs.
body adjusts to the
medication. If these  Tell patient to
symptoms persist or report adverse
worsen, inform your reaction to drugs.
doctor. Notify your
doctor immediately if  Assess medical
you develop: watery history, especially
diarrhea, stomach of: kidney
cramps, fever, unusual disease,
bleeding or bruising, stomach/intestinal
yellowing of the eyes or diseases, allergies
skin, unusual tiredness (especially
or weakness. In the allergies to
unlikely event you have penicillins, other
an allergic reaction to antibiotics,
this drug, seek medical procainamide,
attention immediately. ester-type
Symptoms of an allergic anesthetics such
reaction include: as lidocaine, PABA
wheezing, difficulty products such as
breathing, skin rash. methylparaben