ROCACORBA, LEONARDA (P.R.

Indication MOA Side effect CI

Tranexamic Acid antifibrinolytic agent Tranexamic acid is a -colour vision disturbance - an allergic (hypersensitive)
500mg used to reduce bleeding. synthetic analogue of the -changes in your eyesight reaction to Tranexamic Acid
1 amp+5cc amino acid lysine. It serves
PNSS, intra- -following prostate as an antifibrinolytic by Rare side effects -a blood clot, for example in your
rectal TID surgery reversibly binding four to -a blood clot in your eye leg or lungs
-heavy periods five lysine receptor sites on which may cause bleeding -DIC
-nose bleeds plasminogen (a.k.a plasmin). in the eye, or a loss of vision -pregnancy
-surgery to the cervix in This prevents plasmin itchy, red or swollen skin -kidney failure
women (antiplasmin) from binding (allergic reaction) -fits((convulsion),
-bleeding inside the eye to and degrading fibrin and -History of seizures
-tooth removal in preserves the framework of Very rare side effects -any condition which has caused
haemophiliacs fibrin's matrix structure -allergic reactions which you to have a blood clot or means
-a hereditary disease cause difficulty in breathing that you are at risk of developing
called angioneurotic or dizziness a blood clot.
oedema(HANO) -nausea, sickness or
diarrhoea. Reducing the Warnings and precautions
dose may prevent these Tell your doctor if you have or
symptoms have had:
-a blood clot in your blood kidney disease
vessels (thrombosis) blood in your urine
any uncontrollable bleeding
including menstrual bleeding
Omeprazole Treatment of duodenal
80mg IV/amp ulcers
2amp in 90cc • Prevention of relapse of
PNSS to run for duodenal ulcers
10
• Treatment of gastric
hrs(8mg/hour) ulcers
• Prevention of relapse of
gastric ulcers
• In combination with
appropriate
antibiotics, Helicobacter
pylori (H. pylori) eradication
in peptic ulcer disease
• Treatment of NSAID-
associated gastric and
duodenal ulcers
• Prevention of NSAID-
associated gastric and
duodenal ulcers in patients
at risk
• Treatment of reflux
oesophagitis
• Long-term management
of patients with healed
reflux oesophagitis
• Treatment of symptomatic
gastro-oesophageal reflux
disease
• Treatment of Zollinger-
Ellison syndrome
Omeprazole is a selective
and irreversible proton
pump inhibitor.
-It suppresses stomach acid
secretion by specific
inhibition of the H+/K+-
ATPase system found at the
secretory surface of gastric
parietal cells.
-Because this enzyme system
is regarded as the acid
(proton, or H+) pump within
the gastric mucosa,
omeprazole inhibits the final
step of acid production
The most frequent Hypersensitivity to omeprazole,
significant adverse effects substituted benzimidazoles or to
any of the excipients.
occurring in at least 1% of
patients include: Omeprazole like other proton pump
inhibitors (PPIs) should not be used
concomitantly with nelfinavir
Central nervous system:
headache (7%), dizziness
(2%)
Respiratory: upper
respiratory tract infection
(2%), cough (1%)
Gastrointestinal: abdominal
pain (5%), diarrhea (4%),
nausea (4%), vomiting (3%),
flatulence (3%), acid
regurgitation (2%),
constipation (2%)
Neuromuscular and skeletal:
back pain (1%), weakness
(1%)
Dermatologic: rash (2%)
-Other concerns related to
adverse effects are:
Recurrence of Clostridium
difficile associated diarrhea
Osteoporosis-related
fractures
Hypomagnesemia
Sucralfate This medication is used to Sucralfate is a locally acting Constipation, dry mouth, -High Blood Sugar
1g/tab QID treat and prevent ulcers substance that in an acidic upset stomach, gas, and -Aluminium Poisoning
in the intestines. environment (pH < 4) reacts nausea -chronic kidney disease stage 5
Sucralfate forms a coating with hydrochloric acid in the (failure)
over ulcers, protecting stomach to form a cross- -allergy
the area from further linking, viscous, paste-like
injury. This helps ulcers material capable of acting as
heal more quickly. an acid buffer for as long as
6 to 8 hours after a single
Active duodenal ulcer not dose. It also attaches to
related to NSAID use proteins on the surface of
ulcers, such as albumin and
Maintenance therapy for fibrinogen, to form stable
resolved duodenal ulcers insoluble complexes. These
complexes serve as
Gastro-esophageal reflux protective barriers at the
disease during ulcer surface, preventing
pregnancy—First-line further damage from acid,
drug therapy combined pepsin, and bile. In addition,
with lifestyle and diet sucralfate prevents back
modification diffusion of hydrogen ions,
and adsorbs both pepsin and
Rectal bleeding and its bile acids.
management after
irradiation for uterine
cervical cancer
Feso4 Together with other iron Ferrous sulfate replaces iron Constipation, diarrhea, use/abuse of alcohol, liver
1 tab BID compounds, ferrous stores found in haemoglobin stomach cramps, or upset problems, stomach/intestinal
sulfate is used to fortify in red blood cells, myoglobin stomach problems
foods and to treat and and other heme enzymes in iron overload disorder
prevent iron deficiency the body. Additionally, Iron may cause your stools
anemia ferrous sulfate allows the to turn black
transportation of oxygen via
hemoglobin
Tramadol 50 mg Tramadol is used Action on mu-opioid nausea, dizziness, dry Use of tramadol is not advised for
for 8 hrs primarily to treat mild– receptors mouth, indigestion, people deficient in CYP2D6
severe pain, both acute Also inhibit reuptake of abdominal pain, vertigo, enzymes
and chronic norepinephrine and vomiting, constipation, It is not recommended in those
epinephrine drowsiness and headache. who are at risk of suicide
While not recommended in
women who are breastfeeding,
those who take a single dose
should not generally stop
breastfeeding.