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Read all of this leaflet carefully before affecting the brain or spinal cord which • suffer from depression
you start taking this medicine. causes weakness, un-coordinated • have suicidal thoughts
• K eep this leaflet. You may need to read movements, rigidity and stiffness) • have epilepsy or a history of seizures medicines (dependency) or can make you can cause diazepam to be removed from
it again. • helping to treat muscle spasm caused very sleepy. the body more slowly than usual.
• If you have any further questions, ask your by tetanus (when taken with other Other considerations • barbiturates such as phenobarbital (to •o ral contraceptives, as they can
doctor or pharmacist. medicines). • Mental side effects – contact your treat epilepsy and mental disorders) slow down the removal of diazepam
• This medicine has been prescribed for doctor if you experience side effects such •m edicines to lower high blood from the body and increase its effect.
you. Do not pass it on to others. It may Both adults and children can take as agitation, hyperactivity, restlessness, pressure, diuretics (water tablets), Breakthrough bleeding can occur when
harm them, even if their symptoms are Diazepam tablets before an operation aggressiveness, nightmares or nitrates (for heart conditions) as these taking diazepam and oral contraceptives
the same as yours. to help with relaxation and to cause hallucinations. These side effects are more could lower your blood pressure too together, but the contraceptive
• If any of the side effects gets serious, or sleepiness. likely to occur in children or the elderly. much. protection is not reduced.
if you notice any side effects not listed • Amnesia (total or partial memory loss) • a ntacids (reduces stomach acid) may • c isapride (used to treat stomach
in this leaflet, please tell your doctor or 2. Before you take – you could experience amnesia when slow down absorption of diazepam in problems), as it can cause diazepam to
pharmacist. Do not take Diazepam tablets and tell taking this medicine. Amnesia is more the body. be removed from the body more slowly
your doctor if you likely to occur when taking high doses of than usual.
In this leaflet: • are allergic (hypersensitive) to diazepam diazepam. Taking these medicines with diazepam • c orticosteroids (medicines used to treat
1. What Diazepam tablets are and what or to other benzodiazepine medicines • Dependence - when taking this medicine could affect your mental status, make you inflammation in the body) as they can
they are used for or to any of the other ingredients in your there is a risk of dependence, which very sleepy and suppress your breathing weaken the effect of diazepam.
2. Before you take tablets (see section 6) increases with the dose and duration and blood pressure. • l evodopa (used to treat Parkinson’s
3. How to take •b reathing problems, which may be of treatment and also in patients with a •d isulfiram (to treat alcohol addiction). disease). Diazepam can reduct the effect
4. Possible side effects severe, including slow and/or shallow history of alcoholism and drug abuse. Taking this medicine with diazepam of levodopa.
5. How to store breathing Therefore, you should take Diazepam could make you very sleepy and can • v alproic acid (used to treat epilepsy and
6. Further information • suffer from depression (with or without tablets for a short a period of time as cause diazepam to be removed from the mental disorders) as it can slow down the
anxiety) or hyperactivity possible. body more slowly than usual. removal of diazepam from the body and
• Tolerance – if after a few weeks you •m edicines for epilepsy e.g. increase its effect.
1. What Diazepam tablets are • have a phobia (a fear of a particular
notice that the tablets are not working phenobarbital, phenytoin and • k etamine (an anaesthetic) as diazepam
object or situation) or other mental illness
and what they are used for • have myasthenia gravis (a condition as well as they did when first starting carbamazepine, sodium valproate, increases the effect of ketamine.
Diazepam belongs to a group of medicines which causes muscles to weaken and treatment, you should speak to your (diazepam can affect the blood levels • l ofexidine (to help relieve symptoms
called benzodiazepines. Diazepam helps tire easily) doctor. of these medicines). Diazepam can when you stop taking opioids)
in the treatment of anxiety, muscle spasms • suffer from sleep apnoea (a sleep • Withdrawal – treatment should be furthermore affect how phenytoin works. • nabilone (to treat nausea and vomiting)
and convulsions (fits). disorder where you have abnormal gradually withdrawn. Withdrawal • t heophylline (to treat asthma and other • a lpha blockers or moxonidine (to lower
pauses in breathing during sleep) symptoms occur with Diazepam tablets breathing disorders), as it can weaken high blood pressure)
Diazepam tablets are used to treat a • have severe liver disorders even when normal doses are given for the effect of diazepam. As this can cause
number of conditions, including: • have porphyria (an inherited condition short periods of time. See Section 3, ‘If diazepam to be removed from the body Taking Diazepam tablets with food
In adults causing skin blisters, abdominal pain and you stop taking Diazepam tablets.’ more quickly than usual. and drink
• s hort term relief (2-4 weeks only) of brain or nervous system disorders) • c imetidine, omeprazole or Do not drink alcohol while you are taking
severe anxiety, which is an emotional • planning a pregnancy or are pregnant Taking other medicines esomeprazole (stomach acid reducing Diazepam tablets. Alcohol may increase
state where you may sweat, tremble, (see below Pregnancy and breast-feeding). Please tell your doctor or pharmacist medicines), as these can cause diazepam the sedative effects of Diazepam tablets
feel anxious and have a fast heart beat if you are taking or have recently taken to be removed from the body more and make you very sleepy.
and may occur alone or with insomnia Check with your doctor or pharmacist any other medicines, including medicines slowly than usual.
(trouble sleeping) or mental health before taking Diazepam tablets if you obtained without a prescription. Especially: • r ifampicin, to treat infections (an Grapefruit juice may increase the amount
problems • have a history of alcoholism or drug • antidepressants (e.g. fluvoxamine, antibiotic) as this can cause diazepam to of diazepam in your blood. If you are
• h elping muscles relax and for muscle abuse fluoxetine) be removed from the body more quickly elderly, suffer from cirrhosis or any of the
spasm and cerebral palsy (a condition • have problems with your heart and • antipsychotics such as clozapine (to treat than usual. The effect of diazepam can be conditions listed in section 2, this could
affecting the brain which causes lungs or have severe kidney failure mental problems) weakened. possibly increase the sedative effects of
movement problems and rigidity or • have someone close to you that has • antihistamines (to treat allergies) • a mrenavir, atazanavir, ritonavir, Diazepam tablets and you should speak to
stiffness) recently died • general anaesthetics delavirdine, efavirenz, indinavir, your doctor or pharmacist.
• e pilepsy (when taken with other • have low blood levels of a protein called • sedatives (used to give calming effects) nelfinavir or saquinavir (antivirals),
medicines) albumin • hypnotics (to help you sleep) fluconazole, itraconazole, Drinks containing caffeine may reduce the
•p atients with the symptoms of alcohol • have a personality disorder • erythromycin (an antibiotic) ketoconazole or voriconazole (anti- effects of diazepam.
withdrawal • have a poor blood supply to the brain • muscle relaxants (e.g. suxamethonium, fungal medicines) as these can cause
• helping to relax nervous dental patients. (arteriosclerosis) tubocurarin) diazepam to be removed from the body Pregnancy and breast-feeding
• are elderly Diazepam tablets can cause • some strong pain killers such as more slowly than usual and therefore You should not take Diazepam tablets
In children confusion and have effects on muscles morphine (opioids) may give you a increase the risk of side effects. As these if you are pregnant, planning to become
• h elping to treat tension and irritability causing falls and injuries. heightened sense of well being when can make you feel sleepy for longer or pregnant or are breast feeding. If you take
caused by cerebral spasticity (a condition • have breathing difficulties taken with diazepam, which can increase cause difficulty breathing. Diazepam tablets late in your pregnancy
associated with a disease or trauma • smoke your desire to continue taking these • i soniazid (used to treat tuberculosis), as it or during labour your baby might have