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Jessica, a 28 year old married second year medical resident at a large hospital, is in
psychological distress. She is normally a high achiever, performing very well in both college and
medical school and is very self-critical if she falls short of the high standards she sets for herself.
Currently she is struggling with feelings of worthlessness and shame because she is unable to
perform as well as she has in the past. Based on the specifics of Jessica’s case, it can be
concluded that she is likely suffering from major depressive disorder, that she is responding to
this through the psychoanalytic process of denial, and that a possible path of treatment for Jessica
The disorder that Jessica is presenting with is major depressive disorder. Symptoms for
major depressive disorder include depressed mood most or all of the time, dramatically reduced
thinking repetitively of death or suicide. If someone has been experiencing at least 5 of these
symptoms over a two week period of time and one of the 5 symptoms is depressed mood or
reduced interest they likely have major depressive disorder. Jessica has for the past few weeks
work, and insomnia. In addition her frequent tearful phone conversations, unusual irritable and
withdrawn demeanor, and tendency to call in sick and spend all day in bed indicate that she is
dealing with a depressed mood. These 5 symptoms are sufficient to demonstrate that Jessica is
questioned by her husband about her tearful conversations with her friend, instead of opening up
about her feelings of worthlessness and shame about her inability to perform to the standards she
is used to in her job, Jessica instead denies this reality. She lies to him and tells him everything is
fine. This denial is likely because acknowledging the fact that she is not able to meet her own
standards is painful.
Therapy (CBT). CBT seeks not only to alter thought processes but also behaviors. The therapy
operates by typically seeking to change behaviors and then focus on cognitive change. CBT is
often used to treat depressive disorders, helping people to replace harmful thought patterns with
more appropriate appraisals of their situations and encouraging them to practice behaviors
“incompatible with their problem” (Myers 669). In Jessica’s case, CBT might be used to address
her thoughts of worthlessness and shame and help her replace her negative responses to stress
and low mood (staying in bed, being irritable, not being open with her husband) with more
positive behaviors.
Jessica’s major depressive disorder is having a significant impact on her life. She presents
with the requisite 5 symptoms to qualify for the disorder, which is causing strain in her
relationships with her coworkers and husband and impacting her work performance. Because she
finds it painful to acknowledge that she is struggling with feelings of worthlessness because she
can’t meet her own standards, she denies that anything is wrong when confronted by her
husband. The best way to address these issues is through CBT. Both Jessica’s harmful thought
patterns and her harmful behaviors can be addressed through this process.
Alan Eiland 5/5/2018
Preventing the onset of major depressive disorder: A meta-analytic review of psychological interventions
Kim van Zoonen Claudia Buntrock David Daniel Ebert Filip SmitCharles F Reynolds, III Aartjan TF
International Journal of Epidemiology, Volume 43, Issue 2, 1 April 2014, Pages 318–329,
https://doi.org/10.1093/ije/dyt175
Published: 22 April 2014
Abstract
Background Depressive disorders are highly prevalent, have a detrimental impact on the quality of life of patients
and their relatives and are associated with increased mortality rates, high levels of service use and substantial
economic costs. Current treatments are estimated to only reduce about one-third of the disease burden of depressive
disorders. Prevention may be an alternative strategy to further reduce the disease burden of depression.
Methods We conducted a meta-analysis of randomized controlled trials examining the effects of preventive
interventions in participants with no diagnosed depression at baseline on the incidence of diagnosed depressive
Results We found that the relative risk of developing a depressive disorder was incidence rate ratio = 0.79 (95%
confidence interval: 0.69–0.91), indicating a 21% decrease in incidence in prevention groups in comparison with
control groups. Heterogeneity was low (I2 = 24%). The number needed to treat (NNT) to prevent one new case of
depressive disorder was 20. Sensitivity analyses revealed no differences between type of prevention (e.g. selective,
indicated or universal) nor between type of intervention (e.g. cognitive behavioural therapy, interpersonal
Conclusions Prevention of depression seems feasible and may, in addition to treatment, be an effective way to delay
or prevent the onset of depressive disorders. Preventing or delaying these disorders may contribute to the further
reduction of the disease burden and the economic costs associated with depressive disorders.