VIVA QUESTIONS FOR PHARMACOLOGY I

UNIT I

1. List out various sources of crude drugs?

2. Writ different routes of drug administration?
3. Describe about phase III and Phase IV clinical trials?
4. Define agonist, antagonist, partial agonist and inverse agonist?
5. Differentiate synergistic effect and commutative effect?
6. Mention the factors effecting drug absorption?
7. Define therapeutic window, pharmacovigilance & pharmacogenomics?
8. Mention factors modifying drug action?
9. Write general mechanisms of drug action?
10. List out metabolic enzyme inducers and inhibitors?
11. Mention different types of receptors with examples?
12. Describe about GPCR?
13. List out various receptors of sympathetic and parasympathetic neurons?
UNIT II
14. Write various enzymes for metabolizing each type of neurochemical transmitter of ANS?
15. Classify sympathomimetic and sympatholytics?
16. What is myasthenia gravis and how it will be treated?
17. How an organophosphorous compound poisoning is to be treated?
18. Describe about muscles involved in pupil size adjustment and the role of sympathetic
and parasympathetic neurons on pupil size accommodation?
19. Write the effects of adrenaline, noradrenaline and isoprenaline on systolic and diastolic
BP and on heart rate?
20. Define glaucoma? Write the mechanism to treat it using drugs acting on ANS?
21. Write adverse effects and uses of α blockers?
22. Write adverse effects and uses of β blockers?
23. Classify NMJ blockers?
24. Classify ganglionic stimulants and ganglionic blockers?
25. Write about α agonists used ad nasal decongestants?
26. Write the mode of action of lidocaine?
27. List out adverse effects of atropine and scopolamine?
28. Explain Henry Dale’s vasomotor reversal phenomenon?
29. List out different pharmacological uses of each anticholonesterases?
30. Write about effect of sympathetic system on metabolic activities?
31. Enumerate the drugs used in the treatment of migraine?
32. Explain different routes of application of local anesthetics?
 UNIT III
33. Mention different central neurochemical transmitters?
34. What is preanaesthetic medication and write its importance with examples?
35. Classify general anesthetics?
36. Explain about different stages of anesthesia?
37. Enumerate different adverse effects of halothane?
38. Explain about different stages of sleep cycle?
39. Classify sedatives and hypnotics?
40. Differentiate the role of barbiturates and benzodiazepines as sedatives and hypnotics?
41. Mention the adverse effects of barbiturates with each specific drug?
42. Write about centrally acting muscle relaxants?
43. Write the mechanism of action of pheniobarbitone and carbamazepine?
44. Describe the therapeutic uses and adverse effects of diazepam?
45. Explain about MAO inhibitors?
46. Write the therapeutic uses and adverse actions of amphetamine?
47. What is the role of disulfiram in the treatment of alcohol dependence?
48. Define drug abuse, drug addiction and drug dependence?
49. Describe about different types of drug tolerance?
UNIT IV

50. Define mania? Name the drugs used to treat it?

51. Write the mechanism and adverse effects of imipramine?
52. Define neuroleptics and classify them with examples?
53. Classify SSRI and write their uses and adverse effects?
54. Define schizophrenia? List out drugs to treat it?
55. Classify atypical antipsychotics and write their uses?
56. Explain about extrapyramidal side effects caused by antipsychotics?
57. Define parkinson’s disease and classify antiparkinson’s drugs?
58. Write different mode of actions of antiparkinson’s drugs?
59. Define Alzheimer’s disease and classify drugs used to treat it?
60. Mode of action and uses of sodium valproate?
61. Define epilepsy and classify them? Write DOC of each type of epilepsy?
62. Rationale of using carbidopa and levo dopa?
UNIT V

63. Describe role of arachidonic acid in prostaglandin synthesis?

64. List out propionic acid derivatives uses as analgesics and write their adverse effects?
65. Adverse effects of non selective COX inhibitors?
66. Adverse effects and uses of paracetamol and aspirin?
67. Classify narcotic analgesics?
68. Morphine uses and adverse effects?
69. Describe about narcotic antagonists?
70. Name the antidotes for morphine poisoning and paracetamol poisoning?