No Course Information

1. Course Name: HAEMATOLOGY ANDTRANSFUSIONSCIENCE

2. Course Code: UDDD2144
3. Classification: Core Major
4. Credit Hours: 4
5. Trimester/Year Offered: 1/2, 2/2 & 3/2
6. Pre-requisite (if any):
UDDD1124 Anatomy and Physiology I
UDDD1214 Anatomy and Physiology II
7. Mode of Delivery : Lecture, Tutorial and Practical
8. Assessment Methods:
Continuous Assessment
Tests/Quizzes/Assignments –25% 50%
Practical report/laboratory test – 25%
Final Examination 50%
9. Name(s) of Academic Staff:
• Ms Saw Seow Hoon
• Ms Annaletchumy a/p Loganathan
• Dr. Teh Lai Kuan
10. Course Objective:
This course aims to provide complete overview of the normal full blood picture and
changes in blood components due to congenital and acquired haematological disorders.
Make the students understand laboratory aspects of haematological disorders and in
blood transfusion.
11 Course Learning Outcomes:
After completing this course, students should be able to:
1. Describe the structure and function of normal blood components and their normal
values, and to identify the production of blood elements.
2. Explain and discover the type of anaemia by morphological classification and
diagnostic approaches.
3. Describe the nature of leukaemia and aetiological factors in leukaemia plus the
prognosis of leukaemia patients.
4. Identify the morphology and function of platelets and the investigation for the extent
of abnormal bleeding and coagulation disorders.
5. Illustrate the types and clinical features of lymphomas and discuss pathology arising
from marrow stem.
6. Identify the components of the blood that must be investigated before blood
transfusion and discuss the hazards of blood transfusion.
12. Course Synopsis:
This course provides students with basic science in haematology, haematopoiesis (red
blood cell, white blood cells and platelets), haematological disorders including red
blood cell disorders, white blood cells disorders, platelet disorders, coagulation
disorders, lymphomas, myeloproliferative disorders and blood transfusion. Laboratory
aspects of haematological investigations in diagnosis of disorders will be covered in
practical
13. Topics and Notional Hours:
Learning
T Outcomes L P T SL TLT
Topic1: Haematopoiesis and Relevant Cytokines 1 4 - 7 11
• Haematopoiesis
• Haematopoietic Stem Cells and Cytokines
• Red blood Cells Production
 • Platelets Production
Topic 2:RedBloodCellDisorders 2 5 1 8 14
• Anaemia
• Types of Anaemia
• Polycythaemia
Topic 3: White Blood Cell (WBC)Disorders 3 6 1 9 16
• Non-Neoplastic Disorders of WBC
• Neoplastic Proliferations of WBC
Topic4:Platelet Disorders 4 5 - 9 14
• Disseminated Intravascular Coagulation
• Thrombocytopenia
Topic5:CoagulationDisorders 4 4 1 7 12
• Deficiency of Coagulation Factors, Von Willebrand
and Others
Topic6:Lymphomas 5 5 - 7 12
• Hodgkin Lymphoma
• Non-Hodgkin Lymphoma
• Multiple Myeloma
Topic7: Myeloproliferative Disorders 5 6 - 7 13
• Polycythaemia
• Thrombocythaemia
• Myelofibrosis
• Myelodysplastic Syndrome
Topic 8: Introduction to Blood Transfusion Science 6 5 - 10 15
• Blood Groups
• ABO system
• Rhesus System
• Complications of Blood Transfusion
o Techniques for Antigen/Antibody Detection
o Pre-Transfusion Testing
o Quality Control in Haematology
Practical
Practical 1: Phlebotomy 2 2 2 4
Practical 2: Preparation and Staining of Peripheral 1, 2 2 2 4
Blood Film
Practical 3: Red Cell Count, White Cell Count, 3 2 2 4
Differential White Cell Count
Practical 4:Anaemia 2 2 2 4
Practical 5: Leukaemia 3 2 2 4
Practical 6: Basic Coagulation Screening Tests 4 2 2 4
Practical 7: Cross Matching (Tube Method) 6 2 2 4
Assessment - - 25 25
• Assignments/ Quizzes/ Tests
• Lab reports/Lab test
• Final Examination
Total Notional Hours 40 14 3 103 160

CreditHours 4
Main References:
1. Hoffbrand, A.V., Pettit, J., & Paul, M. (2011). Essential haematology. Malden, Mass:
Blackwell Publisher, 6th Edition.
2. Beutler,E.,Lichtman,M.A.,Coller,B.S.,&Kipps,T.J.(2010).Williams’shaematology.(8th
ed.).NewYork: McGraw-Hill.
Additional References:
1. Hoffbrand, A.V. (2009).Haematology at a glance. (3rded). Malden, Mass: Blackwell.
2. Hortward, M.R. & Hamilton, P. (2008). Haematology: An Illustrated color text: Churchill
Livingstone Elsevier, 3rd Edition.
Date of Senate’s Approval:
02nd February 2016

L = Lecture SL = Self- Learning

T = Tutorial TLT = Total Learning Time
P = Practical