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Objectives
The purposes of this module are to: Infection alters the metabolism of energy, carbohydrates,
1. Describe the risk factors that contribute to fats, proteins, vitamins, and minerals, increasing the
malnutrition in HIV/AIDS. bodys need for these nutrients.
2. Explain how to conduct a nutritional assessment
Fever increases calorie needs by 12 percent for each
of children and adults.
degree Centigrade above normal and 7 percent for
3. Explain how to determine nutrient needs of
each degree Fahrenheit above normal. Fever may also
children and adults.
increase protein utilization. Sepsis (a generalized
4. Describe nutrition intervention strategies for
infection) increases calorie needs by 60 percent.
problems associated with HIV/AIDS.
5. Emphasize the importance of preventing Gastrointestinal (GI) manifestations of HIV/AIDS
foodborne illness. include diarrhea and malabsorption; oral, esophageal,
and gastric illnesses; and nausea and vomiting.
Key Points Diarrhea and malabsorption (not always found
together) can lead to vitamin, mineral, protein, fat,
1. HIV infection can frequently result in nutritional
and carbohydrate losses as well as a decrease in oral
deficiencies and growth failure.
intake. Diarrhea increases calorie needs by 25 percent.
2. Malnutrition associated with HIV/AIDS can
Malabsorption may occur without diarrhea because
severely affect an already compromised immune
of metabolic changes associated with the disease,
system, leading to increases in rates of opportunistic
which lead to loss of nutrients.
infections and a decreased survival rate.
3. It is important to monitor and maintain Severe oral candidiasis (yeast) and herpes
adequate nutritional status in HIV-infected gingivostomatitis, viral esophagitis, and gastritis can
children and adults. make eating difficult and painful, leading to decreased
oral intake or feeding refusal. Nausea and vomiting
Causes of Malnutrition caused by drugs, infection, and/or illness can lead to
poor oral intake as well as loss of nutrients.
Factors that contribute to malnutrition in people with
HIV or AIDS include infection, fever, gastrointestinal Feeding and eating problems can occur with HIV/
illnesses, developmental problems, and economic and AIDS. Infants with HIV can have a weak suck,
psychosocial issues. leading to inadequate intake of breast milk or formula.
Older children can have poor chewing and feeding
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skills. Difficulty swallowing can lead to poor oral To assess growth, the health care provider should plot
intake or complete refusal to eat. There is a risk of the patients weight and height/length on a growth
aspiration and pneumonia with swallowing problems. chart. Any prior weights and lengths that are available,
Children or adults with HIV/AIDS can lose feeding including birth weight, are helpful to plot trends in
skills due to neurological deterioration, leading to the patients growth. The World Health Organization
inadequate intake of nutrients. (WHO) recommends using the U.S. National Center
for Health Statistics (NCHS) growth charts. The most
Economic issues that can lead to inadequate nutrient
recently updated set of growth charts is available at
intake include a limited food supply, loss of household
the end of this chapter and at the U.S. Centers for
income or livelihood (such as farming) due to illness,
Disease Control and Prevention Web site on the
as well as limited cooking and storage facilities. Also,
Internet: http://www.cdc.gov/growthcharts/. The
parents may be too ill or uninterested to care for
growth charts include body mass index (BMI) charts
themselves and their children. Depression in an adult
for up to 20 years of age for males and females.
or child can also lead to poor nutrient intake.
Growth failure is defined as:
Nutrition Assessment 1. Crossing two major percentile lines on the NCHS
growth charts over time. The charts show the
Once malnutrition risk factors are identified, a
97th, 95th, 75th, 50th, 25th, 10th, 5th, and 3rd
nutrition assessment can be done. An assessment
percentile lines. If, for example, a patients weight
includes examining weight gain and linear growth,
or length falls from the 25th to below the 5th
growth failure, nutrition laboratory values if available,
percentile, the patient has crossed two percentile
and diet and feeding history.
lines on the growth chart.
For children, weight gain and linear growth are 2. For a child whose weight is below the 5th
important components
of a nutrition assessment.
The weight of the
pediatric patient in
kilograms (kg) and the
length or height in
centimeters (cm) are
valuable assessment tools.
For children up to age 3,
measurement of the
frontal occipital (head)
circumference (FOC) in
centimeters is also a
valuable tool to assess
growth. Weight alone is
adequate to assess growth
when no other
measurements are
available.
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percentile for age: failing to follow along a normal Degree of Malnutrition Percent of Ideal Weight
upward growth curve on the growth chart. If 1st 75-85
there is no weight gain or inadequate weight 2nd 64-74
gain, there is no indication of growth along a 3rd <64
normal curve the line on the growth chart
To assess the nutritional status of an adult, a formula
would be flat or drop.
for determining ideal body weight is:
3. Loss of 5 percent or more of body weight.
Male: 48 kg + 1.07 kg/cm if height is over 152 cm
Acute and chronic degrees of malnutrition for children
Female: 45.5 kg + .9 kg/cm if height is over 152 cm
are assessed using the Waterlow Criteria, as follows:
For an adult, malnutrition can be defined as
Acute malnutrition =
involuntary weight loss greater than 10 percent or
actual w eight weight less than 90 percent of ideal weight.
x 100
50th per centile w e i g h t / l e n g t h
on NCHS char t Laboratory values that are helpful when doing a
nutrition assessment, in both the pediatric and adult
Stage 0 (normal): >90 percent populations, are the complete blood count (CBC),
Stage I (mild): 81-90 percent total protein, albumin (dehydration can lead to falsely
Stage II (moderate): 70-80 percent elevated serum levels), and prealbumin (which has a
Stage III (severe): <70 percent half life of several days, versus about two weeks for
albumin). Albumin and prealbumin assess visceral
Chronic malnutrition = protein status (muscle mass).
actual length/height Dietary intake and feeding history are important
x 100
50th per centile height/age on aspects of a nutrition assessment. The adequacy of
NCHS char t nutrient intake can be assessed based on a 24-hour
Stage 0 (normal): >95 percent patient diet recall (a list of what the patient normally
Stage I (mild): 90-95 percent eats and/or ate in the past 24 hours) or a three-day
Stage II (moderate): 85-89 percent food intake record (kept in writing by the patient or
Stage III (severe): <85 percent a caretaker). It is important to interview the
patient/caretaker to find out the types and estimated
When length/height measurements are not available, amounts of foods/formula/fluids/breast milk consumed.
the Gomez Criteria can be used to determine degree Other important information includes the length of
of malnutrition, but these fail to assess the proportion time it takes the patient to eat; the patients appetite;
of weight to height. The Gomez Criteria are used as any chewing, sucking, or swallowing problems; any
follows: nausea, vomiting, diarrhea, and abdominal pain; and
any feeding refusal, food intolerance, allergies, and
Determine the weight for age at the 50th percentile
fatigue. If the patient is a child, who feeds the child
on the NCHS growth chart (ideal weight).
and provides the food for the child should be known.
Percent of ideal body weight=
actual w eight
x 100 Determining Nutrient Needs
ideal w eight
of Children and Adults
Determine the degree of malnutrition:
Reversing weight loss, malnutrition, and wasting can
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help boost the immune system of a child or adult who for at least 12 hours, can be calculated using the
is HIV-positive. An easy approach to determining Harris Benedict formula:
increased calorie needs of an HIV-positive child or
For women:
adult is to use the U.S. Recommended Dietary
655.1
Allowance (RDA) general population energy
+(9.6 x w e i g h t i n k g )
guidelines (see tables 1, 2, and 3) and increase the
+ (1.7 x height in cm)
number of calories (kcals/day) to at least 150 percent
(4.7 x age in y e a r s )
of recommended energy levels.
For men:
To determine more exact calorie needs of an HIV-
66.5
positive child, a few things need to be considered. Is
+ (13.8 x w eight in kg)
the child ill? Has she lost weight, and has her linear
+ (5 x height in cm)
growth been affected? Does she exhibit malnutrition
(6.8 x age in y e a r s )
based on the Waterlow or Gomez criteria? Is she
severely wasted? A method to determine calorie needs Once the BEE is calculated, activity factors and
for a child who has not been gaining weight or growing injury factors need to be determined. These are
is to assess the childs energy needs for catch-up growth. multiplied with the BEE to estimate calorie needs.
Catch-up growth means weight gain and growth to
catch up to within normal limits for the childs age. BEE x (activity factor) x (injur y factor) =
The formula to determine energy needs for catch-up estimated calor ie needs
growth is: Activity Factors Injur y Factors
Bed rest 1.2 Minor surgery 1.2
ideal body w eight (kg) x RDA kcals/kg for age
Ambulatory 1.3 Skeletal trauma 1.35
curr e n t w e i g h t ( k g )
Major sepsis 1.6
Severe burns 2.1
These are starting points and need to be adjusted if
there is fever, sepsis, lack of weight gain/growth, or If a child or adult is bed-ridden, the resting energy
continued weight loss. expenditure (REE) in tables 1, 2, and 3 can be used to
determine calorie needs. The REE, based on a body at
For HIV-positive adults, increased calorie needs can
rest after a meal, will vary from patient to patient
be determined more precisely using kcals/day in
depending on factors such as fever and infections.
Table 3 or the basal energy expenditure (BEE), along
with activity and injury factors. The BEE, a measure HIV/AIDS also increases losses of protein. To
of energy expenditure in a body at rest after fasting determine protein requirements of children, the same
Table 1: Estimated Energy and Protein Requirements for Infants and Children
Reference REE RDA Energy Protein
Category Age (years)
Weight (kg) (kcal/kg) Energy (kcal/kg) (kcal/day) (gram/kg)
Infants 0.0-0.5 6 55 108 650 2.2
0.5-1.0 9 55 98 850 1.6
Children 1-3 13 55 102 1300 1.2
4-6 20 45 90 1800 1.1
7-10 28 40 70 2000 1.0
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formula as for catch-up growth can be used, For adults with HIV, starting at 2-2.5 g/kg/day of
substituting RDA protein for calories (see tables 1 protein is recommended.
and 2):
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Foods high in protein help maintain muscle mass. foods. They can be used in addition to a healthy diet
Sources of protein include meat (beef, mutton, pork), to provide extra calories.
organ meats, fish, chicken, eggs, milk, dairy products
Patients with HIV/AIDS often lack vitamins and
such as yogurt and cheese, and mopari worms and
minerals because of inadequate dietary intake,
other insects. Inexpensive sources of protein include
infection, and malabsorption. Vitamins A, C, E, and
legumes such as beans and peas, nuts, peanut butter,
B are important for immune function. Vitamins A
and seeds, as well as grains such as rice, maize, barley,
and C are important for wound healing, and vitamin
oats, wheat, rye, sorghum, millet, and corn. Grains
A for vision. The B vitamins are also important for
and legumes need to be combined with each other or
energy production, red blood cell production, and
eaten in the same day or eaten with another protein
growth. Vitamin E is important in red blood cell
source such as meat. If these foods are not combined
production. Minerals such as zinc and selenium are
or eaten on the same day, the protein they provide is
important in immune function and, along with other
considered incomplete. Vegetables and fruits are
minerals such as iron, magnesium, potassium,
important sources of essential vitamins and minerals,
phosphorus, and copper, are often depleted in
especially vitamins A and C, and need to be eaten daily.
association with HIV infection. Because vitamins and
Table 4 provides a list of important vitamins and
minerals play such an important role in the body, a
minerals and their sources.
daily multiple vitamin/mineral supplement is of
Fats and oils are also an important part of the diet, benefit to HIV-positive patients, whether they are
providing calories and essential vitamins and fatty symptomatic or asymptomatic. If a vitamin is not
acids. Sources of fat include butter, margarine, feasible, it is especially critical to promote a healthy
cooking oils, cream, mayonnaise, and salad dressings. diet with a variety of foods.
Sugar, sweets, and desserts are good sources of calories Table 5 shows a list of clinical signs of vitamin and
but should not be used in place of more nutritious mineral deficiencies.
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Review Questions
1. Review the specific factors that contribute to 4. How do you assess nutritional status based
malnutrition in people with HIV/AIDS. on a persons weight and height?
2. What are the increased energy requirements 5. How do you calculate the nutritional needs
associated with illness in people with of child and adolescents with HIV/AIDS?
HIV/AIDS?
6. What are the appropriate nutritional
3. What are the essential components of a interventions to support increased energy
nutritional assessment for children and adults and/or protein needs for a person with
with HIV/AIDS? HIV/AIDS?
Exam Questions
1. All of the following are factors contributing b. Increase fats and starches in the diet
to malnutrition in HIV/AIDS except: c. Increase intake of fruits and vegetables
a. Increased energy requirements d. Increase intake of water
b. Infection
c. Developmental problems 4. In order to meet protein needs for children
d. Exercise with HIV/AIDS, how much can the daily
protein intake be increased?
2. Which measure of growth is essential for a. Not to exceed 2 gm/kg/day
evaluation of children? b. Not to exceed 6 gm/kg/day
a. Frontal occipital circumference for c. Not to exceed 4 gm/kg/day
children older than 5 years d. Not to exceed 1 gm/kg/day
b. Height plotted on a growth chart
c. Frontal occipital circumference for 5. Growth failure in children is defined as:
children up to 3 years old a. Crossing three major percentile lines of
d. Weight compared to ideal body weight the NCHS growth charts over time
b. Failure to follow growth curve on a
3. Effective methods to increase calories when growth chart
illness is present include: c. Loss of 1 percent or more of body
a. 250 percent increase in recommended weight
calories d. Chronic diarrhea and vomiting
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Case Studies
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Wt: 3.2 kg is <3rd percentile for age Question: What are C.F.s current calorie and
Length: 52 cm is <3rd percentile for age protein needs?
Wt/length is at the 3rd percentile
Answer: 3.7 kg x 108 kcal/kg / 3.2 kg
FOC: 25th percentile (was at the 50th percentile
= 125 kcal/kg/day
at birth)
+ calorie needs for diarrhea (25 percent, or
IBW: 3.7 kg; actual wt is 86 percent of IBW
31.2 calories)
Ideal ht for age: 61 cm; actual ht is 85 percent of
= 156 kcal/kg/day
ideal ht
3.7 x 2.2 g pro/kg / 3.2 = 2.5 x 25 percent
Question: Is there any evidence of malnutrition?
= 3.1 g pro/kg/day
(See the Waterlow Criteria.)
Regular weight and length checks are important to
Answer: Yes, this infant has Stage I (mild) acute
determine whether the nutrition intervention is
malnutrition and Stage II (moderate) chronic
working. If nasogastric feeds are necessary for more
malnutrition.
than eight weeks, a gastrostomy may need to be
Next steps: considered.
Find out what the baby is eating breast milk or
formula? Case Study
If the baby is breastfeeding, find out how long
A 30-year-old man comes to the clinic complaining
she takes at a feeding, whether the mother is
of a cough of three weeks duration with fatigue and
introducing other foods/fluids; and whether the
weight loss. His partner was recently diagnosed as HIV-
mother is malnourished and not producing
positive, and this patient does not know his HIV
enough milk.
status. He has had little appetite and complains of
If the baby is on formula, what type and how
pain when he swallows. His weight is 55 kg, and his
much does she drink at a feeding? How long does
height is 178 cm. He is found to have tuberculosis
she take to drink a bottle?
and candidiasis, and testing shows he is HIV-
Does the baby get tired easily while feeding?
positive.
Does the baby cry and arch her back with
feedings? (Possible gastroesophageal reflux?) Question: What is an appropriate weight
How long has the baby had diarrhea? Is the for this man?
infant getting enough fluids?
Answer: Approximately 75 kg (see Page 259 for
The baby will need to be tested for pathogens in the calculation)
stool. If pathogens are the cause of her diarrhea and
she is treated, the infant can probably be kept on her Question: What are his current calorie needs?
current type of feeding, but volume and possibly Answer: His BEE is calculated to be 2283
calorie concentration will need to be increased. If calories, and his activity factor is ambulatory (1.3).
pathogens are not present, the baby may need to be His stress factor is equivalent to sepsis (1.6),
put on an elemental formula, if available, to aid considering his HIV status and tuberculosis. Based
absorption and decrease diarrhea. If the baby is on this, the man would need 2283 x 1.3 x 1.6 = 4750
unable to eat enough by mouth, a nasogastric tube calories per day. This is only an estimate. It may be
may need to be placed to provide enough calories helpful to do a diet recall and assess his current food
and fluids for the child. Formula can be concentrated intake to determine what he needs to add to his diet
and have additives to increase calories and protein.
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to gain weight and to receive an adequate amount of Question: Are there any other nutritional
both macro and micronutrients. recommendations that can be made?
Question: Will the candidiasis affect his food Answer: Yes, this patient, and all patients who are
intake? HIV-positive, would benefit from a multiple
vitamin/mineral supplement to at least twice the U.S.
Answer: Yes, this could be why he has pain with
RDA. Also, if the patient has fever, his calorie needs
swallowing, as the candidiasis may be affecting his could be even higher than estimated above. It is
esophagus. Soft non-spicy, and cold foods may help important to have follow-up visits to assess his
reduce the pain. Also, cold liquids that are not acidic nutritional status.
are recommended.
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