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BioMajesty
Course Material
Version 3
INDEX
1
BASIC OPERATION 5
ROUTINE OPERATION ...................... 1-1 ISE UNIT
BASIC STEPS FOR ROUTINE OVERVIEW ......................................... 5-1
OPERATION (FLOW CHART) ........ 1-19 ANALISYS OPERATION ................... 5-1
ORDER ENTRY ................................. 1-20 ROUTINE OPERATION AND
AUTO SYSTEM AUTO SYSTEM CALIBRATION.................................... 5-1
STARTUP/SHATDOWN..................... 1-22 SETTINGS ........................................... 5-5
MAINTENANCE ................................. 5-8
2 ISE UNIT LAYOUT ........................... 5-15
DATA ISE MODULE SCHEMATIC
RERUN SAMPLES .............................. 2-1 DIAGRAM ......................................... 5-15
REACTION PROCESS......................... 2-7
REALTIME MONITOR 6
(STANDARD OUTPUT FORMAT) .. 2-10 USER INTERFACE
FLAGS FOR CALIBRATION AND SYSTEM .............................................. 6-1
CONTROL DATA .............................. 2-11 OPERATION PANEL WINDOW .......... 6-3
ALARM FLAGS ................................ 2-13 MENU WINDOW ................................ 6-9
REQUEST .......................................... 6-9
3 CALIBRATION................................ 6-22
SETTINGS QUALITY CONTROL...................... 6-27
VARIOUS SETTINGS.......................... 3-1 REGENT .......................................... 6-33
NEW REGISTRATION ...................... 3-17 MAINTENANCE ............................. 6-37
SETUP ............................................. 6-46
4 7
MAINTENANCE OTHERS MATERIALS
MAINTENANCE CHECKLIST........... 4-1 HbA1c .................................................. 7-1
BEFORE STARTING OPERATION...... 4-4 NEW SAMPLE CONTAINER
DAILY AND WEEKLY WASH ............. 4-8 SETTING ............................................. 7-7
REGULAR MAINTENANCE............. 4-10 ALARM TABLES .............................. 7-10
REGULAR PARTS DETARGENT DESCRIPTION ........... 7-26
REPLACEMENT................................ 4-25
OTHER MAINTENANCE .................. 4-27
FOOTER I-1
BASIC OPERATION
1
1.1 ROUTINE OPERATION ................................................................................... 1-1
1.1.1 STARTUP PROCEDURE .......................................................................... 1-1
1.1.1a Turning on the main power switch on the Analyzer unit. ................... 1-1
1.1.1b Starting the Water Supply Unit ........................................................... 1-1
1.1.1c Setting the Main Power on the Analyzer to PC CONTROL............... 1-1
1.1.1d Turning On the Main Power on the Workstation................................. 1-2
1.1.1e Starting Up the Workstation................................................................ 1-2
1.1.1f Setting the Analyzer Unit to READY ................................................. 1-3
1.1.2 PREPARATION ......................................................................................... 1-3
1.1.2a Completing the Checklist before Startup ............................................ 1-3
1.1.2b Adding Reagents and Detergent.......................................................... 1-4
1.1.2c Prime ................................................................................................... 1-5
1.1.2d Startup Wash ....................................................................................... 1-5
1.1.3 ANALYSIS................................................................................................. 1-6
1.1.3a Calibration and Quality Control.......................................................... 1-6
1.1.3b Analyzing an Patient Sample .............................................................. 1-9
1.1.3c Adding samples and interrupting analysis with a priority sample .... 1-12
1.1.3d Check the data and the status of analysis. ......................................... 1-15
1.1.4 SHUTTING DOWN THE ANALYZER.................................................. 1-17
1.1.4a Shut Down Wash ............................................................................... 1-17
1.1.4b System Exit ....................................................................................... 1-17
1.1.4c Shutting down the Workstation and the Analyzer unit...................... 1-18
1.1.4d Turning off the Water Supply Unit. ................................................... 1-18
1.2 BASIC STEPS FOR ROUTINE OPERATION (FLOW CHART)................... 1-19
1.3 ORDER ENTRY............................................................................................... 1-20
1.3.1 Steps to start analysis per cup position..................................................... 1-20
1.3.2 Using Batch Entry to register samples ..................................................... 1-21
1.4 AUTO SYSTEM STARTUP/SHATDOWN ..................................................... 1-22
1.4.1 Standard Operation................................................................................... 1-22
1.4.1a Check the settings ............................................................................. 1-22
1.4.1b Executing Automatic Startup from Auto Shutdown.......................... 1-23
1.4.1c Standing by for auto-startup.............................................................. 1-24
1.4.1d Completing Auto Startup procedure.................................................. 1-24
1.4.2 Other Functions ........................................................................................ 1-25
1 BASIC OPERATION
Power panel
Analyzer Workstation
Power panel
1-1
1 BASIC OPERATION
• Re-Start: The date that the system was previously started is displayed in System
Date. The ordered tests and data for that day are maintained when the
system starts up. You can resume the existing work orders and analyses.
2. Click OK.
Click OK to start the workstation and turn on the switch on the Analyzer. The Menu
Window and the Operation Panel Window appear (refer to the screenshot below).
1-2
1 BASIC OPERATION
The operation mode display in the Operation Panel Window changes from
SYSTEM INIT to WAIT.
Enter the user name and the password if you set in User Code Settings.
If you leave the system power on overnight and want to change the system date to
today’s date, perform the shutdown operation described in P 1-17, 1.1.4b. Check
that the today’s date appears in System Date in the BioMajesty Startup Window,
then select New Start.
Through initialization, the unit returns to its original state and after about 1 minute, it is
ready for use. The operation mode display in the Operation Panel Window changes
from WAIT to INITIALIZE and when initializing is completed, it changes to READY.
On the Power Panel of the analyzer, only ‘READY’ display is turned on.
After successfully completing an operation, the analyzer mode returns to
READY (except when connected to a rack handler or LAS). When the ana-
lyzer is in READY mode, no units are in operation, therefore, it is safe to per-
form some maintenance work that is allowed with the analyzer power on or re-
plenish the reagents. (You can also replenish the reagents when the analyzer is
in WAIT mode.)
If a problem occurs while starting the system, an alarm goes off and a message
appears in the Operation Panel Window. The operations are stopped and the
red light of ALARM on the Power Panel is turned on. After fixing the prob-
lem, click INITIALIZE again to set the analyzer mode to READY. Click the
ALARM button in the Operation Panel Window to clear the message and
open the Error Report window to check the details of the error (see P 6-43
10.Error Report and 7-10 Alarm Table).
1.1.2 PREPARATION
1.1.2a Completing the Checklist before Startup
See P4-4 Before starting operation
1-3
1 BASIC OPERATION
Daily and weekly cleaning methods differ depending on the type of analysis. Please ask
your local service agent for details.
As the hypochlorous acid soda in REAGENT PROBE WASH-S is easily decom-
posed, make 5% solution every time before use. Set the 5% solution of PROBE
WASH to RTT just before use and remove it immediately when the wash is com-
pleted.
Prepare the ISE Detergent Solution every time before use and change it every day.
1-4
1 BASIC OPERATION
1.1.2c Prime
If the analyzer is left unused overnight or for a long period of time, air bubbles may be
formed in the lines of the sampling pump, reagent pumps, and wash pump. Remove any
air bubbles by performing Prime.
1. Click PRIME in the Operation Panel Window.
1-5
1 BASIC OPERATION
1.1.3 ANALYSIS
1.1.3a Calibration and Quality Control
Follow the instructions below to measure the reagent blank, calibrator for
standard measurement, and control serum for cumulative QC.
② Start measurement.
a. Click START in the Operation Panel Window.
The Start Condition dialog box appears.
1-6
1 BASIC OPERATION
Temp.test select
d. Click Analyze for Control smp. under Control.
e. Click Start.
Analysis starts and data is acquired.
You can check the progress of the analysis in Test Result Monitor in Request list
(see P 1-15).
The analysis results are displayed in Real Time Monitor in Request list (see P
1-15).
Patient sample can be started at the same time as other samples. However, it cannot
be started at the same time when multipoint calibration is selected. (Patient sample
and calibrator for multiple calibration use different STT numbers)
1-7
1 BASIC OPERATION
click OK (selected control names are highlighted in blue). Use this opera-
tion to register the current day’s average data and fluctuation range in the
QC Cumulative dialog box. (If you do further analysis of the control sample
after that, open the Daily Precision Control dialog box again and after
checking the data, repeat the same procedure as above and overwrite the
average value and fluctuation range in the QC Cumulative dialog box. see
P6-29)
⑤ Recalibration
If the result data is poor, find the cause, solve the problem, and start again from step
2 listed above. After selecting Analyze under Calibration in the Start Conditions
dialog box, configure the necessary options for recalibration in Temp. test select.
Repeat the same procedure for Control and click Start. (It is also possible to select
Special calib. and configure the tests for recalibration.)
Be sure to always check the precision control data of the recalibrated test and
delete data as necessary by using Omit function (see P 6-29). (Data cannot be
modified.)
1-8
1 BASIC OPERATION
2. Start measurement
Barcode Analysis
a. Click START in the Operation Panel Window. The Start Condition dialog
box appears.
1-9
1 BASIC OPERATION
Barcode No.
e. Click OK.
Analysis starts and the data is acquired.
You can set the timer to automatically start analysis when the barcode reading is
completed. Configure its setting in 34. Sample Barcode Confirm Time in Set-
ting System Parameters in Setup (see P 6-61). The set time (in seconds) is dis-
played in Starting in in the upper right corner of Sample Confirmation dialog box.
The analysis begins when this timer reaches zero.
To fix barcode read errors, see P 6-5.
1-10
1 BASIC OPERATION
When a rack handler or LAS (Laboratory Automation System) analysis is started, the
analyzer’s mode continuously changes among START, HOLD, and WAIT. Sam-
ples must be added from the rack handler or LAS during this time. If you need to
add samples directly to the Sample Tray, always follow the procedure 3-2 described
below. After the additional samples are aspirated on the Sample Tray, the analyzer
automatically returns to the rack handler or LAS analysis. However, the analyzer
mode does not automatically go to READY when the analysis from rack handler and
LAS is selected in Start Conditions. To return to READY mode, press STOP.
1-11
1 BASIC OPERATION
Check the SMP LOAD OK (Append) indicator in the Operation Panel Win-
dow before changing the samples. Follow the step 2 “Start measurement”
listed above to start the analysis after changing the samples.
b. Check that the analyzer is displaying SMP LOAD NG(Append) (when the
rack and LAS are online, the analyzer displays SMP LOAD OK(Append)),
then place the sample in the Sample Tray. Follow the step 2 “Start meas-
urement” listed above to continue the analysis.
When the analyzer is in START mode, HOLD mode, or WATCH mode,
PAUSE or STOP button can be selected. If STOP is selected, SPP stops as-
pirating new samples and the analyzer goes to STOP mode. The analyzer can
be restarted at this point. If you do not restart the analyzer, it changes from
END mode to READY mode.
1-12
1 BASIC OPERATION
② Using the SmartPAUSE function (this can only be used during barcode analy-
sis).
This function cannot be used during analysis by cup positions and multipoint
calibration measurement. Do not open the Sample Tray cover in these situa-
tions.
a. Open the Sample Tray cover.
The Shift to PAUSE・STT impossible to remove(Add impossible) dialog box ap-
pears.
Do not close the Sample Tray cover when the Shift to PAUSE・STT impossible
to remove(Add impossible) dialog box is displayed.
b. When the analyzer changes to Smart PAUSE mode, place the sample and
close the Sample Tray cover.
c. The analyzer automatically starts reading all the barcodes of the STT and
the Sample Confirmation dialog box appears. Check the displayed sample
IDs and make changes as necessary. Put check marks to the samples that
need to be processed as priority samples. (see P 1-10)
Smart PAUSE function can be used only during the barcode analysis. Also, fol-
lowing settings must be configured before using Smart PAUSE:
Select Setup in Menu. From the Setup list, select System Specification Settings.
(see P6-46)
In the System Specification Set dialog box, select as follows:
Under System Basic Configuration, select Avail. for Sample Barcode.
Under Basic System Operation Mode, select Rerun tests or Incomplete tests for
Rerun Flag.
Under Smart Pause, select Avail for STT Cover.
1-13
1 BASIC OPERATION
d. Check the sample ID and click Start to start the analysis of the STAT sample.
The analysis is started automatically when the set time has passed. The
default setting of the timer is 15 seconds.
You can check and change the timer settings in Setup–Setting System Pa-
rameters–39:STAT Port Request Screen Timer (see P 6-61).
e. STAT Port dialog box will close when the aspiration of the STAT sample is
completed. When the STAT lamp on the analyzer changes back to green,
you can pull the lever to take the port out and set a next STAT sample.
If you are going to measure barcode samples with STAT, you need to configure
Avail. in advance in Setup–System Specification Set–STAT Port Barcode (see
P6-46).
When you are setting a sample with no barcode for STAT analysis or when the
STAT Port Barcode setting in System Specification Set is N.A., workorders can
be selected in STAT Port dialog box under STAT Set Specification (Configure it
in advance in Request–STAT Order Setup (see P 3-2)). The samples ID incre-
ment from S01 to S100. You can change the Container Type and Order Test by
clicking the Temporary Change button (see P 6-6).
1-14
1 BASIC OPERATION
The latest data are displayed in Test Result Information. The remaining analysis time
and finish time will be displayed when you double click on the sample positions. Click
Analyzing Sample Info. button to display the status of samples being analyzed from the
rack handler or LAS.
1-15
1 BASIC OPERATION
You can specify the range of data to print by clicking Print. (There are 2 types of displays
and print formats.) You can change them in Maint–System Monitor (see P 3-12).
1-16
1 BASIC OPERATION
① Click System—Exit.
② Click Yes.
The exit confirmation window appears again.
1-17
1 BASIC OPERATION
③ Click Yes.
1-18
1 BASIC OPERATION
Start Up Analyze
OK Calibration
Run single point calibration and multip
INITIALIZE point calibration Temporary change f
Auto Startup
* Patient Sample*
Analyze (Set the samples)
START
1
- Barcode analysis
Completion START
(After reading the barcodes)
Confirmation
WASH 2
Use REAGENT PROBE WASH-K once a week (After entering work orders)
2
Auto Shutdown
Enter password(manager)
1-19
1 BASIC OPERATION
If you use the same number for Order no., Posi no., and Samp. no. on the same day,
the data of workorder that is already registered is displayed in the fields. If you
click the Enter button, a message dialog box is displayed to prompt if you want to
1-20
1 BASIC OPERATION
overwrite the data. If you do not want to overwrite the data, click New and enter
the workorder from step 1).
• Enter Samp. type, Dil. factor, and Comment, if required.
• Note that Container type, Samp. type, Dil. factor and Sex remains the same on the
display once they are changed and registered in a workorder. These information do
not automatically go back to the default settings.
• If you have set a group of tests in Profile set in Profiles, you can select tests in the
registered set of tests by clicking one test name. Click the Create Profile button to
create a set of tests.
• To review the registered samples, click the View worklist button, select all and click
OK. You can check the sample volume required for the workorders.
1-21
1 BASIC OPERATION
1-22
1 BASIC OPERATION
• Example: Select Proc. Set to ‘Set1’ to combine the Auto Shutdown with Auto
Startup. Set System p.s. to ‘Power off’ and System end to ‘System end’.
Set WASH2 and End ISE operation as required.
If combining Auto startup and Auto Shutdown, do not select Shutdown or
Nothing in System End. If System end is set to Shutdown, the system cancels
the Auto startup during the shutdown process. If Nothing is selected, the
computer remains turned ON and Auto startup does not take place.
Fig. 2
If you configure the Shutdown settings as up to the step (6) above while the analyzer
is in a mode other than READY, Start is will be displayed in Time remaining to
indicate that the Shutdown process is pending. The Shutdown process automatically
1-23
1 BASIC OPERATION
starts when the analyzer mode changes to READY. Click Cancel to cancel the
pending Shutdown process.
If you want to stop the Auto Startup process after it has begun, click Stop in the top
left-hand corner of the System Startup/Shutdown Setting dialog box. When the
current step is completed, the Auto Startup process stops.
If you need to cancel Auto Startup after On button under Enable auto start is se-
lected, click Off and ensure that the Start field is blank. If the System
Startup/Shutdown Setting dialog box is closed without selecting Off, the Auto
Startup is still on.
To cancel auto startup, click Cancel in the above dialog box and the BioMajesty
startup window will appear. If you cancel Auto Startup as soon as the analyzer
starts up, it takes about 5 minutes for the BioMajesty startup window to appear.
Check that New start or Re-start has been selected and click OK to perform the
normal startup procedure. (Click the OK button to activate the analyzer from Sleep
Mode.)
1-24
1 BASIC OPERATION
① Select Startup in Mode Set and configure the PRIME, WASH, and Cuvette
Blank processes in Set 1 to 3.
② Ensure Startup under Select wash routine is selected, select the Proc. Set.
and click Yes to execute it.
When all the settings in Startup process set are completed, the analyzer returns to
READY mode.
1-25
2 DATA
2.1 RERUN SAMPLES............................................................................................ 2-1
2.1.1 Checking data ............................................................................................. 2-1
2.1.2 Checking reaction process.......................................................................... 2-1
2.1.3 Checking reanalysis conditions .................................................................. 2-2
2.1.3a Flag settings ........................................................................................ 2-3
2.1.3b Setting reanalysis conditions............................................................... 2-4
2.1.3c Confirming reanalysis conditions........................................................ 2-4
2.1.4 Automatic rerun.......................................................................................... 2-5
2.1.4a Rerun settings...................................................................................... 2-5
2.1.4b Reruns ................................................................................................. 2-6
2.1.5 Rerun data................................................................................................... 2-6
2.2 REACTION PROCESS...................................................................................... 2-7
2.3 REALTIME MONITOR (STANDARD FORMAT)......................................... 2-10
2.4 FLAGS FOR CALIBRATION AND CONTROL DATA................................. 2-11
2.4.1 Calibration ................................................................................................ 2-11
2.4.2 Precision control....................................................................................... 2-12
2.5 ALARM FLAGS .............................................................................................. 2-13
2 DATA
Review/Edit
The samples with yellow icons in the Order # column or asterisks (*) in the R column
have rerun flags. If you click the order number, the ordered test and information on the
measured data appear in the middle of the window. The tests with check marks (√) dis-
played in the R checkboxes will be rerun.
① Go to Reaction Monitor window (the figure below). Select Sample Type and en-
ter necessary information such as a sample number in Sample list.
2-1
2 DATA
② Select a test name from the Test name list to display the reaction process (the
curve displayed in green). Detailed data of the reaction process is displayed in
React.proc.data box.
③ Check Approx.curve box to display detection points on the reaction process curve.
Check M/S-WL box to display main wavelength in red and sub wavelength in blue
on the curve.
④ Check the reaction process.
The following example shows the reaction process when AMY is 10926 IU/L and data is
flagged “H”, “u”, and “n”.
Reaction Monitor
2-2
2 DATA
In the initial analysis (M), if the data are outside the range from Abnormal value
(L1) to Abnormal value (H1), the analyzer posts “H” or “L” flags to the result.
For the reruns (using Dilute1 (D1)), if the data are outside the range from Abnor-
mal value (L2) to Abnormal value (H2), the analyzer posts “H” or “L” flags to the
result. (The settings for Dilute 2 to Dilute 4 are for immunoassay tests.)
2-3
2 DATA
In this example, if the data are flagged “H” (Abnormal value (H): 1 in the above dialog
box), the test will be rerun using conditions D1.
(If you specify multiple rerun conditions to one flag, the test will be rerun using all se-
lected conditions. If data has multiple flags, the test will be rerun using all conditions
selected for each flag.)
2-4
2 DATA
Reanalysis conditions
When you are using multiple dilution conditions, set them in the order of low dilu-
tion ratio to high dilution ratio: from Dilute 1 (D1) to Dilute 4 (D4).
If you set the conditions as discussed in setps (a) to (c), the selected reanalysis conditions
will appear in Dil.cond box in Review/Edit screen (P 2-1) when the result data is flagged.
You can start reruns immediately or you can change the Dil. Cond, save it, and start re-
analysis.
2-5
2 DATA
Auto.retest
• N.A.: The analyzer does not start the rerun automatically. You need to start it
manually. The analyzer performs the rerun according to Rerun Flag. Settings.
• STT Retest: When the rerun is ordered, the analyzer automatically dispenses the
sample from STT and dilutes it according to the rerun conditions (settings in the Re-
analysis conditions dialog box), and then analyzes it. You cannot remove the sample
from the analyzer until dispensing has been completed. (SMP load NG)
Rerun Flag (When N.A. is selected for Auto.retest)
• Rerun tests: After the analyzer runs all tests, it reruns the tests with no result values
and the tests with rerun ordered. .
• Incomplete tests: After the analyzer runs all tests, it reruns the tests with no result
values.
• All tests: After the analyzer runs all tests, it reruns all tests.
The settings you have changed in the System Specifications Set window take effect
after you click the Save button and perform New Start in the BioMajesty startup
window. (Refer to P 6-46.)
2.1.4b Reruns
If you select N.A. for Auto.retest as shown in the example, you need to start the analysis
manually.
If the computer is connected to the host computer system, check in advance how the
host computer handles the rerun data.
In the example analysis result shown above, the information on the data is as fol-
lows:
Sample vol of AMY: 1.3 μL
Concentration at the initial run: 10926 IU/L
Flag: H, u, n
(The absorbance is greater than the value set for Abnormal value (H1) and the
number of data points used for calculation is only four.)
For the rerun data that were analyzed using the D1 conditions, if the data is greater
than or equal to the value set in the H2 box for Dilute 1 (D1) in the Abnormal
value setting dialog box (refer to P 2-3), the analyzer flags the data “H.” If the
data is less than or equal to the H2 setting, the analyzer flags the data “L.”
2-6
2 DATA
Sub
w av elength
694nm
R2
OD Five min
1.0
Main
wavelength
340nm
Blank (d)
Detection
6–10 min
The system calculates the concentration using the mean of the changes in OD per minute that
is calculated using all the data from M-DET.P.m to M-DET.P.n. The system performs the
blank correction for the mean value before calculating the concentration.
2-7
2 DATA
Blank (d)
Since the OD of the
sample is greater (darker)
than the OD of the reagent
blank, the system adds the M ain
difference between the two w avelength
OD values to sample (d).
340nm
Detection
Sample (d) 6–10 min
Sub
wavelength
The system does not use the detection points whose OD values are less than sample (d) (in a
decreasing reaction) or are greater than sample (u) (in an increasing reaction). If the number
of detection points in the range from DET.P.m to DET.P.n is five or less, the system goes back to
find a total of six detection points for the calculation, but does not use the data beyond the point
DET.P.l. If the number of detection points is five or less, the system flags the data “d” (in a
decreasing reaction) or flags the data “u” (in an increasing reaction).
Main
wavelength
Example: When the activity is high (in increasing reactions) 410nm
Detection
6–10 min
Sample (u)
Since the system has
only three data
OD points it can use for
the calculation even
1.0 if the system goes
back to find data, the
system flags the data
“u.”
Sub
Reagent blank wavelength
505nm
E2 M-DET.P.l M-DET.P.m M-DET.P.n
Mean OD at detection points 4 and 5 25 27 42
2-8
2 DATA
Prozone check
The following example of setting M-DET.P and S-DET.P is for checking prozone. These are different
settings from those for calculating OD.
Example 1 Rate assay: As the following figure shows, the system compares both variations
from M-DET.P.m to M-DET.P.n and from S-DET.P.p to S-DET.P.r. (Apr and
Amn are variations.) If the difference between the two variations is big, the
system judges that the data is in the prozone and flags the data “P.”
Apr Amn
0.8
OD
Example 2 Prozone formula: If the calculated value Amn/Apr − K × Apr is greater than or
equal to Prozone limit, the system judges that the data is in the prozone
and flags the data “P.” The value K is automatically calculated when the
system performs the liquid volume correction. (Prozone judgment: upper
limit) (Refer to the right figure below.) At this time, the system performs
the liquid volume correction for the OD value at S-DET.P.r.
However, since S-DET.P.p and S-DET.P.r are usually zero, the system judges it
using the median of the data between M-DET.P.m and M-DET.P.n. (Prozone
judgment: upper limit) (Refer to the left figure below.)
Amn
2
Amn
OD Prozone limit value 0.8 Abnormal sample
Apr
OD
Adding antigens
and so on
Normal sample
M-DET.P.m n S-DET.P.p r M-DET.P.m n
27 29 17 19 40 42
2-9
2 DATA
検体番号
Samp.no 位置番号 コメ ント 1コメ ント
Comment 性別 年齢 検体種別
Samp.type 希釈係数
Dil.factor 採血日
Positionnumber
Position number Comment1 Comment
Comment22 Sex Age
Date of taking blood
Flag
Samp.no Sample ID number is displayed. Below is the example how some IDs are
displayed.
Patient samples: ID number from sample barcodes or manually entered ID
number
One-point calibration: ‘C’ for calibration, CTT position number, number of
analyses (e.g. C0101).
Multipoint calibration: ‘M’ for multipoint, turn table number, position num-
ber, number of analyses (e.g. M980101)
Control: type of control, number of analyses (e.g. PA001)
Conc. Measured values appear for control samples and routine samples.
For reagent blanks, the value 0 appears. The FVs appear for the standard
samples.
Flag If the data have flags, they appear in this column.
ABS-RB The calculated absorbance from which the reagent blank has been sub-
tracted.
ABS ABS is the result of ABS1 – ABS2, where ABS2 is corrected for the liquid
volume. (In RRA, the changes in OD are used for calculating absorbances.
In EPA, the OD values are used for calculating absorbances.)
For the reagent blank, the OD values of the measured reagent blank appear.
E1 In RRA, if you specified Check D.P., the OD value at the main wavelength
appears. Otherwise, the OD value at the main wavelength at M-DET.P.m
appears.
In EPA, the OD values at the main wavelength at M-DET.P.m appear.
E2 E2 data (the mean of the 4th and 5th detection points), which is the OD value
at the main wavelength.
ABS1 The calculated value at M-DET.P (OD value)
ABS2 The calculated value at S-DET.P (OD value)
N Number of data points used for calculation
S The dispersion of absorbances used for calculation, expressed as a percent-
age of absorbances.
P The calculated value of prozone check
RRV Number of the reaction cuvettes used
2-10
2 DATA
• Example: ALB
Reagent blank (ABS) 0.05575
Standard (ABS-RB) 0.11501
You can check the values in the Calibration Summary dialog box.
Go to Calib. and select Veiw Calibration Curve. Click Calib. Summary button.
For the tests of the reaction rate assay (RRA analysis method), if the data are outside of the
range defined by Blank (u) and Blank (d) in the Analytical Parameters (Chemistry) window,
the analyzer flags data “U” or “D”. Go to Setup to open Analytical Parameters (Chemis-
try) window.
Reaction Monitor
Go to Setup and select Analytical Parameters (Chemitry) to open Error judge rate (vs.
previous data). (see P6-47) In this dialog box, set the acceptable value (%) for the difference
between the current calibration data set and the previous one. If the difference is greater than
2-11
2 DATA
H
3 × Standard deviation (3SD)
h 2 × Standard deviation (2SD)
2-12
2 DATA
2-13
2 DATA
M Mix Error The rotation and reciprocation movement of the mixing rod
(uppercase) is less than the specified number of times
Q Liquid level sen- Air is aspirated while aspirating sample from SPP
(uppercase) sor error
G Crash The edge of the probe has collided with something when
(uppercase) SPP was descending.
If a crash occurs, the analyzer mode changes to WAIT.
Z Abnormal cali- The difference between the currently measured calibration
(uppercase) bration data ABSs and the previously measured one is outside the ac-
ceptable range.
Acceptable range (%) < | previous ABS – new ABS | / previous
ABS × 100 (%)
Refer to the instruction manual for the details.
2-14
3
SETTINGS
3.1 VARIOUS SETTINGS....................................................................................... 3-1
3.1.1 STAT Sample Operation and Sample Container Settings .......................... 3-1
3.1.1a Priority settings ................................................................................... 3-1
3.1.1b Setting the container shape.................................................................. 3-1
3.1.2 STAT Order Setup ...................................................................................... 3-2
3.1.3 Reagent PAUSE .......................................................................................... 3-2
3.1.4 Reagent ....................................................................................................... 3-3
3.1.4a Check the remaining amount of reagent in Reagent — Reagent
Test Monitor. ....................................................................................... 3-3
3.1.4b If the reagent becomes empty during analysis without using the
settings from the Auto Reagent PAUSE function ................................ 3-4
3.1.5 Change of Reagent Bottle Size................................................................... 3-4
3.1.6 Change of Reagent Bottle Position............................................................. 3-5
3.1.7 Reagent Barcode Setting ............................................................................ 3-5
3.1.8 Change of STD........................................................................................... 3-6
3.1.8a One-Point Calibration Curve............................................................... 3-6
3.1.8b Multi Standard..................................................................................... 3-6
3.1.9 Change of Calibration Curve...................................................................... 3-7
3.1.10 QC Sample Definition ................................................................................ 3-8
3.1.11 Control Data Registration......................................................................... 3-10
3.1.12 Changing RealTime Monitor Window Display (Same as in Batch
Print)......................................................................................................... 3-12
3.1.13 Batch Print................................................................................................ 3-13
3.1.14 Save of Text File....................................................................................... 3-13
3.1.15 Screen Print .............................................................................................. 3-13
3.1.16 Setting of Analytical Parameters (Serum) ................................................ 3-14
3.2 NEW REGISTRATION ................................................................................... 3-17
3.2.1 New Test Registration (Chemistry) .......................................................... 3-17
3.2.2 New Test Registration (Ratio)................................................................... 3-21
3 SETTINGS
The Setup menu is added to the menu window, and the window where you can change the
settings is added to the menu. By opening the window, you can perform confirmations,
entries, and changes to the settings. In order not to open the window (return to the original
state), enter “user” in the same place.
3-1
3 SETTINGS
3-2
3 SETTINGS
② The RTT position number without enough reagent turns red and is automati-
cally displayed with a check flag. Check for other tests to scan for remaining
levels. (The RTT position of the test, in which its number of remaining test
times falls below the setting, turns yellow.)
The bottle position of a test using a reagent barcode is not checked automatically. Be
sure to check to see if the test is checked if the reagent returns to the same position
after refill or replacement.
3.1.4 Reagent
3.1.4a Check the remaining amount of reagent in Reagent — Reagent Test
Monitor.
• For each test, the number of remaining test times, RTTNo. and Remain vol.(ml) of the
first to third reagents are displayed. (If several reagents are set for the same test, * is
placed in the top number displayed.)
• When the number of remaining test times falls below 100, the test name and graph are
displayed in yellow (You can change the set value for each test in Remain Test.)
• If the reagent becomes empty in Test Name, the test name appears in red and an E ap-
pears for the test number.
3-3
3 SETTINGS
• The test name appears on a button. The number of remaining test times and the reagent
position appear for the R1 or R2e reagent. (see P6-34)
3.1.4b If the reagent becomes empty during analysis without using the set-
tings from the Auto Reagent PAUSE function
An alarm sounds, and a message appears in the window. Only that test is processed as un-
finished, while the other analyses are continued. Click the ALARM button to open the
Error Report window in which you can check Sample no. and Test name (See P 6-43).
In the START mode,
click the R-PAUSE button in the operation panel to change the analyzer from
R-PAUSE SHIFT mode to R-PAUSE mode, and perform the operation in P 3-2.
In the STOP mode, the R-PAUSE button does not function.
Wait till the analysis is finished and the analyzer enters the READY mode. Then,
open the Reagent – Reagent Test Monitor window and click Reagent Scan. When
the Reagent Bottle Scan window appears, perform the same operation as P 3-2. The
analyzer enters the READY mode after scanning. Perform the START operation to
resume analysis.
In the READY mode, select Specif.no.
or All using the Reset button in Re-
agent – Reagent Test Monitor, and
click OK to reset the remaining level
of the reagent (Full display). You can
perform the measurement without
scanning.
(After that, if RPP aspirates the reagent
during measurement, the display for the re-
maining level changes.)
3-4
3 SETTINGS
If you want to install two or more reagents of the same test, enter multiple numbers in
the position column. In case of installing reagents in positions 1 and 2, enter 1, 2. In the
case of installing in positions 1 to 3, enter 1- 3. The reagents are used in order, starting
from the smallest position number, and if they are used up, the reagent bottle with the
subsequent number is used.
3-5
3 SETTINGS
3-6
3 SETTINGS
• Enter the concentration change in the Coeff(FV) column of each sample, Return, and
Save it.
• Enter the changes for the Blank position or STD position in the column of each sample,
Return, and Save it. If the position has been changed, click the STT Setting button to
check and change Container, Meas.times, and comments on that position number.
3-7
3 SETTINGS
① Click A (or unset control ID) in Ctrl.ID of QC Sample Definition and click Test
name from Test table.
② Set the CTT position number to place a control during measurement in CTT
Posi.no.
③ Enter the control name in Comment 1, the lot number and other information
in Lot.No./Data.
(This comment appears in RealTime Monitor or in print.)
④ Usually, set 1 in Dil.factor, and set Samp.type, Container, and Replicates.
For setting the control serum for urine, set Samp.type to Urine.
⑤ Click the CTT Set button to check the position of the Container and Reps.
and enter the control name and other information in the comment column.
(This comment appears in the Sample Select or CTT Set window.)
3-8
3 SETTINGS
⑥ Click the Return button to close the CTT Set window and click Save in the
QC Sample Definition window to register it. (The definition will not be saved
if selecting the Cancel button.)
⑦ In order to set the subsequent control sample, click B in Ctrl.ID, select the
test, and make the settings as in ②.
3.1.10b Click the CTT position set in 1 above in QC — Sample Select to register the
CTT position. ( See P6-24)
3.1.10c Click the measurement test in 2.Ordinary control samp.meas in QC — Test
Select to register the measurement test. (See P6-16.)
3.1.10d Register control values in QC — Control Data Registration.
• If control serum has been newly registered, enter Mean and SD in Daily QC and QC
Cumulative for each control.
• If the reagent or control sample has been changed, the control value also changes and a
value shifts on the graph for precision control. You can change the control value ac-
cordingly.
3.1.10e Select the test to be displayed in the Daily Precision Control and QC Cu-
mulative windows in order to reflect the data of selected test.
① Click the Display order test button in QC — Daily Precision Control.
② Select the test from the Meas.Test column to turn it blue, click ≫ to move
it to the Select Test column, and click OK. (The test in the Select Test column
appears.)
3-9
3 SETTINGS
• Change the window display from X-Chart to Control Data and check or delete
the data. (For deleting the data, see P6-28 Omit operation, User Interface). Be sure
to click Save after deletion.
3-10
3 SETTINGS
③ Change the window display to QC List and check the average values and
standard deviations.
④ In order to employ this data as a control value, click the Save control data
button. Select the test to be stored in the Save control data — Test select
window and click OK.
⑤ Check that the test has been copied to the QC Cumulative column of that
control in QC — Control Data Registration. (Click the Copy button as nec-
essary, to copy the test to Daily QC. The Copy button copies the control val-
ues of all the controls at the same time.)
3-11
3 SETTINGS
Standard
Simplified (concentration)
You can set the word size (big or small) for the Request – RealTime Monitor display (P
1-15).
3-12
3 SETTINGS
3-13
3 SETTINGS
• Request.test range・・・In order to optimize the Analyzer’s throughput, serum indices are
calculated only when the serum indices are already required in a test
in the workorder for the sample.
• Compulsory test analysis・・・Serum indices for all of the samples are calculated. If the
settings for serum indices are already required in a test in the wor
korder for the sample, it will be measured as per the settings. If not,
the analyzer refers to the test set in No1 in Analytical Parameters
(Serum) window and automatically generates a workorder as set in
No1 to calculate the serum indices.
3.1.16b Register the analytical conditions of the test for the serum index measure-
ment.
In the case of setting Compulsory test analysis in 1 above, if the sample request does not
include a test available for serum index measurement, a request is automatically generated
for a test available in the setting No1. In order to avoid this, set a new test for the serum in-
dex measurement.
See 1. New Test Registration (Chemistry), P 3-17.
① Setup — Analytical Parameters (Chemistry) (Password: manager)
Enter R1=100 ㎕ , R2=0 ㎕ , SV=2 ㎕ , reaction time = 3minutes, test name
(e.g.: TEST), main DET.P.m=12 (main DET.P.l,n,p,r has not been entered yet)
in the number without any analytical conditions, and save them.
3-14
3 SETTINGS
3.1.16c Measure the reagent blank for calibration in the serum index measurement
test as set in 2.
3.1.16d Set in Setup — Analytical Parameters (Serum) (Password: manager).
① ②
3-15
3 SETTINGS
① Register the tests which can be used for serum index measurements in the
test column (up to 10 tests).
If you made the settings in Compulsory test analysis in 1 above, enter the
test set in 2 above in test No.1. Set usual tests in test No. 2 and after.
② Set coefficients a to f for each test.
- In the case of the test for serum index measurement (R1=100 ㎕ , SV=2 ㎕ ),
a=1128.90, b=167.54, c=39.08, d=0.8987, e=0.1488, f=1.3289
- In the case of setting the other tests in No.2 and after, if R1 volume, Sample volume
(Serum) are different from the saline test, calculate the coefficients a to c for each
test, and set them.
Calculation formula a’={(R1+SV)/102}×(2/SV)×a (same for b’ and c’)
e.g.: Where 80 ㎕ to AST R1, 4 ㎕ to SV,
a'={(80+4)/102}×(2/4)×1128.90=464.84
③ Set Qualit.judge of chyle, hemolysis, and icterus to Not do, and set Digits
to 2 and analyze samples at the borders of chyle, hemolysis, and icterus, re-
spectively. From the results, set the respective Qualit.judge to Do. In the
Qualitative Judgement set window, set the characters to be used in Char-
acters, and set printed values of the samples at the borders in Border val-
ues.
Request the analysis of the samples that have chyle, hemolysis, and icterus, and then
check that the results of the Characters are correct for each sample.
In the above example, ± is displayed for data with a measured value of 1 to 2.
3-16
3 SETTINGS
3-17
3 SETTINGS
3-18
3 SETTINGS
3-19
3 SETTINGS
3-20
3 SETTINGS
3-21
MAINTENANCE
4
4.1 MAINTENANCE CHECKLIST ................................................................. 4-1
4.2 BEFORE STARTING OPERATION.................................................................. 4-4
4.2.1 Check the purity of water in the Pure Water Supply Unit .......................... 4-4
4.2.2 Check and clean the tips of probes (SPP, RPP1 and RPP2) ....................... 4-4
4.2.3 Check and clean the mixing rods................................................................ 4-6
4.2.4 Check and clean the splash covers ............................................................. 4-6
4.2.5 Check WUD and RRV Top Cover .............................................................. 4-6
4.2.6 Check and clean Wash Ports Check overflow of Pure
Water and Wash Solutions Check and clean the Overflow Sensor.......... 4-7
4.2.7 Check the pumps for leak Check the cylinder for air
bubbles ....................................................................................................... 4-7
4.2.8 Check and clean the ISE dilution bowl ...................................................... 4-8
4.3 DAILY AND WEEKLY WASH ......................................................................... 4-8
4.4 REGULAR MAINTENANCE ......................................................................... 4-10
4.4.9 Lamp Energy Check................................................................................. 4-10
4.4.10 Cuvette Blank ........................................................................................... 4-12
4.4.11 Shutdown Operation................................................................................. 4-14
4.4.12 Cleaning ISE Dilution Bowl..................................................................... 5-10
4.4.13 ISE Line Wash .......................................................................................... 5-11
4.4.14 Lamp Coolant Refill ................................................................................. 4-14
4.4.15 Cleaning Waste Fluid Lines for Probe Wash Ports and Mixer Wash
Ports.......................................................................................................... 4-14
4.4.16 Cleaning LWP Line Filter ........................................................................ 4-15
4.4.17 Cleaning Mixing Rods.............................................................................. 4-16
4.4.18 Disk defragmentation for PC with WindowsXP ...................................... 4-18
4.4.19 Cleaning ISE waste drain nozzle.............................................................. 5-10
4.4.20 Cleaning RTT, CTT and STT trays .......................................................... 4-19
4.4.21 Cleaning filter for cooling part of the chiller............................................ 4-20
4.4.22 Cleaning the cuvette wash solution bottle and cuvette conditioner
bottle......................................................................................................... 4-20
4.4.23 Cleaning line filter for consumable bottles .............................................. 4-21
4.4.24 Cleaning Detergent Lines (WUD)............................................................ 4-21
4.4.25 Cleaning fans ............................................................................................ 4-24
4.5 REGULAR PARTS REPLACEMENT ............................................................. 4-25
4.5.26 Replacing Lamp........................................................................................ 4-25
4.5.27 Replacing ISE Electrodes ......................................................................... 5-13
4.5.28 Replacing Reaction Cuvettes (this should be done when the power is
off) ........................................................................................................... 4-26
4.6 OTHER MAINTENANCE............................................................................... 4-27
4.6.29 When the pure water tank is empty .......................................................... 4-27
4.6.30 Removing air from cuvette wash solution line and cuvette
conditioner line ......................................................................................... 4-30
4.6.31 Replacing the SPP probe........................................................................... 4-30
4.6.32 Replacing RPP1 and RPP2 probes............................................................ 4-33
4.6.33 Replacing L-Ring set (1 mm) of sample pump(SP) ................................. 4-35
4.6.34 Replacing L-ring sets (5mm) of RP1 and RP2, and OMNISEAL
(14mm) for SRWP .................................................................................... 4-36
4.6.35 Replacing mixing rod................................................................................ 4-40
4.6.36 Removing clot in WUD ............................................................................ 4-41
4.6.37 Backing up system file to DVD ................................................................ 4-43
4.6.37a How to perform a backup .................................................................. 4-43
4.6.37b Restoring data from a backup disk .................................................... 4-44
4.6.38 Recovering from a power failure and computer maintenance .................. 4-45
4.6.38a Recovery from an unexpected power failure..................................... 4-45
4.6.38b Checking the behavior of the workstation......................................... 4-45
4.6.38c Workstation problems........................................................................ 4-45
4.6.38d Using the manual for the JCA-BM6010/C Automatic Analyzer....... 4-46
4.6.38e Others ................................................................................................ 4-47
4.6.39 Before a long period of nonuse................................................................. 4-47
4 MAINTENANCE
REQUIRED
MONTHLY
MONTHS
MONTHS
WEEKLY
REFER
EVERY 3
EVERY 4
DAILY
TO
REMARKS
AS
ITEM
MONTHS
WEEKLY
REFER
EVERY 3
EVERY 4
DAILY
TO
REMARKS
AS
ITEM
4-1
4 MAINTENANCE
See remarks
100 or more samples /month ->
13 Clean the ISE line every week 5-11
Less than 100 samples /month
-> every 2 weeks
Note: if there is no dialysis
sample ->every 1 to 3
months
14 Add lamp coolant √ 4-14
Avoid clogging in the waste Maintenance frequency
15 fluid line for wash ports for √ depends on how many 4-14
probes and mixing rods analyses are run.
Clean the LWP line filter Frequency depends on the
16 √ quality of water
5-15
MONTHS
MONTHS
WEEKLY
REFER
EVERY 3
EVERY 4
DAILY
TO
REMARKS
AS
ITEM
4-2
4 MAINTENANCE
REQUIRED
MONTHLY
MONTHS
MONTHS
WEEKLY
REFER
EVERY 3
EVERY 4
DAILY
TO
REMARKS
AS
ITEM
Lift the top cover if necessary and perform the checks described below.
4-3
4 MAINTENANCE
反应杯冲洗站WUD
灯室冷媒
样本盘 急诊位
试剂针RPP2
内圈稀释样本盘CTT 试剂针RPP1
试剂盘RTT2 试剂盘RTT1
外圈初始样本盘STT
4.2.2 Check and clean the tips of probes (SPP, RPP1 and RPP2)
Cleaning method:
① Lift the shaft of the probe arm and manually rotate the probe into a position
where you can wipe the tip of the probe easily. When you rotate the probe,
be careful not to crush it against the V-block.
If necessary, remove the STT, CTT or RTT cover when cleaning the probe.
Alternatively, select Manual Operation in Maint. (see P6-39) and double-click
16.SPPLR, 37.RPPLR-1, or 49.RPPLR-2 when the analyzer is in READY
mode. Click Move in the dialog box to move the probe to the preferable po-
sition for cleaning.)
4-4
4 MAINTENANCE
• When you clean the tip of the SPP, move the SPP over the STT.
• When you clean the tip of the RPP, move the RPP over the RTT where reagents
are not loaded.
② Wipe the exterior of the probe with gauze moistened with pure water.
③ Move the probe right and left to see if the tip of the probe can move without
crushing to the V-block.
④ Exit the Manual Operation window and select INITIALIZE to return to
READY mode.
You can also check if pure water is coming out straight from the tip of the
probe during initialization to see there is no clogging in the probe.
When cleaning the probe with the power of the analyzer turned off, the arm of the
probe may go down due to its own weight. Lift the unit and carefully move it so
that you will not crush the tip against other components.
During initialization, the arm of the probe goes down two to three millimeters from
the original position. After cleaning, move the probe to a position where nothing is
underneath before performing INITIALIZE to prevent probe crush against other
components on the analyzer.
4-5
4 MAINTENANCE
Leak sensor
4-6
4 MAINTENANCE
Overflow sensor
V block
Check the 4 wash ports (SPP, RPP1, RPP2 and ISE wash port) as well as the 2 mixing rod
ports (MIX 1 and MIX 2).
Move the arm of the probe as described in “Check and Clean the Tip of Probes” in this
section. Clean the V-block, the overflow sensor and the surrounding areas with cotton
buds or gauze.
4-7
4 MAINTENANCE
Cotton bud
ISE nozzle
給液ノズル
Please contact our service personnel about the daily and weekly wash. Frequency and
type of wash depends on the analyses you run.
As the hypochlorous acid soda in Reagent Probe Wash-S is easily decomposed, make 5%
solution every time before use. Set the 5% solution of Probe Wash on RTT just before
use and remove it immediately when the wash is completed.
Apply the same method to the ISE electrode wash solution: Set the wash solution just
before use and replace it everyday.
4-8
4 MAINTENANCE
To prevent contamination
No.42 in RTT1 and RRT2 REAGENT PROBE WASH-1
(alkali)
To prevent contamination
No.43 in RTT1 and RTT2 REAGENT PROBE WASH-2
(acid)
Detergent container
Incubation bath oil Reaction Bath Oil
(third from the right)
Detergent container
ISE buffer solution ISE BUFFER
(far left)
Regularly check the joint of the tubing for loosening and perform visual check if
there are any air bubbles in the bottles.
4-9
4 MAINTENANCE
[Figure 1]
This will start the RPP1 (Reagent Probe 1) to aspirate pure water from Position 45 on
RTT1 and to dispense it into the Reaction Cuvette no.1. The RRV (Reaction Carousel)
rotates until the cuvette is in the position for the lamp energy measurement. When these
operations are completed, the System Status display in the Operation Panel window
changes from LUMI.CHECK to WAIT.
⑤ Set 1000 and 100 (µ sec) in Meas.times and Meas.cycle respectively for
Luminous energy check as shown in Figure 2.
⑥ Click Meas. Energy and then click OK for the message ‘Execute the lamp
energy check?’. Measurement will finish in approximately one second.
[Figure 2]
4-10
4 MAINTENANCE
⑦ Select ‘340nm’from the dropdown, select ‘AD’ radio button and select ‘Auto’
radio button. Then click Collect Data to display the data. Check the AD
value at 340nm.
Do not use Offset AD transfr, Offset meas., Offset AD collect oand Offset AD
regist. buttons in this operation.
4-11
4 MAINTENANCE
4-12
4 MAINTENANCE
Flags
Setting the meadian of the cuvette blank values for all 231 cuvettes as the standard,
[H] or [L] flag is generated against the OD value that exceeds either +0.4OD or
–0.4OD.
[H] and [L] flags indicate that the cuvette is defective. Check the measurement
value for the cuvette in [RealTime Monitor] window.
4-13
4 MAINTENANCE
Lamp coolant
4.4.15 Cleaning Waste Fluid Lines for Probe Wash Ports and Mixer
Wash Ports
This operation is to prevent clogging in the waste fluid line probes.
① Carefully inject about 20 ml of REAGENT PROBE WASH-S (undiluted) into
the wash port with syringe. Avoid overflowing. Be careful not to crash into
the probe.
4-14
4 MAINTENANCE
4-15
4 MAINTENANCE
④ Put the mesh filter back into the filter case and install the filter case in the
original position.
⑤ In the Menu window, select Maint. and then Manual Operation. Double-click
71.LWP and check that there is no water leak from the pipe joints and the fil-
ter case.
⑥ Turn the LWP Flowrate Adjustment valve to set the LWP Pressure gauge to a
range between 70 kpa to 72 kpa.
⑦ Exit the Manual Operation window and initialize the system to READY mode.
4-16
4 MAINTENANCE
⑤ Double-click 44.MUD1 to open the window to operate MIX1 (up and down).
⑥ Click the Init. button to put MIX1 into its wash port.
⑦ Do the same operations for 56.MUD2 to put MIX2 into the wash port.
⑧ Leave the mixing rods in the wash ports for about 10 minutes.
4-17
4 MAINTENANCE
② Click Start at the bottom left of the screen, then select Programs, Accesso-
ries, System Tools and Disk Defragmenter. (If the Disk Defragmenter icon
is displayed on the desktop, double-click it.)
4-18
4 MAINTENANCE
④ When the disk defragmentation completion window appears, close all the
windows.
⑤ Click Start at the bottom left of the screen and select Shutdown to restart in
order to complete the defragmentation.
③ Wipe off the condensation inside the CTT and clean the trays.
(Check that the tube holders are in good condition with no defect.)
4-19
4 MAINTENANCE
④ To clean RTT1 and 2 trays, turn the handle in the center to remove the trays
and wipe off any condensation.
⑤ To replace an RTT tray, place the tray over the pin with a triangular mark so
that the pin fits into the hole of the tray.
Turn the screw of the center handle until it is tightly fastened.
Turn the trays manually with your hand to check they are securely fixed in the
correct position and the movement of the trays is smooth and flat.
Triangular mark
② Remove particles and dirt on the filter by a vacuum cleaner. Put back the filter
to its original position.
4.4.22 Cleaning the cuvette wash solution bottle and cuvette condi-
tioner bottle
Remove the bottle sensor and the aspiration tube to wash inside the bottle.
(Do not clean the Reaction bath oil bottle.)
4-20
4 MAINTENANCE
Seventh portSixth port Fifth port Fourth port Third port Second port First port
I C3 B3H5G F H4C2 B2H3E D H2C1 B1H1A
赤1
Red 1
4-21
4 MAINTENANCE
Fixing screw
⑤ Put the silicon tubes in a container that is filled with 150 ml of 50% hypochlo-
rite solution or 1N - NaOH aqueous solution. (Important: Do to use foaming
detergent. Do not pour more than 150 ml.)
You can place the nozzles directly into the container. When you do so, do not put
the WV nozzle in the container. Do not soak the WUD deeper than nozzles in the
solution.
WV nozzle
Do not soak
nozzles deeper
than this level.
4-22
4 MAINTENANCE
⑥ In the Menu window, select Maint., then select User Maintenance to open
the User Maintenance window.
⑦ Click WASH Start in Cuvette Detergent Aspirate Line Wash, and then se-
lect Yes in the window as shown below. The nozzles start aspirating the so-
lution for one minute for washing.
⑧ The following message appears when the wash is completed. Leave the
lines for a few minutes. Replace the silicon tubes in a container filled with
150 ml pure water. Click OK in the dialog box below. The nozzles start as-
pirating the pure water.
4-23
4 MAINTENANCE
⑩ Wipe the tip of each nozzle that you washed, remove the towel and the plastic
sheet and return the WUD to the original position. Observe the WUD from the
side to see if the tips of the nozzles are in the correct positions and then
tightly fasten the fixing screw.
⑪ Perform INITIALIZE.
⑫ Check the positions of the nozzles.
In the Menu window, select Maint. and then Manual Operation. Dou-
ble-click 23.WUD to open the window shown below. Click Move to
lower the WUD. Lower the nozzles carefully. Check that the wash nozzles
are correctly positioned in the center of the cuvettes. Click the Init. Button
to move up the WUD to the original position. Click Exit to close the Manual
Operation window.
4-24
4 MAINTENANCE
④ Install a new lamp in the lamp housing and securely fasten the fixing screws
and cable screw bolts.
Do not touch the glass portion of the lamp.
⑤ Turn on the analyzer by setting to PC CONTROL. Perform INITIALIZE,
then check that the analyzer is in READY mode.
⑥ Wait for 30 to 40 minutes for the lamp to stabilize. In the Menu window, se-
lect Maint. and then Lamp Energy Monitor to check the lamp energy.
Select Maint., then User Maintenance
to start the cuvette blank measurement.
4-25
4 MAINTENANCE
4-26
4 MAINTENANCE
If you experience what is described in (2), remove the air bubbles by following the steps
below.
Aspirate cuvette
セル洗浄水 VP真空
wash water
セル洗浄
Cuvette wash line 吸引 To VP vacuum pump
ポンプへ
Wash SPP and RPP
SPP,RPPを洗浄 (water supply)
ライン
LWPに空気が入った時、
(給水) Wh
LWP圧力 このマニュアルコックを開け、
this manual cock
ゲージ
LWP pressure gauge
LWP Flowrate
Adjustment valve valve and
LWPに水を満たす
LWP with water.
en
LWP流量調整弁
70~72 kPa
76kPa
SRWP (LWP.W.V)
Probe
ピペット
Mixing
攪拌棒 rod
GE
Water
ミニクリアsupply
LWPライン Equipment
LWP line filter
フィルタ Analyzer
本体
純水分岐ジョイ
Pure water branching
ント(J4)
joint (J4 Manifold)
LWP 70 ~72Pure
kpa water bottle WEV
純水タンク
4-27
4 MAINTENANCE
Closed Open
(Normal Status)
c. Turn the LWP Flowrate Adjustment valve fully clockwise to fasten it.
4-28
4 MAINTENANCE
d. Check the LWP pressure gauge. If 100kPa (---) or greater is shown, it indi-
cates air bubbles have been removed.
If the pressure does not rise up to this level, turn the LWP Flowrate Adjustment
valve counterclockwise to open it and keep it at that position for 10 to 20 sec-
onds. Fasten the valve and check if the pressure rises. If the pressure does not
rise, even after you repeat this operation several times, start the operation again
from 3. Remove air bubbles in LWP
If your analyzer unit has been used for a long time, this operation can wash the
line contamination into the filter. This may lead to difficulties in increasing
pressure. If this is suspected, double-click 71.LWP to set it to OFF, clean the
LWP line filter (see P 4-15), and then double-click 71.LWP to set it to ON and
check the pressure.
e. Turn the LWP Flowrate valve counterclockwise to open it and adjust the
pressure to approximately 70 to 72 kPa.
⑤ Remove air bubbles from the probe and mixing rod tubes.
a. Check that the pressure that the LWP pressure gauge shows the range
around 70 to 72 kPa.
b. Cover SPP V-blocks with gauze. (There are two SPP V-blocks.)
RPP2 54.RPEV2-2
f. When air bubbles are removed from all the V-block tubes, close the Manual
Operation window, click INITIALIZE on the workstation and check READY
is displayed for the analyzer.
g. Check that there is no leakage in the analyzer unit.
4-29
4 MAINTENANCE
⑥ After the above steps, set all lines to 10 times for PRIME 2 or 3 to remove air
bubbles from probes and cuvette wash lines.
⑦ Perform WASH3 to remove small air bubbles.
4.6.30 Removing air from cuvette wash solution line and cuvette
conditioner line
Perform the following steps when the lines are completely empty.
① Check that the filter of the aspiration nozzle is not contaminated.
② Check that the pipe joint installed on the tank lid is not loose.
③ In the Menu window, select Maint. to open the Manual Operation window.
④ Double-click 59.VP so that ON is displayed.
⑤ For the cuvette wash solution line, double-click 24.AEV1 and 62.VEV1 so that
ON is displayed for both. For the cuvette conditioner line, double-click
34.DCEV1 and 63.VEV2 so that ON is displayed for both.
⑥ Wait for 10 seconds, and then double-click 62.VEV1 for the cuvette wash so-
lution line and 63.VEV2 for the cuvette conditioner line to display OFF.
⑦ Close the Manual Operation window, click INITIALIZE in the workstation,
and check if the mode is READY.
⑧ Select WASH3 and check that there is no leak from the WUD (R2 for the cu-
vette wash solution and R4 for cuvette conditioner) and that there is no inclu-
sion of air from the tank lid joint.
4-30
4 MAINTENANCE
Pipe fitting Square shape joint Terminal fixing screw1 Post Terminal 1
Terminal 2
Terminal fixing screw2 Sensor board
Spring
⑤ While pressing the square shape joint with your fingers, turn the pipe fitting
counterclockwise with needle nose pliers and then loosen it manually to re-
move it. If you experience any leaks from the probe as you do this task, wipe
the leaking material with gauze or something similar.
4-31
4 MAINTENANCE
⑥ Hold and lift the end of spring with needle nose pliers to remove it from the
probe.
⑦ Rotate and remove the sensor board while using your fingers to lift the
washer with the U slot under the sensor board.
Sensor board
Washer
⑧ Place a flat bladed screwdriver under the square shape joint to lift it.
Guide
⑨ Hold the probe with your hand, and lift and remove it.
⑩ Insert a new probe in the holder and push the square shape joint vertically
into the guide.
⑪ Lift the washer and rotate and fix the sensor board. (See the illustration for (7)
mentioned above.)
⑫ Hold and lift the end of the spring with needle nose pliers to fix it to the probe.
(See the illustration for (6) mentioned above.)
⑬ While holding the square shape joint with your fingers, turn the pipe fitting
clockwise a few times and fasten it tightly. Fasten it for another 30 degrees by
using the square shape joint. Be careful not to damage the thread of the pipe
fitting.
⑭ Replace terminals 1 and 2 and fasten the terminal fixing screws 1 and 2 with
a Phillips screwdriver. As you fasten screws, hold the post under the screws
with needle nose pliers so that it will not move. (See the illustration for (4)
mentioned above.)
4-32
4 MAINTENANCE
⑱ Check if the tip of the probe is positioned at the center of a reaction cuvette.
To fix small displacements, hold and raise the probe arm shaft to the upper-
most level and adjust the probe by bending it. If the displacement is large, the
probe tube may have been installed incorrectly. Check the installation. (If you
reinstall the probe, click INITIALIZE in the workstation and then click Start
again in Position Probes for Routine Cleaning as mentioned in (17).)
⑲ Click INITIALIZE in the workstation to check READY is displayed for the ana-
lyzer.
⑳ Select WASH3 and check for a short period of time that the probe operates
correctly without splattering.
Note: Tighten the splash cover screws before starting WASH 3 so that they
will not fall out.
21 Stop the analyzer and when READY mode is displayed, install the probe arm
cover.
4-33
4 MAINTENANCE
Guide
Terminal
ターミナル2 2
Terminal 1
ターミナル1
Fixed screw D
Fixed screw C
Fixed screw B
Fixed screw A
Holder
Probe
サンプルチューブ
④ While pressing the square shape joint with your fingers, turn the pipe fitting
counterclockwise with the needle nose pliers and then loosen it manually to
remove it. If you experience any leaks as you do this task, wipe the leaking
material with the gauze or something similar.
⑤ Loosen the fixed screws A, B, and C and the square shape joint with a Phil-
lips screw driver. (Do not remove them.)
⑥ Hold the probe with your hand and
lift and remove it. A part Terminal 1
⑦ Insert a new probe in the terminal 1, Stopper
holder, and terminal 2.
⑧ Push the stopper of the probe and
Terminal 1 firmly from the top to
make sure there is no space be- Screw A
tween them, and securely tighten Tight fit
screw A with a Phillips screw driver.
Lift the A part of the probe above the No space between the
stopper to check that it does not stopper and Terminal 1.
move.
⑨ While holding the probe with your hand, tighten the probe screws B and C
and the square shape joint fixing screw with a Phillips screw driver. Do not
tighten the square shape joint fixing screw too hard so you do not damage the
guide.
⑩ While holding the square shape joint with your fingers, turn the pipe fitting
lightly clockwise a few times and fasten it tightly. Fasten it another 30 degrees
with needle nose pliers. Be careful not to damage the thread of the pipe fit-
ting.
How to check the operation of probe after replacement See the procedures from
P 4-33 (15).
4-34
4 MAINTENANCE
④ Remove the L-Ring set (seal) installed at the upper part of the holder.
4-35
4 MAINTENANCE
⑤ Use the L-Ring fitting jig, to install a new L-Ring Set (seal) to the upper part of
the holder.
⑥ Adjust the screw holes of the washer and the cylinder so that they match and
then attach them with screw bolts.
⑦ Slowly move the drive lever up and down to see if it moves smoothly.
⑧ Install the cover.
Install the pump
① Put the pump in front of the base and install the two connectors.
② Set the pump on the base and secure it with Philips-head screws.
③ Manually tighten the joints at the upper part and the front of the cylinder and
then tighten another 45 degrees using long-nose pliers.
④ Set the main switch of the analyzer power panel to PC CONTROL.
⑤ Select Re-Start in the BioMajesty Startup window and click INITIALIZE to
display READY mode.
⑥ Set all line times to 10 for PRIME2 and then select PRIME2.
⑦ Select WASH3.
⑧ Check that there is no leaking from the joints and the pump sealing and that
no air has entered the cylinder and then close the door.
Tab
Connector (SP-2)
Tab
RP1 RP2
Connector (SP-1)
4-36
4 MAINTENANCE
Cylinder block
Holder
Spacer Cylinder Remove
② Remove the cylinder block by gently pulling in the direction of the arrow.
(Pull the cylinder block only as the pump piston cannot be removed.)
Note: The white 5 radius piston is made of ceramic and can be damaged
easily. Handle with care.
L-Ring Set
Spacer
Cylinder
Piston
Piston
Cylinder block
Cylinder fixing bolt
③ Remove the three cylinder screw bolts attached to the cylinder block. The
cylinder block can be disassembled into the spacer, the holder with L-Ring
sets (seal) and the cylinder.
④ Using the removing tool, remove the two L-Ring (seal) sets without damaging
the holder.
⑤ Use pure water to clean the spacer, holder, cylinder, and piston you removed.
Wipe the pump unit if wet.
⑥ Apply silicon grease lightly inside the holder where the L-Ring sets (seal)
touch.
4-37
4 MAINTENANCE
⑦ Using the L-Ring fitting jig, set a L-Ring set (seal) on each side of the holder
without twisting the new L-Ring set.
⑧ Assemble the spacer, holder, and cylinder by adjusting the marks. Push the
spacer evenly from the top and loosely fasten the three cylinder screw bolts.
Next, insert the L-Ring fitting jig of the same diameter and evenly tighten the
three cylinder screw bolts evenly and then remove the jig.
⑨ Attach the cylinder block to the pump unit and push it straight.
⑩ Attach the two cylinder block screw bolts and fasten tightly.
SRWP (OMNISEAL)
① Prepare two pieces of pump seal (14mm OMNISEAL set) for one pump.
② Mark the joint fixing hole (front facing) on the Nut and the ring to align their
positions when they are reassembled.
Turn right
Nut
③ Turn the nut fixing the Nut and the spacer to the right. When the nut is re-
moved, the cylinder block can be disassembled as shown in Figure 1.
Nut
OMNISEAL
<b>
<a>
④ Use the removing tool to remove the two OMNISEAL sets from the Spacer
and the cylinder.
a. Insert the L-Ring removal jig 5mm into the OMNISEAL
b. Tilt the L-Ring removal jig slightly.
c. While maintaining the tilted position, remove the OMNISEAL.
4-38
4 MAINTENANCE
Jig
OMNISEA
Cylinder Spacer
⑤ Insert a new omni seal set into the Spacer and the cylinder by using the fitting
jig.
Attaching an OMNISEAL with the jig
Cylinder OMNISEAL
Spacer
Jig
⑥ Match the spacer pin with the holder fitting hole, and the Spacer pin with the
cylinder fitting hole to fix them.
<a> Pin
Spacer
Holder
Fitting hole
Spacer
Cylinder
⑦ Lastly, turn the nut to the left and fasten tightly (in the order shown in Figure
1) until the mark on the cylinder meets the mark on the nut.
4-39
4 MAINTENANCE
③ Push the mixing rod straight up from the bottom and then rotate in direction of
the arrow to fix (counterclockwise when viewed from above, the opposite of
(2)).
④ Check the mixing rod is firmly attached and then clean it with the gauze or
something similar. Remove the gauze or similar material that is covering the
cuvettes.
⑤ Select INITIALIZE and check that the system is in READY mode.
4-40
4 MAINTENANCE
Check behavior
① Select Maint. and Manual Operation.
② Double-click 44. MUD-1 to open the window to check MIX1. Double-click
56.MUD-2 to open the window to check MIX 2.
③ In the opened window, click Init. to return the mixing rod to the wash port.
When you slowly click Move twice after the mixing rod has returned to the
wash port, the mixing rod enters a cuvette.
④ Close the 44. MUD-1 or 56.MUD-2 window.
⑤ Double-click 45. MIX-1 or 57. MIX-2 to open the corresponding window.
⑥ Click Move in the window. The mixing rod moves back and forth in the cuvette
and stops after a short period of time. Check that the mixing rod does not hit
the cuvette while in motion.
⑦ Close the 45. MIX-1 or 57. MIX-2 window.
⑧ Double-click 40.MIXR-1 or 52.MIXR-2 to open the corresponding window.
⑨ Click Move in the window. The mixing rod starts to rotate in the cuvette and
then stops after a short period of time. Check that the mixing rod does not hit
the cuvette while it is rotating.
⑩ Close the 40.MIXR-1 or 52.MIXR-2 window.
⑪ Close the Manual Operation window and then select INITIALIZE.
⑫ Select WASH3 and check that the mixing rod does not scrape the cuvette.
Remove a silicon
tube from a nozzle
4-41
4 MAINTENANCE
Joint connection
③ Insert a wire into the nozzle from the top to remove the clot.
④ Wash the inside of the nozzle with pure water by using an injector or some-
thing similar.
⑤ Wipe the exterior of the nozzle and firmly attach the silicon tube.
⑥ Return the WUD to its original position on the analyzer and check the opera-
tion. (see P 4-24 ⑫).
4-42
4 MAINTENANCE
② In the Backup TOOL window, select Make a Backup Copy and System
Files omly (click to clear the Data Files check box),and check that the figure
in Total size is smaller than the figure in Space Available. Use a new DVD if
there is not enough free capacity.
4-43
4 MAINTENANCE
③ When you click Execute, the message “Do you want to make a backup copy
to D:¥ ~ ?” (if DVD is D:¥)appears. Click OK to start the backup. A folder
named with the current date,in which the specifications are copied, is created
in the DVD (D:¥) (20090627 for the window shown above).
④ When backup is completed, a message informing you of the completion ap-
pears. When you click OK to close the message, you will return to the
Backup TOOL window. Click Exit to return to the BioMajesty Startup win-
dow.
⑤ Eject the DVD from the drive, write down the date and version and store it.
Make sure to make a backup after performing an upgrade. If you have multiple ana-
lyzers, make a backup for each analyzer.
4-44
4 MAINTENANCE
⑦ Select New Start in the BioMajesty Startup window to start the analyzer unit
software. Check the specifications and configuration. Modify if necessary be-
fore you start using the system.
Cuvette blank and calibration data are not saved.
4-45
4 MAINTENANCE
Click Task Manager to open the Windows Task Manager window, where a
list of the software programs currently running is displayed. Click the task
with the “Not Responding” status to highlight it in blue and click End Task.
After a short time, the window shown above at the right appears. Click End
Now.
b. If the problem persists even after performing the procedure described in
Step 1, shut down and restart the system. If you cannot shutdown the sys-
tem, click Start located in the corner of the bottom left of the monitor and
select Shut Down to quit Windows and power off the workstation. Follow the
procedure described in 1. “Recovery from an unexpected power failure.”
② When the screen is frozen:
a. While pressing Ctrl and Alt keys together, press the DEL key twice to force
the program to end. (This will reset the computer.)
b. If you still cannot perform keyboard operations even after performing the
procedure described in Step 1, power off the computer by pressing the
power button for 10 seconds. The analyzer unit will also power off. Wait for
10 seconds and then follow the procedure described in 1. “Recovery from an
unexpected power failure.”
In this situation or any similar situation, the customized specifications (for example,
analysis parameters) may be erased because of corruption of the database file. To
avoid this kind of situation, make sure to back up data to a DVD when an analysis
parameter has been changed or a test has been added.
4.6.38d Using the manual for the JCA-BM6010/C Automatic Analyzer
① Click Start located at the bottom left corner on the monitor and select “Manual
for the JCA-BM6010/C Automatic Analyzer” at the top of the Start menu to
open the instruction manual. Select the title of the instruction manual you
want to read. The instruction manuals are provided in PDF format.
② You can navigate to the section you want to read by clicking the section in
the table of contents. Use this function as required.
4-46
4 MAINTENANCE
4.6.38e Others
① Up to 10 BM6010/c windows can be opened at a time. The following message
appears if you attempt to open an extra window. Click OK to slose this dialog
box. Close one of the windows that is already open and then open a new
window.
② The names of the open windows appear when you move the mouse pointer to
the bottom of the screen. The window appears in the foreground when you-
click a window name.
③ If you cannot close a window because it is overlapped by the Menu window
and the Operation Panel window, follow the steps below.
a. Select System(S) in the Operation Panel window and click Top Display
once to cancel the settings of the topmost window.
b. Click a part of the overlapped window to display it in the upper right fore-
ground.Close that window.
c. Select System(S) in the Operation Panel window again and click Top Dis-
play to restore the settings.
4-47
4 MAINTENANCE
4-48
5
ISE UNIT
5.1 OVERVIEW ....................................................................................................... 5-1
5.2 ANALISYS OPERATION ................................................................................ 5-1
5.3 ROUTINE OPERATION AND CALIBRATION .............................................. 5-1
5.3.1 Start-up ....................................................................................................... 5-1
5.3.2 Calibration .................................................................................................. 5-1
5.3.2a Measurement ....................................................................................... 5-1
5.3.2b Data (Request — RealTime Monitor) ................................................... 5-2
5.3.3 Control, Sample Measurement ................................................................... 5-5
5.3.4 Single operation of ISE module ................................................................. 5-5
5.3.5 End Operation ............................................................................................ 5-5
5.4 SETTINGS ......................................................................................................... 5-5
5.4.1 Basic Setting............................................................................................... 5-5
5.4.2 User Setting ................................................................................................ 5-6
5.5 MAINTENANCE............................................................................................... 5-8
5.5.1 Checking ISE Buffer Level ........................................................................ 5-9
5.5.2 Checking Internal Standard Level.............................................................. 5-9
5.5.3 Washing Electrode and End Operation....................................................... 5-9
5.5.4 Cleaning ISE Dilution Bowl..................................................................... 5-10
5.5.5 Washing ISE Waste Drain Nozzle ............................................................ 5-10
5.5.6 Washing the ISE Line (Use Dummy electrode, ISE detergent
solution, probe)......................................................................................... 5-11
5.5.7 Conditioning Electrode (Electrode Na,K only) ....................................... 5-12
5.5.8 Replacing ISE Electrodes ......................................................................... 5-13
5.5.9 Storing Electrodes .................................................................................... 5-14
5.5.10 Long-term Storage of ISE module ........................................................... 5-14
5.6 ISE UNIT LAYOUT ......................................................................................... 5-15
5.7 ISE MODULE SCHEMATIC DIAGRAM....................................................... 5-15
5 ISE UNIT
5.1 OVERVIEW
Favorable data can be obtained with high-speed response, high selectivity, and high sta-
bility as a crown ether membrane is utilized for the sodium electrode (Na) and potassium
electrode (K) and a newly developed molecular-oriented membrane is utilized for the
chloride electrode (Cl). Calibration can be started simultaneously with other chemical
tests using the dedicated ISE serum and the urine standards (Low and High). After that,
you can perform control and sample analysis similar to other chemical tests.
5.3.2 Calibration
Measure calibration every day before measuring a sample. Also, measure calibration after
replacing the ISE buffer solution, Internal standard solution, or electrode, and after main-
tenance.
5.3.2a Measurement
① Pour approximately 500 μl of serum ISE Standard of Low-STD and serum ISE
Standard of High-STD (urine Low-STD and urine High-STD in the case of
urine analysis) into sample cups and set them at the STD position of CTT.
Note: The STD positions and the container types are set in the Setup — ISE
Parameters Setting window. (See P 5-7). Examples at delivery are C-11, 12,
13, and 14.
② You can similarly perform the START operation simultaneously with the cali-
bration of the chemical tests. The ISE analysis is performed in the order of
serum High-STD and then, Low-STD (if urine analysis is to be made, urine
High-Low follows after that). Each STD is measured at least three times
5-1
5 ISE UNIT
Base
Base
Base
Base
Base
Base
5-2
5 ISE UNIT
Flagged:
Slope alarm flag (l.h) Ref electrode If a Slope is out side the
Abnormal slope (H,L) control value of Ref If a dilution factor is
range from 38 to 65,it is outside the range from
Abnormal Dilution factor electrode :Flagged “d” abnormal 25 to 60, it is abnormal
abnormal (d) when this value becomes
Abnorma bial abnormal (NG) 350 or less
The above display appears when the RealTime Monitor display is in the Standard
setting. For the Conc. setting, only S-B potential difference and ISE calibration
result appear.
① Averages of the last two data of High-STD and Low-STD are each stored as
results.
② Temperature of measured solution is always measured by thermistor and
measurement result is displayed as TH. The very last measured value of
H-STD and L-STD will be saved.
③ Slope and Dil.factor are calculated from the results of High-STD and
Low-STD.
④ The results appear in the Maint. — ISE Monitor window. You can check them
with the previous ones.
Base Base
Base Base
Base
5-3
5 ISE UNIT
5-4
5 ISE UNIT
cute so that analysis can be performed using the calibration result. After that,
be sure to perform re-calibration before sample analysis.
In order to shut down BioMajesty, fill the ISE Dil.Bowl with pure water before
shutting it down. This prevents the electrodes from drying out. Execute the Final
operation in the Maint. – ISE Operation window, or pour 1 ml of pure water into
the ISE Dil.Bowl with a dropper. In order to automatically end the analyzer unit, you
can set the End ISE operation in Shutdown. (See P1-20)
If the analyzer unit is powered on and the analyzer is used even if only temporarily
after the ISE end operation, water in the Dil.Bowl is drained.
Be sure to refill pure water in Dil.Bowl after that.
5.4 SETTINGS
5.4.1 Basic Setting
① System Specifications Set (initial setting)
ISE Module, Avail.
② ISE Parameters setting (initial setting)
5-5
5 ISE UNIT
5-6
5 ISE UNIT
5-7
5 ISE UNIT
5.5 MAINTENANCE
■ Regular maintenance and washing
Every Every 3 Every Every 2 One Irregu-
No Item Remarks
day days week weeks month larly
Addition of ISE Buffer is
1 Checking Buffer level ○
only once
Internal Standard Do not add internal
2 ○
level standard
3 Washing Electrodes ○
Washing ISE Anytime if crystals are
4 ☆ ○
Dil.Bowl found
Anytime if crystals are
5 Washing ISE WB ○ ○
found
Number of processed di-
alysis samples
Note 1: 500 sam-
ples/month or more
Note 2: 100 sam-
○ ○ ○ ○ ples/month or more
6 Washing ISE line
Note 1 Note2 Note 3 Note 4 Note 3: 100 sam-
ples/month or less
Note 4: 1 to 3 months
without any dialysis
samples
■ Other operations
When replaced with a new Elec-
7 Electrode aging ○
trode
In the case of Slope failure or
8 Electrode replacement ○
Selectivity
Maintenance for
9 ○ When stopped for 3 days or more
long-term storage
10 Notes for long-term stop ○ When stopped for 3 days or more
☆:See P 5-9 section5.5.4
For maintenance, open the top cover and the cover at the electrolyte sample dispens-
ing position, and perform the operations mainly in the Main – ISE Operation win-
dow.
• For maintenance, click ISE-WASH-ON in the Operation Panel Window, and per-
form maintenance with the display set to ISE-WASH-OFF. After the maintenance is
complete, execute INITIALIZE on the unit or Execute of Initialize on ISE Opera-
tion so as to return to ISE-WASH-ON.
• If water or ISE buffer solution is spilled, clean it up immediately.
5-8
5 ISE UNIT
5-9
5 ISE UNIT
If the analyzer unit is powered on and analyzer unit is used even if only temporarily
after the end operation of the ISE unit, the pure water in the Dil.Bowl is drained.
Execute Final Operation in Maint. – ISE Operation, or pour 1 ml of pure water
into the Dil.Bowl using a dropper.
① Set to ISE-WASH-OFF.
② Open the cover at the sample dispensing position, loosen and slide the screw
found on the stainless cover at the upper part of the ISE unit to the front; then
remove the cover.
③ Fill several mL of pure water in the Dil.Bowl and the tray using a dropper.
④ Leave it for about 5
minutes.
⑤ Set 5 in Times in
Dropper
Dil.Bowl Drain in
the ISE Operation
window, and click
Execute to drain
water.
⑥ Wipe off the remaining water or stains around a liquid supply with gauze or a
cotton stick or other similar materials.
⑦ Slide the upper-part of the stainless cover of the ISE unit to mount, and fix it
by tightening the screw. Be careful not to damage the tube or the Dil.Bowl
when sliding the cover. Also, check that the cover fits in the groove and is not
loose.
⑧ Mount the cover at the sample dispensing position.
⑨ Set 2 to 3 in Times of prime in the ISE Operation window, and click Exe-
cute.
⑩ Execute INITIALIZE of ISE module and return to ISE-WASH-ON.
5-10
5 ISE UNIT
② Open the cover at the sample dispensing position, loosen the screw on the
stainless cover at the upper part of the ISE unit, slide it to the front, and re-
move it. (See 3. Cleaning ISE Dil.Bowl,(2).)
③ Remove the thumb-screw and then remove the Waste Drain Nozzle with the
pipes attached.
④ Remove the adhering crystals with paper or similar material, and wash the
nozzle with pure water.
⑤ Return the waste fluid nozzle to the wash bottle (paying attention not to break
the tube) and secure it with the thumb-screw.
⑥ Set 4 or 5 in prime in the ISE Operation window, and execute it. Check that
the fluid is not accumulated in the wash bottle at this time.
⑦ Mount the stainless cover and the cover at the sample dispensing position
(see 3. Washing ISE Dil.Bowl, (7), (8)).
⑧ Return to ISE-WASH-ON.
thumb-screw
5.5.6 Washing the ISE Line (Use Dummy electrode, ISE detergent
solution, probe)
① Set to ISE-WASH-OFF.
② Open the cover at the sample dispensing position, and loosen the screw on
the stainless cover at the upper part of the ISE unit. Slide it to the front and
remove it. (See 3. Washing ISE Dil.Bowl, (2).)
③ Remove Electrodes Na, K, Cl, Ref. (See Replacing Electrodes.)
④ Mount the Dummy electrode instead of the Electrode Na, K, Cl, Ref.
⑤ Remove the cap of the Dummy electrode.
⑥ Use a dropper to pour approximately 5 ml of ISE detergent solution into the
Dummy electrode.
⑦ Securely tighten the cap of the Dummy electrode. ropper
5-11
5 ISE UNIT
⑧ Click Execute(STEP-1) in ISE line wash in the ISE Operation window, and
perform washing. The washing will end in about 16 minutes.
⑨ After the washing is complete, return the Dummy Electrode to the Electrode
Na, K, Cl, Ref. At this time, make sure to check that a small black O-ring is
mounted on each Electrode. (This may result in leakage if it is missing.)
⑩ Click Execute(STEP-2) in ISE line wash in the ISE Operation window to
perform washing. Buffer prime will be performed 10 times.
⑪ Mount the stainless cover and the cover at the sample dispensing position
(see 3.Washing ISE Dil.Bowl, (7), (8)).
⑫ Return to ISE-WASH-ON.
⑬ Perform the calibration before sample measurement.
5-12
5 ISE UNIT
5-13
5 ISE UNIT
If you are finished using the electrode, store it after washing it.
(If the electrode has a lid for the terminal end, store it with the lid closed as be-
low.)
① Cl, Na, and K・・・Store them in a refrigerator in a case containing ISE buffer
solution.
If you use the electrode again, take it out of the refrigerator at least 6 hours be-
fore and let it return to room temperature before using it.
② Ref・・・ Dampen the sponge in the case with pure water, place the Electrode
Ref on it, close the lid, and store it at room temperature.
Store it in a moisturized condition but do not store it in water.)
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5 ISE UNIT
排空电磁阀 缓冲液电磁阀
脱气罐
Degasser 内标液电磁阀
废液瓶
Wash Bottle
Sylinge 注射器:排空、内标液、缓冲液
Degasser
Electrode
Degasser
Drain
5-15
USER INTERFACE
6
6.1 SYSTEM ............................................................................................................ 6-1
6.1.1 BioMajesty Startup window ....................................................................... 6-1
6.1.2 Menu window/Operation Panel window .................................................... 6-2
6.2 OPERATION PANEL WINDOW ...................................................................... 6-3
6.2.1 Start Conditions window ............................................................................ 6-3
6.2.2 STAT Port ................................................................................................... 6-5
6.2.3 PRIME........................................................................................................ 6-7
6.2.4 WASH......................................................................................................... 6-7
6.2.5 Other buttons .............................................................................................. 6-8
6.3 MENU WINDOW.............................................................................................. 6-9
6.3.1 REQUEST .................................................................................................. 6-9
6.3.1a Order Entry ......................................................................................... 6-9
6.3.1b Test Result Monitor ........................................................................... 6-11
6.3.1c 3Review/Edit..................................................................................... 6-13
6.3.1d Reaction Monitor............................................................................... 6-14
6.3.1e Print Report ....................................................................................... 6-15
6.3.1f Statistics ............................................................................................ 6-16
6.3.1g Test Select.......................................................................................... 6-16
6.3.1h Sample Log* ..................................................................................... 6-18
6.3.1i RealTime Monitor ............................................................................. 6-18
6.3.1j Cup/Tube Assign* ............................................................................. 6-19
6.3.1k STAT Order Setup* ........................................................................... 6-20
6.3.1l Correlation* ...................................................................................... 6-21
6.3.2 CALIBRATION ....................................................................................... 6-22
6.3.2a View Calibration Curve .................................................................... 6-22
6.3.2b Test Select.......................................................................................... 6-16
6.3.2c Sample Select .................................................................................... 6-24
6.3.2d Calibration Setup*............................................................................. 6-24
6.3.3 QUALITY CONTROL............................................................................. 6-27
6.3.3a Daily Precision Control..................................................................... 6-27
6.3.3b QC Cumulative.................................................................................. 6-29
6.3.3c Real-Time QC.................................................................................... 6-30
6.3.3d Control Data Registration .................................................................. 6-31
6.3.3e QC Sample Definition* ..................................................................... 6-32
6.3.3f Test Select .......................................................................................... 6-16
6.3.3g Sample Select .................................................................................... 6-24
6.3.4 REAGENT................................................................................................ 6-33
6.3.4a Reagent Test Monitor......................................................................... 6-33
6.3.4b CTT Monitor ..................................................................................... 6-35
6.3.4c Reagent Container Settings ............................................................... 6-35
6.3.5 MAINTENANCE ..................................................................................... 6-37
6.3.5a System Startup/Shutdown Setting ..................................................... 1-22
6.3.5b System Monitor ................................................................................. 6-37
6.3.5c Lamp Energy Monitor ....................................................................... 4-10
6.3.5d User Maintenance.............................................................................. 6-38
6.3.5e Manual Operation.............................................................................. 6-39
6.3.5f System Maintenance Monitor............................................................ 6-42
6.3.5g ISE Operation ...................................................................................... 5-7
6.3.5h ISE Monitor......................................................................................... 5-3
6.3.5i Communication Monitor ................................................................... 6-43
6.3.5j Error Report....................................................................................... 6-43
6.3.5k Liquid Level Sensor Monitor* .......................................................... 6-44
6.3.5l Clot Monitor* .................................................................................... 6-45
6.3.6 SETUP ...................................................................................................... 6-46
6.3.6a System Specification Settings ........................................................... 6-46
6.3.6b Analytical Parameters (Chemistry).................................................... 6-47
6.3.6c System Test List................................................................................. 6-49
6.3.6d Process Sequence............................................................................... 6-49
6.3.6e Analytical Parameters (Serum).......................................................... 6-50
6.3.6f Ratio Parameters................................................................................ 6-51
6.3.6g ISE Parameter Settings ........................................................................ 5-6
6.3.6h Blank Reagent Settings...................................................................... 6-52
6.3.6i Reflex Test Settings ........................................................................... 6-53
6.3.6j Contamination Settings ..................................................................... 6-53
6.3.6k Print Form Settings............................................................................ 6-58
6.3.6l Online Settings .................................................................................. 6-59
6.3.6m Ctrl/Cal Sample Setup ....................................................................... 6-59
6.3.6n Alarm Buzzer Set .............................................................................. 6-60
6.3.6o Setting System Parameters ................................................................ 6-61
6.3.6p Reaction Check Logic ....................................................................... 6-61
6.3.6q Carryover Setting .............................................................................. 6-62
6.3.6r User Code Settings ............................................................................ 6-62
6.3.6s New Test Registration........................................................................ 6-63
6 USER INTERFACE
6.1 SYSTEM
6.1.1 BioMajesty Startup window
Startup
User Name, Password Enter the user name and the password you set in the User Code Set
window.
SN Displays the serial number of the analyzer
Ver No. Displays the version number of the software.
System Date Displays the date when you start the system.
New Start To clear all data and start the system, select this option.
Re-Start To start the system while keeping the data active, select this option.
OK To start the system, click this button.
Shutdown To shutdown Window, click this button.
Back-up Click this button to back-up the system data
Movement Click this button to temporarily transfer specifications, except the ana-
lyzer-specific parameters, from one analyzer to another. Ask service
person for instructions.
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6 USER INTERFACE
Password Use this dialog box to set a password if necessary (See Chapter 3 Settings,
P3-1.)
User Name: Enter manager to dis-
play the Setup menu window.
Setup menu will not be displayed
when logged in as user.
Version Information
Screen Print Click this button to output a hard copy of the screen.
Change User Click this button to change the user name set for starting the sys-
tem.
Exit Click this button to shutdown the system (see Chapter 1 Basic Op-
eration, P 1-17, System Exit).
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6 USER INTERFACE
Operation Panel
Start Conditions
Calibration
Multipnt.smp. Select this Analyze check box when analyzing a multi-
point calibration test. Then, select 98 or 99 for TTNo.
Since the routine sample is analyzed on STT, you can-
not analyze the routine sample and multipoint calibra-
tions at the same time.
Singlepnt.smp Select this Analyze check box when analyzing a single
point calibration test.
Ordinary calib./Special calib. Select the appropriate radio button and click Temp.test
select to change the tests for each calibration
Temp.test select Click this button to temporarily change the tests for
calibration measurement (BLK, STD) and control
measurement.
Temp.sample select Click this button to temporarily change the samples for
calibration measurement.
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6 USER INTERFACE
Control
Control smp. Select this Analyze check box when measuring control sam-
ples.
Temp.test select Same as above.
Temp.sample select Click this button to temporarily change the samples for con-
trol measurement.
Patient sample
Analysis mode Select Barcode for analysis of barcoded samples.
Select Cup posi. for analysis of samples by their cup posi-
tions on the sample tray. (Prior registration of workorder is
required for Cup posi. analysis.)
Tray No. If you select Cup posi. for Analyze mode, enter the STT
number from 1 to 97. It is the STT number you selected
when registering the workorder to the analyzer.
Routine smp. Select this check box to analyze routine samples. Enter the
range of sample positions on STT between 1 and 84.
Temp.cup/tube select You can temporarily change the status, the container and the
Priority of an analysis for each position on STT.
status/container You can temporarily change the container type for each of the
position numbers on STT.
“I” Click Priority to analyze a sample with priority.
Start Click this button to start analysis under the conditions you
have set.
Cancel Analysis will not start if you click this button. However, if
you cancel analysis while the analyzer is in PAUSE mode,
the analyzer will return to START mode.
The same Temp.test select window appears when you click the Temp.test select
button in the Calibration or Control section.
Sample Confirmation
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6 USER INTERFACE
Colors of the Sample ID field When the analyzer reads the barcode, the scanned
sample ID number appears in colored field, indicating the sample
status.
Sample ID field color Sample status
Red The sample is not analyzed yet.
Pink The sample is being dispensed or analyzed for the first time
Blue The sample completed the initial run or rerun.
Light blue Rerun is in process.
Green A sample before analysis (registered).
Gray The analyzer could not read the barcode.
The sample is not registered, or the sample of this barcode
White
number is being analyzed now.
Unavailable The sample cannot be removed.
The colors are different from those in the Test Result Monitor dialog box.
Icons The barcode box turns gray when a barcode error arises, or an icon
is displayed with the barcode number to prompt cautions.
Icon Name Sample status
Caution (yellow) This icon appears mainly when the barcode cannot be read.
Warning (red) This icon appears when the barcode number is different from the
one that should present at the cup (dispensing) position. This
warns you about the possibility of dispensing a wrong sample.
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6 USER INTERFACE
STAT Port
Temporary Change Use this dialog box to temporarily change the tests that are regis-
tered for each set.
Selection Release Click this button to cancel STAT Set Specification
Timer Off Click this button to cancel automatic start.
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6 USER INTERFACE
6.2.3 PRIME
In the PRIME Set window, you can configure settings for PRIME and execute it so that air
bubbles are removed from the pure water lines. Click EXECUTE to start the pumps of each
linr and they will operate the number of times you have specified to remove air bubbles. Exe-
cute PRIME 1 in the morning and prime is performed 5 times per line. If you wish to prime
each line for times other than 5, select PRIME 2 or 3 and specify the number of times.
PRIME Set
Save Click this button to save the settings that you have changed.
Cancel Click this button to terminate the function without executing it.
6.2.4 WASH
In the WASH Set window, you can wash the analyzer. Select WASH1, 2 or 3, place liquids in
the designated positions on the RTT1 and 2 trays and click EXECUTE. Normally, for washing
in the morning, select WASH 3 and rinse the analyzer. For washing in the evening, select
WASH 2, to wash the analyzer with a detergent and rinse. To rinse the analyzer, set pure water
in the RTT1 and 2 trays. To wash it with a detergent, set pure water and the alkali detergent
(REAGENT PROBE WASH-K) in the RTT1 and 2 trays.
Replace a liquid in the detergent position with REAGENT PROBE WASH-K (5%)
and wash the analyzer with it at least once a week (see p 1-4).
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6 USER INTERFACE
WASH Set
WASH 1 Select this button to wash all the probe lines (the initial wash takes approxi-
mately 14 minutes, plus an extra 20 minutes per additional wash).
WASH 2,3 Select this button to wash all probe lines and all reaction containers. (The ini-
tial wash takes approximately 27 minutes, plus an extra 12 minutes per addi-
tional wash.)
WASH 2 and WASH 3 are run the same way.
Cycle Select the number of washes.
CTT cup position, Container type Currently not available.
RTT1 bottle posi.0, Container Type Displays the position on the RTT1 tray
where you place the liquid for WASH and
the container type.
RTT2 bottle posi., Container Type Displays the position on the RTT2 tray where you
set the liquid for WASH and the container type.
Execute Click this button to start washing.
Save Click this button to only save the setting and terminate the function.
Cancel Click this button to terminate the function without changing the setting.
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6 USER INTERFACE
Request
Order Entry
6-9
6 USER INTERFACE
6-10
6 USER INTERFACE
6-11
6 USER INTERFACE
(Light blue+Black)
Rerun Currently dispensing.(When STT retest
Dispensing is specified.)
Pending Rerun (Do not take out sample), Rerun In process, or Complete (Rerun)
is displayed when you set auto rerun.
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6 USER INTERFACE
6.3.1c 3Review/Edit
You can check the measurement result in the Review/Edit window.
Review/Edit
Checking the measurement result
Routine smp. You can check the data of a routine sample and a STAT sample.
Today You can check the data for one week including the present day. As for
the data of the present day, do not forget to click the Save button for
each sample if you change the contents which can be overwritten. If
you do not click the button, the overwritten contents will not be saved.
・Glay Untested.
・Blue All assigned tests completed, including reruns.
・Yellow Analysis completed, including rerun tests (ticked in the R column
on the left list).
・Light blue Analysis completed with some untested tests.
・Pink In analysis.
Clicking the Order no. header displays an order test and its data on the right. For
the samples specified to be reanalyzed, an asterisk is placed in the R column and
sample volume (reanalysis conditions) is selected depending on the setting of the
analysis conditions. You can order reruns of samples that are not specified to be
reanalyzed by checking the R and the dispensing volume boxes of the sample listed
on the right hand of the headers by saving the settings.
R Displays an asterisk if the sample is specified to be reanalyzed.
Flag Data are flagged H, L, u, d, and with other flags.
Rerun val. Displays the data of the rerun value.
Prev val. Displays the previous values sent from the host computer system.
Dil.cond. Select the rerun condition.
・M An initial condition where a rerun is conducted based on the reaction
sample volume and the dilution condition set in the Analysis test condi-
tion setting section of the Analysis Parameters (Chemistry) window.
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6 USER INTERFACE
・D1-D4 Conduct a rerun based on the reaction sample volume and the redilution
condition set in the Reanalysis condition section of the Analysis Pa-
rameters (Chemistry) window.
Save
Click this button to save the changes to the data, the rerun order, and the dispensing vol-
ume of a sample for a rerun.
Update
Displays the latest information while the Review/Edit window is open. Data are not
shown in real time.
Disp search cond
Enter the details of a sample to be displayed on the display list on the left side.
Display conditions Tick Pending, Complete, Rerun Complete, Incomplete, and/or In
Process.
Samp.type Select Serum + Urine, Serum, or Urine.
Search conditions Includes Sample #, Comment1, and Comment2.
Correction Calc.
You can specify the range of a sample and make corrections on the measurement results
for each test in batch.
Print Report
Click this button to print data in the format you created in the Print Form Settings window
that was opened from the Setup window.
Host Transfer
Transfers the measurement results to the host computer in batch.
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6 USER INTERFACE
Date Displays the date of the past week including the present day.
Sample type Select a type from Routine smp., STAT.sample, Control smp.,
STD.sample (including reagent blank), Water Blank, or Detect.RV
chk.
Sample list Set Order no., Posi.no., or Sample.no of a sample to display tests ana-
lyzed in the sample in the Test name list window.
To display the reaction process of a control sample, select Control. smp. under
Sample type, and enter 001 or 201 in the Order no. box or PA001 or PB001 in the
Samp.no box. To display the reaction process of a standard sample, select STD
sample under Sample type and enter C0101 or M980101 in the Samp.no box.
UP, DOWN Displays the previous and the following samples to the test you
selected.
React.proc.data information Displays the details of data (see P 2-10)
Calc.results Displays the reaction process of measurements calculated in
main and subsidiary wavelengths.
M/S-WL Displays blue for the reaction process of a main wavelength
and red for that of a sub wavelength.
Aprox.curve Photometric points used in data calculation are displayed in
the reaction process.
Data List
Displays the absorbance of each photometric point.
Cuvette Blank
Displays the cuvette blank of a cuvette used in the reaction before and after it.
Scale change
Changes a scale of the X-axis and the Y-axis of the reaction process.
Create data file
Absorbance of each photometric point of the wavelength you selected is saved in the me-
dia.
Data Print
Prints the absorbance of each photometric point.
14WL monitor
Displays the reaction process of the fourteen wavelengths between 340 and 884nm.
Print Report
6-15
6 USER INTERFACE
6.3.1f Statistics
Perform the statistic calculation for the data analyzed.
Test Select
1. Routine/Priority/STAT samp.meas. To analyze routine samples, select this test.
2. Ordinary control samp. meas To analyze ordinary control samples, select this
test. Before selecting Temp.test at the start of an
analysis, select this test.
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6 USER INTERFACE
Test Select
6-17
6 USER INTERFACE
Sample Log
6-18
6 USER INTERFACE
Cup/Tube Assign
6-19
6 USER INTERFACE
6-20
6 USER INTERFACE
6.3.1l Correlation*
The Correlation window creates the correlation diagram of two different data or of measured
data and data you entered manually in the window.
Correlation
* Follow the instructions below when creating a new correlation diagram.
Register a name of the data in the Data regist. window, and select the file number you have
just registered from the top right of the Data search menu. Enter necessary data in the List
disp. window, click Save, and then click Return to create a correlation diagram.
You can create up to 100 correlation diagrams. A correlation diagram is printed as a hard copy
of the screen.
Data regist.
Registration list Displays a list of the correlation diagrams already created (en-
try numbers and registration names).
Entry no. Type a numerical value in the range from 1 to 100. Avoid any
numbers used in Registration list. (The registration number
refers to the numbers in the Registration list. in this win-
dow.)
Correlation range Specify the Order no. in the Order Entry list. You can select
up to 1000 pieces of data.
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6 USER INTERFACE
6.3.2 CALIBRATION
Calibration
6.3.2a View Calibration Curve
Displays the most recent calibration results.
You cannot save or edit except for in READY or WAIT mode.
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6 USER INTERFACE
Slider Bar
View Calibration Curve and Calibration Trace (Calibration History)
Calib.summary
Displays the calibration values used for the current operation.
When clicking the test name, the test calibration values appear in the column on the right.
Calib.summary
Multi-point calibration curve results cannot be printed. Perform Screen print to re-
tain the results.
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6 USER INTERFACE
Sample Select
6-24
6 USER INTERFACE
・MSTD...The Setting button displays Multi-STD Setting tests done from the Analytical Parame-
ter. You can enter the position to place the standard for configured tests as a
multi-point calibration curve (MSTD) from Calc.mthd in the Analytical Parame-
ter (Chemistry) window. (See P 3-6.)
Tray Number...Set the standard multi-point item in the STT. This is the number.
* The final concentration becomes approximately a straight line.
CTT set
Specify each CTT position (Cup/Tube Type) and enter Reps and Comment.
STT set
Specify the TT No.98, 99 containers for calibration (multi-standard) and enter Meas.times and
comment.
When using auto calibration it is necessary to set the 7.Auto Calibration meas.
(BLK) and 8.Auto Calibration meas. (STD) (also 4.Auto control meas. after calib)
from Calib.-Test Select. (see P6-16)
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6 USER INTERFACE
*
*: Displayed in Manager
QC
6.3.3a Daily Precision Control
■ X Chart
Each control of the data analysis appears as a graph for each test.
A graph appears in blue. If one of the data plots for a graph is out by +/-3SD, it appears in red.
Save...Click Save after omit (delete) operation is selected for each data. It can be used only in
READY or WAIT mode.
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6 USER INTERFACE
Save control data...The displayed control sample’s statistical data for the day (mean and fluctua-
tion width displayed in the QC List) is recorded in Daily QC in the
Control Data Registration window. (See P 3-10~11.)
Display order test...The display order for the X Chart.
Settings(S)–Setting of the order of display...Sets the display number of the X Chart. *When
you close this window, the same window as QC Cumulative appears. Click Yes in the Add
Daily to QC Cumulative data? window that appears. Next, click OK in the QC Cumulative
Calculation window that appears and record this data in QC Cumulative. (See P 1-7~8.)
■ QC List
When changing the X Chart to the QC List display, each control sample and the acquired data
for each test appear. (Ave. and SD can be saved as control values. See P 3-11.)
QC List
■ Control Data
When changing the X Chart to the Control Data, each control sample and the acquired data
for each test appear.
Specified test’s statistical data X Chart
Control Data
Data Display Section
6-28
6 USER INTERFACE
• Test...Displays the data for each test. Statistical information also appears.
• Omit...The data cannot be changed, however, when you click Omit the data appear in
red and after clicking Save the data are no longer reflected in the cumulative calcula-
tions.
• Overlap...Displays the graph for the checked controls.
6.3.3b QC Cumulative
Similar to the Daily Precision Control window.
■ X Chart
Displays in blue each control and each test for the last month including the current day in a graph. If
one of the data plots for a graph is out by ±4SD, it appears in red.
QC Cumulative
When confirming past data, change the data display period in Sys-
tem—Specification at date. The X-R chart, Control data, and QC List are displayed
for this configured period.
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6 USER INTERFACE
6.3.3c Real-Time QC
Two types of random control data are displayed for each analysis in the same graph.
■ X Chart
Decide on the number of graphs to be displayed in one window in Setting–Chart setting.
Real-Time QC
■ Twin-Plot
When changing from X Chart to Twin-Plot display, a maximum of 200 data plots are displayed.
Registration list edit
When unedited, decide on two control types and tests and decide on the display order in the
Real-Time QC window display order.
① Select the controls from A to Z to measure as Control 1 and Control 2. The
two control type’s common measured test appears in Test List.
② Click the test to highlight in blue, and then click Regist to add it to the Regist
Test. Real-Time QC Registration List
③ Shift the graph display order
UP or DOWN and click OK to
decide and create the graph.
Control 1, Control 2...Select two
control samples to perform
Twin-Plot.
Test List...Select the Twin-Plot test
to perform.
Regist Test...List of the Twin-Plot
display tests.
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6 USER INTERFACE
6-31
6 USER INTERFACE
QC Sample Definition
CTT Set
Specify each CTT position’s container and enter Replicatets and Comments.
AUTO Control
During the measurement of a routine sample, the control sample set in the CTT is automati-
cally measured at the configured test intervals.
Select and set from Auto Control (TOTAL TEST) or Auto Control (TEST). (Change the
settings in Setup–Setting System Parameters.)
*See the auto control measurement operation manual.
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6 USER INTERFACE
6.3.4 REAGENT
Reagent
6.3.4a Reagent Test Monitor
Displays the Remain Vol. (mL) and test times for R1, R2e, and R2 for each separate test. (See
Reagent P 3-3.)
• The remaining volume displayed in the window renews every 5 seconds.
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6 USER INTERFACE
Reset
The specified range for the remaining volume of a reagent resets when you click reset in
the event the reagent has become empty. You can continue to do analysis without hav-
ing to perform a remaining volume scan. (During the measurement, when the RPP re-
agent for the test has aspirated, the reagent’s remaining volume is newly displayed.)
Remain test
When the number of the tests remaining lowers the configured test number, the graph
display changes from green to yellow as well as test names. The initial setting is for 100.
This can be changed for each test. When the reagent becomes empty, its name appears
in red with the E symbol.
Reagent Moniter
Displays the reagent bottle’s liquid surface height in (cm) and the reagent’s remaining
volume (mL) for each RTT position.
When you click the name of each test, the position of the reagent for the test and
the number of tests remaining for each reagent appear.
Reagent Position
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6 USER INTERFACE
CTT Monitor
The sample container’s remainder and the reagent’s remaining volume (mL) for each position in
the CTT.
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6 USER INTERFACE
6-36
6 USER INTERFACE
6.3.5 MAINTENANCE
*: Displayed in manager
* *
Maintenance
System Monitor
During-operation system set
• Realtime monitor
Routine analysis/STAT analysis...Select the display and reprint for the Realtime
Monitor. (Normally, Standard or Conc. is used.) (See P 3-12.)
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6 USER INTERFACE
Variance value display...Select the variation value for the response process ab-
normality check. The variation value appears only for those
samples with a check flag that was added when selecting Dis-
play when there is a flag.
On-line...On-line selection. Select Do or Not do.
Pre-operation set
Chemistry...Specifies whether to cancel analysis (Operate/Cancel).
The ISE module only operates when canceling the analyzer.
ISE...Specifies whether to cancel the ISE module (Operate/Cancel)
Labo.Auto.Sys....Specifies whether to cancel the Rack Handler (option)
(Operate/Cancel)
Rack Handler...Specifies whether to detach the LAS (Laboratory Automation Sys-
tem) (Operate/Detach).
Clot Detect
Clot Detect...Avail./N.A. (SPP clot detection).
User
Maintenance
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6 USER INTERFACE
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6 USER INTERFACE
• Execute...The button to execute the unit operation according to the entered No.
Manual Operation
44.MUD1
45.MIX1
40.MIXR1
23.WUD
SPP
46.MWEV1
ELA07 16.SPPLR
MIX1 56.MUD2
17.SPPUD
57.MIX2
21.SPEV2
22.RRV 52.MIXR2
58.MWEV2
RPP2
RPP1 MIX2
2.STT/CTT 49.RPPLR2
37.RPPLR1
50.RPPUD2
38.RPPUD1
54.RPEV2-2
42.RPEV2-1
STAT
48.RTT2
47.RBC2 36.RTT1
35.RBC1
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6 USER INTERFACE
Manual Operation
Vacuum pump
41.RPEV1-1
61.VDP
20.SPEV1 53.RPEV1-2
1 Liquid Waste 2
71.LWP
(Back) Conditioner
19.SRWP 51.RP2
(Front) Cuvette wash
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6 USER INTERFACE
* Example: 17:SPPUD
・ Init....The button to arrange initialization for independent units. (SPP is on the ISE mod-
ule.)
・ Move...The button to order operations for units. A one step operation (A B, B C, C A) is
continuously executed. (For example: to stop the sample tube at the upper end in System
Specification Settings–Sample Container Specifications for SPPUD.)
・ Position...Specify the cuvette position and cup position number for the specified operation
of a related tray.
・ Unit...Specify the distance of movement (mm) for the probe related operation.
・ LLS-Action...According to the sample tube
number settings entered for specifying the opera-
tion of the probe that has the attached liquid sen-
sor, the probe lowers to the liquid surface and
stops. (System Specification Settings–Sample
Container Specifications) If there is no liquid in
the container, the probe lowers to the bottom of
the container and stops.
SPPUD
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Communication Monitor
6-43
6 USER INTERFACE
• STOP+R‐Enters STOP mode and an alarm sounds. Once data output is finished, it
stops in the READY mode.
• STOP+W‐Enters STOP mode and an alarm sounds. Once data output is finished, it
stops in the WAIT mode.
• Emergency Stop ‐ Everything is suspended.
When you want to confirm the details, double-click on the content and the Error Report De-
tails appear.
Error Report
Start
f
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6.3.6 SETUP
Setup
6.3.6a System Specification Settings
Use this window to enter the basic settings which will take effect after the next New Start. Sam-
ple Container Specifications and Reagent Bottle Specifications will take effect through the
INITIALIZE operation after saving the settings.
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6 USER INTERFACE
Analytical condition
Enter Reagent volume, Reagent diluent volume, Sample volume, stir (strong or weak),
Reaction Time and other settings.
For three-part reagent, concentrated reagent setting, urine setting, and reaction time
extension, see APPLICATIONS THREE PART REAGENT,” USING
CONCENTRATED REAGENTS, MEASURING URINE and PROLONGING
ROUND in the user’s guide.
• Analysis test condition setting・・・Conditions for sample dilution can be set for each
sample type.
Sub pram.#・・・1 - 3
Sub pram# 2 and 3 are used when extracting data from the same reaction with different
analytical conditions.
Sub analysis conditions
Enter the data in Name, Digits, M-wave.L., S-wave.L., Analy.mthd, Calc.mthd,
Qualit.judge, and other settings. The selection of Calc.mthd determines the availability
of the standard position of calibration and multi-standard. (See the user’s guide for de-
tails.)
• Real-time correct.form.・・・Apply calculated data into this formula to quickly correct
data.
• Reanalysis conditions・・・When reanalysis of data is specified, serum will be diluted by
this condition for reanalysis. Four dilution conditions can be specified in D1 to D4 for
each test. When you specify 2 or more conditions, enter the dilution ratios in ascending
order from D1 so that the lowest ratio is in D1. (See P 2-4 and pages following.)
• Rerun conditions set・・・Dilution conditions M and D1 to D4 can be selected for each
flag attached to data. (See P 2-4.).
• Flag setting・・・Whether to print flags or not.
• Normal value setting・・・Set normal values.
• Abnormal value setting・・・Set the limit H and L for abnormal values. (See P 2-3.)
Standards setting
Enter FV, BLK H / L, and STD H / L.
• Multi-STD setting・・・Sets the multipoint calibration curve.
• Error judge rate (vs.previous data)・・・If data are more than this setting (%) away
from the previous calibrated value, the data will be flagged with (Z). Do or Not do has
to be selected in Maint. – System Monitor – Error judge rate
(vs.previous data). (See P 2-11.)
Calculation method setting
Enter measurement detection points, Limit value, Variance (for linearity flag (*) judg-
ment), and the necessary settings for RRA and EPA, such as Blank(u)(d), Sample(u)(d)
(for RRA), Reabsorb(u)(d) (for EPA), Prozone setting, and others. (See P 2-7 to 2-9.)
CTT Set
Enter the CTT settings such as Replicates of calibrators, dedicated diluents, and control
samples, Cup/Tube type, and Comments.
Copy
Use this button to copy other Analytical Parameters.
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6 USER INTERFACE
Use it when you want to replace all the settings for the Analysis condition number cur-
rently displayed with the settings for other Analysis condition numbers.
Parameter Check
Use this button to check whether there is any errors or inconsistencies in the settings.
• Anal.cond # & test name・・・Displayed in the order entered in the Analytical Parameter
(Chemistry) window.
• System test #・・・Analysis will be performed in this order.
• R-Code・・・Enter the code number when reagents are barcoded.
• Position・・・Enter the position of R1 (RTT1), R2e or R2 (RTT2).
Analysis order
Use this button when you want to change the analysis order later in System test #.
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6 USER INTERFACE
• Cond.no.・・・If you enter a number here, the Test name appears automatically. You can
edit the Test name here.
• <SP and DEL buttons・・・Do not use these buttons because they will change the Proc-
essing test order.
• Processing test Order・・・Displays the test list.
• Print Monitor Order・・・The order of the tests for RealTime Monitor and Batch print.
The order can be changed using the Up and Down buttons.
Process Sequence
6-50
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6-51
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Ratio Parameters
6-52
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Analysis order
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Contaminating Contaminated
No. Probe Reagent Reagent Inf.effect Detergent no.
Test Test
1 RPP1 LAP R1 CRP R1 1 (903) Pure water
2 RPP2 LAP R2 CRP R2 1 (908)Pure water
(901) REAGENT
3 RPP1 GPT R1 LDH R1 12
PROBE WASH 1
(906) REAGENT
4 RPP2 GPT R2 R2e 12
LDH PROBE WASH 1
(902) REAGENT
5 RPP1 TCHO R1 FCHO R1 999
PROBE WASH 2
(907) REAGENT
6 RPP2 TCHO R2 FCHO R2 999
PROBE WASH 2
(902) REAGENT
7 RPP1 R1 Fe R1 999 (903) Pure water
PROBE WASH 2
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6 USER INTERFACE
(907) REAGENT
8 RPP2 R2e Fe R2 999 (908) Pure water
PROBE WASH 2
(907) REAGENT
9 RPP2 R2 Fe R2 999 (908) Pure water
PROBE WASH 2
(902) REAGENT
10 RPP1 A R1 B R1 999
PROBE WASH 2
(907) REAGENT
11 RPP2 A R2e B R2e 999
PROBE WASH 2
(902) REAGENT (904) REAGENT
12 RPP1 R1 B R1 999
PROBE WASH 2 PROBE WASH 2
(907) REAGENT (909) REAGENT
13 RPP2 R2e B R2e 999
PROBE WASH 2 PROBE WASH 2
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reaction cuvette
… TP ALPCREALT AST … Previous test
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6 USER INTERFACE
⑤ Also set the REAGENT PROBE WASH effect (the REAGENT PROBE WASH
effect can be avoided with pure water. Specify the contaminated test).
Detergent no.
No. Contaminating test Contaminated test
RPP1 RPP2
1 LAP CRP (903) Pure water (908) Pure water
(901) REAGENT (906) REAGENT
2 GPT (900)All test
PROBE WASH 1 PROBE WASH 1
(902) REAGENT (907) REAGENT
3 TCHO (900)All test
PROBE WASH 2 PROBE WASH 2
4 Detergent Fe (903) Pure water (908) Pure water
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6 USER INTERFACE
On-Line Set
Set Test
Enter Batch, Real, Qual, and Code numbers for each test.
Loop back test
This setting is for service personnel.
Data Clean Set
Data Clean check is a function to detect abnormal data and the mix-up of samples before
transmitting the data to the inspection system (host computer). It compares the obtained
results with the previous values sent from the host computer to analyzer unit, and only the
correct results are sent to the host computer.
In Data Clean Set, you can perform 5 checks per sample for each combination of sample
type (serum or urine) and method (real-time online or batch online). The actual check
takes place when data are transmitted online to the host computer. The check result is
saved by Request – Review/Edit – Transfer Result. If a sample is determined to have
errors in the check, it can be suspended from transmission to the host computer (tempo-
rary retention).
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6-60
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Carryover Setting
• Setup No.・・・Up to 10 logics can be set.
• Carryover test・・・Specify the test that needs a carryover check.
• Assay Judgment Value (Conc.)・・・Enter the threshold value for the judgment.
• Judgment Decision・・・Select Above or equal to or Below or equal to for Assay Judg-
ment Value.
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6 USER INTERFACE
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7
7.1 HbA1c................................................................................................................. 7-1
7.1.1 General ....................................................................................................... 7-1
7.1.2 Measuring Method ..................................................................................... 7-1
7.1.3 Specifications ............................................................................................. 7-1
7.1.4 Analysis ...................................................................................................... 7-2
7.1.5 Setting......................................................................................................... 7-2
7.1.5a HbA1c Setting..................................................................................... 7-2
7.1.5b Setting Dilution Conditions................................................................. 7-3
7.1.5c Hb Setting ........................................................................................... 7-4
7.1.5d Sampling Position Setting ................................................................... 7-4
7.1.5e HbA1c% Setting............................................................................... 7-5
7.1.6 Maintenance ............................................................................................... 7-6
7.2 NEW SAMPLE CONTAINER SETTING ......................................................... 7-7
7.2.1 Measure the shape of the sample container. ............................................... 7-7
7.2.2 Set the shape of the measured sample container. ....................................... 7-7
7.2.3 Execute INITIALIZE. ................................................................................ 7-8
7.2.4 Check the shape of the container................................................................ 7-8
7.3 ALARM TABLES ............................................................................................ 7-10
7.3.1 When an alarm sounds ............................................................................. 7-10
7.3.2 Explanation of the Error Report window ................................................. 7-11
7.3.3 General method of reading alarm descriptions......................................... 7-11
7.3.4 Safety No. Table ....................................................................................... 7-12
7.4 DETERGENT DESCRIPTION........................................................................ 7-26
7 OTHERS MATERIALS
7.1 HbA1c
7.1.1 General
JCA-BM6010/C enables you to analyze for a blood cell component (HbA1c) and for plasma
components (such as Glu or 1.5AG) simultaneously by setting the sampling positions for each
test .
Measure HbA1c
7.1.3 Specifications
Cleaning the SPP probe:
Aspiration from [Top]: 15 mm away from the tip of the probe
Aspiration from [Bottom]: 60 mm away from the tip of the probe
Capacity:
Max. 800 tests/hour
Analysis of blood cell components requires the use of a hemolysis sample that was created
with the reaction cuvette mounted to the analyzer. This hemolysis sample requires the op-
eration time for one test. Analysis of one test for the blood cell component requires the op-
eration time for two tests. Therefore, operation of the analyzer for only the analysis of blood
cell components enables 400 tests per hour. If, for example, the plasma component analysis
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7 OTHERS MATERIALS
(with no hemolysis reaction) and blood cell component analysis (with hemolysis reaction)
are respectively regarded as one test per sample, operation with this combination enables
533 tests per hour (Analysis for the two tests will take place in the operation time for three
tests).
7.1.4 Analysis
The basic operation is the same as for BM6010/C.
When you perform measurement for a test (such as HbA1c) whose Sampling
position setting is set to Bottom, keep the liquid height of the sample in the
container no higher than 60 mm. For cleansing the SPP probe in the wash port, the
cleansing height must reach up to 60 mm above the tip.
7.1.5 Setting
Click Setup – Analytical Parameters (Chemistry) for the sample dilution condition set-
ting or the sampling position setting. (manager)
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7 OTHERS MATERIALS
Note:
• Dilution specification-
Not do: Conducts measurement with the analysis conditions in Serum.
Do: Conducts measurement with analysis condition other than that set in Serum.
• Undiluted sample volume: Enter the amount of the sample to be used for analy-
sis.
• Dilution method: Choose No dilution or With dilution. With dilution refers to the
dilution method using RRV cuvettes.You need to set Undiluted sample volume,
Diluent volume, Diluent position, and Diluent volume from RPP.
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7 OTHERS MATERIALS
7.1.5c Hb Setting
Change Sub Param. for HbA1c to 2 ,and set Sub-analy.conditions to Hb.
HbA1c
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7 OTHERS MATERIALS
As for Standards and Controls ,set to Top. Ordinary samples that have already had diluted
hemolysis performed are registered as STAT, and Top is specified as the sampling position
so that dilution by the analyzer will not be performed. See (2) in Setting Dilution condi-
tions above.)
* In the Sampling Position Setting window, under Gen/STAT/Priority and Con-
trol(A-M/N-Z), before slash “/” is the setting for the upper row and after slash “/” is the
setting for the lower row.
Height Setting
Specify the distance from the bottom of the container when Bottom is specified as
Sampling position.
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7 OTHERS MATERIALS
7.1.6 Maintenance
Cleaning a probe and Checking a location
After finishing the HbA1c analysis each day, move the probe of SPP to a position where you
can easily wipe it, and then use pure water to wipe the probe.
1. Move the SPP probe to a location where you can easily wipe it, and carefully wipe the out-
side of the probe upward using gauze or similar materials soaked with pure water.
2. Click INITIALIZE so that the analyzer will enter the READY state.Observe the DPP’s
wash port from above, and make sure that the probe does not touch the wash port or the
washing water retaining plate when the probe moves downward.
3. Double-clicking 17.SPPUD in the Maint. – Manual Operation window opens the win-
dow for instructing the SPPUD operations.
When you click the Move button,SPP moves downward at the wash port. At this time
check that SPP lowers to the bottom without touching the wash port or the washing water
retaining plate. Clicking the Move button again will raise SPP. (This check is required be-
cause the SPP’s probe moves up and down at the wash port when SPP is being washed.)
4. Click Init. in this SPPUD window to raise it to the original position.
(See 2. Inspecting and cleaning the tip of probes on page P 4-4.)
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7 OTHERS MATERIALS
7-7
7 OTHERS MATERIALS
(8)
(9)
⑧ Enter the registration number for the new sample container in the boxes to the
right of Move and LLS-Action.
⑨ Confirm that the sample container is not in position 1 of STT, and then click
Move. SPP lowers to the top position according to the Sample Container
7-8
7 OTHERS MATERIALS
⑪ Manually rotate STT so that SPP moves to right above position 1 of STT.
Confirm that there is no sample container there. Check the box to the right of
LLS-Action to see that the registration number for the new sample container
is entered, and then click LLS-Action. SPP lowers to the bottom of the Sam-
ple container setting (h3 setting). Confirm that SPP does not touch the bottom
of the container during the operation.
⑫ Click Init. to raise SPP to the top.
⑬ Manually operating STT, check that SPP is almost above the sample con-
tainer set to position 2, and then click LLS-Action. SPP lowers to the bottom
of the Sample container setting (h3 setting).
⑭ Then, manually raise the sample container set to position 2 and confirm that
there is a little room.
⑮ Click Init. to raise SPP to the top.
⑯ Click Exit to close the Manual Operation window.
⑰ Execute INITIALIZE to confirm that the analyzer enters the READY state.
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7 OTHERS MATERIALS
MAIN switch
ALARM
② When you click ALARM, the Error Report window appears, and the alarm
message disappears.
[Screen print]button
③ Description of the device status is displayed in the Contents column. The lat-
est information is given at the top.
When WARNING appears in the Measures column, the alarm buzzer sounds. Check
the details of the alarm.
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7 OTHERS MATERIALS
If an analysis has been performed, check Samp.ID and Test Name that are displayed.
④ Double-clicking the content of an alarm message opens the Error Report De-
tails window to check the details.
* Several lines of errors may appear at the same time. In that case, if the time is the
same, usually the one displayed at the bottom refers to the first cause of the error.
Check the content.
⑤ Check the following content and, if necessary, contact your JEOL service
center.
(You can print by clicking Screen print in System(S) at top left of the window.)
a. Date/time of the alarm and what was taking place at the time of the alarm.
b. Safe.No (described later)
c. Check the content and details
d. Identify the failed unit (not displayed in some cases).
Latest info.: This window is not a Realtime Monitor, so close the window and open it
again. Alternatively, click Latest info.
Print: Prints the content in the specified number range. (Or Screen print)
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7 OTHERS MATERIALS
SPP lowered and stopped at a positon that was too high or too low.
Cause: The volume of ISE Dil.bowl in WARNING is abnormal.
Upon double-clicking, "Buffer Height:HIGH" appears which indicates that the volume is
too high.
As a result of this problem, after the transition to STOP due to "Remaining fluid in ISE
bowl error," SPP stopped its operation.
Consequently a unit operation timeover occurred, thereby the analyzer stopped in the
WAIT state.
7-12
7 OTHERS MATERIALS
7-13
7 OTHERS MATERIALS
tains invalid test no. Check the test number displayed in the error report details.
3061, No problem in par- Check the settings by clicking Maint. –Communication Monitor.
3062 ticular
3503 Error in the text message from the host. Check by clicking
to Maint.–Communication Monitor.
3516
ISE MIX-1
MIX
M IXE
室温恒温
SPP 室
Reaction
Reaction 温
carousel 恒
MIX-2 BPEV
B PE
STT 温 WB DPEV
D PE
槽
脱 気 ユニッ
Air removal unit
RPP-2 RPP-1 脱
気
STATport ユ DBP
P BP
DP
RTT-2 RTT-1 ニ
ッ
ト
4079 Restart, and if recovery fails, contact your JEOL service center.
to
4081
4082 ISE thermistor error Thermistor (temperature element) disconnected wire, defect, or re-
moved connector. Refix it.
4083 Same as for 4079
4091 ISE Calibration Slope value is outside the range of 38 to 65.
slope error
4092 ISE Calibration Sample-buffer value is abnormal.
range error
4093 Calibration High Variation of sample-buffer value is too large. Failed to fall into the
STD error range even after 8 measurements.
4094 Calibration Low Variation of sample-buffer value is too large. Failed to fall into the
STD error range even after 8 measurements.
In the case of the above 4 errors, use a new standard solution to per-
7-14
7 OTHERS MATERIALS
7-15
7 OTHERS MATERIALS
4246 No ISE calibration Analysis started with no electrolyte calibration performed or with data
data erased.
Execute calibration.
4252 ISE no sample No sample is placed. Or the sample is empty.
(Sample analysis) Check if the cup is placed incorrectly or if the amount of the sample is
insufficient.
4253 ISE no calibration Standard solution is not placed, or the cup is empty.
sample (calibration) Check if the cup is placed incorrectly or if the amount of the standard
solution is insufficient.
4254 ISE buffer height See 4097.
error
4255 Execute INITIALIZE. If the same error occurs, contact your JEOL
to service center.
4256
4257 ISE calibration See 4092.
range error
4258 Execute INITIALIZE. If the same error occurs again, contact your
to JEOL service center.
4265
4266 See 4091 to 4097.
to
4270
4271 ISE calibration cor- Calibration error. Execute calibration again.
to rection data are in- If the electrode is old, replace it.
4272 correct
4273 ISE calibration dilu-
Dilution factor in the calibration result is abnormal.
tion factor error After performing maintenance, perform the CV check, and then repeat
calibration.
4274 Transmitted ISE Check the applicable columns above.
to calibration contain
4277 data error
Example: 5034 RRV INIT during starting and SPPUD is IN0 OFF.
Explanation: When RRV attempted to perform the INITIALIZE operation, the ver-
tical operation of SPP was poor, resulting in an error.
Action: Lubricate the shaft with oil for the smooth vertical operation of SPP.
If the situation is not improved, contact your JEOL service center.
If the error explanation ends with one of the following, the operation of the unit
just described is improper.
① In xxxx, IN # OFF for MUD1 => The vertical operation of MIX1 is improper.
7-16
7 OTHERS MATERIALS
② In xxxx, ENC pos undefined for RPPLR 1 => The horizontal operation of
RPP1 is improper.
③ In xxxx, NOT ENC (or Internal) pos # for STT => The STT operation is im-
proper.
④ In xxxx, MIXR2 is under operation or in xxxx, RPEV1_2 is OFF =>
MIX2 rotation improper. RPEV1-2 (electromagnetic valve) operation improper
RPP2 SPP
RPP1 RRV
WUD
MIX2
SPP STT/CTT
RPP2 RPP1
Vertical
Apply oil movement
onto shaft MUD1
MUD2
② If the pump (SRWP, RP1, RP2) operation is improper, perform the shutdown
operation once, remove the pump fixing screw, and pull the pump a little to-
ward you. Rotate the motor shaft in the direction of the arrow (see Fig. below)
to move the plunger, and restore the unit to the original position. Then restart
and perform INITIALIZE.
7-17
7 OTHERS MATERIALS
[Pump]
③ For units other than the above, perform the shutdown operation once, and re-
start and perform INITIALIZE.
Tight fit
Caution
There shall be no gap between
stopper and terminal 1
7-18
7 OTHERS MATERIALS
connector
③ Improper contact with the LLS connector in the
probe cover (remove/insert the connector)
6140 Diluent LOW The special diluent (within CTT) has nearly run out.
6141 Diluent EMPTY The special diluent (within CTT) has run out.
6142 RPP1 probe detected re- The mounting of the probe is loosened.
agent above wedge
6143 RPP1 reagent EMPTY The reagent has run out.
6144 RPP1 sensor full stroke Reagent has been left unattended or has run out.
error
6145 RPP1 Detergent LOW REAGENT PROBE WASH, water, and detergent have nearly
run out. (RTT1)
6146 RPP1 Detergent EMPTY REAGENT PROBE WASH, water, and detergent have run out.
(RTT1)
6147 RPP2 probe detected re- The mounting of the probe is loosened.
agent above wedge
6148 RPP2 Detergent EMPTY Reagent has run out.
6149 RPP2 probe detected no Reagent has been left unattended or has run out.
reagent
6150 RTT2 Detergent LOW REAGENT PROBE WASH, water, and detergent have nearly
run out. (RTT2)
6151 RTT2 Detergent EMPTY REAGENT PROBE WASH, water, and detergent have run out.
(RTT2)
6173 SPP sensed ISE buffer The volume of the ISE bowl is abnormal (too high or too low).
height error Check the remaining amount of the buffer bottle and check for
solution leakage around the electrode.
6177 System error The state of the sensor is poor when the probe is not touching
(LLS status error) anything.
The probe is dirty, or the connector has poor contact, or the
sensor is defective.
Check if detergent has been supplied properly.
6178 Probe did not detect wa- Cleansing of the probe tip at the wash port
ter at wash port is insufficient.
Check in the same way as above.
6202 System error REAGENT PROBE WASH, water, and detergent have run out.
(RPP1 sensor full stroke (RTT1)
error)
6203 System error REAGENT PROBE WASH, water, and detergent have run out.
(RPP2 sensor full stroke (RTT2)
error)
6204 No rack sample The sample has not reached the dispense position.
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7 OTHERS MATERIALS
6205 LAS/URH Sample ID The sample has not reached the dispense position.
communication error
6207 DWUD nozzle sensor WV Nozzle of DWUD hit the cuvette and did not come down.
error
6208 WUD nozzle sensor error WV Nozzle of WUD hit the cuvette and did not come down.
6222 Probe clash detected The probe hit the bottom of the sample container.
6227 LAS/URH Sample ID Communication text message error between BM and LAS
communication error
6230 Arrival Sample ID Information about the dispense sample ID was abnormal when
pointer abnormal dispensing the rack sample.
6238 The rotational speed is The number of back-forth mixing operations of the MIX1 unit
abnormal of MIX1 was outside the specified value range.
6239 The rotational speed is The number of rotational mixing operations of the MIX1 unit
abnormal of MIXR1 was outside the specified value range.
9240 The rotational speed is The number of back-forth mixing operations of the MIX2 unit
abnormal of MIX2 was outside the specified value range.
6241 The rotational speed is The number of rotational mixing operations of the MIX2 unit
abnormal of MIX2R was outside the specified value range.
* For the above errors of the MIX unit, contact your JEOL service center.
6242 Internal Special function A conflict occurred in the internal program that operates the
abnormal unit.
6247 RPP1 liquid surface veri- Sample tube has come off the solution surface even though R1
fication error (liquid sur- is being aspirated.
face separation)
6250 RPP2 liquid surface veri- Sample tube has come off the solution surface even though R2e
fication error (liquid sur- is being aspirated.
face separation)
6251 RPP2 liquid surface veri- When the probe stopped on the solution surface, its sensitivity
fication error (liquid level did not reach the level sufficient to recognize the solution sur-
sensor signal did not face.
reach
6252
6255 Clot Parameter error This is a sensor that checks the pressure inside SPP and detects
to clogging.
6289 ・Related to clot-A Check whether the pressure has returned to the atmospheric
pressure in the wash port when probe cleansing (proble wash-
ing) is finished.
* Possibility of clogging is high. Replace the SPP probe.
・Related to clot-B Check the pressure immediately before sample aspiration.
・Related to clot-C Check the pressure at probe cleansing (probe washing).
・Related to clot-E Checks whether the sensor functions immediately after starting
from READY.
* In the case of B, C, or E above, the sensor may be defective.
Contact your JEOL service center.
・Related to clot-D Check the pressure to see if a foreign matter was aspirated after
sample aspiration.
* It is possible that fibrin has been educed in the sample.
Check the sample and the measurement data.
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7 OTHERS MATERIALS
* If no clot error occurs in the next sample even though this er-
ror appears, clogging has been deleted with reverse cleansing
(probe washing).
* For other clot-related errors, contact your JEOL service center.
6300 SPP liquid surface veri-
to fication error
6302
6301 (liquid surface separa- Sample tube has come off the solution surface even while a
tion) sample is being aspirated.
6302 (liquid level sensor signal When the probe stopped on the solution surface, its sensitivity
did not reach the thresh- did not reach the level sufficient to recognize the solution sur-
old) face.
6303 Diluent Bottle will be
changed.
6304 0 time of the second
processing did not end in
regulated time.
6304 STAT-related
to
6322
6323
to
6329
6331 Sample carryover wash-
ing - SPP sensor upper
limit error
6332 Sample carryover deter-
gent shortage
6333 The sample carryover
detergent emptied
6334 Sample carryover wash-
ing - SPP full stroke error
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No.9080
Vacuum gause Pressure gause
For ISE LWP filter For LWP
9004 to Detergent, Cuvette condi- Check the amount remaining in detergent bottle and add
9006 tioner, ACUR, bottle in- detergent.
sufficient
9007 Pump chassis lower Leak The liqiud leakage sensor at the rear of the pump de-
tected leakage.
Check the location of the liquid leakage and take action.
For leakage, see No.9025.
9008 B1200 electric board 24V
power failure
9009 Abnormal of temperature
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of B1200 chassis
9010 RRB liquid surface level Level of incubation bath oil under reaction cuvettes de-
LOW creased or increased.
9011 RRB liquid surface level Check the detergent volume of the incubation bath oil
HIGH (for refill) tank within the detergent container.
9012 Logic is the RRB liquid There is a conflict between the two sensors above.
surface sensor abnormal.
STT/CTT Tray
Wash port
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9045
ISE WUD MIX1
<Rear view>
9048,9076 9027,9047
SPP ,9045
RRV
9025
MIX2
STT/CTT
RPP2 9026
RPP1 Incubation
bath
STATport tem-prema
RTT2 RTT1 ture
VDP
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7 OTHERS MATERIALS
7-25
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*
Default Setting(ISE Setting):User can change
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■ OTHER
No Part Name Part Number Picture Description
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