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  • G6PD Deficiency Risk Factors

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    Ankit Dua
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    G6PD deficiency is the most common enzyme deficiency worldwide, affecting 400 million people. Most with the deficiency do not require treatment, but should avoid drugs, chemicals, and foods that can cause oxidative stress, including favism from fava beans. The document lists many drugs and chemicals that present high or low risks for oxidative damage in those with G6PD deficiency based on guidelines from the G6PD Deficiency Association.

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    g6pd deficiency risk factors

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    Emedicine.medscape.com-G6PD Deficiency Risk Factors

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    G6PD deficiency is the most common enzyme deficiency worldwide, affecting 400 million people. Most with the deficiency do not require treatment, but should avoid drugs, chemicals, and foods that can cause oxidative stress, including favism from fava beans. The document lists many drugs and chemicals that present high or low risks for oxidative damage in those with G6PD deficiency based on guidelines from the G6PD Deficiency Association.

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    51 visualizações4 páginas

    G6PD Deficiency Risk Factors

    Enviado por

    Ankit Dua
    G6PD deficiency is the most common enzyme deficiency worldwide, affecting 400 million people. Most with the deficiency do not require treatment, but should avoid drugs, chemicals, and foods that can cause oxidative stress, including favism from fava beans. The document lists many drugs and chemicals that present high or low risks for oxidative damage in those with G6PD deficiency based on guidelines from the G6PD Deficiency Association.

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    © All Rights Reserved
    Baixe no formato PDF, TXT ou leia online no Scribd
    Sinalizar o conteúdo como inadequado
    de 4

    G6PD Deficiency Risk Factors

    emedicine.medscape.com/article/2172328-overview

    Glucose-6-phosphatase dehydrogenase (G6PD) deficiency is the most common enzyme


    deficiency in humans, affecting 400 million people worldwide. [1]

    Most individuals with G6PD deficiency do not need treatment. However, they should be
    taught to avoid drugs and chemical exposures that can cause oxidant stress. Patients
    should also avoid broad beans (ie, fava beans). Favism occurs primarily in the
    Mediterranean variety of G6PD deficiency.

    Drugs and foods that present risk in individuals with G6PD deficiency risk factors are
    listed below. They are based on guidelines from the G6PD Deficiency Association. [2]

    The following are considered high risk:

    Acetanilide (acetanilid)

    Acetylphenylhydrazine (2-phynylacetohydrazide)

    Aldesulfone sodium (sulfoxone)

    Arsine

    Beta-naphthol (2-naphthol)

    Brinzolamide

    Chloramphenicol

    Chloroquine

    Ciprofloxacin

    Dapsone (diaphenylsulfone)

    Dimercaprol

    Dorzolamide

    Doxorubicin

    Furazolidone

    Glibenclamide

    Glucosulfone (glucosulfone sodium)

    Isobutyl nitrite

    Menadiol sodium sulfate (vitamin K4 sodium sulfate)

    1/4
    Menadione (menaphthone)

    Menadione sodium bisulfite (vitamin K3 sodium bisulfite)

    Mepacrine (quinacrine)

    Mesalazine - 5-aminosalicylic acid (paraaminosalicylic acid)

    Metamizole

    Methylthioninium chloride (methylene blue)

    Nalidixic acid

    Naphthalene, pure (naphthalin)

    Niridazole

    Nitrofural (nitrofurazone)

    Nitrofurantoin

    O-acetylsalicylic acid (acetylsalicylic acid)

    Oxidase, urate (urate oxidase)

    Pamaquine

    Pentaquine

    Phenacetin (acetophenetidin)

    Phenazopyridine

    Phenylhydrazine

    Primaquine

    Probenecid

    Stibophen (2-(2-oxido-3,5-disulphonatophenoxy)-1,3,2,benzodioxastibole-4-6-
    disulphonate)

    Sulfacetamide

    Sulfadimidine

    Sulfafurazole (sulfisoxazole)

    Sulfamethoxazole

    Sulfanilamide (sulphanilamide)

    Sulfapyridine
    2/4
    Sulfasalazine, salazosulfapyridine (Salazopyrin)

    Thiazolsulfone

    Tolonium chloride, tolonium chloride (toluidine blue)

    Trinitrotoluene (2,4,6-trinitrotoluene)

    The following are considered low risk:

    Aminophenazone (aminopyrine)

    Antazoline (Antistine)

    Arginine (acido 2(S)-ammino-5-guanidilpentanoico)

    Ascorbic acid

    Colchicine

    Diphenhydramine

    Dopamine (L-dopa)

    Isoniazid

    Norfloxacin

    Para-aminobenzoic acid (4-aminobenzoic acid)

    Paracetamol (acetaminophen)

    Phenazone (antipyrine)

    Phenylbutazone

    Phenytoin

    Phytomenadione (vitamin K1)

    Procainamide

    Proguanil (chlorguanidine)

    Pyrimethamine

    Quinidine

    Quinine

    Streptomycin

    Sulfacytine

    3/4
    Sulfadiazine

    Sulfaguanidine

    Sulfamerazine

    Sulfamethoxypyridazine

    Tiaprofenic acid

    Trihexyphenidyl (benzhexol)

    Trimethoprim

    Tripelennamine

    4/4

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