CHAPTER 6

CELL NUCLEAR DIVISION

Paper 1 (Multiple choices)

1. The diagram shows chromosomes in a nucleus. D
What are Y and Z?

2. The diagram shoes chromosomes taken from the nucleus of a cell. A

Which diagram represents a pair of homologous chromosomes?

3. Chromosome telomeres promote DNA replication and are not completely replaced during mitosis. A
A substance X is known that completely replaces telomeres during mitosis.
What will be the effect of growing a cell culture with and without substance X?

4. What is a correct description of the centrioles, nuclear envelope and spindle during mitosis in animal C
cells?

5. What occurs in anaphase of mitosis? C

A chromatids line up on the equator of the cell
B chromatids reach the poles of the spindle
C chromatids separate and move to opposite poles
D chromatids start to coil up and become visible
6. Which structure organises spindle formation during mitosis in animal cells? A
A centriole B centromere C nucleolus D nucleus
7. Which processes involve mitosis? B
A growth, reduction division and asexual reproduction
B growth, repair and asexual reproduction
C growth, repair and semi-conservative replication
D repair, reduction division and asexual reproduction
8. The diagram shows the mitotic cell cycle. B
When radioactive nucleotides are supplied to dividing cells, at which point will they be incorporated
into the chromosomes?

9. The diagram shows chromosomes at metaphase of mitosis. B

What are the diploid and haploid numbers for this species?

10. The diagram shows a cell of an organism formed by reduction division. C

What is the diploid number for this organism?

A 10
B 20
C 40
D 46

11. Which are features of nuclear division by mitosis? C

1 forms cells of equal size to the parent cell
2 forms genetically identical cells
3 semi-conservative replication of DNA
A 1 and 2 only B 2 and 3 only C 2 only D 1, 2 and 3
12. A diploid nucleus in a species of fruit fly has 8 chromosomes. C
How many DNA molecules are present in the nucleus at the end of interphase?
A4 B8 C 16 D 32
13. To which of the processes shown does mitosis make a contribution? A

14. Each of the following events takes place during mitosis. D

1 centromeres divide
2 chromatids move to opposite poles of the cell
3 chromosomes line up along the equator of the spindle
4 chromosomes uncoil
5 two chromatids are joined by a centromere
In which order do the events take place?

15. During which stage of the mitotic cell cycle is DNA replicated? B
A anaphase B interphase C prophase D telophase
16. What are the conditions in a human cell just before the cell enters prophase? C

17. Which statement describes events during interphase of the mitotic cell cycle? B
A Chromatids are pulled apart by spindle fibres.
B Chromosomes are replicated ready for the next division.
C Chromosomes line up on the equator of the spindle.
D Chromosomes start to coil, becoming shorter and fatter.
18. The graph represents the changes in D
the quantity of DNA present in one
nucleus at different
stages in the life cycle.

Which stage takes place at X?

A interphase
B metaphase
C prophase
D telophase
19. The diagram shows the chromosomes of a cell at late prophase of mitosis. A

What will be the appearance of the products of this cell division as they enter prophase of their next
division?

20. The graph shows three measurements obtained following metaphase of mitosis. A

What measurements do the curves represent?

distance / µm

21. Colchicine is a chemical that stops chromatids from separating during mitosis. B
Which phase will the cell reach and then stop dividing?
A anaphase B interphase C prophase D telophase
22. Which statement describes a cell that is capable of reproduction and belonging to a haploid D
organism?
A It has chromosomes that contain one polynucleotide chain.
B It is capable of carrying out a reduction division to form gametes.
C It possesses two copies of each gene as a result of fertilisation.
D It will undergo cell division by mitosis during asexual reproduction.
23. Which of the following is true of cancer? C
A Each mitotic division produces more than two daughter cells.
B Mitosis has stopped.
C Mitosis is uncontrolled.
D Mitosis results in cells with variable numbers of chromosomes.
24. Cancer cells divide out of control, forming tumours. B
Which statement describes the difference between a cancer cell and a normal cell?
A Cancer cells do not undergo cytokinesis. C Cancer cells do not have metaphase.
B Cancer cells have a shorter interphase. D Only cancer cells have mutated DNA.
25. Human cells contain 46 chromosomes.
The diagram shows a human cell in prophase of mitosis (cell 1) and daughter cells just after
telophase (cells 2 and 3)

How many DNA molecules are there in the nucleus of cell 1 and cell 2?