JNC-8 Hypertension Treatment Choices f 1 f L Age 260 years ‘Age <60 yes alloges tages. Diabetes present AD present wth NockD orwithout betes i z Sion pressure goat Blood presure goat ‘ion pressure goat ‘lod pressure goat saP<150mmbg 8° <140.mm My saP<140mn¥g BP <140 mm Ho «90 nn Hg ‘DBP <90.mm Hy DaP <30mm Hg DBP <0 mim T Nonblack lack \" races Initiate thiazide-type diuretic Initiate thiazide-type diuretic Initiate ACEI or ARB, alone ‘0r ACEI oF ARB or CCB, alone or CB, alone ‘rin comoination with other ‘or incombination.* rin combination. rugelass* I I I Selecta dag rextmertittionsateay Aine fst medication bef dng second ot 8. Addsecend meiation before reachin maxenum des of fist medication € Stat wit 2meckation clases separately oa aos combination James et al JAMA December 13 2014ADCORIMEREN |ANGANAN HIPERTENSI BERDASARKAN INC Hipertensi Suge 1 ‘YDS>140-159 mmHg. TDD > 90-99 mmis Diurotik Jonis Tiazide ‘untuk semua pasien. Bisa dipertimbangkan dari kelas lain ACEI. ARB, BB, dan CCB. Kepanjangan Obat: ACE) Hipertensi Stage 2 1DS=160 mmtig TDD> 100 mmiig. Sengam ‘Faltor Restice (itt abel) ‘Duta obat kombinast ‘untuk semua pasien (biasanya Diuretik jenis Tiazid dan ACEI atau AR aiatt BE sta CCB), : TDDsfiekanan Darah Diastolik 1. angi ‘converting enzim: ARB, angiotensin reseptorbloker: BB. beta bloker; calsium chanel bloker.ications for individual drug classes AB B | comactun tt [ACC/AMA Heart Failure Guideline 'MERIT-HE* COPERNICUS,” C1 Hear fature elf} | edll| bs + | SowpesAIRE® TRACE. ValHErT= RALES* [ACCARA Posen Gudeune BEAT?” Postmyocardial infarction alls +_ | SAVE: Copricam,» EPHESUS" ee | ALLHAT,® HOPE,” ANBP2,* LIFE,” Highcomnayydcescerise |. |. | “ convince" NKFADA Guideline," UKPDS," Diabetes al[ | a [s || mica ‘euaiie) NFK Guideline Captopril Trial,® Recurert stoke preventon |. A + Compaling indications fer antihypertensive drugs ae based on benefits fom outcome studies or existing ical idetnes; the compelling indications managed in parle withthe BP. + Drug abbreviations ACE angictensie converting enzyme Inhibitor, ARB, angiotensin receptor blocer; [ido ANT, aldosterone antagonist; BE, beta blocker, CCB, ccm channel blocker. + Conditions fr which clincal tris damonstiate benefit of spec classes of antiypertonsive drugs. POSSIBLE COMBINATIONS OF CLASSES OF ANTIHYPERTENSIVE DRUGS ‘Thiazide+ BB: increased rnew-onset OM ACE = again comer ray Only DHP-CcB should ‘normally be combined ‘with beta-blockers Green dashed line: useful combination (with some limitations}; Black dashed lines: possible but less well-testecl combinations: Green continuouslines: prefered combinations; | Red confinuousline: not recommended combination.