REU - 1 REU - 6

Which symptom is NOT typical to lower Which symptom is NOT characteristic

leg nerve root compression? of Felty syndrome?

A) Positive Lasegue-sign A) Inflammatory arthritis

B) Tenderness at the Valleix points High titer rheumatoid factor
B)
C) Positive femoral sign positivity
D) Loss of the Achilles tendon reflex C) Splenomegaly
E) Patellar ballottement D) Pneumoconiosis
E) Granulocytopenia
REU - 2
Which of the following diseases is REU - 7
associated with bone erosion? It does NOT belong to the
characteristics of adult-onset Still’s
A) Osteoarthritis disease:
B) Polymyositis
A) Pigmented villonodular synovitis
C) Osteoporosis
B) High fever
D) Psoriatic arthritis
Maculopapular rash on the upper
E) Multiple sclerosis C)
arms
REU - 3 D) Arthralgia
What medicine is NOT used to treat E) Visceral symptoms
rheumatoid arthritis?
REU - 8
A) Methotrexate It does NOT belong to the diagnostic
B) Leflunomide criteria for systemic lupus
erythematosus:
C) Methylprednisolone
D) Diclofenac A) Anti-DNA positivity
E) Colchicine B) Nervous system manifestation
C) Erosive arthritis
REU - 4
Which of the following is an D) Renal involvement
interleukin-6 R-inhibitor biological E) Butterfly (malar) rash
drug?
REU - 9
A) Etanercept Which is the most common
B) Adalimumab autoimmune disease among the
following?
C) Tocilizumab
D) Infliximab A) Systemic lupus erythematosus
E) Rituximab B) Rheumatoid arthritis
REU - 5
C) Systemic sclerosis
Which clinical symptom is NOT
characteristic of rheumatoid arthritis? D) Sjögren syndrome
E) Dermatomyositis
A) Early morning stiffness in the hands
Symmetrical small joint
B)
inflammation of the hands
C) Small joint erosions on X-ray
D) Anti-CCP positivity
E) Early low back pain with sacroiliitis
REU - 10
Which advanced disease state could be REU - 15
characterized by subcutaneous What side effect is NOT characteristic
rheumatoid nodules? of the antirheumatic biological
treatment?
A) Polymyalgia rheumatica
B) Systemic lupus erythematosus A) Bone marrow depression
C) Rheumatoid arthritis B) Elevated liver enzymes
D) Ankylosing spondylitis C) Growing joint complaints
E) Systemic sclerosis D) Allergic skin reaction
E) Latent tuberculosis flare-up
REU - 11
Which of the listed diseases is more REU - 16
common in men? Symptoms of sarcoidosis, EXCEPT:

A) Ankylosing spondylitis A) Granulomatous systemic process

B) Rheumatoid arthritis B) Bilateral hilaris lymphadenopathy
C) Systemic lupus erythematosus C) Erythema nodosum
D) Polymyalgia rheumatica D) Arthritis
E) Sjögren syndrome E) Polychondritis

REU - 12 REU - 17
What is the base (first-line) therapy for What subgroup of juvenile idiopathic
rheumatoid arthritis? arthritis is characterized primarily by
rheumatoid factor positivity?
A) Sulfasalazine
B) Cyclophosphamide A) Polyarthritis
C) Methotrexate B) Systemic form
D) Chloroquine C) Oligoarthritis
E) Azathioprine D) Enthesopathic arthritis
REU - 13 E) Psoriatic arthritis
What is the most important
immunological marker of mixed REU - 18
connective tissue disease (MCTD)? NOT a symptom of Scheuermann's
disease:
A) Anti-CCP
B) Antinuclear factor A) Dorsal hyperkyphosis
C) Anti-SSA Forwardly wedge-shaped vertebrae
B)
formation
D) Anti-U1RNP
C) Uneven vertebrae closing plates
E) Anti-SSB
D) Moderate back pain of teenagers
REU - 14
What joints are NOT affected in Association of avascular necrosis of
E)
rheumatoid arthritis? femoral head

A) Metacarpophalangeal (MCP) joints

Proximal interphalangeal (PIP)
B)
joints
C) Distal interphalangeal (DIP) joints
D) Knee joints
E) Radiocarpal joints
REU - 19 REU - 23
It does NOT belong to seronegative Which pathogen causes Lyme disease?
spondyloarthritis:
A) Campylobacter jejuni
A) Ankylosing spondylitis B) Klebsiella pneumoniae
B) Reactive arthritis C) Borrelia burgdorferi
C) Enteropathic arthritis D) Coxsackie virus
D) Polymyalgia rheumatica E) Epstein-Barr virus
E) Psoriatic arthritis
REU - 24
REU - 20 What symptom group is NOT
NOT characteristic of ankylosing characteristic of Lyme disease?
spondylitis:
A) Erythema migrans
Elevated erythrocyte sedimentation B) Arthralgia - Arthritis
A)
rate
C) Neurological lesions
Low back pain worsens after
B) D) Cardiac changes
activity, improves after rest
E) Severe gastrointestinal symptoms
Low back pain worsens during early
C)
morning rest, improves with activity
REU - 25
D) Early bilateral sacroiliitis Which medicine is NOT effective for
E) Syndesmophytes on spinal X-ray treating an acute gout attack?

REU - 21 A) Allopurinol
NOT a typical symptom of psoriatic
B) Corticosteroid
arthritis:
C) Colchicine
A) Symmetrical arthritis Non-steroidal anti-inflammatory
D)
drugs
Distal interphalangeal joint
B) E) TNF-α inhibiting biological agents
involvement
C) Hyperuricemia
REU - 26
D) Rheumatoid factor negativity
What is the absolute classification
E) Pulmonary fibrosis criteria for gout diagnosis?

REU - 22 Detection of synovial monosodium

Characteristics of joint processes A)
monohydrate crystals
associated with inflammatory bowel
B) Uric acid nephrolithiasis
diseases (IBD), EXCEPT
Occurrence of acute flares of gouty
C)
arthritis
Especially lower extremities
A) D) The presence of tophuses
oligoarthritis
B) Spondarthritis of the spine E) Hyperuricemia
C) Effectiveness of infliximab therapy
Effectiveness of sulfasalazine
D)
therapy
Effectiveness of methotrexate
E)
therapy
REU - 27
What is the most important laboratory REU - 32
symptom of primary osteoporosis? Which symptom is NOT characteristic
of knee osteoarthritis?
A) Elevated alkaline phosphatase
Elevated erythrocyte sedimentation A) Starting pain after inactivity
B)
rate B) Pain in loading position
Elevated parathyroid hormone C) Difficulty in climbing stairs
C)
levels D) Osteophytes on X-ray
D) Decreased serum calcium levels E) Full bone ankylosis
E) None of the above
REU - 28 REU - 33
Which bone disease is NOT Typical symptoms of lumbar discus
characterized by elevated serum herniation, EXCEPT
alkaline phosphatase?
A) Antalgic posture
A) Osteoporosis B) Strong lumbar back pain
B) Osteomalacia Motor weakness of the lower
C)
C) Primary hyperparathyroidism extremities
D) Paget's disease of the bones Loss of tendon reflexes on the
D)
E) Secondary hyperparathyroidism lower limbs
REU - 29 E) Acute abdominal complaints
What condition does NOT lead to
increased formation of osteoarthritis? REU - 34
NOT a characteristic hand change of
A) Hip joint dysplasia rheumatoid arthritis:
B) Significant weight gain
A) Erosions of the small joints
C) Varus / valgus deformity
B) Subluxations of the small joints
D) Excessive arthritis
C) "Pencil in cup" lesion
E) HLA B-27 positivity
D) Bone ankylosis
REU - 30
NOT indicated for the treatment of Swan-neck and boutonniere finger
E)
acute osteoporotic vertebral fracture: deformity on the hands
REU - 35
A) Strong analgesia It does NOT play an important role in
the pathogenesis of rheumatoid
B) Administration of ischias infusions
arthritis:
Progressive mobilization of the
C)
patient with spinal physiotherapy
A) Activation of Th1 line
D) Therapeutic X-ray irradiation
B) Activation of the Th17 line
Occasionally vertebroplasty
E) C) Activation of the Th2 line
procedure
REU - 31
D) Decreased operation of Treg cells
In which joints does Heberden’s E) Decreased formation of cathepsins
osteoarthritis develop?

A) In distal interphalangeal joints

B) In proximal interphalangeal joints
C) In knee joints
D) In the small joints of the leg
E) Anywhere
REU - 36 the 2nd, 3rd and 4th answers are
Which illness is associated with C)
correct
increased erythrocyte sedimentation the 3rd, 4th and 5th answers are
rate of the following? D)
correct
1) Osteoporosis the 1st, 2nd and 3rd answers are
E)
correct
2) Psoriatic arthritis
3) Osteoarthritis REU - 39
4) Rheumatoid arthritis Genetic subtypes predominant to
5) Polymyalgia rheumatica rheumatoid arthritis

1) HLA DRB1*01
the 1st, 4th and 5th answers are
A) 2) HLA DRB1*04
correct
3) HLA DRB1*10
the 2nd, 4th and 5th answers are 4) HLA B27
B)
correct 5) HLA B35
the 1st, 3rd and 4th answers are
C)
correct the 1st, 2nd and 4th answers are
A)
the 2nd, 3rd and 4th answers are correct
D)
correct the 1st, 3rd and 5th answers are
B)
the 1st, 2nd and 5th answers are correct
E)
correct the 1st, 2nd and 3rd answers are
REU - 37 C)
correct
Which two immunological findings are the 3rd, 4th and 5th answers are
specific in rheumatoid arthritis? D)
correct
1) Anti-CCP the 2nd, 3rd and 5th answers are
E)
correct
2) Anti-SSA
3) Anti-U1RNP REU - 40
4) Rheumatoid factor Clinical features of polymyalgia
5) Antinuclear antibody rheumatica

1) Occurrence in older women

A) the 1st and 4th answers are correct
2) Symmetrical shoulder- and hip
B) the 1st and 5thanswers are correct muscle pain
C) the 4th and 5th answers are correct 3) High level of erythrocytes
D) the 3rd and 4th answers are correct sedimentation rate
E) the 1st and 2nd answers are correct 4) It primarily occurs in men
5) Unilateral shoulder- and hip
REU - 38 muscle pain
What are the contraindications of
antirheumatic biological therapy? the 2nd, 3rd and 4th answers are
A)
correct
1) Strong joint arthritis the 1st, 2nd and 3rd answers are
B)
2) Active tuberculosis correct
3) NYHA class 3-4 heart failure the 1st, 3rd and 5th answers are
4) The existence of malignant C)
correct
disease the 2nd, 3rd and 5th answers are
5) Rheumatoid factor positivity D)
correct
the 3rd, 4th and 5th answers are
the 1st, 3rd and 4th answers are E)
A) correct
correct

the 2nd, 3rd and 5th answers are
B)
correct
REU - 41
Characteristics of juvenile idiopathic the 1st, 2nd and 4th answers are
arthritis A)
correct
the 1st, 2nd and 3rd answers are
1) Begins before the age of 16 B)
correct
2) Growth restriction of the child
the 1st, 2nd and 5th answers are
3) Reduced mental development of C)
correct
the child
4) Joint pain is generally mild the 1st, 4th and 5th answers are
D)
5) Biological therapy not applicable correct
the 1st, 3rd and 4th answers are
E)
the 1st, 2.nd and 4th answers are correct
A)
correct
the 1st, 3rd and 4th answers are REU - 44
B) Which drugs are used to treat
correct
osteoporosis from the following?
the 1st, 4th and 5th answers are
C)
correct
1) Bisphosphonates
the 1st, 2nd and 3rd answers are 2) Teriparatide
D)
correct 3) Hyaluronic acid
the 1st, 3rd and 5th answers are 4) Denosumab against RANKL
E)
correct 5) Chondroitin sulphate

REU - 42 the 1st, 2nd and 4th answers are

Clinical changes in ankylosing A)
correct
spondylitis the 1st, 3rd and 5th answers are
B)
correct
1) Ankylosing inflammation of the
the 1st., 2nd and 5th answers are
spine C)
correct
2) Association of acute anterior
uveitis the 1st, 3rd and 4th answers are
D)
3) More frequent association of correct
lymphomas the 2nd, 4th and 5th answers are
E)
4) Peripheral enthesitis correct
5) Sicca syndrome
REU - 45
the 1st, 2nd and 5th answers are In case of infectious arthritis, what are
A) the first things to do?
correct
the 1st, 2nd and 4th answers are
B) 1) Put the joint in resting position
correct
2) Administration of broad-spectrum
the 1st, 2nd and 3rd answers are antibiotics
C)
correct
3) X-ray examination
the 1st, 3rd and 4th answers are 4) Aspiration of joint fluid
D)
correct 5) Isotope scan
the 1st, 4th and 5th answers are
E)
correct A) the 1st and 2nd answers are correct
B) the 1st and 3rd answers are correct
REU - 43
the 2nd and 3rd answers are
Typical triage of Reiter's disease C)
correct
1) Arthritis after enteral infection D) the 3rd and 4th answers are correct
2) Urethritis E) the 1st and 5th answers are correct
3) Conjunctivitis
4) Pneumonitis
5) Ulcerous colitis