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ORIGINAL RESEARCH

International Journal of Surgery 10 (2012) 470e474

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International Journal of Surgery


journal homepage: www.theijs.com

Original research

Accuracy of FAST scan in blunt abdominal trauma in a major London


trauma centre
Simon Fleming a, Ruth Bird b, Kumaran Ratnasingham c, Shah-Jalal Sarker d, Mike Walsh e, Bijen Patel e, *
a
Barts and the London NHS Trust, Whitechapel, London E1 1BB, UK
b
Colchester NHS Trust, Turner Road, Colchester, Essex CO4 5JL, UK
c
Surgical Skills and Science, Barts Institute of Cancer, Old Anatomy Building, Charterhouse Square, London EC1M 6BQ, UK
d
Biostatistics, Centre for Experimental Cancer Medicine, Barts Cancer Institute, Barts and the London NHS Trust, Whitechapel, London E1 1BB, UK
e
Academic Department of Upper GI Surgery, Barts Institute of Cancer - a CR-UK Centre of Excellence, Queen Mary University of London, Old Anatomy Building,
Charterhouse Square, London EC1M 6BQ, UK

a r t i c l e i n f o a b s t r a c t

Article history: Introduction: Blunt abdominal trauma (BAT) is a leading cause of morbidity and mortality. Rapid diag-
Received 16 November 2011 nosis and treatment with the Advanced Trauma Life Support guidelines are vital, leading to the devel-
Received in revised form opment of Focused Assessment with Sonography in Trauma (FAST).
19 April 2012
Methods: A retrospective study carried out from January 2007e2008 on all patients who presented with
Accepted 22 May 2012
BAT and underwent FAST scan. All patients subsequently had a CT scan within 2 h of admission or
Available online 30 May 2012
a laparotomy within two days. The presence of intra-peritoneal free fluid was interpreted as positive.
Results: 100 patients with BAT presented; 71 had complete data. The accuracy of FAST in BAT was 59.2%;
Keywords:
Ultrasound
in these 31 (43.7%) were confirmed by CT and 11 (15%) by laparotomy. There were 29 (40.8%) inaccurate
Trauma FAST scans, all confirmed by CT. FAST had a specificity of 94.7% (95% CI: 0.75e0.99) and sensitivity of
Computerised tomography 46.2% (95% CI: 0.33e0.60). Positive Predictive Value of 0.96 (0.81e0.99) and Negative Predictive Value of
Abdominal injuries 0.39 (0.26e0.54). Fisher’s exact test shows positive FAST is significantly associated with Intra-abdominal
London pathology (p ¼ 0.001). Cohen’s chance corrected agreement was 0.3. 21 out of 28 who underwent
laparotomies had positive FAST results indicating accuracy of 75% (95% CI: 57%e87%).
Conclusion: Patients with false negative scans, requiring therapeutic laparotomy is concerning. In
unstable patients FAST may help in triaging and identifying those requiring laparotomy. Negative FAST
scans do not exclude abdominal injury. Further randomised control trials are recommended if the role of
FAST is to be better understood.
Ó 2012 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

1. Introduction that large amounts of blood can build up in the peritoneum before
such positive signs and symptoms can be detected on physical
Blunt abdominal trauma is a leading cause of both morbidity examination alone. A retrospective study by Schurink et al in 1997
and mortality in patients in the emergency department.1 Rapid showed that abdominal examination produced equivocal results in
diagnosis and treatment are considered vital in the successful nearly half the patients with multiple injured trauma patients.2
management of the trauma patient, as missed injuries can lead to This highlighted the need for further investigations in order to
preventable deaths. aid better management.
All trauma patients are assessed and managed according to the Multi-slice CT scans can produce very detailed images, are non-
ATLS guidelines. Information from the primary survey combined invasive and have become the gold standard investigation in
with examination of the abdomen is used to detect the likelihood of assessing blunt abdominal trauma. With the development of helical
possible injuries and tailor management plans. Abdominal pain/ CT, the scan time has been significantly reduced, improving its
tenderness together with observations such as blood pressure are usefulness with a sensitivity and specificity of over 95% in detecting
used in assessment to detect injury, however a limitation of this is intra-abdominal injury and a high negative predictive value of
nearly 100%.3 It is also useful for localising, identifying and
assessing severity of solid organ injury helping guide the non-
* Corresponding author. Tel.: þ44 7710678506; fax: þ44 2071016584. operative management or surgical planning.4 The development
E-mail address: b.patel@qmul.ac.uk (B. Patel). of contrast enhancement helical CT has enabled more accurate

1743-9191/$ e see front matter Ó 2012 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.
doi:10.1016/j.ijsu.2012.05.011
ORIGINAL RESEARCH

S. Fleming et al. / International Journal of Surgery 10 (2012) 470e474 471

arterial/mesenteric injury detection and can be used to guide No prospective trials have been performed in relation to FAST
surgical or angiographic intervention.5 It has also been shown to scanning and so it has been adopted into current practise with the
improve bowel injury and retroperitoneal organ injury detection entire evidence base being retrospective. The implications of this
rates.6 are that we are still learning how effective it is, both as a diagnostic
CT scans do however have their limitations and disadvantages. tool and in changing the management of patients.
The principal one being the need to transfer the patient to the There seems to be no consensus for training for FAST scanning,
scanner from the emergency department, making it unsuitable in with the variation being from 1hr practical session to over 200
unstable patients. Paediatric patients often require sedation, which, supervised scans.18e20 A Study by Shackford et al22 has shown that
means constant monitoring for risk of airway compromise. The the learning curve plateaus if trained properly after 10 scans,
procedure also requires specialised radiographers to perform the however others showed that it took approximately 50 scans for the
investigation and radiologists to interpret the images. Contrast learning curve to plateau.23 There is no consensus on how people
agents are known to cause allergic reactions in some patients. It should be trained and no consistency in their assessment. However,
should also be noted that a conventional anterioreposterior in the UK it was recommended by the Royal College of Radiolo-
abdominal x-ray examination results in a dose to the stomach of gists38 that all Emergency physicians undertake FAST scan training
approximately 0.25 mGy, which is at least 50 times smaller than the and this has been adopted by the College of Emergency Medicine
corresponding stomach dose from an abdominal CT scan.37 Also in training curriculum.39 It is also agreed that training should
abdominal CT effective radiation dose is the equivalent of 400 chest comprise of both theoretical and practical components with
x-rays and the equivalent of 2.7 years worth of natural radiation continuous review by a mentor.21 A study by McKenney has shown
dose. This is, however, balanced out in terms of risk: benefit as that the quality of the scan is no different whether performed by
accurate diagnosis in these acute traumas far outweighs the a radiologist, surgeon or emergency physician24 leading to the
possible radiation risk.40 training of all 3 specialties.
The need for a prompt diagnostic technique that could be used This pragmatic, retrospective observational study was under-
in the emergency setting led to the introduction of focused taken to determine how the results of FAST scans were used in
assessment with sonography in trauma (FAST) in emergency a routine inner city emergency department and whether they
departments in the 1990’s. It is undertaken after the primary survey influenced the subsequent treatment of adult, blunt trauma
in order to identify the presence of free fluid in the peritoneal patients.
cavity, which may represent haemoperitoneum, and thus enable
early referral for further imaging (CT), and/or surgery if necessary.1 2. Methods

Studies have shown that FAST can pick up as little as 100 ml of free
This paper reports a retrospective study carried out at a leading trauma centre,
fluid, characterised by low echogenicity which appears black on the Royal London Hospital, from Jan 2007eJan 2008. It included all patients aged
screen, or blood which is of increased echogenicity.7 There is some over 18 years who presented with blunt abdominal trauma and underwent a FAST
evidence to suggest it can detect as little as 30 ml of free fluid, but scan on arrival in the emergency department. Inclusion criteria required all patients
to then have had a CT scan within 2 h of admission or those who underwent
100 ml is generally considered to be the level at which FAST scan-
a laparotomy within the next two days. Patients with incomplete FAST, CT or clinical/
ning is accurate.8 Knowing that a patient has free fluid suggests the surgical notes were excluded. The FAST scans were performed by emergency
possibility of severe intra-peritoneal haemorrhage and supports physicians ranging from 1st year SPR, to staff grades to consultants, depending on
the case for further management, such as an emergency CT and/or their availability. These findings were documented in medical notes and along with
surgery. Haemodynamically stable patients may be sent for CT the assessment of solid organs. The presence of free fluid or intra-peritoneal fluid
was interpreted as a positive fast scan. Contrast CT images were obtained from the
scanning in order to assess the origin and extent of injury so as to
xiphoid to the symphysis pubis. The scans were immediately viewed by an on call
achieve prompt and appropriate management, whilst haemody- radiologist ranging from 1st year SPR to consultant. However, a consultant reviewed
namically unstable patients may be taken directly to the operating all images at a later date. PACS was used to retrieve these reports and data input from
theatre for emergency laparotomy where a lack of formal, medical notes collected on a standardised collection form.
comprehensive imaging could potentially lengthen the theatre
time as the site and extent of injury is unknown. Unlike FAST scan, 3. Analysis
CT’s are able to detect solid organ injury, however a large study by
Fakhry et al in 2003 showed that nearly 15% of patients with Fast reports were compared with CT scan reports if performed
perforated small bowel injury had a normal pre-operative CT scan within 2 h of the initial scan. If CT scans were not performed then
so they are not without limitation.9 In unstable patients where time FAST scans were compared with laparotomy findings if present.
is critical, ultrasound is quick and can be done at the bedside,
several observational studies have shown its utility as a screening 4. Results
test in this setting.10e14 However, in stable patients the position of
FAST in the diagnostic algorithm has not been well established. It 100 patients with Blunt Abdominal Trauma were seen in the
has been shown to compare unfavorably with computerized Royal London Hospital emergency department between January
tomography (CT) when detecting injuries, so missed injuries are 2007 to January 2008. A total of 80 medical notes were retrieved, 9
a major concern.15e17 of these were unsuitable for the study as 6 were hospital transfers
FAST’s ability to detect free fluid rapidly and in a non-invasive and 3 had no FAST scan, therefore a total of 71 patients were
manner has made it more attractive than other ‘in department’ included.
tests such as diagnostic peritoneal lavage which carries risks of 62% of these were male patients. The mean age of participants
perforation, infection and bleeding. Despite apparent ease of use was 41 years with a standard deviation of 19 (range 18e83). Assault
and accessibility, the accuracy of FAST scan is related to the was the most common cause (32%) followed by falls (28%) and
machine, the operator and the patient. Body shape, obesity and motor vehicle accident (14%).
surgical emphysema can make scans difficult to perform and
without a skilled operator, FAST has potential for misinterpretation 5. Accuracy of FAST scan
or, misdiagnosis.
Despite the popularity of FAST, there remains a lack of clarity The accuracy/inaccuracy of FAST scan was calculated. 84.5% of
and evidence around any actual contribution to patient survival.1 cases were confirmed by CT and on 15.5% were confirmed by
ORIGINAL RESEARCH

472 S. Fleming et al. / International Journal of Surgery 10 (2012) 470e474

laparotomy findings. The accuracy of FAST in BAT was 59.2%. Out of The historical data available from studies performed in the early
the 42 accurate cases, 31 (43.7%) were confirmed on CT and 11 (15%) days of FAST scan usage in a trauma setting, primarily during the
were confirmed at laparotomy. There were a total of 29 (40.8) 1990s, put FAST scan in a positive light, which lead to the American
inaccurate FAST scans, all of which were confirmed by CT. College of Surgeons recommending FAST as an alternative to
All the FAST scans were divided into 4 groups; diagnostic peritoneal lavage or CT and was held in such high regard
that it was integrated into the Acute Trauma Life Support (ATLS)
1. positive scans with pathology present (on CT or laparotomy) program and in Germany was made a compulsory part of the
2. positive scan but without intra-abdominal pathology surgical residency training program.
3. negative scan but with intra-abdominal pathology actually With all of the successful studies being published in relation to
present FAST scan, Chiu et al. raised valid concerns regarding the sensitivity
4. negative scan without pathology. of FAST. Their study showed 50 out of 196 patients with free fluid on
CT did not have detectable fluid on FAST scan.25 This early work
Table 1 shows that specificity of FAST scanning was high at 94.7% correlates precisely with the real time experiences of this study
(95% CI: 0.75e0.99), with a sensitivity of 46.2% (95% CI: 0.33e0.60). (Tables 1 and 2). Kathirkamanathen et al found that more than 25%
It also shows a Positive Predictive Value of 0.96 (0.81e0.99) and of patients with visceral injuries did not have free fluid on FAST scan
a Negative Predictive Value of 0.39 (0.26e0.54).Fisher’s exact test taken at admission, though the data from this study was insignif-
shows that FAST result is significantly associated with the Intra- icant in terms of these findings. Therefore the reliance of detecting
abdominal pathology (p ¼ 0.001). Cohen’s chance corrected free fluid by FAST does have its limitations and the clinicians are
agreement between the FAST scans and actual CT/Laparotomy was clearly aware of this and must use it within the context of a full
0.3 which is fair41. clinical assessment. The data showed that the trauma teams are
22 out of the 28 patients who had therapeutic laparotomies aware of these limitations and the need for assessment and reas-
were found to have positive FAST scan results. That is a 75% accu- sessment as evidenced by the number of patients who went on to
racy (95% CI: 57%e87%) of FAST in detecting intra-abdominal injury further intervention, regardless of their FAST result.26
that required therapeutic laparotomy. Indicating a 25% false nega- It has in fact been suggested that the true usefulness of FAST was
tive in FAST scan. in the context of hypotensive patients and that it could instead be
used to ‘triage’, rather than diagnose, patients to laparotomy or
further clinical evaluation or investigation.27e29
5.1. Incidental solid organ analysis In this study, the sensitivity of FAST scans in detecting free fluid
was 46.2% with 28/71 false negatives. 7 of these false negative
FAST results were compared to CT or laparotomy findings for patients went on to require a therapeutic laparotomy. This does
detecting solid organ injury (Liver and/or spleen) and again for strongly suggest that even at a Major Trauma Centre, FAST scan can
retroperitoneal injury (renal or adrenal). Only one case of retro- miss serious injury, if used in isolation.
peritoneal injury was detected by FAST with 89% of injury to A study by Moylan et al showed that 25 out of 33 (75.8%
kidneys or adrenal glands not being detected (1 case out of 11). Only sensitivity) therapeutic laparotomies had positive FAST scan.30
38.5% (10 cases out of 26 patients with injuries) of solid organ These findings are again, very similar to the data from the Royal
injury (Liver or spleen) were detected by FAST. London (Table 2) and raise similar concerns regarding the possi-
bility of a potential quarter of patients who may have missed
diagnoses, if relying on FAST scan alone.
6. Discussion There was only one false positive, but in the context of this
patient, as they were haemodynamically stable, the patient went
The high Positive Predictive Value of the FAST Scan combined onto have a CT scan which revealed no free fluid or intra-abdominal
with its high specificity suggests that a positive result in FAST scan injury, allowing the patient to be observed and discharge in due
should be identified and acted upon without delay. However, with course rather than going onto receive therapeutic laparotomy. This
a sensitivity of 46.2% and a ¼ of results being false negative, it is also further showed that within this research, there is an awareness of
prudent to consider carefully what that action should be. FAST’s limitations and if the opportunity arises, more accurate
Early detection of intra-abdominal injury is crucial in allowing imagination is achieved. Due to the fact that small amounts of free
the clinician to optimise the treatment for patients with blunt fluid are, even by experienced practitioners, difficult to detect, or
abdominal injury. CT remains the gold standard investigation for may not be detected by at all by FAST, it has been suggested that if
assessing these patients, however it may not be possible to perform a patient is clinically stable on regular reassessment, a negative FAST
at CT for numerous reasons, some of the most common being scan should be followed up by observation with at least a follow up
haemodynamically instability or pregnancy. FAST scan has clear FAST scan. No trials have been performed regarding this matter.
potential advantages and disadvantages over CT scanning. It is Within the this study, FAST scanning missed 61.5% of solid organ
quick to perform, portable; allowing it to be performed at the injury, again keeping in line with previous studies and experiences
bedside and does not expose patients to radiation. Equally, it is user elsewhere.31 The reason for such low detection rates is explained by
dependant and, as this data suggests, a negative scan does not the fact that a significant proportion of these injuries do not
always rule out an occult pathology, which may later require produce haemoperitoneum, or any free fluid in the abdomen and as
further intervention. such highlight another weakness of FAST. Solid organ injury

Table 2
Table 1
Shows the outcome of FAST scan in all the patients who had therapeutic laparotomy.
Comparative of FAST results with CT/laparotomy finding.
Therapeutic laparotomy
Positive pathology Negative pathology Total
Positive FAST 24 1 25 Positive FAST scan Negative FAST scan
Negative FAST 28 18 46 Number of patients 21 (75%) 7 (25%)
Total 52 19 71 Total 28
ORIGINAL RESEARCH

S. Fleming et al. / International Journal of Surgery 10 (2012) 470e474 473

accounts for a significant proportion of intra-abdominal injury in initial assessment and later imaging and thus cause a bias towards
blunt trauma and even though most are managed conservatively, more false negatives. A similar bias may occur when comparing
the detection of such injury is imperative in allowing the clinician FAST to laparotomy; free fluid may also have developed in the
to make an informed decision as to whether to initiate conserva- interim period between admission and operation.
tive, medical or surgical management. The lack of vital information Another source of possible limitation is interpretation of
in relation to an occult organ injury can be dangerous for the imaging (both FAST and CT) in that there was variability in expe-
patient especially if the injury is significant and causes rapid or rience at the initial reporting, however at the Royal London all CT
sudden deterioration, requiring rapid decisions to be made. This scans were later reviewed by a consultant, whereas by the very
research, in line with the work of Richard et al and McGahan et al, nature FAST scans do not allow for a delayed review and therefore
experienced very low detection rates for renal/adrenal injury as not all of these were consultant scans.
well as a lack of detection of bowel or mesentery injury. This all The other aspect to this possible limitation was that the radi-
gives ammunition to the argument that FAST has no major role in ologist performing both the initial and senior report of the CT
identifying solid organ injury and as such has a major weakness as imaging was aware of the FAST results prior to reviewing the CT
a primary diagnostic choice.32,33 FAST scan is not designed to assess (thus there was no blinding of the image interpreter), however
solid organ injury and if such an injury is suspected, a formal good clinical practise dictates the radiologist should have as much
ultrasound or other imaging modality should be performed by an information as possible, so this is difficult to avoid.
appropriately trained clinician. This study did not use serial FAST examinations. There is evidence
The difficulty in rationalising FAST for haemodynamically to suggest such practise increases the sensitivity of FAST34e36 The
unstable patients is that a negative FAST scan does not rule out exact time of injury was not always documented making it difficult
intra-abdominal injury. Therefore if the patient is unstable, with to estimate time between injury and imaging.
a negative FAST scan, yet there is a high index of suspicion of intra-
abdominal pathology, whether this is based on history, examina- 7. Conclusion and recommendations
tion or a combination of factors, the teams looked at during this
research would proceed to laparotomy regardless of FAST result. This study casts more doubts regarding the usefulness of FAST
The only proviso was that if it was felt that the patient could scan, within practise at the Royal London and thus more widely. The
tolerate it, there was the potential to proceed to CT to give a more high ratio of patients with false negative scans, requiring thera-
informed picture, not only for diagnostic purposes, but to inform peutic laparotomy is a concern. In a trauma centre with an easily
the surgeon of any relevant surgical anatomy. It must be added that accessible CT scanner, this should be the imaging of choice. In
at this time there are no quantitative standards in use regarding unstable patients FAST may help in triaging and identifying
when a patient is ‘stable’ enough to have a CT scan. This again is patients who need to go on to have a laparotomy but other clinical
a clinical decision that was made, as a team, by the clinicians at the considerations play a far more important role in the decision
Royal London. making process and must be carefully examined. Negative FAST
There are, of course, limitations to this study of the experiences scans do not exclude injury to the abdomen and further observa-
at the Royal London. As with all retrospective studies, all data relied tions and imaging are needed to exclude this.
on the written records found in patient notes and so there is the Patients with negative FASTs need further imaging/assessment,
possibility of recall bias, although there was none apparent within however positive FAST scans tell us the patient most likely has
this research. There was as with all retrospective studies no abdominal injuries which may potentially be time critical.
blinding or randomisation, either in those performing or inter- Regarding this study’s effect on the management of patients with
preting any of the imaging or further interventions. blunt abdominal trauma, because we know that a positive FAST
There was exclusion of patients with incomplete data or corresponds with intra-abdominal pathology from CT and lapa-
missing notes, though missing notes and incomplete data sets rotomy findings in 75% of cases, It may help in the triage of patients
were random and occurred in all groups and therefore not to CT in the event of multiply injured patients, although hemody-
believed to cause statistical bias. The quality of FAST scan will vary namic status and patient history are also going to guide our
from one operator to another as the emergency physicians per- decisions.
forming the scans at the time of this study will have had varied In UK trauma centres where CT scanning is available 24 h a day,
amounts of training and experience and there is no data as to the use of FAST scan is limited. Further randomised control trials are
whether every operator has been formally trained or has picked recommended if the role of FAST scanning is to be better under-
up the skill “on the job”. The FAST scans in our study were per- stood. In trauma units it will remain a weapon in their diagnostic
formed by emergency physicians ranging from 1st year Registrars arsenal, but is not the only one at their disposal.
and went on to include staff grades and consultants (depending on
their availability). However a further limitation of the study is that Ethical approval
there is no documentation of the levels of training these doctors None.
received during their careers, prior to performing these scans.
However by ensuring that only senior Emergency doctors per- Funding
formed the scans we guarantee an implicit level of experience and None.
from our data there was no apparent difference in false negatives
between operators of registrar level to consultant. Standardised Author contribution
training that has now been introduced would improve the quality Mr Simon Fleming e Writing the paper.
of any further study. Dr Ruth Bird e Data analysis.
The time taken between FAST scan and CT scan may also have Dr Kumaran Ratnasingham e Data collections.
been another source of potential bias. FAST scan at the Royal Lon- Mr Mike Walsh e Study design.
don was performed within half an hour of patients arriving in the Mr Bijendra Patel e Critically revising the paper.
emergency department and whereas CT occurred at a later stage
(approximately 30e90 min later). There is suggestion that detect- Conflicts of interest
able quantities of free fluid may develop during the time between None.
ORIGINAL RESEARCH

474 S. Fleming et al. / International Journal of Surgery 10 (2012) 470e474

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