Beta-glucan

immune
system
reconstruction
of the skin
prevent skin damage
infection irritation
 The Science of Skin Therapy

Beta-glucan consists of a 1,3-β-D-linked backbone of

glucose residues with 1, 6-β-D-glucosyl side groups.
 Beta-glucan, the raw material of BETA SÉRUM, is
a natural polymer produced by the fungus, Shiitake.
It is well known to boost epidermal cell growth
factors that promote Collagen Synthesis and Skin
Elasticity.

Beta-glucan has been widely used in various

areas such as cosmetics, food, and even in medicine.

BETA SÉRUM is highly concentrated beta-glucan.

It works excellent especially in soothing,
moisturizing, and giving anti-inflammatory
effects.

BETA SÉRUM is a great way to regenerate your

skin as it is capable of moisturizing for 20% higher
than what Hyaluronic acid can do.

BETA SÉRUM will help you restore soft, smooth,

and young skin.

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 Moisturizing Regeneration Elasticity Cooling

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 MOISTURIZING
1
Vitalize your face

It has been proved that Beta-glucan has higher water

contents than hyaluronic acid (More than 20%)

[ Moisture Increase of Beta-Glucan and Hyaluronic Acid]

60

40

20

0
Hyaluronic Beta-glucan BG+HA 20 mins
acid 120 mins
 COOLING
2
Cool sun-damaged skin

Measurement: Red Spot Level

Schizophy
Hour Comparis Example
GluCare-S llum
on Group 1
Extract

0 100.00 100.00 100.00 100.00

16 197.85 163.60 193.51 180.65

24 193.58 155.01 189.32 178.28

48 174.98 135.87 165.25 160.56

Schizophyllum-originated Beta-glucan
Glucare-S: Yeast-originated Beta-glucan

The schizophyllum-originated Beta-glucan showed higher

sun-burn treatment effects of 22.35%; whereas the yeast-
originated Beta-glucan had only 8.24% of treatment effects.

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 Rejuvenate / Heal
3
Calm your wound / burn marks

1) Swelling

2）Lacerations

3) Burns

4）After various operations

Thanks to anti-inflammatory effects, it can be applied directly

on the wound sites.

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 SAFETY
4
Safe your skin

No allergic reaction was observed during the

skin safety evaluation.

Safety Evaluation
Description (n=10) D0 D2 D5 D7 D12
Itchy 0 0 0 0 0
Sharp pain 0 0 0 0 0
Tickle 0 0 0 0 0
Subjective Stimulation Burning 0 0 0 0 0
Prick 0 0 0 0 0
Stiff 0 0 0 0 0
Tight 0 0 0 0 0
Red spots 0 0 0 0 0
Swelling 0 0 0 0 0
Objective Stimulation Scale 0 0 0 0 0
Pimple, rash, etc 0 0 0 0 0
Others 0 0 0 0 0
Total Side-effects 0 0 0 0 0

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 Absorption
5
Deep infiltration

Beta glucan rapidly reaches to the dermis layer without needle injection.

It has been demonstrated that (1,3)(1,6)-β-D-glucan can rapidly permiate into the
dermis layer of the mammalian epidermis

• Based on carbohydrate histochemical methods and the porcine ear skin

model, the study demonstrates the rapid permieation of (1,3)(1,6)-β-D-
glucans from a cosmetic formulation into the mamalian epidermis.
• (Meyer, Wilfried MD, Schonnagel, Britta MD. 2006, A note on integumental (1->3)(1->6)[Beta]-D-glucan
permation, using the porcine ear skin model. Journal of Cosmetic Dermatology. 5(2):130-134, 2006)

It has been proved that Beta-glucan can deeply penetrate the skin into the epidermis
and dermis layers despite its large molecular size

• Penetration studies performed on human abdominal skin used a single

application of 0.5% Beta-glucan solution at a dose of 5 mg per cm². The
results showed that Beta-glucan, despite its large molecular size, deeply
penetrated the skin into the epidermis and dermis.
• (R. Pilai, M. Redmond, J. Roding. 2005. Anti-Wrinkle Therapy: Significant New Findings in the Non-Invasive
Cosmetic Treatment of Skin Wrinkles with Beta-Glucan. IFSCC Magazine)

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 How to Use

1 After washing your face, apply BETA SÉ RUM on your face.

Gently tap the skin with your fingers until BETA SÉ RUM is
2 absorbed

3 Apply BETA SÉ RUM in the morning and evening (daily).

It is also convenient to use BETA SÉ RUM before wearing
makeup as BETA SÉ RUM is absorbed quickly into your
skin by simple finger-tapping.

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 Clinical Results of Beta-glucan

Pores Skin Tone Wrinkles Pores Pigmentation

Visible Pigmentation Right eye Visible Pigmentation
pores pores
Area Left eye Area
Large Large
pores pores
Pigmentation Pigment
Black Black ation
head Area head Area

Skin Tone Redness Shine Skin Tone Redness

Color Moisture Color
(0-360) Numbers (0-360) Numbers
Skin Oil
Contrast Contrast
(0-100) Area (0-100) Area
Brightness Brightness
(0-100) (0-100)

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 PRODUCT : BETA SÉ RUM (INTENSIVE HYDRATION BETA SÉ RUM)
VOLUME : 15ml * 3pcs/1box
INGREDIENTS : Water, Beta-glucan, Glycerin, 1,2-Hexanediol
EXPIRATION DATE : 2 years from the manufactured date / 12months after use
MANUFACTURE & DEALING : NeoGenesis Co., Ltd.
DIRECTIONS OF USE : Apply serum onto face after washing in the morning & evening.
Gently tap the applied area to allow the serum to be absorbed.
BENEFITS : Prevent skin damage and enhance the elasticity. Gives more
hydration than Hyaluronic Acid
PRECAUTION FOR USE : 1. Discontinue use if following signs or symptoms appear, and
consult your doctor: Rash, irritation, hives, itching, swelling, etc. 2.
Do not apply on the area if there are signs of eczema or dermatitis
at the site of the wound.
WARNING : 1. Close the lid completely after use 2. Keep out of reach of children
3. Do not store in humid or overheated place, and avoid direct
sunlight.

Product Information
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 NeoGenesis Co., Ltd.
#302, E&C Dream Tower, 146, Seonyu-ro, Yeongdeungpo-
gu, Seoul, South Korea (07255)
Tel. +82-2-583-1348 Fax. +82-2-2038-0848
Homepage: www.neogenesis.co.kr
Email: info@neogenesis.co.kr