Immunology

Innate Immunity and Inflammation

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summarize the key concepts; you should save these
notes and review them. Use this document as an
outline for your note-taking. You can fill in the fields
on this interactive PDF digitally or print it out and
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Key Terms
These are the key terms and concepts covered in this lesson. After you have
learned a term, take a moment to write out your own explanation of the term.

Adhesion molecules

Cytokines

Circulating leukocytes

Dendritic cells

Endothelial cells

Innate immune receptors

Innate immunity

Macrophages

Immunology
Innate Immunity and Inflammation
Mast cells

Microbes

Monocytes

Neutrophils

Phagocytosis

Tissue-resident sentinel cells

Immunology
Innate Immunity and Inflammation
Concept Video Notes
Use the space below to jot down key points for each concept video. Attempt
to make connections between the concepts explained in these videos and
others already covered in the course. Are you unsure about any of the content?

Cells Important for Inflammation

Response of Sentinel Cells

Response of Blood Cells

Formation of Pus

Immunology
Innate Immunity and Inflammation
Learning Objectives
After you have completed the lesson, go through the learning objectives again.
Are you able to fill in a complete response to each learning objective?

1) Identify the main types of leukocytes that contribute to acute inflammation.

2) Contrast the functions of the two main types of phagocytic immune cells - neutrophils and macrophages.

3) Explain the role of tissue-resident sentinel cells in innate immunity.

4) Recall how innate immune receptors and cytokines contribute to inflammation.

5) Describe the leukocyte-endothelial interactions that lead to leukocyte recruitment into inflamed tissue.

6) Explain the steps taken by the immune system to respond to and eliminate a microbe that has breached an epithelial barrier.

Immunology
Innate Immunity and Inflammation
Summary Figure
Some of the steps in the inflammatory process are shown below. Can you identify and
number each step?

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Immunology
Innate Immunity and Inflammation