SEMI-DETAILED LESSON PLAN ON GENETIC ENGINEERING

October 23, 2017

I. OBJECTIVES
A. Content Standard The learners demonstrate an understanding
of how genetic engineering is used to
produce novel products.
B. Performance Standard
The learners shall be able to conduct a
survey of products containing substances
that can trigger genetic disorders such as
phenylketonuria.

The learners describe the process of

C. Learning Competency
genetic engineering.
The learners enumerate advantages
and disadvantages of genetic
engineering.
The learners value the pros and
cons of genetic engineering.

Code: S11/12LT-IIej-17
II. CONTENT
A. Subject Matter Perpetuation of Life
Subtopic: Genetic Engineering
III. LEARNING RESOURCE
A. Page in Curriculum Guide Pages 6 and 7
B. Reference Book: Biology by Addison-Wesley, pages 188-199

C. Other sources Internet

IV. PROCEDURE
A. ELICIT
Show the students a video presentation of Gregor Mendels work about the
foundations of heredity and the concept of how genes work. After the video,
let the students identify the common terms in genetics through a Who am
I? game.

1. I am the father of Heredity. Who am I?

2. I am a gene that can be masked by a dominant gene. Who am I?
3. I am the observable properties of an organism that are produced by the
interaction of the sets of genes and the environment. Who am I?
4. I am an alternative form or a varied form of a gene. Who am I?
5. I am a unit of heredity that is transferred from a parent to offspring and is
held to determine some characteristic of the offspring. Who am I?

B. ENGAGE
The students will play a guessing game of different anime characters.
At the latter part of the guessing game would showcase the idea of fusion
of two entities.

C. EXPLORE
Unlocking of Difficulties
Familiarize the students of the possible terminologies to be used in
discussing the process of genetic engineering. Those words are listed below.

1. VECTOR- any carrier that transfers genetic information into a cell.

2. PLASMIDS- are small circular pieces of DNA within a bacterium.
3. ALTERATION- an act of changing something that is natural.
4. TRANSGENE- a gene that is taken from the genome of one
organism and introduced into the genome of another organism by
artificial techniques.
 5. TRANSGENIC- it denotes an organism that contains genetic
material into which DNA from other organism has been artificially
introduced.

D. EXPLORE
Show the video THE SCARECROW to the learners and allow them to
describe whatever is the content of the video.

E. EXPLAIN
GENETIC ENGINEERING DEFINED

Genetic Engineering- refers to the direct manipulation of DNA to alter an

organisms characteristics in a particular and desired way. It is also called as
genetic modification or the alteration of the DNA in an organisms genome.

GOAL OF GENETIC ENGINEERING

The aim of the study, development and practice of genetic engineering is to
raise the standard of living of mankind by producing organism having
desirable traits.

THE PROCESS OF GENETIC ENGINEERING

1. DNA EXTRACTION- Isolation of DNA fragments from a donor organism.
2. GENE CLONING- Isolation of the desired gene from the set of genes.
3. GENE INSERTION- Insertion of an isolated donor DNA fragment into a
vector genome.
4. TRANSGENESIS- Transgenes from vectors are now inserted to target
organisms to be modified. Transgenesis is the process of introducing
an exogenous genecalled a transgeneinto a living organism so that
the organism will exhibit a new property and transmit that property to
its offspring. Transgenesis can be facilitated
by liposomes, enzymes, plasmid vectors, viral vectors, pronuclear
injection, protoplast fusion, and ballistic DNA injection.
5. PROPAGATION OF TRANSGENIC ORGANISM- the transgenic
organisms are propagated through cloning or breeding.

F. EXPLAIN
Deepen the lesson by giving the types of genetic engineering.
1. Somatic Engineering- targets specific genes of the body in specific
organs and tissues, and it does not affect the genes in the eggs or sperm.
This type of genetic engineering treats or cures existing conditions, but it
does not alter an individuals entire genetic makeup.
(shows examples of Somatic GMOs).

2. Germline engineering- targets the genes in eggs, sperm or embryos

during very early stages of their development. All the cells in embryos are
genetically affected. Future generations can inherit the changes in
germline engineering.
(shows examples of Germline GMOs.)

3. Cloning- process of creating identical copies of an organism.

(shows cloned organisms).

G. ELABORATE
G.1
1. The learners will enumerate advantages of genetic engineering.
2. The learners will enumerate disadvantages of genetic engineering.

G.2
The teacher will ask for the pulse of the class regarding the pros and cons of
genetic engineering through a survey game- PULSE SCIENTIA

H. ELABORATE
Using a mind map, five to 10 (5-10) representative learners will give related
words on GENETIC ENGINEERING, they will first state the terms and give
 their learning related to the terms chosen and then write the term in the
graphic organizer to make a mind map that will summarize the lesson.
(The teacher will clear misconceptions, if there is.)

I. EVALUATE
Using a flowchart, the students will make a graphic organizer picturing the
process of genetic engineering. The graphic organizer will be assessed using
a rubric. (Please see attached sheet for the rubric).

J. EXTEND
(To be written in a letter size paper).

1. How would you feel about eating foods from plants or animals that have
been genetically altered? Why do you feel this way?

V. REMARKS
VI. REFLECTIONS

Prepared by:

HARLENE T. BUENDIA
Demonstration Teacher, Division of Nueva Ecija

Checked and Reviewed by:

RICARDO A. DE GUZMAN
Facilitator, Education Program Specialist II, Division of Bulacan

Approved by:

LIBRADA RUBIO
Education Supervisor II
 Republic of the Philippines
DEPARTMENT OF EDUCATION
Region III

A Semi-Detailed Lesson Plan in the Process of

Genetic Engineering demonstrated to the
Regional Mass Training of Senior High School
Teachers

(Subic Bay Travelers Hotel, Olongapo City)

October 23, 2017