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(Acquired
Immunodeficiency
Syndrome)
AIDS
(Acquired Immunodeficiency Syndrome)
The first case of AIDS in the Philippines was reported in 1984. As of
May 2000 based on the Philippine National AIDS council
record, there were 1,385 HIV positive and AIDS cases, 206
deaths.
Causative agent:
HIV (Human Immunodeficiency Virus)
Mode of Transmission:
Sexual contact, Transfer of body fluids (blood, semen,
discharges), contaminated syringe, transplacental
Signs and Symptoms:
Physical Mental
1. Rashes 1. Forget fullness
2. Loss of appetite 2. Loss of concentration
3. Weight loss 3. Loss of libido
4. Fever of unknown origin 4. Psychomotor- retardation
5. Pneumocystis carinii 5. Confusion
pneumonia (Pneumocystis 6. Disorientation
jiroveci)
7. Seizures
6. Persistent diarrhea
8. Mutism
7. Esophageal candidiasis
9. Loss of memory
8. Kaposis Darcoma (skin
cancer) 10. Coma
Treatment:
Azidothymidine (AZT) and Didanosine
inhibit HIV replication by inhibiting
reverse transcriptase. Clinical
improvement occurs but the virus
persists. Treatment of opportunistic
infection depends on the organism
Prevention:
Screening of blood prior to transfusion,
safe sex. There is no vaccine
GONORRHEA
Causative agent:
Neisseria gonorrheae
Mode of transmission:
Sexual contact in adult, transmission in neonates is
during birth
It tends to infect warm, moist areas of the body, including
the:
urethra (the tube that drains urine from the urinary bladder)
eyes
throat
Vagina
Anus
Signs and Symptoms:
Genital (penis or cervix), anus, throat and
eyes can be infected
Causative agent:
Treponema pallidum
Prevention:
Same as other bacterial STI.
No vaccine available.
Benzathine penicillin s given to contacts.
Chlamydia
Causative agent:
Chlamydia trachomatis
Mode of Transmission:
Through sexual contact and birth
Signs and Symptoms:
In males- discharge from penis, burning and
itching of the urethral opening, burning sensation
during urination
In females- slight vaginal discharge, itching and
burning sensation of vagina, painful intercourse,
abdominal pain.
Treatment:
Tetracycline and Erythromycin
Prevention:
No vaccine available. Erythromycin is effective in
infected mother to prevent neonatal disease.
Trichomoniasis
Causative agent:
Trichomonas vaginalis
Mode of transmission:
Usually passed by direct sexual
contact. Can be transmitted through
contact with wet objects such as
towels, wash clothes, etc.
Treatment:
Azidothymidine (AZT) and Didanosine
inhibit HIV replication by inhibiting
reverse transcriptase. Clinical
improvement occurs but the virus
persists. Treatment of opportunistic
infection depends on the organism
Prevention:
Screening of blood prior to transfusion,
safe sex. There is no vaccine
Genital herpes
Causative agent:
Herpes simplex Virus type 2 (HSV2)
Mode of transmission:
Sexual contact in adult and during
passage through the birth canal in
neonates
Signs and Symptoms:
Painful vesicular lesion of the male and
female genitals and anal area.
Treatment:
Acyclovir is useful in the treatment of both
primary and recurrent diseases.
Prevention:
Primary disease can be prevented by
protection from exposure to vesicular
lesion. There is no vaccine.
Hepatitis B
Causative agent:
Hepatitis B Virus (HBV)
Mode of Transmission:
Sexual intercourse, also transmitted
through blood and during birth
Signs and Symptoms:
a. Loss of appetite
b. Easy fatigability
c. Joint and muscle pain
d. Low grade fever
e. Right sided abdominal pain
f. Jaundice
g. Dark colored urine
Treatment:
No specific treatment
Prevention:
a. Vaccine that contain HBsAg as the
immunogen
b. Hyper immune serum globin
obtained from donors with high titers
of HBsAb