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0764 Group 1

Magallanes, Maricris
Manuel, Einna
Milo, Juna
Mogamog, Trisha
Nacion, Kaela
1.

1.Source/ 4.Storage 5. Target 9. Duration


Hormone 2.Nature 3.Stimuli 6.Receptor 7. Action 8. Onset
Gland (+ or -) cell/gland of action
Anterior - Corticotropin Stimulate Between 11:00
1. Adrenocorticotr Adrenal Melanocortin-2 6:00 to 9:00
pituitary Protein releasing + secretion of PM and 3:00
opin cortex receptor AM
gland hormone glucocorticoids AM
Upon
- Sudden Controls the rate inhibition of
V1 (on blood
decrease of of water osmorecepto
vessels) and V2
blood pressure excretion into rs, and when
(in the
Posterior - Low blood the urine thus the blood
2. Antidiuretic basolateral
pituitary Protein volume + Kidneys helping to Rapid onset volume and
hormone membrane of
gland - Increased control the osmotic
the collecting
extracellular concentration of pressure of
tubule cells in
fluid water in the body fluids
the kidney
osmolarity body fluids return to
normal
Corticotropin
3. Corticotropin - Low blood releasing Releases
Hypothala Adrenal
releasing Protein levels of + hormone adrenocorticotro
mus cortex
hormone glucocorticoids receptors pic hormone
(GPCR)
From
Stimulates
follicular
development of
Anterior - Gonadotropin Start of phase up to
ovarian follicles
4. FSH pituitary Protein releasing + Gonad FSH receptor menstrual the luteal
and regulates
gland hormone cycle phase of the
spermatogenesis
menstrual
in the testis
cycle
GnRH receptors
in the pituitary
5. Gonadotropin Anterior
Hypothala - Embryonic gonadotroph Releases LH
releasing Protein + pituitary Puberty Lifetime
mus migration cells and and FSH
hormone gland
extrapituitary
tissues.
- Growth
hormone
releasing GHRH receptor Until blood
6. Growth
hormone Anterior in the pituitary glucose
hormone Hypothala Releases growth Hypoglycemic
Protein - Decreased + pituitary gland and in levels reach
releasing mus hormone state
blood glucose gland somatotroph normal
hormone
- Exercise cells levels
- Deep sleep
- Trauma, stress
- Gonadotropin Stimulates the The median Average LH
Anterior
releasing Leydig cells to interpulse peaks
7. LH pituitary Protein + Gonad LH receptor
hormone secrete interval is 55 duration is
gland
- Estrogen testosterone minutes 40 minutes
- Stretching of
the cervix of Vaginal and
Posterior the uterus Uterus, Oxytocin cervical
8. Oxytocin pituitary Protein - Sucking of an + Mammary receptor (class I distension Immediate 1 hour
gland infant gland GPCR) before and after
(mechanical birth
stimulus)
Anterior - Thyrotropin Menstrual
Prolactin Promotes milk Just before
9. Prolactin pituitary Protein releasing + Breast cycle and
receptor (PRLR) production menstruation
gland hormone pregnancy
10. Prolactin
Anterior
release Hypothala Inhibits release
Protein + pituitary D1,2,3,4,5
inhibiting mus of prolactin
gland
hormone
Secreted in
-Stimulates
pulses with an
body growth.
average
-Stimulates
interpulse
lipolysis
Anterior - Gonadotropin Growth interval of 2 to Requires
Most - Inhibits actions
11. Somatotropin pituitary Protein releasing + hormone 3 hours with months for
tissues of insulin on
gland hormone receptor most full effect
carbohydrate
reproducible
and lipid
peak occurring
metabolism
at the onset of
sleep
Stimulates the Up until
Anterior - Thyrotropin Thyrotropin
synthesis of there is
12. Thyrotropin pituitary Protein releasing + Thyroid receptor (TSH- Slow onset
thyroid elevation of
gland hormone R)
hormones T3, wherein
release of
TRH and
TSH will be
inhibited
Very short-
lived, lasting
for a matter of
Up until
two (2)
there is
minutes and
- Low levels of Releases thyroid elevation of
13. Thyrotropin Anterior Thyrotropin travelling less
Hypothala T3 and T4 or stimulating T3, wherein
releasing Protein + pituitary releasing than an inch in
mus low metabolic hormone (TSH) release of
hormone gland hormone the
rate and prolactin TRH and
bloodstream to
TSH will be
the pituitary
inhibited
gland before
it's broken
down.

1. Pathway for oxytocin action. Illustrate schematically the pathway for hormone action (includes 1-7 parameters of the table above)

References
Athabasca University, Faculty of Humanities and Social Sciences. (n.d.). Anterior Pituitary. Retrieved from BioTutorials:
https://psych.athabascau.ca/html/Psych402/Biotutorials/36/fig36b_frame.html

Birnbaurmer, M. (2000). Vasopressin receptors. Trends in Endocrinology & Metabolism, 406-410.

BIshop, M. L., Fody, E. P., & Schoeff, L. E. (2010). Clinical chemistry: Techniques, principles, correlations (6th ed.). Philadelphia, PA: Lippincott Williams & Wilkins.

Bishop, M. L., Fody, E. P., & Schoeff, L. E. (2013). Clinical Chemistry Principles, Techniques, and Correlations (7th ed.). Philadelphia,PA: Lippincott William &
Wilkins.

Burtis, C. A., Ashwood, E. R., & Bruns, D. E. (2008). Tietz Textbook of Clinical Chemistry and Molecular Diagnostics (6th ed.). Missouri: Elsevier.

Channing, C. P., & Tsafriri, A. (1997). Mechanism of action of luteinizing hormone and follicle-stimulating hormone on the ovary in vitro. Metabolism, 413-468.
Dufau, M. L. (1998). The luteinizing hormone receptor. Annual Review of Physiology, 461-496. doi:10.1146/annurev.physiol.60.1.461

Eroschenko, V. P. (2008). diFiore's atlas of histology with functional correlations (11 ed.). Philadelphia, PA: Lippincott Williams & Wilkins.

Gimpl, G., & Fahrenholz, F. (2001). The oxytocin receptor system: structure, function, and regulation. Physiological Reviews, 629-683.
doi:10.1152/physrev.2001.81.2.629

Hall, J. E., & Guyton, A. C. (2011). Guyton and hall textbook of medical physiology (12th ed.). Philadelphia, PA: Saunders Elsevier.

Malik, S., Dolan, T. M., Maben, Z. J., & Hinkle, P. M. (2015). Adrenocorticotropic hormone (ACTH) responses require actions of the melanocortin-2 receptor
accessory protein on the extracellular surface of the plasma membrane. The Journal of Biological Chemistry. doi:10.1074/jbc.M115.668491

NCBI. (2017, December 31). FSHR follicle stimulating hormone receptor [ Homo sapiens (human) ]. Retrieved from NCBI:
https://www.ncbi.nlm.nih.gov/gene/2492

NCBI. (2017, November 23). PRLR prolactin receptor [ Homo sapiens (human) ]. Retrieved from NCBI: https://www.ncbi.nlm.nih.gov/gene/5618

VanPutte, C., Regan, J., & Russo, A. (2016). Seeley's essentials of anatomy & physiology (9th ed.). New York: McGraw-Hill Education.

Welt, C. K. (2017). Physiology of gonadotropin-releasing hormone. Retrieved from UpToDate: https://www.uptodate.com/contents/physiology-of-gonadotropin-


releasing-hormone#H1

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