GENERIC/ ACTIONS INDICATION DOSAGE CONTRAINDICATIONS ADVERSE EFFECT NURSING

BRAND/ INTERVENTION
Classification
Haloperidol • Alters the •Organic 2.5mg OD • seizure disorder •CNS: extrapyramidal • Assess mental status
(antipsychotic) effects of Psychoses • glaucoma symptom such as muscle prior to and periodically
dopamine in • elderly clients rigidity or spasm, shuffling during therapy.
the CNS • acute psychotic gait, posture leaning • Monitor BP and pulse
symptoms forward, drooling, masklike prior to and frequently
• Also has facial appearance, during the period of
anticholinergic • Relieve dysphagia, akathisia, dosage adjustment.
and alpha- hallucinations, tardive dyskinesia, May cause QT interval
adrenergic delusions, headache, seizures. changes on ECG.
blocking disorganized •CV: tachycardia, • Observe patient
activity. thinking arrhythmias, hypertension, carefully when
orthostatic hypertension. administering
• Diminished • severe anxiety •EENT: blurred vision, medication, to ensure
signs and glaucoma that medication is
symptoms of • seizures • GI: dry mouth, anorexia, actually taken and not
psychoses nausea, vomiting, hoarded.
constipation, diarrhea, •Monitor I&O ratios
weight gain. and daily eight. Assess
• GU: urinary frequency, patient for signs and
urine retention, impotence, symptoms of
enuresis, amenorrhea, dehydration.
gynecomastia • Monitor for
• Hematologic: anemia, development of
leucopenia, agranulocytosis neuroleptic malignant
• Skin: rash, dermatitis, syndrome (fever,
phtosensitivity respiratory distress,
tachycardia, seizures,
diaphoresis,
hypertension or
hypotension, pallor,
tiredness, severe
muscle stiffness, loss of
bladder control. Report
symptoms immediately.
May also cause
leukocytosis, elevated
liver function tests,
elevated CPK.
• Advise patient to take
medication as directed.
Take missed doses as
soon as remembered,
witih remaining doses
evenly spaced through
out the day. May
require several weeks
to obtain desired
effects. Do not increase
dose or discontinue
medication without
consulting health care
professional. Abrupt
withdrawal may cause
dizziness, nausea,
vomiting, GI upset,
trembling, or
uncontrolled
movements of mouth,
tongue or jaw.
 GENERIC/ ACTIONS INDICATION DOSAGE CONTRAINDICATIONS ADVERSE EFFECT NURSING
BRAND/ INTERVENTION
Classification
Ziproc Interfere with patients who fail 50mg BID History of drug-induced Most commonly,  Assess neurologic
(Antipsychotic) dopamine binding in to respond to or AM,PM neutropenia/agranulocy dizziness & fatigue. and psychiatric
the limbic system of experience tosis or w/ Other CNS reactions status
CNS, with affinity for severe myeloproliferative include seizures,  Provide chewing
dopamine receptors. extrapyramidal disorders; alcoholic & dizziness & gum or ice chips for
May antagonize side effects w/ toxic psychoses, drug headache. the client to suck to
adrenergic,cholinergic classical intoxication, comatose Extrapyramidal relieve dryness of
, histaminergic, and antipsychotics. conditions & other symptoms mainly mucosa.
serotonergic forms of severe CNS tremor, akathisia &  provide for patients
receptors. depression; severe rigidity. Dry mouth, safety during
hepatic & renal sweating & temp episodes of
impairment. Pregnancy regulation dizziness
& lactation. disturbance have  monitor vital signs
been reported. before and after
Tachycardia, postural administering
hypotension esp in medication.
initial wk of  Increase oral fluid
treatment. Nausea, intake and
vomiting & encourage the
constipation may inclusion of
occur. sufficient roughage,
fresh fruits,
vegetables and
whole grain
products in the diet
 Monitor ECG and
liver function test
results
 Instruct patient to
allow orally
disintegrating tablet
 to dissolve in the
mouth.
 Monitor WBC count
weekly for the first
6 mos of therapy.

GENERIC/ ACTIONS INDICATION DOSAGE CONTRAINDICATIONS ADVERSE EFFECT NURSING

BRAND INTERVENTION
Lithium Alteration of To treat bipolar 450mg half Liver and renal disease, severe Headache,  Assess neurologic
Carbonate ion transport manic-depressive tab TID cardiovascular disease, severe lethargy, and psychiatric
(Antidepressant) in muscle and psychosis, manic dehydration, brain tumor drowsiness, status
nerve cells; episodes damage, sodium depletion dizziness, tremors,  Monitor lithium
increased slurred speech, blood level, WBC
receptor dry mouth, count
sensitivity to anorexia,  Assess
serotonin. vomiting, cardiovascular
diarrhea, polyuria, status regularly
hypotension,  Monitor vital signs
abdominal pain,  Monitor fluid intake
muscle weakness, and output
restlessness,  Monitor urinalysis
urinary and kidney function
incontinence, test for
clonic abnormalities
movements,  Instruct patient to
stupor, azotemia, take the medication
leukocytosis, with food or milk
nephrotoxicity  Maintain normal
dietary intake of
sodium with
adequate
maintenance of
 fluid ( 10 to 12 8 oz
glasses of water
daily ) to avoid
lithium toxicity
since lithium
enhance sodium
depletion.

GENERIC/ ACTIONS INDICATION DOSAGE CONTRAINDICATIONS ADVERSE EFFECT NURSING

BRAND INTERVENTION
Nozinan Nozinan For the treatment 50mg OD There are no absolute  Sleepiness.  Assess neurologic
(analgesic) exerts its of psychosis, (night) contraindications to the  Weakness or loss of and psychiatric
actions particular those of use of Nozinan in strength (asthenia). status
through a schizophrenia, and terminal care.  Dry mouth.  Administer
central manic phases of  A drop in blood medication with
adrenergic- bipolar disorder. pressure that occurs food or milk
blocking, a when going from lying  Increase oral fluid
dopamine- down to sitting or intake and
blocking, a standing, which results encourage the
serotonin- in dizziness and inclusion of
blocking, and lightheadedness sufficient roughage,
a (postural hypotension). fresh fruits,
anticholinergic  Constipation. vegetables and
blocking.  Skin rashes. whole grain
 Interference with the products in the diet
body's temperature  provide for patients
regulation (this is more safety during
common in elderly episodes of
people and may cause dizziness
heat stroke in very hot  monitor blood
weather or hypothermia serum level
in very cold weather).  monitor bp daily in
 Decrease in number of both supine and
blood cells in the blood standing position
(agranulocytosis) and teach the client
 Abnormal heart beats to rise slowly from
(arrhythmias). supine to sitting
position; encourage
patient to sit or lie
down if feeling
“faint”.
 Provide chewing
gum or ice chips for
the client to suck to
relieve dryness of
mucosa.