Você está na página 1de 1

Artemisinin : Practically insoluble in water; very soluble in dichloromethane R;

freely soluble in acetone R and ethyl acetate R; soluble in glacial acetic acid R,
methanol R and ethanol (~750 g/l) TS.
Sediaan : Capsule (Available strength: 250mg.) Tablet (Available strength:
250mg.)

Artemether :
Practically insoluble in water; very soluble in dichloromethane R and acetone R;
freely soluble in ethyl acetate R and dehydrated ethanol
R.
sediaan : Capsule (Available strengths: 40 mg, 50mg.) Tablet (Available
strengths: 40 mg, 50mg) Injeksi i.m (Strength in the current WHO Model list of
essential drugs: 80 mg/ml in 1-ml ampoule; other available strengths: 40 mg/ml
(paediatric formulation), 60 mg/ml, 100 mg/ml (adult formulation).)

Arteether :
Practically insoluble in water; sparingly soluble in dichloromethane
R, ethanol (~750 g/l) TS and methanol R; soluble in arachis oil R and sesame oil
R.
Sediaan : Injeksi (Available strengths: 50 mg/ml (paediatric formulation), 75
mg/ml, 150 mg/ml (adult formulation). untuk i.m)

DHA :
Practically insoluble in water; slightly soluble in acetonitrile R,
ethanol (~750 g/l) TS and dichloromethane R.
Sediaan : Tablet (Available strength: 20mg)

Artesunate:
Very slightly soluble in water; very soluble in dichloromethane
R; freely soluble in ethanol (~750 g/l) TS and acetone R.
pH : pH of an aqueous suspension containing 10 mg/g, 3.5–4.5.
Sediaan : Tablet (trength in the current WHO Model list of essential
drugs: 50mg.)

(International Pharmacopoiea, 3rd Ed)

Você também pode gostar