Classification: OPIOID ANALGESICS

PRECAUTION/ NURSING
GENERIC CONTRAINDICATI
INDICATION ACTION ADVERSE CONSIDERATI
NAME ON
REACTION ON
(nalbuphine NUBAIN (nalbuphine Binds to opiate  Contraindica •CNS: Sedation, •Reassess
hydrochloride) hydrochloride) is receptors in the ted in dizziness, vertigo, patient’s level of
indicated for the relief of CNS, alters the patients headache, pain at least 15
BRAND NAME moderate to severe pain. perception of and hypersensitive to agitation, and 30
Nubain NUBAIN (nalbuphine responses to drug confusion, crying, minutes after
hydrochloride) can also painful stimuli while  Use cautiously in depression, parenteral
DOSE be used as a producing patients with dysphoria, administration
supplement to generalized CNS history euphoria, faintness, •Nalbuphine
5mg through IV balanced anesthesia, depression. floating feeling, acts as an
of drug abuse
for preoperative and pos
and in hallucinations, opioid
toperativeanalgesia, and
those with heaviness antagonist and
for obstetrical analgesia
emotional feeling, hostility, may
during labor and
instability, head nervousness, cause
delivery.
injury, increased numbness, withdrawal
ICP, restlessness, syndrome. For
impaired seizures, patients who
ventilation, tingling, unreality, have received
MI accompanied unusual dreams log-term
by •CV: Bradycardia, opioids, give
N/V, upcoming hypertension, 25% of the
biliary surgery, hypotension, usual dose
and tachycardia initially. Watch
hepatic or renal •EENT: Blurred for sings of
disease. withdrawal.
vision, dry •Alert: Drug
mouth causes
•GI: Nausea, respiratory
vomiting, depression,
biliary tract which at 10mg is
spasms, equal to
constipation respiratory
cramps, depression
dyspepsia produced by 10
mg of
•GU: Urinary morphine
urgency •Monitor
•Respiratory: circulatory and
Respiratory respiratory
depression, status, bladder
asthma, dyspnea, and bowel
pulmonary edema function. If
respirations are
shallow or
rate is below 12
breaths/minute,
withhold
dose and notify
prescriber
•Constipation is
often
severe with
maintenance
therapy.