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Circulation

JOURNAL OF THE AMERICAN HEART ASSOCIATION


Volume 114 Number 16
October 17, 2006

European Perspectives . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . f161f164


Issue Highlights 1669

Editorials
Transvenous Radiofrequency Catheter Ablation for Atrial Flutter and Atrial Fibrillation: The End of the
Beginning?
D. George Wyse, MD, PhD 1670
Cardiac Troponin: Friend of the Cardiac Physician, Foe to the Cardiac Patient?
Alan H.B. Wu, PhD 1673
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Original Articles
Arrhythmia/Electrophysiology
Results From the Loire-Ardche-Drme-Isre-Puy-de-Dme (LADIP) Trial on Atrial Flutter, a Multicentric
Prospective Randomized Study Comparing Amiodarone and Radiofrequency Ablation After the First
Episode of Symptomatic Atrial Flutter
Antoine Da Costa, MD, PhD; Jrme Thvenin, MD; Frdric Roche, MD, PhD;
Ccile Romeyer-Bouchard, MD; Loucif Abdellaoui, MD; Marc Messier, PhD; Lucien Denis, MD;
Emmanuel Faure, MD; Rgis Gonthier, MD; Georges Kruszynski, MD; J. Marie Pages, MD;
Serge Bonijoly, MD; Dominique Lamaison, MD; Pascal Defaye, MD; J. Claude Barthlemy, MD, PhD;
Thierry Gouttard, MD; Karl Isaaz, MD, FESC; for the Loire-Ardche-Drme-Isre-Puy-de-Dme (LADIP) Trial
of Atrial Flutter Investigators Clinical Perspective CME 1676
Gene Transfer of a Synthetic Pacemaker Channel Into the Heart: A Novel Strategy for Biological Pacing
Yuji Kashiwakura, MD, PhD; Hee Cheol Cho, PhD; Andreas S. Barth, MD; Ezana Azene, PhD;
Eduardo Marbn, MD, PhD Clinical Perspective 1682

Epidemiology
Low Birth Weight, a Risk Factor for Cardiovascular Diseases in Later Life, Is Already Associated With
Elevated Fetal Glycosylated Hemoglobin at Birth
Thiemo Pfab, MD; Torsten Slowinski, MD; Michael Godes, MD; Horst Halle, MD, PhD; Friedrich Priem;
Berthold Hocher, MD, PhD Clinical Perspective 1687

Heart Failure
Cardiac Troponin I but Not Cardiac Troponin T Induces Severe Autoimmune Inflammation in the
Myocardium
Stefan Gser; Martin Andrassy, MD; Sebastian J. Buss, MD; Florian Leuschner, MD; Christian H. Volz, MD;
Renate ttl; Stefan Zittrich; Natascha Blaudeck, PhD; Stefan E. Hardt, MD; Gabriele Pfitzer, MD;
Noel R. Rose, MD, PhD; Hugo A. Katus, MD; Ziya Kaya, MD Clinical Perspective 1693
Pirfenidone Prevents the Development of a Vulnerable Substrate for Atrial Fibrillation in a Canine Model
of Heart Failure
Ken W. Lee, MD, MS; Thomas H. Everett IV, PhD; Dulkon Rahmutula, MD, PhD; Jose M. Guerra, MD;
Emily Wilson, BS; Chunhua Ding, MD, PhD; Jeffrey E. Olgin, MD Clinical Perspective 1703

CIRCULATION (ISSN 0009-7322) is published weekly except combined the first two weeks in January and the last two weeks in December by Lippincott Williams & Wilkins at 16522
Hunters Green Parkway, Hagerstown, MD 21740. Business offices are located at 530 Walnut Street, Philadelphia, PA 19106-3621. Production offices are located at 351 West Camden
Street, Baltimore, MD 21201-2436. Individuals may subscribe for their personal use at the following rates: $216 for members of an American Heart Association scientific council and
$339 for nonmembers; international: $371 for members of an American Heart Association scientific council and $579 for nonmembers. Periodicals postage paid at Hagerstown, MD,
and additional mailing offices. POSTMASTER: Send address changes to CIRCULATION, American Heart Association, Lippincott Williams & Wilkins, 16522 Hunters Green Parkway,
Hagerstown, MD 21740.
Molecular Cardiology
Midkine Plays a Protective Role Against Cardiac Ischemia/Reperfusion Injury Through a Reduction of
Apoptotic Reaction
Mitsuru Horiba, MD; Kenji Kadomatsu, MD; Kenji Yasui, MD; Jong-Kook Lee, MD; Hiroharu Takenaka, MD;
Arihiro Sumida, MD; Kaichiro Kamiya, MD; Sen Chen, MD; Sadatoshi Sakuma, PhD;
Takashi Muramatsu, PhD; Itsuo Kodama, MD Clinical Perspective 1713
Absence of Malonyl Coenzyme A Decarboxylase in Mice Increases Cardiac Glucose Oxidation and Protects
the Heart From Ischemic Injury
Jason R.B. Dyck, PhD; Teresa A. Hopkins, PhD; Sebastien Bonnet, PhD; Evangelos D. Michelakis, MD;
Martin E. Young, PhD; Miho Watanabe, PhD; Yosuke Kawase, PhD; Kou-ichi Jishage, PhD;
Gary D. Lopaschuk, PhD Clinical Perspective 1721

Vascular Medicine
Potent Reduction of Apolipoprotein B and Low-Density Lipoprotein Cholesterol by Short-Term
Administration of an Antisense Inhibitor of Apolipoprotein B
John J.P. Kastelein, MD, PhD; Mark K. Wedel, MD, JD; Brenda F. Baker, PhD; John Su, PhD;
JoAnn D. Bradley, PhD; Rosie Z. Yu, PhD; Emil Chuang, MD; Mark J. Graham, BS;
Rosanne M. Crooke, PhD Clinical Perspective 1729
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Controversies in Cardiovascular Medicine


Are Drug-Eluting Stents Cost-Effective? It Depends on Whom You Ask
Jason Ryan, MD, MPH; David J. Cohen, MD, MSc 1736
Drug-Eluting Stents: The Price Is Not Right
Mark J. Eisenberg, MD, MPH 1745

Special Report
A New Terminology for Left Ventricular Walls and Location of Myocardial Infarcts That Present Q Wave
Based on the Standard of Cardiac Magnetic Resonance Imaging: A Statement for Healthcare Professionals
From a Committee Appointed by the International Society for Holter and Noninvasive Electrocardiography
Antoni Bays de Luna, MD; Galen Wagner, MD; Yochai Birnbaum, MD; Kjell Nikus, MD; Miguel Fiol, MD;
Anton Gorgels, MD, PhD; Juan Cinca, MD; Peter M. Clemmensen, MD; Olle Pahlm, MD;
Samuel Sclarovsky, MD; Shlomo Stern, MD; Hein Wellens, MD; Wojciech Zareba, MD 1755

AHA Scientific Statement


Assessment of Coronary Artery Disease by Cardiac Computed Tomography: A Scientific Statement From
the American Heart Association Committee on Cardiovascular Imaging and Intervention, Council on
Cardiovascular Radiology and Intervention, and Committee on Cardiac Imaging, Council on Clinical
Cardiology
Matthew J. Budoff, MD, FAHA; Stephan Achenbach, MD; Roger S. Blumenthal, MD, FAHA;
J. Jeffrey Carr, MD, MSCE; Jonathan G. Goldin, MD, PhD; Philip Greenland, MD, FAHA;
Alan D. Guerci, MD; Joao A.C. Lima, MD, FAHA; Daniel J. Rader, MD, FAHA; Geoffrey D. Rubin, MD;
Leslee J. Shaw, PhD; Susan E. Wiegers, MD 1761

Circulation Electronic Pages


Images in Cardiovascular Medicine
Bilateral Sinus of Valsalva Aneurysms: An Extreme Case
Paraskevi A. Vlachou, MRCS; Ian Loke, MRCP; Derek Chin, FRCP; Christina Vlachou, MBChB;
Christos Alexiou, PhD, FRCS; Andrzej W. Sosnowski, FRCS; Iain B. Squire, FRCP;
Richard Keal, FRCR Web Site Feature e542 e543
Takayasus Arteritis: The Macaroni Sign
S. Meini, MD; V. De Franco, MD; A. Auteri, MD; D. Pieragalli, MD Web Site Feature e544
Vieussens Ring: Combining Computed Tomography Coronary Angiography and Magnetic Resonance
Imaging in Assessing Collateral Pathways
Mark W. Hansen, MBBS; Naeem Merchant, MD Web Site Feature e545 e546

Correspondence
Letter by Undas and Jakubowski Regarding Article, Relationship Between Homocysteine and Mortality in
Chronic Kidney Disease
Anetta Undas, MD, PhD, DSc; Hieronim Jakubowski, PhD, DSc Web Site Feature e547
Response to Letter Regarding Article, Relationship Between Homocysteine and Mortality in Chronic
Kidney Disease
Vandana Menon, MD; Mark J. Sarnak, MD; Arema A. Pereira, MD; Andrew S. Levey, MD;
Tom Greene, PhD; Xuelei Wang, MS; Gerald J. Beck, PhD; John W. Kusek, PhD; Jacob Selhub, PhD;
Allan J. Collins, MD; Michael G. Shlipak, MD Web Site Feature e548

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indicates articles with a Clinical Perspective; indicates articles available online only.
114 (16)

Circulation. 2006;114:f161-1791
Circulation is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231
Copyright 2006 American Heart Association, Inc. All rights reserved.
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