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Source Citation:
https://www.genome.gov/pages/education/genetictimeline.pdf
Timeline Citation:
Genetic Timeline. (n.d.). Retrieved February 13, 2018, from
https://www.genome.gov/pages/education/genetictimeline.pdf
Timeline Events
● 1911 - Chromosomes carry genes
○ Description: Thomas Hunt Morgan and his students studied fruit fly
chromosomes.
○ Importance: The importance of this is it led to the understanding that
chromosomes carry genes which carry our traits. This then led to the
discovery genetic linkage and how it correlates to our understanding of
the various phenotypes seen in humans. The human genome project
would later expand upon this idea by sequencing the entire genome
and the many traits within it.
○ Image source
● 1975 - DNA sequencing
○ Description of the discovery: Frederick Sanger, Alan Maxam, and Walter
Gilbert create the Sanger method of DNA sequencing. This method
uses dyes that bind to the four nucleic acids present in DNA.
○ Importance of the discovery: This discovery allowed us to analyze DNA
in a simpler manner. From this we were able to identify the different
nucleotide combinations that compose various DNA strands with said
DNA strands being part of the genes that compose our genome.
○ Image source
● 1987 - First Human Genetic Map
○ Description of the discovery: The first detailed map of the variations in
DNA sequence. This is done by taking a strand of DNA and breaking it
up with restriction enzymes to better identify & map out specific
sequences.
○ Importance of the discovery: This map allows geneticists to quickly
locate the genetic link of certain diseases. This would allow for
geneticists to have a baseline at which to plot larger genetic systems,
like the entire human genome.
○ Image source
● 1990 - Human Genome Project
○ Description: The Department of Energy and the National Institutes of
Health announced a plan for a 15-year project to sequence the human
genome.
○ Importance: This will eventually result in sequencing all 3.2 billion
letters of the human genome which will help us identify traits that
correlate with specific diseases.
○ Image source