Notre Dame University

College of Health Sciences

Cotabato City

1st Semester
SY 2018-2019

DELIVERY ROOM
Cotabato Regional and Medical Center (CRMC)

Intramuscular and Intravenous Opioid Pain Relieving Drugs in Labour

Submitted by:
Kanakan, Farhana K.
Group A2
Submitted to:
Prof. Jeory B. Gutigulao, RN
Date of Submission:
August 8, 2018
 Intramuscular and Intravenous Opioid Pain Relieving Drugs in Labour
Objective Problem Intervention Comparison Outcome References
A. To assess the We set out to We included randomised We included 70 studies that compared an Though most evidence is Smith LA, Burns E,
effectiveness, determine the controlled trials examining opioid with placebo or no treatment, of low- or very-low Cuthbert A (2018,
safety and effectiveness, side the use of intramuscular or another opioid administered quality, for healthy June 5). Parenteral
acceptability to effects and intravenous opioids intramuscularly or intravenously or women with an opioids for
women of acceptability to (including compared with TENS applied to the uncomplicated pregnancy maternal pain
different types, women of different patient-controlled analgesia) back. Sixty-one studies involving more who are giving birth at management in
doses and modes opioids (pain killers), for women in labour. than 8000 women contributed data to the 37 to 42 weeks, labour. Cochrane
the doses used and review and these studies reported on 34 parenteral opioids appear
of administration Database of
how they are given Cluster-randomised trials different comparisons; for many to provide some relief
of parenteral Systemic Reviews
during labour. We were also eligible for comparisons and outcomes only one from pain in labour but
opioid analgesia were also concerned inclusion, although none study contributed data. All of the studies are associated with 2018, Issue 6. Art.
in labour. about the effects of the were identified. We did not were conducted in hospital settings, on drowsiness, nausea, and No.: CD007396.
B. To assess the opioids on the baby in include quasi-randomised healthy women with uncomplicated vomiting in the woman. DOI:
effects of opioids terms of its safety, trials. We looked pregnancies at 37 to 42 weeks' gestation. Effects on the newborn 10.1002/14651858.
in labour on the alertness at birth and at studies comparing an We excluded studies focusing on women are unclear. Maternal CD007396.pub3
baby in terms of early feeding. opioid with another opioid, with preeclampsia satisfaction with opioid
safety, condition placebo, no treatment, other or pre-existing conditions or with a analgesia was largely
at birth and early Uterine contractions nonpharmacological compromised fetus unreported.
feeding. cause pain during interventions (transcutaneous
labour, particularly as electrical nerve stimulation
they reach their peak. (TENS)) or inhaled
analgesia.