San Beda College

COLLEGE OF NURSING
P.O. BOX 4457 1005 MANILA, PHILIPPINES TELEFAX: 735-6011 to 15 Loc. 4131
DRUG STUDY
GENERIC NAME: EPINIPHRINE BRAND NAME: Bronkaid Mist, Epinephrine Pediatric, EpiPen Auto-Injector
Route of Administration: SC, IV Dosage: Adult:IV 0.1–1 mg q5min as needed Intracardiac 0.1–1 mg (cardiac arrest)
Available Stock: 1 mg/ml in 2 ml ampule
DRUG CLASS MODE OF INDICATIONS/ ADVERSE DRUG NURSING HEALTH
ACTION CONTRA REACTIONS TO INTERACTIONS CONSIDERATIONS TEACHINGS
INDICATIONS WATCH OUT FOR
AUTONOMIC Body as a Whole: Drug: May increase
NERVOUS SYSTEM Naturally occurring Uses Monitor BP, pulse, Learn how to
catecholamine Nervousness, hypotension in administer epinephrine
AGENT; ALPHA- AND respirations, and
obtained from animal Temporary relief of restlessness, circulatory collapse or urinary output and subcutaneously. Keep
BETA-ADRENERGIC
adrenal glands; also bronchospasm, sleeplessness, fear, hypotension caused by medication and
AGONIST; observe patient
BRONCHODILATOR prepared acute asthmatic anxiety, tremors, PHENOTHIAZINES, closely following IV equipment available
synthetically. Acts attack, mucosal severe headache, oxytocin, entacapone. for home emergency.
administration. Confer with physician.
directly on both alpha congestion, cerebrovascular Additive toxicities with Epinephrine may
and beta receptors; hypersensitivity accident, weakness, other widen pulse Report tolerance to
the most potent and dizziness, syncope, SYMPATHOMIMETICS
pressure. If physician; may occur
activator of alpha anaphylactic pallor, sweating, (albuterol, with repeated or
receptors. disturbances in
reactions, dyspnea. Digestive: dobutamine, prolonged use.
Strengthens cardiac rhythm
syncope due to Nausea, vomiting. dopamine, Continued use of
myocardial occur, withhold
heart block or Cardiovascular: isoproterenol, epinephrine in the
contraction; increases epinephrine and
carotid sinus Precordial pain, metaproterenol, presence of tolerance
systolic but may notify physician
hypersensitivity, palpitations, norepinephrine, can be dangerous.
decrease diastolic immediately.
and to restore hypertension, MI, phenylephrine,
blood pressure; tachyarrhythmias phenylpropanolamine Take medication only
increases cardiac rate cardiac rhythm Keep physician as prescribed and
in cardiac arrest. including ventricular , pseudoephedrine, informed of any
and cardiac output. immediately notify
Relaxes fibrillation. ritodrine, salmeterol, changes in intake- physician of onset of
myometrium Respiratory: terbutaline), MAO output ratio. systemic effects of
and inhibits Bronchial and INHIBITORS, epinephrine.
uterine pulmonary edema. TRICYCLIC Use cardiac monitor
contractions; Urogenital: Urinary ANTIDEPRESSANTS. with patients Discard discolored or
prolongs action retention. Skin: ALPHA- AND BETA- receiving precipitated solutions.
ADRENERGIC
and delays Tissue necrosis with BLOCKING AGENTS epinephrine IV.
systemic repeated injections. Have full crash cart
absorption of immediately
local and
intraspinal
anesthetics.
Used topically
to control
superficial
bleeding.
 Contraindications Metabolic: (e.g., ergotamine, available. Do not breast feed
Metabolic acidoses, propranolol) while taking this
Hypersensitivity to elevated serum lactic antagonize effects of Check BP repeatedly drug without
sympathomimetic acid, transient epinephrine. when epinephrine is consulting physician.
amines; narrow- elevations of blood GENERAL administered IV
glucose. Nervous ANESTHETICS
angle glaucoma; during first 5 min,
System: Altered increase cardiac
hemorrhagic, then q3–5min until
state of perception irritability.
traumatic, or stabilized.
cardiogenic shock; and thought,
cardiac dilatation, psychosis. Advise patient to
cerebral report to physician if
arteriosclerosis, symptoms are not
coronary relieved in 20 min or
insufficiency, if they become worse
arrhythmias, organic following inhalation.
heart or brain
Advise patient to
disease; during
report bronchial
second stage of
irritation,
labor; for local
nervousness, or
anesthesia of fingers,
sleeplessness.
toes, ears, nose,
Dosage should be
genitalia. Safety
reduced.
during pregnancy
(category C) or Monitor blood
lactation is not glucose & HbA1c for
established. loss of glycemic
control if diabetic.

Agatha Christie Cabrera, GRP. 5 _________________________________

STUDENT CLINICAL INSTRUCTOR