Vascular Family Hx insulin resistance, make Gliclazide, diamicron, Family Hx muscle Old Age islet cells in pancreas wear hypoglycemics Old Age defects out quickly Race (Asian) Hardening of vascular Increased Vascular cell walls and wall thickness and reduced elasticity Decreased insulin use Decreased insulin levels reactivity leading to smaller, obstructed vessels Increased blood flow Increased Diabetic Kidney Disease Kidney Failure Peripheral resistance
High glucose levels + low insulin use
Chronic high blood (possible high insulin levels as well due to Candesartan, pressure leads to damage insulin overproduction from beta cells) levamlodipine, of weaker/smaller vessels asomex, rosufen
Decreased glucose: Unknown mechanism
wherein high blood sugar Increased Janumet, insulin, damages filtration system in Increased Peripheral empagliflozin, kidneys, resulting in failure blood flow resistance pioglitazone, metformin Atherosclerosis; plaque build up Increased glucose levels High plasma and ECF volume Decreased glucose use Fatty food intake Diet Diet Sedentary Lifestyle High salt and Sedentary Lifestyle water retention High salt intake