Clerks’ Mock Chart

ASMPH Year Level 8 Internal Medicine Rotation

Name: PIN:
Birth Date: Age:
Sex: Visit Type:
Physician: Room No.:

DRUG DA T A BA SE
Generic Name: Brand Name/s:
Potassium Citrate Kairate, Noston, Tascit, Urecit , Urocit-K
Drug Class: Dosage Forms:
Urine Alkalinizing Agents 10 mEq(1080 mg) K Citrate
15 mEq(1620 mg) K Citrate
Drug Structure: Drug Appearance:

 10 mEq tablets are uncoated, tan to

Potassium citrate is a potassium salt of citric acid
with the molecular formula K₃C₆H₅O₇. It is a white,
hygroscopic crystalline powder. It is odorless with
a saline taste. It contains 38.28% potassium by
mass. In the monohydrate form it is highly
hygroscopic and deliquescent.
yellowish in color, elliptical shaped, with
610 debossed on one side and MISSION on
the other
 15 mEq tablets are uncoated, tan to
yellowish in color, modified rectangle
shaped, with M15 debossed on one side and
blank on the other

Indications:

Renal Tubular Acidosis with calcium stones

Hypocitrauric Calcium oxalate nephrolithiasis of any etiology
Uric acid lithiasis with or without calcium stones
For correcting renal tubular acidosis disorders

Dosing: Cost:
10 mEq- 495/ box of 30s
Urinary citrate of >150 mg/day: 30 mEq/day TID or 15 mEq- 2025/ box of 100s
BID
Urinary citrate <150 mg/day: 60 mEq/day PO TID
or BID
Should be taken 30 mins after meals. Do not
crush/chew
Maintenance: Titrate dose to achieve urinary
citrate >320 mg/day and urinary pH of 6 -7
Contraindicated in patient s with renal
insufficiency (eGFR <0.7 ml.kg.min) or chronic
renal failure
 Clerks’ Mock Chart
ASMPH Year Level 8 Internal Medicine Rotation
Adverse Effects:
Serious Reactions
Hyperkalemia
GI Bleeding
Intestinal stenosis/lesions
Metabolic Alkalosis

Common Reactions
Abdominal pain
Vomiting
Diarrhea
Nausea

Drug Interactions:
Contraindicated with concomitant K+ sparing diuretics: triamterene, spironolactone, amiloride)
Serious interactions with drospirenone, K acid phosphat
Aliskiren- enhanced hyperkalemic effects
Alpha/Beta Agonist - may increase serum concentration
Aluminum Hydroxide- increased concentration
Amphetamines- decreased excretion
ARB- enhance hyperkalemic effect
Quinine- increased serum concentration
Nicorandil- increased hyperkalemic effect
Memantine- increased serum concentration
Eplerenone- contraindicated
Anticholinergic agents- enhance ulcerogenic effect of potassium citrates

Mechanism of Action: Half-Life:

Alkalinizes urine by binding of citrate to urinary unknown
calcium

Metabolism/Excretion: Onset of Action: 1 hour

Duration: 12 hours
Metabolism: CYP450
Excretion: urine
Bioavailability: Metabolites:
Not available Active Bicarbonate
PA T I E NT CO RRE LA T IO N
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Completed by: ________________________________ Checked by: ___________________________________