GCH KURAKUMA AXIS N'ALLIES OF

MENTHA
DNA Test Report Test Date: April 24th, 2018 embk.me/gchkurakumaaxisnalliesofmentha

GENETIC STATS
Wolfiness: 0.3 % LOW
Predicted adult weight: 18 lbs
Genetic age: 92 human years

TEST DETAILS
Kit number: EM-1979486
Swab number: 31001801034434

Registration: AKC NP04282105    

GCH KURAKUMA AXIS N'ALLIES OF
MENTHA
DNA Test Report Test Date: April 24th, 2018 embk.me/gchkurakumaaxisnalliesofmentha

MATERNAL LINE

Through GCH Kurakuma Axis N'Allies of Mentha’s mitochondrial DNA we can trace his mother’s ancestry back to where dogs and
people first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described
below the map.

HAPLOGROUP: A1a HAPLOTYPE: A17

A1a is the most common maternal lineage among Western Part of the large A1a haplogroup, this common haplotype is
dogs. This lineage traveled from the site of dog domestication found in village dogs across the globe. Among breed dogs, we
in Central Asia to Europe along with an early dog expansion find it most frequently in Labrador Retrievers, Boxers, and
perhaps 10,000 years ago. It hung around in European village Mastiffs.
dogs for many millennia. Then, about 300 years ago, some of
the prized females in the line were chosen as the founding
dogs for several dog breeds. That set in motion a huge
expansion of this lineage. It's now the maternal lineage of the
overwhelming majority of Mastiffs, Labrador Retrievers and
Gordon Setters. About half of Boxers and less than half of Shar-
Pei dogs descend from the A1a line. It is also common across
the world among village dogs, a legacy of European
colonialism.

Registration: AKC NP04282105    

GCH KURAKUMA AXIS N'ALLIES OF
MENTHA
DNA Test Report Test Date: April 24th, 2018 embk.me/gchkurakumaaxisnalliesofmentha

PATERNAL LINE

Through GCH Kurakuma Axis N'Allies of Mentha’s Y chromosome we can trace his father’s ancestry back to where dogs and people
first became friends. This map helps you visualize the routes that his ancestors took to your home. Their story is described below
the map.

HAPLOGROUP: A1b HAPLOTYPE: Ha.8

For most of dog history, this haplogroup was probably quite Part of the A1b haplogroup, this rare haplotype occurs most
rare. However, a couple hundred years ago it seems to have often in Schipperkes and village dogs in Croatia.
found its way into a prized male guard dog in Europe who had
many offspring, including the ancestors of many European
guard breeds such as Doberman Pinchers, St. Bernards, and
Great Danes. Despite being rare, many of the most imposing
dogs on Earth have it; strangely, so do many Pomeranians!
Perhaps this explains why some Poms are so tough, acting like
they're ten times their actual size! This lineage is most
commonly found in working dogs, in particular guard dogs.
With origins in Europe, it spread widely across other regions as
Europeans took their dogs across the world.

Registration: AKC NP04282105    

GCH KURAKUMA AXIS N'ALLIES OF
MENTHA
DNA Test Report Test Date: April 24th, 2018 embk.me/gchkurakumaaxisnalliesofmentha

TRAITS
Coat Color  

E Locus (Mask, Grizzle, Recessive Red) EE

K Locus (Dominant Black) KBky
A Locus (Agouti, Sable) aa
D Locus (Dilute, Blue, Fawn) DD
B Locus (Brown, Chocolate, Liver, Red) BB

Other Coat Traits Other Body Features

Furnishings / Improper Coat (RSPO2) II Brachycephaly (BMP3) AA

Long Haircoat (FGF5) GG Natural Bobtail (T) CC
Shedding (MC5R) CC Hind Dewclaws (LMBR1) CC
Curly Coat (KRT71) CC

Performance
Body Size Altitude Adaptation (EPAS1) GG
Body Size - IGF1 II
Body Size - IGF1R GG
Body Size - STC2 TT
Body Size - GHR (E195K) GG
Body Size - GHR (P177L) CC

Genetic Diversity

Inbreeding Coefficient 34% MHC Class II - DLA DRB1 MHC Class II - DLA DQA1 and DQB1
Low Diversity High Diversity

Registration: AKC NP04282105    

GCH KURAKUMA AXIS N'ALLIES OF
MENTHA
DNA Test Report Test Date: April 24th, 2018 embk.me/gchkurakumaaxisnalliesofmentha

CLINICAL TRAITS
These clinical genetic traits can inform clinical decisions and diagnoses. These traits do not predict a disease state or increased
risk for disease. We currently assess one clinical trait: Alanine Aminotransferase Activity.

Alanine Aminotransferase Activity result: Low Normal

GCH Kurakuma Axis N'Allies of Mentha has two copies of a mutation associated with reduced ALT activity. Please inform your
veterinarian that GCH Kurakuma Axis N'Allies of Mentha has this genotype, as ALT is often used as an indicator of liver health and
GCH Kurakuma Axis N'Allies of Mentha is likely to have a lower than average resting ALT activity. As such, an increase in GCH
Kurakuma Axis N'Allies of Mentha’s ALT activity could be evidence of liver damage, even if it is within normal limits by standard ALT
reference ranges.

More information on Alanine Aminotransferase Activity:

Known to be highly expressed in liver cells, activity levels of alanine aminotransferase, or ALT, is a common value on most blood
chemistry panels and is known to be a sensitive measure of liver health. Dogs with two ancestral G alleles show "normal" activity.
Dogs that have one or two copies of the derived A allele may have lower resting levels of ALT activity, known as "low normal". If your
dog's result is "low normal" then when a blood chemistry panel is being interpreted the values that you and your veterinarian
consider "normal" may need to be adjusted. Please note that neither a "normal" nor a "low normal" result for this predicts a disease
state or increased risk for liver disease. Moreover, this mutation does not associate with increased levels of ALT: If your dog has
high ALT levels, please consult your veterinarian.

Registration: AKC NP04282105    

GCH KURAKUMA AXIS N'ALLIES OF
MENTHA
DNA Test Report Test Date: April 24th, 2018 embk.me/gchkurakumaaxisnalliesofmentha

HEALTH
Good news! GCH Kurakuma Axis N'Allies of Mentha did not test positive for
any of the genetic diseases that Embark screens for. 0 0
AT RISK CARRIER

Registration: AKC NP04282105    

GCH KURAKUMA AXIS N'ALLIES OF
MENTHA
DNA Test Report Test Date: April 24th, 2018 embk.me/gchkurakumaaxisnalliesofmentha

OTHER CONDITIONS
Good news! GCH Kurakuma Axis N'Allies of Mentha tested clear for 8 other common genetic diseases that Embark tests for.

Multidrug Sensitivity Von Willebrand Disease Type II

(MDR1) (VWF Exon 28)

Progressive Retinal Atrophy (PRA) Primary Lens Luxation

Progressive rod-cone degeneration (PRCD Exon 1) (ADAMTS17)

Hyperuricosuria and Hyperuricemia or Urolithiasis Degenerative Myelopathy

(SLC2A9) (SOD1A)

Dilated Cardiomyopathy Exercise-Induced Collapse

(PDK4) (DNM1)

Registration: AKC NP04282105    

GCH KURAKUMA AXIS N'ALLIES OF
MENTHA
DNA Test Report Test Date: April 24th, 2018 embk.me/gchkurakumaaxisnalliesofmentha

FULL TEST PANEL

To help ensure healthy breeds, every test includes analysis of our full panel of over 160 genetic diseases.

GCH Kurakuma Axis N'Allies of Mentha is also clear of 156 other genetic
diseases that Embark tests for.

Registration: AKC NP04282105