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INTERCELLULAR JUNCTIONS

 Means by which cells are fastened together


 For communication

Collection of cells held together by junctions make up tissues and organs that carry out related functions.

Types of Tissues

1. Epithelial – cover surfaces, line cavities and form glands.


2. Connective – support and form framework of all body parts (liquids, soft, fibrous, hard)
3. Excitable – muscle and nerves.
4. Glandular – make up diff. glands of body

(table of the types of epithelia will be provided by Dr. Viray)

CELL ADHESION MOLECULES – “CAMs”

 Are membrane spanning CHONs (supportive and spreading fxn) responsible for:
1. Cell-cell junctions
-essential for normal growth and development
Ex. Nerve-CAMs help growing nerve cells creep across extracellular matrix.
2. Transient Cell adhesions
-adhesions which are not permanent.
Bond between CAMs and matrix is weak.
Ex. CAMs help WBC escape circulation and move into infected tissues; CAMs allows clumps of platelets to cling to damaged blood
vessels.