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Hearing
The auditory sense organ.
• organ of Corti:
- within the snail-shaped cochlea of the inner ear
- formed by the above cells/structures
Human Organ of Corti
• One theory:
- a Ca2+ regulated motor such as a myosin ATPase climbs
along actin filaments in the stereocilium:
l actively resets the tension in the transduction spring
Box B Adaptation
• during sustained depolarization:
- Ca2+ enters through the transduction channel, along with K+
- Ca2+ then causes the motor to spend a greater fraction of its
time unbound from the actin:
l resulting in slippage of the spring down the side of the stereocilium