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The 6th International Conference of the Indonesian Chemical Society 2017
Hotel Horison Ultima, Palembang, Indonesia
October 15 - 20, 2017
The 6th Himpunan Kimia Indonesia (HKI) annual conference on Tue-Wed, 17-18
October 2017, is organized by South Sumatera Branch of HKI in collaboration with
Sriwijaya University (Unsri) and South Sumatera Province. South Sumatera was
selected as the location for 2017 HKI annual conference in HKI National Meeting
2014, 3 years ago, in Ambon, Maluku. This is a bilingual conference (Indonesian and
English), which means that the paper can be written in English or Indonesian
language (Bahasa Indonesia), and the presentation can be delivered in English or
Bahasa Indonesia.
Before, parallel to, or after the conference, there will be several satellite activities
(workshop, etc.), including a meeting of the Forum of Head of Chemistry Departments
in Indonesia (Temu Forum Ketua Jurusan/Prodi Kimia dan Pendidikan Kimia se-
Indonesia 2017, Temu FKJKI-2017), contact: fkjki-2017@kimiawan.org) that will be
started in the evening (19.00) of 17 October 2017. Any chemistry-related
communities/institutions could register other satellite activities (one-day workshop,
symposium, training, etc.) to icics-2017-satellite@kimiawan.org, to be offered to
conference attendees. Satellite activities could be held in any date between 3 October
to 31 October 2017.
One day before the conference, on Monday, 16 October 2017, HKI Congress will be
held to find the next President-Elect of HKI. The elected person will be the next
President-Elect of the Indonesian Chemical Society from 1 January 2018 to 31
December 2018, while Dr. Tatas Brotosudarmo will be the President of HKI.
Speach by Chairman
I would like to inform some formal information related to this conference. The
conference’s theme is “Stimulating of Advanced Perspective and Current Concepts on
Chemistry field”. The goals of conference are to provide a vehicle the state of the art
in research results and trends in chemistry field, to offer interaction, discussion and
possible collaboration among chemist and the public about chemistry, to increase
awareness of policy makers and public on chemistry’s rule in national development.
This conference consists of 4 keynotes speakers from USA, Japan, Solomon Island, 8
invited speakers, and 229 participants who deliver as oral or poster presenters.
Accompanying this conference, there are some activities: Indonesia high level
meeting on chemical security by Sandia USA (15-16 October), Congress of PNHKI (16-
17 October), FKJKI meeting (18 October), and Palembang city tour (19 October).
I would like also to express thanks and appreciation to the organizing committee for
their cooperative work and efforts to make our conference a success.
Finally, I would like to thank to all participants and their respective institutions that
have made this conference possible and I wish you all have a pleasant meeting.
I sincerely wish you would have most productive days of interesting and stimulating
discussions. I believe that this conference is a great opportunity not only for sharing
knowledge and experience in chemical research, but also for starting a long and
fruitful cooperation and friendship among Academicians, Researchers and
practitioners of Chemistry.
Finally, I would like to thank and congratulate the organizing committee for their
dedication and tremendous efforts in organizing the conference. I wish you all an
enjoyable meeting and fruitful discussion.
Bismillahirrohmaanirrohim
Assalamualaikum warohmatullahi wabarakatuh,
In the name of Alllah SWT and all praise belongs to Him who is blessing us today to
come and attend this important conference.
By this conference also I hope that it facilitates Indonesian chemists to publish their
research results in reputable journal/proceeding.
I am sincerely grateful to welcome honorable keynote speakers, distinguished invited
speakers and excellent of participants for sharing their knowledge in this conference.
This conference will be able to meet our goals and objectives and provide a
rewarding experience to all participants, from local and international. My
appreciation also goes to the organizing committee for making this conference a
success.
I take this opportunity to thank and to appreciate the Sandia and CRDF United State
of America which have hold the workshop on ‘Indonesia high level meeting on
chemical security’ on October 15-16, 2017.
“Bismillahirrohmaanirrohim”
Good luck, I wish you all an enjoyable meeting and fruitful discussion.
PLENARY SESSION
10.00 – 10.40 1. Andrew Nelson, Ph.D, MPH – Sandia Lab., USA
Moderator : Prof. Mudasir, Ph.D.
10.00 – 11.20 2. Muhamad Abdulkadir Martoprawiro, Ph.D – ITB, Indonesia
Moderator: Prof. Dr. Subandi, M.Si
PLENARY SESSION
08.00 – 08.40 1. Prof. Dr. Basil Shelton Marasinghe
Moderator: Prof. Wega Trisunaryanti, MS, Ph.D. Eng.
08.40 – 09.20 2. Prof. Hisao Yoshida, Kyoto University, Japan
Moderator: Dr. Jarnuzi Gunlazuardi
Room : Semeru 1
Moderator : Risfidian Mohadi
Reg.
Time Name Title
Number
13.00 - 13.15 IS 1 Didin Mujahidin (Invited The Utilization of Palm Oil as Renewable Block
Speaker) Building Source in Chemical Industry
13.15 - 13.30 IS 2 Muktiningsih Nurjayadi Immunogenicity Evaluation of Recombinant Fim-C
S. Typhi Protein as Typhoid Vaccine Candidate on
Wistar Rat to Increase the Quality of Urban Health
in Indonesia
14.45-15.00 OP 6 Ani setyopratiwi The Effect Of Addition Black Cimun Seed Oil Extra
Virgin Coconut Oil On The Physical And Chemical
Properties
16.45 - selesai OP 13 Nunuk Hariani Soekamto Dengue Antivirus Activity of Non Polar Extract From
Melochia Umbellata (Houtt) Stapf Var. Visenia
Room : Semeru 2
Moderator : Henny Yohandini
Reg.
Time Name Title
Number
13.00 - 13.15 IS 3 Sal Prima Biomolecules-Mediated Synthesis of Gold and Silver
Nanoparticles: Recent Developments
14.30 – 14.45 OP 19 La Ode Agus Salim Pumice stone coated with Mn-N TiO2 as
photocatalyst for linear Alkylbenzenesulfonate
degradation under visible light
14.45 – 15.00 OP 20 Tanto Budi Susilo Characterization, Dating 14C and Compotion of
Banjar’s boat Artifact From Around Candi Laras site,
Barito River-Kalimantan
15.00 COFFEE BREAK
15.15 – 15.30 OP 21 Pra Dian Mariadi Lead and Cadmium Mobilization from Anas moscha
and Cairina Moschata Tissue using Pineapple
extract as chelating agents
16.15 – 16.30 OP 25 Lia Cundari Batch Study, Kinetic and Equilibrium Isotherms
Studies of Dye Adsorption of Jumputan Wastewater
Onto Betel Nuts Adsorbent
Room : Semeru 3
Moderator : Muhammad Said
Reg.
Time Name Title
Number
13.00 - 13.15 IS 4 Suyanta Electrocoagulation tebhnic for imporovement
quality of swimming pool water
13.15 - 13.30 OP 28 R. Arizal firmansyah Science Process Skills and Mastery of The Concept
(Ketua Jurusan) Acid Bases and Buffers Through POGIL (Process
Oriented Guided Inquiry Learning)
13.30 – 13.45 OP 29 Kasmudin Mustapa The Effect of Cooperative Learning Model Scramble
And Talking Stick to The College Students
Motivation and Learning Outcomes in Basic
Chemistry Subject on Chemistry Education Tadulako
University
13.45 – 14.00 OP 30 Lela mukmilah yuningsih The Effect of Activation Of Active Carbon from Corn
(Ketua Jurusan) Cobs and Coconout Shells on The Value of
Conductivity
15.15 – 15.30 OP 34 Retno Dwi Suyanti The Implementation of Project Based Learning
Model on Buffer solution
Room : Leuser 1
Moderator : Bambang Yudono
Reg.
Time Name Title
Number
13.00 - 13.15 IS 6 Subandi Antibacterial and Xanthin Oxidase Inhibition Power
of Peanut (Arachis hypogaea l.) Peel Ethanol Extract
13.15 - 13.30 OP 43 Hendrawan Poly (Vinyl Alcohol)/Glutaraldehyde/Premna
Oblongifolia Merr Extract Hydrogel for Controlled-
Release and Water Absorption
13.30 – 13.45 OP 44 Suharti Crude Extract of Keratinase from A Newly Isolated
Pseudomonas Sp Exhibits Dehairing Activity of Goat
Skin.
13.45 – 14.00 OP 45 Elok Kamilah Hayati Antimlaria Assay Activity And Identification of
(Ketua Jurusan) Marker Compound Extract Of Anting-Anting Herb
(Acalypha Indica L.
15.30 – 15.45 OP 51 Pratiwi Pujiastuti Low Cost Production of Hard Shell Capsules from
Seaweed-Starch
16.00 – 16.15 OP 53 Nanik Dwi Nurhayati Preparation And Effect of Adipic Acid on Local
Shellac Modification Based On Material Packaging
16.30 – 16.45 OP 55 Chairil Anwar Synergy Effect of Ferulic Acid and Curcumin Analogs
Towards Α –Glucosidase
16.45 – 17.00 OP 56 Dedy Suhendra Extraction and Preconcentration Of Zinc(II) Ion By
Fatty Hydroxamic Acids Immobilized onto Zeolit
Room : Dempo
Moderator : Eliza
Reg.
Time Name Title
Number
13.00 - 13.15 IS 7 Jarnuzi Gunlazuardi Artificial Photosynthesis for Water Splitting: New
Device Type Based on Modified Dyes Sensitized
Solar Cell Having Catalysis Zone Extension.
13.45 – 14.00 OP 60 Siti Mariyah Ulfa The Comparison Activity of Ni/Al2O3-Zro2 and
Cu/Al2O3-Zro2 on The Hydrogenation Of Phenol in
Water Solvent
14.15 – 14.30 OP 62 Endang Tri Wahyuni Collectable Silica Based Adsorbent From Volcanic
Ash
14.30 – 14.45 OP 63 Sri Wardhani Effect of pH Phenol on The Ability of Thin Layer
Photocatalyst TiO2- Chitosan To Degrade Phenol
with UV Light
14.45 - 15.00 OP 64 Jaya Putra Utama Electrostatic Method For Separation of Glycerin
and Biodiesel
Room : Kerinci
Moderator : Poedji L.H
Reg.
Time Name Title
Number
13.00 - 13.15 IS 8 Aldes Lesbani Supramolecular Ionic Crystals Based on
Polyoxometalates-Organometallic Complexes
13.30 – 13.45 OP 74 Paramita Jaya Ratri Structural study of the ordering processes of cold
drawn trans-1,4-polyisoprene samples in the
heating process on the basis of wide- and small-
angle X-ray scattering measurements
14.00 – 14.15 OP 76 Purkan Fikih Properties of mercury reductase enzyme from local
Bacillus sp. for bioremediat ion agent
15.15 – 15.30 OP 80 Lukman Hakim Anomalous negative thermal expansion of ice from
Gruneisen parameter
15.30 – 15.45 OP 81 Yuni Krisyuningsih Synthesis and characterization of zeolite NaY from
Krisnandi kaolin Bangka Belitung with variation of synthesis
composition and crystallization time
16.00 – 16.15 OP 83 Dasril Basir Free Solvent Amidation of Ursolic and Oleanolic
Acids of Fragraean Fragrans Fruits; Their P-388
Antitumor Activity
16.15 – 16.30 OP 84 Yuni Krisyuningsih Cellulose conversion of delignified rice husk waste
Krisnandi to levulinic acid using hierarchical Mn 3O4/ZSM-5,
Mn3O4, and Mn2+ Catalysts
Room : Semeru 1
Moderator : Nirwan Syarif
Reg.
Time Name Title
Number
10.30 – 10.45 OP 90 Rachmat T. Tjahjanto The Synthesis of graphene from natural graphite
using moditified Hummer method
11.30 – 11.45 OP 94 Masdania Zurairah Characterisation Carbon Nanotube from Rice Husk
Siregar Activated Carbon as Adsorbent to Reduce Peat
Water
13.00 – 13.15 OP 96 Manihar Stumorang Antimalarial activity of extract and fraction of Temu
mangga (Curcuma mangga) rhizomes
13.30 – 13.45 OP 98 Septianty Magdalena Study adsorption ion Lanthanum and Erbium using
Simanjuntak pectin from banana peel
14.00 – 14.15 OP 100 Evi Maryani The Anti-Fungal Effect of Candida Albican Cause
“Candidiasis” in Various of liquid substances with
ZnO Nanoparticles and TiO2 Combination as Active
Ingredients
14.15 – 14.30 OP 101 Lalu Rudyat Telly eicosenoic Acids Derivatives as Novel Inhibitors for
Savalas Mycobacterium Tuberculosis Protein Tyrosine
Phosphatase B
14.30 – 14.45 OP 102 Tia Okseini Total Phenolic content, Total Flavonoid content and
Antioxidant Activity of the root, Stem Bark and
Leaves Elaeocarpus mastersii King.
Room : Semeru 2
Moderator : Eliza
Reg.
Time Name Title
Number
10.30 – 10.45 OP 106 Dilia Puspa Fatty Acids from Microalgae Botryococcus Braunii
for Raw Material of Biodiesel
10.45 – 11.00 OP 107 Sri Mulyani In vitro Analysis of PcpB Protein Function in
Pentachloropseudilin biosynthesis from
Actinoplanes Sp.
11.00 – 11.15 OP 108 Sofijan Hadi Increasing the production of the extracellular
thermophilic β-xylosidase by recombinan Bacillus
megaterium MS941
11.45 – 12.00 OP 111 Ronaldo Irzon Rare Earth Elements Identification on Granitoid
from unggan,Sijunjung, West Sumatera
13.30 – 13.45 OP 114 Ghufira Activated Carbon From Palm Oil Waste as
Bioadsorbent on dyes Removal from Aqueoeous
Solution
14.00 – 14.30 OP 116 Irdhawati Irdhawati, Square Wave Anodic Stripping Voltammetry For
Liana Sari, Determination of Lead in Water Spinach From
Badung River Estuary
15.00 – 15.15 OP 119 Suherman Suherman, Colorimetric And Electrochemical Methods For
Kento Yajima, Kinichi Water Quality Test
Morita, Toshikazu
Kawaguchi
15.15 – 15.30 OP 120 Eka Febri Zulissetiana, The Efficacy of Methanol Extract of Morinda
Susilawati Citrofolia to brain Derived Neutrophic Factor
(BDNF) and Spatial Memory Ability on male Swiss
Webster Mice Induced by Immobilization Stress
Room : Semeru 3
Moderator : Ferlinahayati
Reg.
Time Name Title
Number
10.30- 10.45 OP121 Daniel tarigan Synthesis of oleic chitosan as film coating by
interesterification and amidation reactions from
unsaturated fatty acid
10.45 – 11.00 OP 122 Pepi Helza Yanti Preparation of hydroxyapatite using Geloina
coaxans shell in various solvents
11.00 – 11.15 OP 123 Nurhasanah husin Characterization of Lack Signal Peptida Lipase
From Compost Metagenome
11.15 – 11.30 OP 124 Aliya Nur Hasanah Synthesis and characterization of molecular
imprinted polymer for recognition of atenolol in
biological fluids
11.30-11.45 OP 125 Agus Martono Hadi Shell of Land Keong Emas and Kijing as a Mild
Putranto Concrete for Earthquake Resistant
13.15 – 13.30 OP 128 Anna Safitri XANES Spectroscopy for Characterizing Cr(III)-
Binding Low-Molecular-Weight (LMW) Serum
Fractions using 3D Approuch And Chemometric
Analysis
13.45 – 14.00 OP 130 Tjitjk Srie Tjahjandarie Melimoluccanin, A new isoprenylated quinolone
alkaloid from the leaves of Melicope moluccana
T.G. Hartley
14.00 – 14.15 OP 131 Muhammad Arba QSAR, Molecular Docking and Dynamics Studies
of Pyrrolo[2,3-b]pyridine Derivatives as Bruton’s
Tyrosine Kinase Inhibitors
14.15 – 14.30 OP 132 Mochamad Zakki Fahmi Cellulose-based graphene nanostructure for
comprehensive treatment of cancer disease
14.30 - 14.45 OP 133 Martha Aznury Production Biomethane from Palm Oil Mill
Effluent (POME) with Trucated Pyramid Digester
in Fed Batch System
14.45 - 15.00 OP 134 Erly Grizca Boelan Abilities of Co-Cultures of White-Rot Fungus
Ganoderma linghzi and Bacillus subtilis on
Biodegradation of DDT
15.00 – 15.15 OP 135 Bambang Yudono Oil recovery tests by using bio surfactant of
indigenous Pseudomonas peli and Burkholderia
glumae bacteria from South Sumatera at various
temperature conditions
15.15 – 15.30 OP 136 Noviany Sutopo Hadi Isolation and Structure Elucidation of A New
Naturally Isolated Compound from Sesbania
grandiflora
15.30 – 15.45 OP 137 Adri Huda Methylene Blue Removal using Tin oxide based
Photocatalyst
Room : Leuser
Moderator : Addy Rachmat
Reg.
Time Name Title
Number
10.30 – 10.45 OP 138 Susila Arita Rahman High Conversion and Yield of Biodiesel using
Electrolysis Method
10.45 – 11.00 OP 139 Adil Ginting Glyceryl Monoleate Incoporation with Cinnamon
Bark Essential Oil as The Plastizer on Gelatin
Edible Film
11.00 – 11.15 OP 140 Muhammad Arif Synthesis of Sorbitan Oleate from Sorbitol as
Darmawan Iron Adsorbent and Comparative Capacity of
Adsorption on Pectin
11.45 – 12.00 OP 143 Lukman Atmaja Medium Scale Conversion of Fishermsn Shrimp
Waste Industry to Chitosan
13.00 – 13.15 OP 144 Teja Dwi Sutanto The Effect of Cocopeat Grain Size to Mechanic
Properties of Particle Board
13.15 – 13.30 OP 145 Raedhita Arya Kanigoro Synthesis of Sorbitan Fatty Acid Esters as Ligand
for Zn2+ and Pb2+ Metal Ions in Industrial Sludge
from Tegal
14.00 – 14.15 OP 148 Prima Endang Susilowati Effect Of Selected Ragi On The Reduction Of
Antinutrient Levels During Solid Substrate
Fermentation Of Cocoa Pod Husk and
cottonseed
14.15 – 14.30 OP 149 Sri Sumarsih, Sofijan Production and Partial Purification of Lipase of
Hadi Micrococcus sp. Isolated from Palm Oil Mill
Effluent-Contaminated Soil
15.00 – 15.15 OP 152 Nanik dwi nurhayati Fabrication and investigation of chemical
properties shellac
15.15 – 15.30 OP 153 Alfa Akustia W TiO2 – SiO2 Thin Film for self claning coating on
Glass
Room : Dempo
Moderator : Henni Yohandini
Reg.
Time Name Title
Number
10.30 – 10.45 OP 154 Uswatun Hasanah Characterization of Coconut Shell Pyrolysis Tar
as Renewable Fuel
10.45 – 11.00 OP 155 Fitria Rahmawati Internal gas reforming SOFC with a small flow
bioethanol as fuel
11.15 – 11.30 OP 157 Leily nurul komariah Biodiesel Effects on Fuel Filter; assessment of
clogging characteristics
13.30 – 13.45 OP 162 Boni Junita Lupid Extraction Method from Microalgae
Botryococcus Braunii as Raw Material to Make
Biodiesel with Soxhlet Extraction
13.45 – 14.00 OP 163 Yuli Filindity Application of Modified Free Inquiry on Acid,
Base and Salt Concept to Results Studying
Student Class VII SMP Negeri I Banda
14.00 – 14.15 OP 164 Chanel Tri Handoko Silver Deposition on titanium ocide by using
Liquid Impregnation Method
14.30 – 14.45 OP 166 Fuji Lestari Synthesis of Cholesteryl Acrylate Polymer with
UV Curing Method Using Mercury Lights
14.45 – 15.15 OP 167 Risfidian Mohadi Isolation of B- Kitosan From Squid Bone as
Raw Material to Synthesize of hybrid
Photocatalists TiO2-kitosan
P3 Widinda Normalia Student’s Profile About Analysis Questions Cognitive Level Based on Bloom
Arlianty Taxonomy Version Kreathwohl
P4 Argo Khoirul Anas The Effect of Purification Process on Electrical Conductivity of Multiwall-
Carbon-Nanotubes/Natural-Rubber-Latex Nanocomposite
P6 Ade Heri Mulyati Pendugaan Umur Simpan Tepung Biji Durian Lokal (Durio Zibhetinuss l)
dengan Metode Akselerasi Pendekatan Kadar Air Kritis
P8 Beta Wulan Febriana Analysis of Problem Based Learning in Hidrokarbon Compound Material in
Vocational School
P9 Siti Warnasih Utilization of Cempedak Seeds Waste As Alternative Raw Material for Wheat
Flaur To Produce Oyster Mushroom Meatballs
P10 Artina diniaty VAK (Visual, Auditory, Kinesthetic) Learning Model to Improve Life Skills
P12 Tatang Shabur Julianto The Effect of Mole Comparison of Acetone As Co-Solvent to Methanol in
Transesterification Reaction of Waste Cooking Oil
P13 Baharuddin Hamzah Effects of Copper(II) and Cadmium(II) on Mercury(II) Extraction Percentage
Using Liquid Membrane Emulsion of W/O type with Double Surfactant and
Benzoyl Acetone As Cation Carrier
P14 Muliadi Ramli Biosynthesized of Magnesium Oxide (Mgo) Nanoparticles and Its Application
as An Inorganic Antimicrobial
P16 Dhina Fitriastuti Antimalarial Activity Of Extract and Fraction of Temu Mangga (Curcuma
Mangga) Rhizomes
P17 Siti Wafiroh Synthesis of Membrane Photocatalytic from Pineapple (Ananas comosus)
Leaf Fiber Cellulose Diacetate and TiO2 to Degrade Congo Red
P18 Usreg Sri Handajani Development of Carbon Paste Electrode Modified MIP With Methacrylic Acid
as Monomer to Analyze Creatine by Potentiometry
P19 Noor Fitri Sequential Extraction of Yttrium in Lateritic Soil Weathered From Granitic
Rock in Mamasa, West Sulawesi, Indonesia
P20 Emma Zaidar Nasution The Effect of Natural Feed, Factory and Oils nn The Gurami Fish Weight
(Osphronemus gouramy Lac.)
P21 Fahma Riyanti Effect of NaOH Concentration and Temperature On The Synthesis MnFe2O4
by Co-Precipitation Method
P22 Suharti Cloning and Characterization of a Novel Gene Encoded Thioesterase From
Domas Hot Spring
P23 Rumondang Nasution Toxicity Assay of Methanol Extract Leaves Parasite Coffe With Method Brine
Shrimp Lethality
P24 Nyimas Febrika Functionality Analysis of Carbon Nanosheet, Oxidized Carbon Nanosheet and
Sya'baniah Reduced Carbon Nanosheet Oxide by Using Fourier Transform Infra Red (FT-
IR) and Boehm Titration Method
P26 Hermansyah Bioethanol Production from Cassava (Manihot esculenta) Peel Using Yeast
Isolated from Durian (Durio zhibetinus)
P27 Anna Muawanah Physicochemical, Organoleptic and Prebiotic Properties of Yoghurt Added
With Fermented Breadfruit Flour by Laktobacillus Plantarum
P28 Neza R Palapa Adsorption of Cobalt (II) on Layered Double Hydroxides (Mg/Al and Ca/Al) in
Aqueous Medium : Kinetic and Thermodynamic Aspect
P29 Irfan Gustian Preparation and Characterization of Polymer Electrolyte Membrane Based on
Sulfonated Polystyrene
P30 Rizki Triana Sari Study of Phytic Acid Effectivity as Chelating Agent of Unwanted Metal from
Tin Slag 2 Leaching to Increase Purification of Tantalum and Niobium Oxide
P31 Setyo Nurwaini Formulation of Clove Oil Toothpaste (Syzygium aromaticum (L.) Merr. &
Perry.)
P32 Ika Natalia Mauliza How to Improve Quality of the Colouring Silk using Monascus Dyed Derived
from Cassava Peel Flour Fermentation
P33 Widia Purwaningrum Immobilized Chitosan and Its Application on Fe(III) Adsorption in Peat Water
P34 Cut Fatimah Zuhra Characterization of Starch Breadfruit (Artocarpus Altilis) and Chitosan Edible
Film
P35 Dina Asnawati The Effect Concentration of Lignin Extract Inhibitor From Coconut Fiber
Waste to Iron Corrosion Rate
P36 Jannatin 'Ardhuha Characterization and Partial Purification of Lipase from Cocos nucifera
P37 Mashuni Mashuni Characterization of Total Phenolic Content and Components of Chemical
Pallawagau Compounds by GC-MS from Pyrolisis of Coconut Shell
P38 Nur samsiar In Silico Study of Aglycone Curculigoside a and Its Derivatives With Various
Cancer Receptors
P39 Ida musfiroh Synthesis of Sodium Carboxymethyl Cellulose (Na-CMC) from Water
Hyacinth with Mixed Solvent Using Succinic Acid as Crosslinker
P40 Destri Muliastri Nickel Slag Coated by Titanium Dioxide for Degradation of Methylene Blue in
Water Environment
P41 Muhammad Said Artificial Neural Network (ANN) for Optimization of Palm Oil Mill Effluent
(POME) Treatment using Reverse Osmosis Membrane
P42 Mudasir Linear QSPR Model for Prediction of HPLC Retention Times of Polyaromatic
Hydrocarbons
P43 Parsaoran Siahaan Probing of Interaction Mode Between Cyclic Peptide ADTC3 (Ac-CAD TPC-
NH2) with E-Cadherin Protein using the Molecular Docking Method
P44 Idin Sahidin Secondary Metabolites from Indonesian’s Sponges Xestospongia sp.:
Chemotaxonomy Significance and Antibacterial Properties
P46 Muhdarina Sulphuric Acid Activated Clay (SAACC) as Catalyst for Esterification of Crude
Palm Oil (CPO) to Biodiesel
P47 Anam Khairul Determination of FTIR Spectrum Profile For Quality Assurance of Avicennia
Marina Exudate Extract as Antihyperurisemic Herbal Medicine
P48 Dwiarso Rubiyanto Fruit Fly Attractancy Activity of Ruku-Ruku (Ocimum Sanctum, L.) and Selasih
Ungu (Ocimum Canum, Sims.) Essential Oil Formulated With Virgin Coconut
Oil (VCO)
P51 Eva Marliana The Antioxidant and Antiplasmodial Activities of Methanol Extract From
Macaranga Beccariana Merr. Leaves
P52 Winni Astuti Screening and Characterization of Raw Starch Degradation Amylase from
Bacteria Dondang Hot Spring Kutai Kartanegara
P53 Desnelli Effect of UV Light Irradiation on Plasticized PVC using Epoxidized Palm Oil
P54 Ady Mara Effect of Calcination Time, OH / Al Ratio, And Keggin / G Suspension on
Natural Bentonite
P56 Miksusanti. Incorporation Lactobascillus Bulgaricus in Edible Coating of Sago Starch and
Analysis of It’s Antibacterial and Organic Acid.
P57 Poedji Loekitowati Effect of temperature and calcination time on hydroxyapatite preparation
Hariani from shells of anadara granosa by hydrothermal method
P58 Gani Purwiandono Analysis Of Heavy Metals In The Sludge Sample Of Bengawan Solo River
P59 Tuty Emilia Agustina Aplication of Fenton-Base Methods for the Treatment of Traditional Fabric
Wastewater
keynote SPEAKERS
Prof. Dr. Basil Shelton Marasinghe, Drs. Muhamad Abdul Kadir Martoprawiro, PhD
Solomon Islands National University, PNG Chemical Society, Indonesia
invited SPEAKERS
Andrew W. Nelson
Computational Chemistry in
Indonesia
invited SPEAKS electrolyte in the DSSC zone, which will have uptake
electron from the counter electrode in catalysis zone. So
in the catalysis zone there will be reduction reaction of
water (proton) to produce hydrogen (acceptor electron
Artificial Photosynthesis for Water from the DSSC zone) and oxidation reaction of water to
Splitting: New Device Type Based on produce molecular oxygen or hydroxyl radical (donor
electron to the DSSC zone). As long as light strike the DSSC
Modified Dyes Sensitized Solar Cell zone the catalysis zone will eventually produce hydrogen.
The above modified DSSC which employing CdS/HOTN
Having Catalysis Zone Extension.
absorb visible light and convert it to energy which induce
a chemical reaction in the catalysis zone to produce
Jarnuzi Gunlazuardi hydrogen from water. In our typical modified DSSC, when
the active counter electrode (semiconductor) was being
Department of Chemistry, Faculty of Science, Universitas employed, the system can split water to hydrogen and
Indonesia, Depok 16424, Indonesia molecular oxygen, by solely visible light, thus a kind of
artificial photosynthesis. The proof of concept and
Water splitting induced by visible light is one of the features for further development will be discussed.
interesting tasks to produce hydrogen (fuel). However to
split water in to hydrogen and molecular oxygen by visible Keywords: Water Splitting; Hydrogen; Titania nanotubes;
light induction is a difficult task. Titania (TiO2 crystal) was Cadmium Sulfide; Artificial photosynthesis
reported being able to split water), but need light with
wave length less than 410 nm. Fortunately, titania can be
composited with other small band gap semiconductor but
has a conduction band level slightly higher (e.g. CdS). The
visible light excites electron of CdS to its conduction band,
that will flow down to the titania’s conduction band.
Supramolecular Ionic Crystals Based
Hence the CdS/Titania system is considered as visible light
active semiconductor composite. Having this system along on Polyoxometalates-Organometallic
with ability to morphologically control of highly ordered
titania nanotubes array film), we developed a system that
Complexes
have a potential to produce hydrogen from water under
induction of visible light. A Highly Ordered Titania Aldes Lesbani*
Nanotubes (HOTN) arrays have been successfully
prepared by electrochemical oxidation of titanium metal Department of Chemistry
sheet in a viscous electrolyte. The electrolyte comprises of Faculty of Mathematic and Natural Sciences
ethylene glycol and water containing fluoride ion. By Universitas Sriwijaya. Kampus Indralaya 30662 Sumatera
varying anodization voltage and time, at certain Selatan, Indonesia
electrolyte composition, a typical tube length (2 - 7 μm) ,
inner tube diameter (40 – 80 nm), and thickness of the *email: aldeslesbani@pps.unsri.ac.id
tube’s wall (10 – 27 nm) can be controlled. The prepared
HOTN then was sensitized by CdS nano particle by a SILAR Polyoxometalates are early transition metal oxygen anions
(successive ionic layer adsorption and reaction) method6). clusters, which have various properties such as acid bases,
The resulting CdS/HOTN showed excellent response redox potentials, shapes and structures, and solubility
toward visible light. The obtained CdS/HOTN then was depending on counter ions. The researches of
employed to construct a modified dyes sensitized solar polyoxometalates are rapidly growing in this decade due
cell (DSSC) having catalysis zone extension. To assembly to application not only in laboratory but also in industrial
the modified DSSC, the HOTN sheet was prepared scales such as supramolecular building blocks, catalysis,
carefully, in which half part of HOTN was sensitized by CdS membranes, adsorbents, and also sensors. In this report,
(hence CdS/HOTN), dedicated as DSSC zone and another polyoxometalates are used as anions in reaction with
half part was leave it uncovered, managed as catalysis organometallic complexes as cations to form
zone. The DSSC zone is a sandwich of CdS/HOTN, supramolecular ionic crystals. Several kinds of
electrolyte (Na2S/S; KCL in methanol water), and Pt/SnO2-F polyoxometalates and organometallic complexes are used
Glass. Upon absorbing light, the CdS in the DSSC produce in order to know the structural effect for formation of
exited electron that flow to titania and subsequently supramolecular ionic crystals. The applications of these
migrate to the catalysis zone. The “hot” electron in the
supramolecular ionic crystals are also addressed especially Immunogenicity Evaluation of
for separation and catalysis.
Recombinant Fim-C S. Typhi Protein
Keywords: ionic crystal, polyoxometalate, organometallic as Typhoid Vaccine Candidate on
complexes
Wistar Rat to Increase the Quality of
Urban Health in Indonesia
The Utilization of Palm Oil as Muktiningsih Nurjayadi1*, Irma Ratna Kartika1, Fera
Kurniadewi1, Nurasiah1, Dwi Arieastuti1 Delia Ayu Wiguna1,
Renewable Block Building Source in Anis Marsella1, Asri Sulfianti 2, Kurnia Agustini2
Chemical Industry 1
Department of Chemistry, Mathematics and Science
Faculty, Universitas Negeri Jakarta
*
Didin Mujahidin K.H. Hasyim Asjhari Building the 6 Floor, Rawamangun
13220, Jakarta, Indonesia
2
Division of Organic Chemistry, Faculty of Mathematics and LABTIAP BPPT-Serpong
Natural Sciences, Institut Teknologi Bandung, Jl. Ganesa
10, Bandung 40132 *email: muktiningsih@unj.ac.id
*email: didin@chem.itb.ac.id Typhoid fever is a world health problem and often occurs
in developing countries, including Indonesia. The cause of
Palm oil is one of the important national commodity and typhoid fever in humans is Salmonella typhi bacteria.
contributes significantly to the national income in Transmission of the disease is generally through a pattern
Indonesia. Modern chemical reaction can modify the palm of life that is less healthy and hygienic. In a previous study,
oil components into fatty acid derived high economic the UNJ Salmonella team had successfully isolated,
value materials, in addition to the palm oil utilization in cloned, expressed, and purified recombinant protein Fim-
food industry, traditional oleochemicals and fuels. Oleic C S. typhi inclusion bodies sized 31 Kilo Dalton (KDa).
acid is the major components in palm oil with a content of Furthermore, these proteins have been used as antigen in
ca. 40%. Ethenolysis of methyl oleate successfully immunogenicity test with ddY mice as test animals and
furnished methyl 9-decenoate and 1-decene via cross give excellent results. This study aims to determine the
olefin metathesis reaction in the presents of Grubbs II immune response of rodent test animals with higher
catalyst. Valorization of methyl 9-decenoat as a new levels against recombinant protein Fim-C S. typhi inclusion
building block have an important role as renewable bodies as antigen. Immunogenicity test was performed
building block on further transformation to produce many using male Wistar rats. That were divided into five test
high-value chemicals. In this presentation, we will show groups: Normal group (control, without injection), Control
the transformation of methyl 9-decenoate in the synthesis Group 1 (injected with PBS), Control Group 2 (injected
of several potential monomers and the synthesis of with Adjuvant FCA/FIA), Samples Group 1 (injected with
civeton. The well-defined strategy on a target-oriented Fim-C Inclusion Bodies S. typhi protein), Samples Group 2
transformation could be a great contribution of organic (Injected with Fim-C Inclusion Bodies S. typhi plus
chemical synthesis in improving the economic value of Adjuvant FCA/FIA protein). The results of the ELISA
palm oil. (Enzyme-Linked Immunosorbent Assay) analysis showed
an increase in antibody titers produced by Wistar rats
Keywords: palm oil, oleic acid, olefin metathesis, after subcutaneous injection with Fim-C protein
renewable building block. emulsified adjuvant or without adjuvant. The result of
analysis by Western Blot method showed the specific
interaction between Fim-C S. typhi antigen with anti-Fim-C
S. typhi antibodies. Data obtained from both methods
confirm that the antigen has a high immunogenicity. It can
be concluded that recombinant protein Fim-C S. typhi
inclusion bodies can be used as a potential vaccine
candidate for typhoid disease. These results are expected
to be an alternative in the discovery of new vaccines that
can improve the quality of life of Indonesian society.
*email : ria.armunanto@ugm.ac.id
Dasril Basir1*, M. Hanafi2, Julinar1, Adi Saputra1, and Tiara *email: sragustini@yahoo.com
Wati1
1
Department of Chemistry, Faculty of Sciences, The The research was intended to characterize mango
University of Sriwijaya, Palembang, Indonesia, powder which produced by small industries. Research
2
Research Center for Chemistry, Indonesian Institute of using randomized complete design with drying
Science, Kawasan PUSPIPTEK Serpong, Tangerang, temperature (50oC,60oC,70oC) as the treatment
Indonesia with 3 replication. Mango used in this research
were varieties mangga harum manis and fillers used were
*email: debasril_chem@yahoo.com sugar at concentration of 20%. The physicochemical
properties of powders produced obsereved were water
This is an our laboratory effort in developing major content, ascorbic acid, color, higroscopicity, flowability,
compounds of F. Fragrans Roxb, Loganiaceae by free index solubility and and total plate count were
solvent reactions between ursolic acid (UA) and its isomer investigated by using the gravimetric method,
oleanolic acid (OA) with n-buthylamine and phenylamine titrimetric, and plate count respectively. While for color
have been conducted by using thionyl chloride as a were ivestigated by using Munsell color system consist
chlorination reagent to make their halide acids of value/lightness, hue angle, and chroma. The results
respectively. In this reaction, the secondary hydroxyl showed that oven drying succesfully produced mango
group at C-3 position was preferably converted to be powder which have water content ranged 2.366 ± 0.576%
olefinic while the carboxyl group at C-28 position was up to 2.938±0.691%, and total plate count 1.65-1.76 log
normally amidated to give N-buthyl-urs-2,12-dien-28- cfu. The highest ascorbic acid content was obtained
amide [N-buthyl-olean-2,12-dien-28-amide] with yield from treatment at 50oC namely 0.146±0.018%. Test on the
45.5% % and N-phenyl-urs-2,12-dien-28-amide [N-phenyl- color showed that mango powder which was dried at
olean-2,12-dien-28-amide] with yield 39%. Cytotoxic 50oC have highest lightness of 75±1.54, chroma of
activity of amidation products toward P-388 murine 41.73±0.23 and hue of 82.27±0.08. The flowability of all
leukemia cells was decreasing about half fold compared to powder indicated fair flow properties (angle of repose
starting material ursolic acid [oleanolic acid]. The IC50 36.95-38.24),higroscopicity of 24.32-25.43%, degree of
values of N-butyl-urs-2,12-dien-28-amide [N-butyl-olean- caking was and index solubility were 97.73%-98.90%.
2,12-dien-28-amide] and N-phenyl-urs-2,12-dien-28-
amide [N-phenyl-olean-2,12-dien-28-amide] were 81, 4 Keywords; mango powder, drying temperature,
μg/mL and 83.6 μg/mL respectively, whereas the IC50 physicochemical properties
value of ursolic acid [oleanolic acid] was 53.4 µg/mL.
1
905- The Effect of Natural Based Oil 907- Identifikasi Geokimia Sumber
as Plasticizer Towards Physics- Daya Unsur Tanah Jarang di Unggan,
Mechanical Properties of Nr-Sbr Sijunjung, Provinsi Sumatera Barat
Blending for Solid Tyre
Ronaldo Irzon*
1* 1
Nasruddin , Tri Susanto 1
Pusat Survei Geologi (Centre for Geological Survey)
1
Balai Riset dan Standardisasi Industri Palembang,
Ministry of Industry Jl. Perindustrian II KM 9, Sukarami, Unsur tanah jarang merupakan sumber daya yang banyak
Palembang, South Sumatera dibahas oleh para peneliti kebumian terkait nilai
ekonomisnya. Studi ini mengungkap indikasi geokimia
*email: nas.bppi@gmail.com kandungan unsur tanah jarang yang cukup besar pada
contoh granit di wilayah Unggan, Kabupaten Sijunjung,
Petroleum derivatives oil has been used dominantly as a Provinsi Sumatera Barat. Jumlah total unsur tanah jarang
primary plasticizer in rubber compounding in tyre pada lokasi yang berada di bagian utara Peta Geologi
industries. Despite its harmful effect to the environment, Lembar Solok ini melebihi 1.300 ppm. XRF dan ICP-MS
it is also a nonrenewable resources that need to be milik Pusat Survei Geologi dimanfaatkan untuk
replaced. Therefore, this research would study the effect mengetahui kadar oksida utama, unsur jarang, dan
of natural based oil such as castor oil, palm oil, Fried - seluruh unsur tanah jarang pada contoh terpilih. Secara
palm oil as an alternative plasticizer to replace petroleum megaskopis, contoh batuan merupakan granit dengan
based oil like white oil and minarex oil in Natural Rubber warna coklat kemerahan, berbutir sangat kasar, dengan
and Styrene Butadiene Rubber (NR-SBR) compounding kuarsa dan feldspar sebagai mineral utama. Contoh
process for solid tire manufacturing. The rubber batuan sebagai granit yang masih cukup segar
compounding used the same amount of each plasticizers dikonfirmasi oleh kandungan SiO2 dan LOI 68% dan 1,05%
which was 8,75 phr in NR-SBR compounding filled by 64 secara berurutan. Indikasi granit peralumina tersebut
phr Carbon Black N330 and 34 phr CaCO3. Physic sebagai tipe A ditunjukkan oleh kandungan Ga, Nb, dan Y
mechanical properties of 5 formulas were examined, the yang tinggi. Bila dibandingkan dengan granit kemerahan
hardness value of 5 formulas range from 68 - 74 ShoreA; lain pada sabuk granit Asia Tenggara, kandungan UTJ pada
tensile strength 118 - 136 kg/cm2, modulus 200% 19,25 – batuan ini tergolong tinggi. Contoh terpilih tergolong pada
31,16; specific gravity 1,22 - 1,29 g/cm3, abrasion seri shoshonitik dengan lanthanum dan niobium sebagai
resistance 102,37 - 135,64 mm3, compression set (tested UTJ utama. Anomali negatif Ce dan anomali negatif Eu
in 25% defl, 70 OC, 22 hours) range from 65,44 to 72,35; merupakan sifat geokimia lain pada batuan plotonik asam
and there were no crack for ozone resistance (tested in 50 dari Provinsi Sumatera Barat ini. Tipe granitoid seperti ini
pphm, 20% strain, 24 hours, 40 OC). In comparison with dianggap layak diteliti lebih jauh untuk dapat
the solid tyre standard requirements, those formulas in menghasilkan nilai ekonomis bagi pendapatan negara dari
this work were complied the standards. To sum up, it is segi sumber daya unsur tanah jarang.
indicated that there is no significant difference in physical
mechanical properties resulted from using either natural Kata Kunci; geochemistry, rare earth elements, granite,
or petroleum based oil as plasticizers. Unggan
2
911- Synthesis and Characterization 912- Isoprenylated flavanone
of Molecular Imprinted Polymer for derivatives and anticancer activity of
Recognition of Atenolol in Biological Macaranga hosei King ex
Hook.F.leaves
Fluids
Eva Marliana1*, Winni Astuti1, Khemasili Kosala2, Rita
Aliya Nur Hasanah*, Shendi Suryana, Driyanti Rahayu,
Hairani1, Tjitjik Srie Tjahjandarie3, Mulyadi Tanjung3
Sandra Megantara, Retna Fauzia, Mutakin
1
Departement of Chemistry, Faculty of Mathematics and
Pharmaceutical Analysis And Medicinal Chemistry
Natural Science, Mulawarman University
Department, Faculty Of Pharmacy, Universitas 2
Padjadjaran, Jl Raya Bandung Sumedang Km 21, Pharmacology Research Group, Faculty of Medicine,
Mulawarman University
Jatinangor, 40611 3
Natural Product Chermistry Research Group, Organic
Chemistry Division, Departement of Chemistry, Faculty of
*email: aliya.n.hasanah@unpad.ac.id
Science, Airlangga University
Atenolol is one of the β-blocker agents as first-line therapy
Four isoprenylated flavanones,named 4’-O-methyl-8-
for hypertension. Long term used of atenolol was
isoprenyleriodiktiol (1), 4’-O-methyl-8-isoprenylnaringenin
reported to increase morbidity and mortality in
(2), lonchocarpol A (3) and 6-isoprenyleriodiktyol (4) have
hypertension patients compared to other drugs. β-Blocker
been isolated from the leaves of Macaranga hosei King ex
are use for heart dysfunction. However, due to the
Hook.f. The structures of four compounds have been
missused possibility, consumption of this drug is strictly
elucidated based on their spectroscopic data, including
regulated in a whole world. Drugs with strict regulation
UV, 1D and 2D NMR, and HREISMS spectra. Compounds
usually exist in complex matrices such as biological fluids.
1–3 displayed anticancer activity toward HeLa cell lines
Regarding that, selective extraction and sensitive
that were evaluated by MTT assay with IC50 values of 6.39,
analytical method are needed to detect and quantify
21.46, 5.62 µM, respectively (compound 4 was not
drugs in such condition. Molecular Imprinted Polymer in
tested). These result indicate that M. hosei has a great
solid phase extraction form can extract and
potential source as anticancer agents.
preconcentrate analyte selectively from the blood. Here,
we wish to report on the development of imprinted
Keywords; Macaranga hosei, anticancer, MTT assay,
polymers using methacrylic acid as receptor monomers.
flavanones, isoprenylated
These compounds have shown an affinity for atenolol in
solution and having a hydrophobic interaction based on
computational approach. The resulting polymers were
capable of selective recovery of >95% of atenolol from
blood and >99% krom urine compared to other drugs that
could exist in the blood.
Keywords; -
3
915- Synthesis and Characterization 916- Pemanfaatan Gliserol Monooleat
of Schiff Base 4,4 Diaminodiphenyl sebagai Plasticizer pada Edible Film
Ether-Vanillin Possessed of Free Gelatin yang Diinkorporasi dengan
Minyak Atsiri Kulit Kayu Manis
Primary Amine
(Cinnamomum Burmanii) sebagai
Ahmad Fatoni1,*, Poedji Loekitowati Hariani2 ,
Antimikroba
Hermansyah2 and Aldes Lesbani2,
Adil Ginting1*, Tonel Barus2, Jamaran Kaban3, Yunazar
1
The High School of Pharmacy Science, Bhakti Pertiwi Manjang4
Jl. Ariodillah 3 No. 22 Palembang 30128 South Sumatera,
1,2,3)
Indonesia Dept.Kimia,FMIPA USU MEDAN,
4)
2
Department of Chemistry, Faculty of Mathematic and .Dept.Kimia UNAND,Padang
Natural Sciences,
Sriwijaya University, *email: adil@usu.ac.id.
Jl. Palembang-Prabumulih Km. 32 Indralaya Ogan Ilir
South Sumatera, Indonesia Dalam penelitian ini telah dilakukan pembuatan edible
film gelatin yang diinkorporasi dengan minyak atsiri kulit
*email: ahfatoni@yahoo.com kayu manis dengan plasticizer gliseril monooleat. Film
dibuat dengan campuran10 g. gelatin dan gliseril
The synthesis and characterization of Schiff base 4,4 monooleat 2.5 g. dan 1g. minyak atsiri kulit kayumanis
diaminodiphenyl ether-vanillin possesed of free primary dalam 100 ml. air setelah dipanaskan , dituang sebanyak
amine has been done. The aims of this research were 45 ml. ke plat kaca ukuran 15 X 15 cm. Aktivitas dari film
synthesis Schiff base 4,4 diaminodiphenyl ether-vanillin diuji terhadap bakteri Escneria coli dan Salmonella sp
possesed of free primary amine from reaction between 1 menunjukkan hasil yang positip. Selanjutnya sifat anti
mol of 4,4 diaminodiphenyl ether and 1 mol of vanillin bakteri film diaplikasikan terhadap ikan tongkol,
which affected by temperature of synthesis and its menunjukkan bahwa daya tahan ikan makin tinggi.
characterization using FTIR spectroscopy and X Ray
Diffraction analysis. The result showed that all product of Kata Kunci; edible film, gelatin, plasticizer, minyak atsiri
Schiff base 4,4 diaminodiphenyl ether-vanillin possesed of kulit kayu manis, antimik
free primary amine. The functional group of –C=N in this
Schiff base compound appeared at wave number 1597
cm-1. The wave number between 3387-3441 cm-1 was
stretching vibration of primary amine (N-H) and stretching
vibration of –C-N from aromatic amine (NH2-aromatic) can 919-Colorimetric and
be found at wave number between 1280-1288 cm-1. Electrochemical Methods for Water
Diffractogram of 4,4 diaminodiphenyl ether, vanillin and
Schiff base 4,4 diaminodiphenyl ether,-vanillin were Quality Test
11.910 - 50.390, 13.130 and 39.990 and 10.130 - 50.60
respectively.
Suherman Suherman1*, Kento Yajima2, Kinichi Morita3,
Toshikazu Kawaguchi2
Keywords; Schiff base, 4,4 diaminodiphenyl ether, vanillin
1
Department of Chemistry Universitas Gadjah Mada
Yogyakarta
2
Hokkaido University Japan
3
Ushio Inc. Japan
6
928- Effect Of Hydrochloric Acid Results showed that the Fe3O4/SiO2/TiO2 nanocomposite
presents optimum activity under UV irradiation for 150
Concentration Toward The Amount minutes. Generally, the photoreduction increased with
And Characteristics Of Gelatin the increase of irradiation time, meanwhile a slightly
decrease was observed for irradiation time more than 2.5
Extracted From Cat Fish Bone hours. Moreover, increasing pH enhanced the
photoreduction and pH that gives highest reduction was 5.
Wega Trisunaryanti*, Iip Izul Falah, Hesty Kusumastuti Kinetic study of its photoreduction shows that the
reaction followed the pseudo-second order with rate
Department of Chemistry, Faculty of Mathematics and constant of 0,0142 g mg-1 minutes-1. The Fe3O4/SiO2/TiO2
Natural Sciences, Gadjah Mada University nanocomposite could reduce Au3+ to Au0 89% under UV
light.
Effect of hydrochloric acid concentration toward the
amount and characteristics of gelatin extracted from cat Keywords; Fe3O4/SiO2/TiO2, nanocomposite,
fish bone Have been evaluated. The cat fish bone was photocatalyst, reduction, Au(III)
pretreated using NaOH 0.1 M for 24 h followed by acid
pretreatment using HCl 1.0, 1.5, and 2.0 M for 1 h to
remove any non-collagenous proteins. The gelatin was
produced by refluxing the pretreated-bone in
demineralized water for 5 h at 70 ℃ then analyzed by FTIR
and SDS-PAGE. The result of gelatin showed that the
pretreatment using HCl 1.5 M produced the highest
amount of gelatin of 13.87 wt.% yield. The SDS-PAGE data
showed that the gelatin had molecular weight range of 9- 938- Fabrication and
298 kDa.
Characterization of Fuel Cell
Keywords; cat fish bone, gelatin, hydrochloric acid, Electrode from Pt-Co/C Catalyst
molecular weight
Dedi Rohendi1, Addy Rachmat1
1*
Jurusan Kimia FMIPA Universitas Sriwijaya
931- Fe3O4/SiO2/TiO2 Nanocomposite One of the most important components in fuel cell is
electrode which hold as center for electrochemical
as Photocatalyst for Reduction of reaction on converting fuel and oxygen into electricity.
Au(III) Ions Special attention hence must be given to this component
in order to achieve high performance especially on its
catalytic activity and durability. To obtain such
Eko Sri Kunarti*, Akhmad Syoufian, Indriana Kartini, Iis performance, some aspect must be take into
Setyo Budi consideration i.e. the content and type of catalyst as well
as preparation method. Impregnation-reduction and
Department of Chemistry, Universitas Gadjah Mada electrodeposition method were evaluated on fabrication
of fuel cell electrode from Pt-Co/C catalyst using
Fe3O4/SiO2/TiO2 nanocomposite has been evaluated as H2PtCl6.6H2O and CoCl2.6H2O in carbon Vulcan XC-72
photocatalyst for reduction of gold (III) ions. The substrate. Transition metal other than platinum as
nanocomposite was prepared by coating TiO2 on supporting catalyst was used not only to enhance catalytic
Fe3O4/SiO2 nanoparticle by using sol gel process followed activity but also to reduced cost and avoid poisoning
by microwave assisted synthesis. Characterization was which platinum suffers easily. Characterization of catalyst
performed by IR spectrometry, X-ray diffraction and using Cyclic Voltammetry (CV) and Electrochemical
transmission electron microscopy methods. Impedance Spectroscopy (EIS) confirmed that catalyst
Photoreactivity of the Fe3O4/SiO2/TiO2 nanocomposite was made from Pt-Co/C using ratio Pt : Co = 2 : 8 has good
conducted under batch systems in the closed reactor catalytic activity for fuel cell application. XRD
equipped with UV light. The photoreduction yield was diffractogram showed result of Pt reduction at 2-theta =
represented as percentage (%) of reduced gold (III) which 39.76° (111) and 46.23° (200) while the present of Co is
was calculated by substraction of initial gold III) not clear at 2-theta = 44.51° and 51.85°. Co was not
concentration by the unreduced one. The unreduced gold detected due to it became an alloy with Pt and relatively
(III) was determined by atomic absorption spectrometry.
7
small concentration (20%). Pt-Co/C catalyst prepared by
impregnation-reduction and electrodeposition methods
can be used as catalyst support in fuel cell electrode
948- Probing of Interaction Mode
Keywords; impregnation-reduction; electrodeposition; Between Cyclic Peptide ADTC3 (Ac-
Pt-Co/C; fuel cell electrode
CAD TPC-NH2) with E-Cadherin
Protein using the Molecular Docking
Method
8
Thr4(HG1) with their distance 2.115 Å, 1.931 Å, and 2.112 Model integrated with Lesson Study while 2nd class as
Å respectively. control class was taught by Conventional model. The
instrument test had been standardized with reliability
Keywords: ADTC3, domain EC1 of E-cadherin, GROMACS, 0.919. The data analysis resulted that the data is normal
Docking. distributed and samples are homogenous. The result data
showed that student’s achievement taught by Project
based learning with lesson study (0.69 ± 0.11) gave higher
significance different compared with student’s
achievement taught by conventional model (0.41±0.08).
949 - Electrooxidation Palm Oil Mill Keywords; Project Based Learning, Buffer Solution topic,
Effluents by Boron Doped Diamond Student’s Achievement
Anode
Salih Muharam*
953- Sintesis Polimer Kolesteril
Pascasarjana Kimia FMIPA Universitas Indonesia
Akrilat
In this work palmitic acid was used as a model compound
of palm oil mill effluent to study the oxidation reaction on Fuji Lestari*
boron doped diamond electrode in aqueous medium.
Experiments have been carried out in continuous
Mahasiswa Kimia Universitas Negeri Jakarta
electrolysis system using boron doped diamond anode
and cyclic voltammetry. The effect of the supporting
Cholesteryl acrylate (KA) is one type of liquid crystal
electrolyte, potential, time and the flow rate of oxidation
cholesteric that has interesting properties that can form a
was studied to removal of palmitic acid as measured as
helical spiral structure that can reflect light. The monomer
the removal of the chemical oxygen demand
phase of cholesteryl acrylate only appears at mesophase
consentration. The result shows that the degradation of
temperature, in order to maintain the helical structure of
palmitic acids by indirect electroxidation at high potential
the cholesterl acrylic compound is polymerized by the UV
in the area of oxygen evolution or the formation of
curing method. The initial stage of synthesis yields the
hydroxyl radicals and it was controlled by mass transfer.
acrylic precursor Acryoxy Butyloksi benzoate (ABB). In the
The degradation of palmitic acid by BDD anode reached
next step, the cholesterolyl acrylate polymer monomer is
87.91%.
then polymerized using UV light with 55 wt of wavelength
which has 365 nm wavelength as well as some advantages
Keywords; Palmitic acid, Palm oil mill effluent, Boron
that emit more efficient UV rays and faster curing time.
doped diamod, Electroxidation
The polymerization process produces a new functional
group formed by C-O esters at 1047 cm-1-1055 cm-1
waves. Further analyzed crystallinity using XRD at
Customs, at minute 10 emerging XRD diffraction pattern
951- The Implementation of Project at 2θ 7.5o and 15o-20o. The result of morphological
analysis using SEM in the lab of UNJ Mofologi Technique
Based Learning Model on Buffer that was produced at minute 20 was seen crosslinked
morphology structure.
Solution
Keywords; Polymerization, UV curing, Polymer Kolesteril
Retno Dwi Suyanti*, Yovy Ardianti Sinuraya Acrylate.
9
956- Lead and Cadmium Mobilization pada permukaan magnetik nanopartikel Fe3O4,
fungsionalisasi permukaan dengan APTES, Pembuatan
from Anas moscha and Cairina magnetik molecularly non imprinted polymer dengan
moschata Tissue using Pineapple mereaksikan EGDMA dan Fe3O4 termodifikasi dengan
inisator Benzoil peroksida. Hasil penelitian menunjukkan
Extract ass Chelating Agents berdasarkan pengukuran dengan FTIR menunjukkan
Fe3O4 terbentuk dari hasil reaksi antara FeCl3.6H2O dan
Pra Dian Mariadi* FeSO4.7H2O, namun berdasarkan hasil SEM Fe3O4 masih
teraglomerisasi walaupun berukuran nanopartikel. Untuk
mengatasi hal ini diperlukan modifikasi dengan silika
[Institutional Affiliation(s)]
menggunakan TEOS. Berdasarkan pengukuran FTIR
menunjukkan bahwa modifikasi dengan silika berhasil
An assesment of dietary risk of heavy metal exposure to
dilakukan, Puncak vibrasi Si–O–Si (simetri), Si–OH dan Si–
humans is important since it is the main source of
O–Si (asimmetri) terlihat pada kisaran 800.46 cm−1, 972.14
exposure. This study aimed to messure the level of
and 1064.71 cm−1. Hasil SEM juga menunjukkan bahwa
contamination of heavy metal especially Lead (Pb) and
bentuk Fe3O4@SiO2 lebih teratur. Fe3O4@SiO2 yang telah
Cadmium (Cd) and the effort to reduce contamination Pb
terbentuk selanjutnya difungsionalisasi menggunakan
and Cd in Anas moscha and Ciarina moschata Tissue. The
APTES agar terbentuk reaksi dengan template dan
concentration of Pb and Cd in Anas moscha and Ciarina
EGDMA yang dapat menghasilkan magnetik molecularly
moschata Tissue lower than the maximum acceptable
imprinted polymer. Berdasarkan hasil karakterisasi
level for Pb and Cd respectively. (1 mg/Kg for Pb; 0,5
mengunakan FTIR menunjukkan bahwa Fe3O4@SiO2
mg/Kg for Cd, SNI 2009). The effort to reduce that heavy
berhasil difungsionalisasi hal ini terlihat dengan gugus NH2
metal using chelating agent citric acid from natural
terlihat jelas dengan adanya vibrasi bending 1570.06 cm−1
organic source using pineapple extract. The highest
dan puncak yang relatif kuat pada daerah 2800–3000 cm −1
decreasing of Pb and Cd level up to 90 % when samples
yang berhubungan dengan vibrasi ulur pita C-H gugus
were boiled in pineapple extract for 1 hour at 1000C. the
metil atau metilen dari APTES. Fe3O4 @SiO2@NH2 juga
study concludes that boiled samples in pineapple extract
dapat digunakan untuk membuat magnetik molecularly
has a potential to reduce the contamination of Pb and Cd.
non imprinted polymer. Hal ini terbukti dengan adanya
gugus C=O pada daerah 1728,22 cm-1
Keywords: Pb, Cd, pineapple extract
Keyword: Magnetik molecularly Imprinted Polymer,
Fungsionalisasi, Template.
10
causing a decrease in specific surface area and increasing 970- Design and Implementation of
the mean pore volume. The transesterification of palm oils
produced 70% of methyl ester under reaction conditions Spectrophotometry for Iodine
700W for 10 min, ratio of mole oil:methanol 1:12 and Determination Based on Flow
weight of catalyst 3 wt%.
Injection Analysis
Keywords: Catalysis
Yeanchon Dulanlebit1*, Muhammad Amran2, Semuel
Unwakoly1, Gloria Bora1
1
Chemistry Program, Faculty of Education and Teacher
967- Isolation of Ethyl P-Methoxy Training, Pattimura University
2
Chemistry Department, Faculty of Mathematics and
Cinnamate Compound from Kencur Natural Science, Bandung Institute of Technology
(Kaempferiagalanga L) Iodine is an element nonmetal and essential micronutrient
needed by human body in a trace amount, iodine
Aliefman Hakim* deficiency may cause brain damage, mental retardation,
cretinism and endemic goiter (GAKI). Analysis method of
Department of Chemistry, Mataram University detecting iodine has widely been used, where iodometry
Kencur (kaempferiagalanga L) is a tropical plant that grows and spectrophotometry analysis is a standard method to
in many areas in Indonesia known as medicinal plants and determine iodine content. The analytical performance of
herbal ingredients by the community. There are many iodine determination with a sensitive and selective flow
secondary metabolite compounds in kencur such as ethyl injection analysis had been developed and evaluated.
cinnamic, paraffin, borneol, karen, p-methoxystyrene and Iodate reacted with the excessive iodide in an acid
ethyl p-methoxycinnamate. The ethyl p- medium to form tri-iodide, which can be detected with
methoxycinnamate compound is known to be the major spectrophotometer at 352 nm. The result of analytical
compound in the kencur plant and is widely used in the performance evaluation of that developed method
cosmetic, asthma and anti-fungal industries. The many indicated a linearity of calibration curve at the range of
benefits of the ethyl p-methoxycinnamate compound 0,1-1,0 mg/L, with the R2 value approached one and
make the need for this compound constantly increasing detection limit is 0,01 mg/L. Through the flow injection
and the need for an isolation method that can produce analysis method, the precision of iodine determination
this compound in large quantities. The isolation method was evaluated, which was revealed as 0,08% variant
used in this research is the soxhletation method using coefficient for the concentration of 0,5 mg/L. This method
ethanol solvent and recrystallization using n-hexane has been successful developed for the iodine
solvent. Samples of kencur were used as much as 50 gram determination in iodized sample, with the recovery
and obtained Crystalline ethyl p-methoxycinnamate as percentage of 102,5%.
much as 0,49 gram with percentage of rendement as
much 0,98%. The resulting crystalline ethyl p- Keywords: iodate; iodine; flow injection analysis;
methoxycinnamate has been identified using UV-vis spectrophotometry; triiodate.
spectroscopy, IR and H-NMR.
12
982-Adsorption of Pb(Ii) using charcoal is 0.95–0.23 Scm-1 and corncob charcoal 0.85–
0.30 Scm-1. Charcoal from coconut shell and corn cobs
Chitosan-Carrageenan Macroporous produced are semiconductors, the increase of activator
Film concentration lowers the value of electrical conductivity.
13
Keywords: science process skills, approach to learning, 993- Oil Recovery Tests by using Bio
the learning of chemistry
surfactant of Indigenous
Pseudomonas peli and Burkholderia
glumae Bacteria From South
Sumatera at various temperature
991- Spectrophotometric conditions
Determination of Boron in Food Bambang Yudono*
Products by Ester Borate Distillation Department of Chemistry FMIPA University of Sriwijaya
Into Curcumin using Sulfuric Acid
The isolates of indigenous Pseudomonas peli and
Catalyst Burkholderia glumae bacteria were obtained from Babat
Toman Village, Musi Banyuasin, South Sumatera which
have a potential as bio surfactant. The bacteria are
Risna Erni Yati Adu*, Roto Roto, Agus Kuncaka
thermophilic bacteria, and then they used to produce bio
Chemistry Department, Universitas Gadjah Mada surfactant by using molase as carbon source. The bio
surfactant were tested their ability to the oil recovery of
Spectrophotometric determination of boron in food soil contained oil 18.64%. The variables of treatments
products by ester borate distillation using sulfuric acid were temperatures from 400C to 800C. The results
catalyst was investigated. This study aims to overcome the showed that the optimal oil recovery by using
sensitivity of curcumin method by generating ester borate Pseudomonas peli and Burkholderia glumae were 2.20%
using sulfuric acid catalyst. Boron was separated by and 18.19% respectively. The results of optimal oil
distillation as triethyl borate and reacted with curcumin. recovery of each bacterium were analysed using gas
Esterification reaction was carried out in a Teflon vessel chromatography to determine the constituent
using ethanol as the solvent and H2SO4 2.5 % (w/w) as the components of petroleum that can be extracted by using
acid catalyst for esterification. Distillation system reached the bio surfactant. The bio surfactant of Burkholderia
optimum condition at temperature of 25 C for 24 hours, glumae dissolved hydrocarbons at a fraction of
pH 5-6, ethanol/boric acid ratio of 5:1. The boron- temperatures 133; 139; 155; 156.8; 165; 173; 190; 197.5
curcumin complex was measured at 555 nm after 10 and 206.3 0C with the total abundance of soluble oil
minutes of reaction. Separation of boron by distillation 25.22%, furthermore the bio surfactant of Pseudomonas
method complied with validation parameters. The peli dissolved hydrocarbons at a fraction of temperatures
standard curve was linier in the concentration range of 133.3; 134; 139; 140; 145 and 150 C with the total
1.2-4.8 ppm (R2=0.9995) and has molar extinction value abundance of soluble oil 16.94%.
(ε) 4.7 x 105 L mol-1 cm-1 for high sensitivity level which is
higher than the previous study, RSD 1.50 % and percent
Keywords: bio surfactant, temperature, oil recovery,
recovery in the range of 96.09-104.92 %. Limit of
Pseudomonas peli, Burkholderia glumae
detection (LOD) and limit of quantification (LOQ) were
0.348 and 1.056 mg/L respectively. Boron content in
sausage, meatball, crackers and tofu products was in the
range of 0.913-3.518; 1.406-3.589; 2.936-4.912 and 0.743-
1.085 mg/kg. Distillation method of ester borate into 995- QSAR, Molecular Docking and
curcumin using sulfuric acid catalyst is suitable for boron
analysis in food products because of its high sensitivity Dynamics Studies of Benzamide
level. Derivatives as Allosteric Inhibitor of
Keywords: - Mitogen Enhanced Kinase
Muhammad Arba*
Faculty of Pharmacy, Halu Oleo University
Mitogen Enhanced Kinase (MEK) is involved in
RAS/RAF/MEK/ERK signaling pathway, which is crucial in
driving cell proliferation. Targeting of the MEK with small
molecules is known to play a role in the inhibition of
14
tumors cell. The aims of this study were to develop a colonies in edible coating before and after covered the
model of Quantitative Structure Activity Relationship grape were 183 and 363 CFU/mL in respectively. The
(QSAR) of some benzamide suitable for prediction of optimum antibacterial activity of edible coating with
benzamide derivatives as potential allosteric inhibitor of probiotic 109 CFU/mL and inhibition zone was 263,76
Mitogen Enhanced Kinase (MEK). The small molecules mm2. Organoleptic test for grape fruit that has been
were divided into training and test set. The selection and covered with edible coating has no influence to panelist
calculation of suitable descriptors was performed by using estimation. Organic acid in edible coating were lactate
molecular operating environment (MOE 2009.10), while acid and acetate acid.
Multiple Linear Regression (MLR) was used to generate
QSAR models. The QSAR models and their validation were Keywords: L. bulgaricius, incorporation, E. coli, probiotic,
performed by statistical application program. The results organic acids, Edible coating
revealed that the validated QSAR model is pIC50 = 14.229
− 0.00001 AM1_E − 0.043 ASA_H − 33.609 Glob + 0.648
Log S + 0.047 Vol. The model satisfies the statistical
criteria with correlation coefficient, leave-one-out
validation coefficient, fischer value, and external 999- Size Distribution of The Silver
validation of 0.931, 0,889, 51.581, and 0.826, respectively.
Using the validated QSAR model, novel compounds were Nanoparticles Synthesized using
proposed. Four new compounds which have lower IC50 Water Extract of Pinus merkusii
were docked into the active site of MEK, in which one of
them demonstrate higher affinity than that of the existing Jungh & De Vriese Cone Flower
benzamide derivative. To check stability of the new
compounds in the active site of MEK, a 30-ns molecular Masruri1*, Isna Noor Azkiya1, Moh. Farid Rahman1, Arie
dynamics simulation are being performed. Srihardyastutie1
1
Keywords: cancer, MEK, benzamide, QSAR, docking Chemistry Department, Brawijaya University, Malang
Silver nanoparticle has many functions in the field of
catalysis and medicine. Controlling the nanoparticle size
and synthesized using a green technique has also paid
attention, recently. The paper reveals recent application
997- Incorporation Lactobascillus of cone flower waste from Pinus merkusii Jung & De
Bulgaricus in Edible Coating of Sago Vriese for environmentally benign method for synthesis
silver nanoparticle. Phenolic groups composed the water
Starch and Analysis of it’s extract was predicted contribute to the reduction reaction
Antibacterial and Organic Acid of silver ion and masking it into nanoparticle. UV-Vis and
FTIR spectra confirmed the nanoparticle, and surface
plasmon resonance (SPR) maxima detected at 455 nm,
Miksusanti*, Dianti Putri, Hermansyah while transmission electron microscope (TEM) revealed
Chemistry Department, University of Sriwijaya the particle size range in between 8 and 23 nm with
spherical in shape.
This research has purposes to analyze antibacterial activity
of edible coating containing probiotic against E. coli using Keywords: green synthesis, silver, nanoparticle, phenolic
well diffusion method. This research used edible coating
from sago starch and L. Bulgarius as probiotic with various
of concentrations (106, 107, 108, and 109 CFU/mL). The
physical characteristic of edible coating, such as color test,
level of water, and viscosity were tested and viability of
probiotic in edible coating before and after covering of
grape surface was calculated. The content of organic acid
in edible coating solution was measured using HPLC
method. Organoleptic testing were color and flavor with
scale A-H involve 30 respondents. Data were analyzed
used SPSS 21. The result of research showed that color of
edible coating change from white to yellow-brown, value
of water level and viscosity were changed from 12% (w/w)
to 22% (w/w) and 393,38 to 293,7 respectively. The
15
1000- Preparation and Effect of for nanoparticle. The phenolic compounds contained in
the water extract is predicted has contribution for this
Adipic Acid on Local Shellac green synthesis. The nanoparticle synthesized is
Modification Based on Material characterized by infrared and ultra violet-visible
spectrophotometry. In addition, the particle size is
Packaging determined by scanning electron microscopy-energy
dispersive x-ray (SEM-EDX) and transmission electron
microscopy (TEM). The result confirms that functional
Nanik Dwi Nurhayati*
group for vibration Zn-O is detected in around 400-600
Pendidikan MIPA, Kimia, Universitas Negeri Sebelas Maret 1/cm, meanwhile surface plasmon resonance (SPR)
maxima is detected at 221,5 nm. Moreover, zinc oxide
This research has aimed to preparation of local shellac nanoparticle is formed as a spherical structure with
local and study to effect of succinic anhydride to local particle size distribution in between 5 and 10 nm. This
shellac modification. Shellac is the purified product of the finding has led the way for further application
natural polymer shellac. It is resinous secretion of the nanoparticle as catalyst for oxidation of alpha-pinene as
insect Kerria lacca. Impurities on local shellac are removed well as for antibiotic composite material application.
by the method of extraction. Hydrolysis was done by
dissolving shellac into NaOH solution and acidification
Keywords: ultra-sonication, green synthesis, zinc oxide,
with HCl. Polyesterification was conducted by reacting
nanoparticle
hydrolyzed shellac with adipic acid used solid state
reaction method. Than shellac was analyzed by intrinsic
viscosity, acid value and Fourier Transform Infrared. The
result showed with the extraction method will be
obtained shellac derived from local shellac.
1006- Distribution of heavy Metals in
Polyesterification through shellac with adipic acid solid
state reaction method, increase concentration of adipic Sediment and Water from coast
acid on shellac have decreased intrinsic viscosity and acid
value. Analysis Fourier Transform Infrared shows the
Batam, Riau Islands, Indonesia
spectra on absorption of the C=O ester groups is stronger
1*
indicated by absorption of C-O ester groups was stronger Suheryanto Suheryanto, 2,3Ismarti Ismarti
too and absorption of the O-H groups is weaker while
1
absorption of the C-H groups is relatively stable. Department of Chemistry, Faculty Math and Natural
Sciences, Sriwijaya University, 30662, Inderalaya, South
Keywords: preparation, modification, shellac, adipic acid, Sumatera, Indonesia; 2International Institute Halal
solid state reaction Research and Training, International Islamic University
Malaysia, Jl. Gombak, Kuala Lumpur, Malaysia;
3
Department of Mathematic, Faculty Teaching Training
and Education, Riau Kepulauan University, Batu Aji Baru
Street, 29438, Batam, Indonesia
1003- Ultrasonication Assisted Green
*email: ismarti78@gmail.com
Synthesis of Zinc Oxide Nanoparticle
The contamination of the aquatic system with heavy
using Water Extract from Cone
metals from natural and anthropogenic source has
Flower Waste of Pinus merkusii become a global problem which poses threads to
ecosystems and natural communities. Heavy metals are
Jungh & De Vriese deemed serious pollutants due to their toxicity,
persistence and non degradability in the environment. The
Masruri1*, Pebri Ari Pangesti1, Moh. Farid Rahman1, Arie increasing pollution by heavy metals has a significant
Srihardyastutie1 adverse health effects for invertebrates, fishes and
1
humans. Cadmium and lead are toxic even at low levels,
Chemistry Department, Brawijaya University whereas copper toxicity requires high doses. This study
Ultra sonication has been studied in order to narrow and aiming to evaluate the environmental status of Coast
reduce a particle size of zinc oxide nanoparticle. Besides Batam, Riau Island, Indonesia based on levels of heavy
that, a cone flower waste of Pinus merkusii Jungh & De metals in seawater and sediment. Sediment and seawater
Vriese has been applied as a reducing and capping agent samples were collected from six sites along west side of
Batam Island. The samples were prepared based on
16
Indonesian National Standard (SNI) then analyzed by an placement of electrodes in separation container. In this
atomic absorption spectrometer (Shimadzu A7000). The study the authors aim to combine the method with
accuracy of the analysis was verified by BAT IM-12 and variation of voltage (1000V - 13000V), electrode distance
BAT IM-13 tracerability to US National Metrology (3 cm - 16 cm) to obtain a minimum separation
Institute. The results showed that cadmium was not percentage of 90% with time under 1 minute in biodiesel
detected in seawater while copper and lead were production process.
detected in seawater. The level of Cu and Pb in seawater
have exceeded environmental quality standard for biota Keywords: Biodiesel, Glycerin Separation, Electrostatic
set by Indonesia Ministry of Environment. The higher level
of heavy metals found in sediment. But the level of heavy
metals in sediment still meet with quality standard of
sediment set by United States EPA, except the level of Cu
in sediment from Sekupang. 1009- Modification of Polyeugenol
Derivate Contain Ethylene Glycol
Keywords: heavy metals, marine pollution, Batam Island, Dimethacrylate (EGDMA) as a Carrier
AAS. for Phenol Transport
17
students in experimental class were enthusiastic and
curious to learn Analytical Chemistry. The students
become familiar to search scientific documents to be used
to complete given tasks. The developed chemistry
learning material with multitask was also improved
student’s ability to write and organize their assignments.
1010- The Development of Innovative
Learning Material with Multitasks to Keywords: Innovative, Learning Material, Analytical
Improve Students Achievement on Chemistry, Anion Analysis, KKNI curriculum
Manihar Situmorang*
1011- Screening and
Department of Chemistry Eduation, Universitas Negeri Characterization of Raw Starch
Medan
Degradation Amylase from Bacteria
Implementation of Indonesian National Qualifications
Framework (KKNI) curriculum at Universitas Negeri Medan Dondang Hot Spring Kutai
bring the change in the teaching and learning style with Kartanegara
aimed to improve student’s competence to adjust with
technology development. The strategy has to be made to
improve students' competence through providing of Winni Astuti*, Rahmat Gunawan, Daniel Tarigan,
innovative learning resources to motivate students to Muhammad Nur Yasin, M. Taufik Asadullah A. Rida'i
learn. This research is aimed to provide an innovative
Department of Chemistry FMIPA UNMUL
chemistry learning material with multitasks to be used as
a learning media to improve students’ achievement on The objective of this research was to screening bacteria
Analytical Chemistry. Development steps are consisted of that produced raw starch degradation amylase from
enriching, innovating and standardizing of a learning Dondang Muara Jawa Kutai Kartanegara hot spring and
material followed by implementation of a developed characterize the amylase. bacteria screening was done by
learning material in the class. Innovation is conducted LB medium containing raw starch and tested with iodine
through integration of relevant contextual examples, solution, protein concentration was determined by
laboratory works, student activities, multimedia, and Bradford method, amylase activity was determined by
hyperlink to trust website onto a learning material. The DNS (Dinitrocalisylic acid) assay. The results showed that
instruction for multitask was also integrated into the the amylase-producing bacteria degrading raw starch was
learning package to guide the students to achieve learning Bacillus sp. The bacteria produced an extracellular
goal. The material was then designed in printed and amylase. The amylase had an optimum pH of 6 and
electronic bases. Research results have showed that good temperature of 50°C. Specific activity of the amylase is
quality learning material equipped with multimedia on the 2893.47 U/mg. The amylase has ability to hydrolyze raw
teaching of Anion Analysis that is suited to KKNI starch of sago, cassava, rice, and corn.
curriculum. Multitasks that are integrated in the KKNI
curriculum are consisted of six tasks, including routine Keywords: amylase, raw starch, Dondang hot spring,
task (RT), critical book report (CBR), critical Bacillus sp.
journal/research report (CJR), idea engineering (IE), mini
research (MR), and small project (PR) to which is relevant
with the Anion Analysis topic being taught.
Implementation of innovated learning material has
showed that the developed material was found to be 1012- Character Education on
effective to improve students’ competence on Analytical
Chemistry. Learning outcome in experimental class that Chemistry Learning Models
has been provided with innovated learning material is
found higher than that in control class with using ordinary Krisna Merdekawati*
textbook. The learning material is found be able to
facilitate the students to learn analytical chemistry easily. Prodi Pendidikan Kimia
Innovated learning material combined with multitask has
One of factor that causes multidimensional crisis in
bring the students moving from lecturer oriented to
Indonesia is the weakening of character. Character
students oriented to study Analytical Chemistry. The
18
education should be a solution in an effort to overcome leaf ash can be used repeatedly as methylene blue
the nation's problems. The implementation of character adsorbent with 100%, 99.5% and 98.5% adsorption
education is very important to be pursued. Character percentage.
education is actually not a new concept in education.
However, its application is minimal. Character education Keywords: Bamboo leaf Ash, SBA - 15, Adsorption,
cannot be separated from any learning material. Methylene blue.
Character education requires a commitment of educators
to be good examples and readiness to give the learning
experience loaded with character. Chemistry as part of
science has potential to develop character. Dimensions of
chemistry are including products, processes, attitudes, 1020- Review: Pollution Due to Coal
and applications. Chemistry learning that involves all
chemistry dimensions is an effective activity to develop Mining Activity and its Impact on
the character of students. There are many variations of Environment
learning models that can be applied in chemistry learning
to develop character. Through literature study, this paper
aims to examine the character content in chemical Andi Arif Setiawan*
learning models. F. MIPA, Universitas PGRI, Palembang Utilization of
natural resources in the form of coal mine has a positive
Keywords: character education, learning models, impact on economic and energy development, in addition
chemistry learning to coal mining activities have a negative impact on the
environment that result in environmental pollution in soil,
water and air. Pollution begins when clearing land, taking
1015- Bio-SBA-15 from bamboo leaf exploitation, transporting, stockpile and when the coal is
burned. When land clearing causes damage to forest
ash for methylene blue adsorption ecosystems. At the time of exploitation impact on air
pollution by coal dust particles, the erosion, siltation of
RR Dirgarini Julia Nurlianti Subagyono*, Anke Rienhar the river, the pollution of heavy metals and the formation
Saputra, Alimuddin Alimuddin of Acid Mine Drainage (AMD). The high acid conditions
cause the faster heavy metals such as Hg, Cd, Pb, Cr, Cu,
Chemistry Department, Faculty of Mathematics and Zn and Ni present in the coal dissolved and carried to the
Natural Sciences, Mulawarman University waters. Coal stockpile activity also causes pollution in the
air, soil, and water. At the time the coal is burned as an
A study on the synthesis and characterization of
energy source causes the emission of hazardous materials
mesoporous silica SBA-15 (Santa Barbara Acid 15) from
into the air of Hg, As, Se and CO2 gas, NOx, SO2. This
bamboo leaf ash and its application as methylene blue
condition has an impact on the environment and
adsorbent has been conducted. SBA-15 from bamboo leaf
ultimately on human health.
ash was synthesized by modification of the micro
emulsion template method. SBA-15 was characterized by Keywords: coal mining; energy; acid mine drainage; heavy
N2 adsorption/desorption analyzer, SAXS (Small Angel X- metal; emission
Ray Diffraction), FTIR (Fourier Transform Infrared) and
SEM (Scanning Electron Microscopy). N2vb
adsorption/desorption analyses showed that SBA-15 has
type IV isotherms, with H1 type hysteresis which was a
characteristic of mesoporous materials. SBA-15 from
bamboo leaf ash has surface area (calculated by BET
method) of 698 m2 / g, pore volume of 0.81 cm3 /g and
pore diameter of 4.66 nm. In the diffractogram appeared
3 typical peaks of SBA-15 between 0.5 - 5o 2θ with miller
indices (100), (110) and (200), respectively. The FTIR
spectrum showed peaks from siloxane (Si-O-Si) and
hydroxyl groups (-OH). The SEM pictures showed that the
morphology of SBA-15 was a combination of platelets and
spheres with the average particle size of 0.5 μm. For
application as methylene blue adsorbent it was found that
the maximum adsorption capacity obtained from the
Langmuir Type 2 equation was 333 mg/g. SBA-15 bamboo
19
1025- Sructural Study of the Ordering 1026- Pumice Stone Coated Mn-N-
Processes of Cold Drawn trans-1,4- TiO2 as Degradation the Linear
Polyisoprene Samples in the Heating Alkylbenzene Sulfonate (LAS)
Process on the Basis of Wide- and
Detergent Waste under The Sunlight
Small-angle X-ray Scattering
Measurements La Ode Agus Salim*, Andi Isar Aliakbar Rafsanjani, Ilham
Ilham, Asep Saputra Taona, La Ode Ahmad
Paramita Jaya Ratri* and Kohji Tashiro*
Abstract Department of Chemistry, Faculty of Science and
1
Department of Chemistry, Universitas Pertamina, Technology, Halu Ole University
Simprug, Jakarta Selatan, Indonesia
2
Department of Future Industry-oriented Basic Science and Pumice stone has a porous surface that can be coated
Materials,Toyota Technological Institute, Tempaku, with a titanium dioxide (TiO2) photocatalyst doped with
Nagoya 468-8511, Japan mangan (Mn) and nitrogen (N) to improve the
photocatalytic performance of visible light. The purpose of
The regularization processes of the TPI glasses drawn at this study was to determine the time needed to degrade
the various low temperatures were investigated by LAS (Linear Alkylbenzene Sulfonate) detergent waste
performing the temperature-dependent simultaneous contaminants by optimally using Mn-N-TiO2 coated stone,
measurements of the 2-dimensional wide-angle and small- and to know the percent degradation of the degraded LAS
angle X-ray scattering patterns. The glassy sample drawn detergent solution using Mn-N-TiO2 in the sun. The
below the cold crystallization temperature but above the method used in this study consisted of four stages, namely
glass transition temperature (-70oC) showed the pumice stone preparation, Mn-N-TiO2 sol gel
disordered form, which was found to transform to the manufacture, pumice coating with Mn-N-TiO2 sol gel and
regular form at aStround -30oC. On the contrary, when degradation process of pollutant detergent waste in the
we decreased the stretching temperature furthermore; sun. Mn-N-TiO2 coated pumice stone degradation process
for example -60 and -70oC, it gave the disordered form. in the reactor presents data that LAS detergent waste can
This disordered form transforms to the regular form by be degraded to 71% within four hours. These results have
heating to around 30oC. The small-angle X-ray scattering the potential to create aquatic environments that are free
patterns were found to change in parallel with the wide- from water pollution, especially laundry waste.
angle X-ray diffraction pattern changes, revealing a
correlation between the crystalline phase transition and Keywords: Pumice stone, Mn-N-TiO2, Photodegradation,
higher-order structure change in these regularization LAS, Sunlight
processes. These paracrystalline are packed in the smaller
crystal cell than the regular form.
Keywords: fragmentation; kaolin; zeolite; cation Study concerning synthesis and characterization of
exchange; NaY zeolite succinic chitosan-hematite-chitosan composite coated
TiO2 for adsorption and photodegradation detergent
waste was conducted. Composites were synthesized
21
through coprecipitation, self-assembly and dip-coating decreasing sulphate (SO42-) at 75% concentration of AMD
methods, where hematite (Fe2O3) was precipitated from as media for water plant but the ability of water plant to
leaching solution of iron sand by the addition of NaOH. decreased sulphate is same level. Interaction between
kinds of water plants with concentration of AMD effect
The aims of study were to know characteristics of the
the percentage of decreasing manganese (Mn), L. flava in
material, effects of concentration and contact time 75% concentration of AMD has the percentage of
toward adsorption and photodegradation detergent decreasing manganese which is high rather than E.
waste. The characterization was conducted by FT-IR, X-RD crassipes and N. olera cea in different concentration of
and SEM. FT-IR showed the existence of succinic chitosan, AMD. By considering its ability of growth in AMD, N.
hematite (Fe2O3), chitosan and TiO2 included functional oleracea has a better capability than E. crassipes and L.
groups of Fe-O, O-H, N-H, C=O, C-O, C-C aromatic and flava.
Ti-O. Analysis of XRD showed existence of hematite
Keywords: Phytoremediation, Water Plants, Acid Mine
(Fe2O3) at 2q = 33,35 and 2Ɵ = 25,27 for TiO2. Moreover,
Drainage, Coal
SEM showed the irregular morphology of composite after
coating with TiO2. The result study showed that the
optimum conditions was 40 minutes for adsorption and
degradation. According to adsorption process, adsorption
percentage up to 76% whereas photodegradation process,
degradation percentage up to 93%. 1040- Synthesis and Characterization
Keywords: Succinic Chitosan-Hematite-Chitosan, TiO2,
of ZSM-5 Zeolite from Dealuminated
adsorption, photodegradation, detergent and Fragmented Bayat-Klaten
Natural Zeolite
23
the fractions was determinated their physical properties 1045- Identification and
include: water content by ASTM D-95 method; ash
content by ASTM D-482 method; flash point C.O.C by Determination of Radioactive
ASTM D-92 method; kinematic viscosity ASTM D-445 Elements in Volcanic Ash of Mount
method and heating value by bomb calorimeter, whereas
tar composition by gas chromatography- spectrometer Sinabung
mass (GC-MS).The result of this research was that both
two fractions was categorized as light bio-oil and heavy
Harlem Marpaung*
bio-oil with each physical properties: specific gravity, 0,99
and 1,13; ash content 0,01 and 0,46 %; kinematic viscosity Departement of Chemistry, University of Sumatera utara
25,5 and 185 cSt; flash point < 27 and 134 C; pH 3 and 2,5;
heating value 10304 and 6210 kcal/kg. Result of analyze The identification and determination of radioactive
by GC-MS show that in the light bio-oil was detected 79 elements in volcanic ash of Mount Sinabung has been
compounds with highest component of phenol 16,4 %, carried out by measuring soil samples taken from several
hydrocarbon compounds of 12,4 %, phenolic of 27,6%, locations using Gamma Spectrometer with HPGe detector.
other oxygenate of 53,6 %, acetic acid of 3%, whereas The radioactive elements found are 232U, 226Ra and 40K
heavy bio-oil was detected 18 compounds with highest with activity concentration of 232U=58,62±2,34,
component of phenol 31,2 %, lauric acid 6,0 %, phenolic 226Ra=20,27±0,96 and 40K=480±12,90 Bq/kg,
of 27,6 % other oxygenat of 35,3 %. respectively. This study aims to evaluate the level of
radioactive elements in soil which useful to establish base
line data after eruption.
Keywords: tar of coconut shell pyrolisis, physical
properties of fuel, shell coconut pyrolysis Keywords: radioactive elements, actively concentration,
spectrometer gamma, volcanic ash, mount Sinabung
This study aims to study the characteristics of moisture Department of Chemistry, University of Sumatera Utara
sorption isotherm of fermented cassava flour by red yeast
In 2017 Indonesia is included in a state of emergency
rice at various fitting models and to determine the best
drug. The field of analytical chemistry contributes to the
fitting model. Samples were analyzed at 303K, 308K, and
determination of the level of narcotics in a fast and easy
313K and equilibrium relative humidity (ERH) from 10%-
to implement. This study aims to optimize the preparation
99% using gravimetric method. The experimental data
and extraction techniques on the determination of
were fitted into five equations e.g. Guggenheim-
methamphetamine levels in shabu-shabu user’s hair using
Anderson-de Boer (GAB), Henderson, Halsey, Oswin and
GCMS Technique and optimize the use of GCMS technique
Chen-Clayton model. The best fitting model was analyzed
on the determination of methamphetamine levels in the
using Mean Relative Determination (MRD) analysis. The
shabu-shabu. The equipment used includes equipment
results showed that GAB model was the best fitting model
commonly used in the Laboratory of Analytical Chemistry,
for 303K and 308K with MRD coefficient 1.98% and 3.11%.
Henderson model was the best fitting model for 313K with Ultrasonic Bath, and Instrument GCMS. The materials
used are methanol, chloroform, and marquist reagents.
MRD coefficient 3.32%.
The sample used is the hair of narcotic users after 14 days
of usage. The optimization of the extraction process has
Keywords: moisture sorption isotherm, cassava flour, red been carried out and the optimal process obtained after
yeast rice the observation is the methanol-chloroform solvent (1: 1)
using the sonication technique. The qualitative test using
marquist reagents produced a brownish yellow sediment.
Based on the results of qualitative tests with 10 (ten) hair
24
samples produced brownish yellow deposits that have to 87.665 ppm, tantalum of 1.5% to 3.819 ppm, and
different intensities. And based on the temperature ratio niobium of 2,1% to 23,060 ppm.
of 40 °C, 50 °C, and 60 C there is a difference in
methamphetamine content. In the comparison of Keywords: tin slag II, Tantalum, Niobium, leaching,
Chloroform and Methanol (1: 1) solvents, the Catechin
methamphetamine content is most prevalent at 50 °C
from 10 samples of shabu-shabu user’s hair. While at 40
°C and 60 °C the methamphetamine content of all samples
has much the same. In the ratio of Chloroform and
Methanol solvents 1: 2 and 2: 1 have the same amount of 1051- Study of Fabrication Anodic
methamphetamine at 40 C, 50 C and 60 C. In this test a
modified column with a column length of 60 m is used. It Aluminum Oxide by Using Two Step
is also reinforced by GCMS data wherein obtained amount Anodization Method
of methamphetamine from user's hair ranges from 0.75 to
1.11 ng mg-1.
Akbar Saputro*
Keywords: examination, narcotics, cannabis, shabu-shabu, Chemistry Department, Universitas Indonesia
gcms
In this research, modification of aluminum surface by
considering the effect of temperature, electrolyte type,
and voltage using two step anodization method so that on
aluminum surface formed aluminum oxide layer. The
formation of anodic aluminum oxide (AAO) used oxalic
acid electrolyte, sulfuric acid electrolyte and electrolyte
1049- Study Interaction of Catechin oxalic acid mixture with sulfuric acid. The optimum
Extract (Camellia sinensis) with conditions in the formation of AAO by using 0.3 M oxalic
acid mixed electrolyte with 0.1 M sulfuric acid obtained
Tantalum and Niobium Gradual pore diameter ± 76.32 nm and pore distance ± 33.56 nm.
Leaching Product of Tin Slags II Variations of voltage are performed to determine the
effect of voltage in pore formation. The use of 25 V
voltage with a concentration of 0.3 M sulfuric acid with a
Widiantari Nofriandani*, Agustino Zulys
pore of ± 57.72 nm and a pore spacing of ± 30.52 nm. The
Department of Chemistry, Universitas Indonesia use of 45 V voltage in oxalic acid 0.3 M obtained pore
diameter ± 97.37 nm and pore spacing ± 30.97 nm,
Tin slag II is a by-product of tin processing which contains whereas in 0.3 M oxalic acid mixed electrolyte with 0.1 M
iron oxide, calcium oxide, tantalum oxide, and niobium sulfuric acid was obtained by pore diameter ± 76.32 nm
oxide and the others. Tin slag II has tantalum oxide and and the distance between Pore ± 33.55 nm using only 25 V
niobium oxide levels of 0.33% and 0.64%, respectively. voltage. This shows the addition of sulfuric acid in oxalic
The extractions of Tantalum and Niobium from tin slag II acid gives effect to the voltage used to give effect in the
were performed using gradual leaching method with 6 M formation of anodic aluminum oxide.
sodium hydroxide followed by addition of 3.25 M
hydrochloric acid and the resultant mixtures was left for
Keywords: aluminum, two step anodization, and anodic
15 minutes at 50 C. Then, leaching was continued using aluminum oxide
fluoride acid with variated concentration, this resulted in
optimum concentration of fluoride at 4 M with
concentration of tantalum and niobium of 3.879 ppm and
23.109 ppm and most dominant impurities constituent
iron of 99.879 ppm which characterized using Microwave
Plasma -AES. The isolation of catechin from green tea leaf
Camellia sinensis was conducted as well. Isolated catechin
was used as a complexing agent for Tantalum and
Niobium so that the impurities in tin slag II can be more
easily extracted. However, it can be seen that the
catechins are more likely to bind to iron which is
impurities on tin slag II compared to Tantalum and
Niobium, based on decrease in iron concentration by 12%
25
5052- Extraction and and adsorption. Manufacture of additives based on US
Pat. 5.826.369. Where, chlorophyll and carotene extract is
Preconcentration of Zinc(II) Ion by mixed with Fame and solvent (xylene and gasoline) in a
Fatty Hydroxamic Acids Immobilized particular composition. The characterization of pigment
was performed using UV-Vis spectroscopy. In this study,
onto Zeolit there were 3 variations of additive with ratio of
chlorophyll and carotene extract are (0: 1), (3: 1) and (2: 3)
to be formulated in gasoline. Performance testing of
Dedy Suhendra*, Erin Ryantin Gunawan, Firman Ozaki
additives in gasoline include the physical-chemical
Department of Chemistry, Faculty of Mathematics and properties, octane number and exhaust emissions,
Science, University of Mataram including hydrocarbon, carbon monoxide and carbon
dioxide. The results showed the addition of additives from
Mining in Indonesia contributes significantly to mineral chlorophyll and carotene extract into gasoline which can
supplies nationally, but illegal mining activities can cause give rise octane number of gasoline seen in additive with
natural destruction, habitat loss and loss of biodiversity. ratio (2: 3) with small increase (0,3%). However, the
This is because only the main metal, which is the gold results of the analysis of the hydrocarbons composition of
taken while the other metal is discharged into the drain as the formulated gasoline (paraffin, iso-paraffin, aromatic
waste. One of the metal ions to be waste is the zinc(II) ion. and olefin) showed that the additive with the ratio of
A method of zinc(II) ion extraction from other ions by chlorophyll and carotene (2: 3) gave the highest increase
using a column containing fatty hydroxamic acids – loaded in olefin content (22.9%). The results of emission test
zeolit (FHA-Zeo) is described. Several factors, which affect showed that the use of additives with a ratio of carotene
the extraction efficiency such as pH, sample volume, and greater than chlorophyll in gasoline can reduce
concentration of eluent and flow rate, have been Hydrocarbon emissions by 30.9%. These results indicate
investigated. The maximum sorption capacity of FHA-zeo that the use of additives with the ratio of chlorophyll and
obtained was 88.38 mgg-1. A quantitative recovery of carotene (2: 3) can improve the performance of gasoline
zinc(II) ion from FHA-zeo column was obtained using 10% fuel better than 2 other additives. The blending results of
HNO3 solutions as eluent with a preconcentration factor of all additives with gasoline, showed no significant change
60. A method for separation of zinc(II) from lead(II) is in physical-chemical properties.
proposed. A rapid sample throughput, a clean separation,
a high preconcentration factor and simplicity are the main Keywords: chlorophyll, carotene, gasoline, octane
advantages in these analytical procedures. booster, exhaust emission
Generally, octane booster additives of gasoline that have a Lipase is one hydrolase enzyme that has an important role
good effect increase come from organometallic in the biotechnology industries. This is due to its ability to
compounds such as TEL and MMT. Alternative substitutes catalyze multiple organic reactions such as hydrolysis,
of TEL and MMT as octane booster additives should be esterification, interesterification, transesterification and
sought for environmental considerations. In this study synthesis reactions. Research for inventing novel lipase
used vegetable materials are extracts of chlorophyll from with unique properties is still being carried out by using
water hyacinth (eceng gondok) and carotene extract from several approaches. One of the method is by
CPO. The methods used in the extraction are Maceration
26
metagenomics approach which is directly amplifying lipase (FTIR). The result revealed that equilibrium time is found
gene from natural resources. The lack signal peptide lipase to be 2 hours in the form of spherical shaped particles,
is a lipase from compost obtained by metagenome porous structure with cracks and crevices. Infrared
approach, encodes 280 amino acids with molecular mass spectral data supported the presence of functional group
at around 31 KDa. This lipase shows 97% identity at amino in activated carbon. The possible mechanism of
acid level with lipase from Pseudomonas stutzeri adsorption on these absorbents has also been included to
(AID66451.1) strain BK-AB12. Here we report, attempt providing the future perspective of low cost
characteristic of lack signal peptide lipase. The method adsorbents that effectively removes PAHs from aqueous
includes production of lack signal peptide lipase in environment.
Escherichia coli BL21 cells to obtain crude extract.
Characterization was performed on crude extracts Keywords: polycyclic aromatic hydrocarbons, activated
including determination of optimum pH, temperature and carbon, rice husk
substrate specificity. The results showed that lack signal
peptide lipase has an optimum activity at pH 8,
temperature 90 ° C. This lipase showed activity at various
length of carbon chain with optimum activity to
paranitrophenil myristate (p-NPM) substrate.
27
1071- Synthesis of Sorbitan Fatty 1073- The Anti-Fungal Effect of
Acid Esters as Ligand for Zn2+ and Candida Albican cause "Candidiasis"
Pb2+ Metal Ions in Industrial Sludge in Various of Liquid Substances with
from Tegal Zno Nanoparticles and TiO2
Combination as Active Ingredients
Raedhita Arya Kanigoro*, Agustino Zulys, Misri Gozan
Department of Chemistry, Universitas Indonesia Evi Maryanti*
Sorbitan fatty acid ester is a surfactant made from Department chemistry, Faculty of Mathematics and
esterification reaction of sorbitan and fatty acid. Sorbitan Natural Sciences, The University of Bengkulu
stearate and sorbitan oleate have a potential as metal
ligand due to their hydroxyl groups and because of their
A liquid soap formulation study was made from a
non-polar properties. In this research, synthesis of
combination of ZnO nanoparticles and TiO2 to overcome
sorbitan stearate and sorbitan oleate were carried out
Candida albicans fungus by varying ZnO nanoparticles and
using sorbitol and catalyzed by H2SO4 and NaOH. Synthesis
TiO2 at various concentrations. This study aims to see the
of both sorbitan esters were done in two steps, the first
anti-fungal effects of ZnO nanoparticles and TiO2 after
step was dehydration of sorbitol and then esterification.
formulated into liquid soap. Liquid soaps are made using
The products of the reaction were characterized using
TEA soap bases, stearic acid and glycerin. Antifungal test
FTIR and the acid values were also evaluated. Later on, the
of Candida albicans fungus with disc diffusion method.
sorbitan esters ability to bind with metal ions was studied
Evaluation of liquid soaps includes organoleptic test,
using AAS to analyze the concentration of metal ion
determination of density, viscosity examination, pH test,
solution. The complex formation study was done with
and anti-fungal effect test. The results showed that ZnO
Job’s Method using UV-Vis Spectrophotometry. We also
nanoparticles and TiO2 were formulations in liquid soap
studied the use of sorbitan esters as ligand for metal ions
form and were physically stable. The anti-fungal effect
in solution of industrial sludge from Tegal. The sorbitan
test showed that F4 with ZnO concentration of 2.5% had
ester products has acid values of 25,45 mg/g and 65,9
strong anti-fungal activity with 12.4 mm inhibition
mg/g for sorbitan stearate and sorbitan oleate
diameter.
respectively, with 14,94% and 33,19% free fatty acids.
Compared to sorbitan oleate and Span 80, the sorbitan
stearate product has the best potential to be use as Keywords: -
ligand, as it can bind up to 30,5% of Zn2+ ion and 42% of
Pb2+ ion from destruction solution of Tegal’s industrial
sludge with the optimum condition: contact time 2 s, pH
1, and metal : ligand volume ratio is 2 : 1.
1075- Green Synthesis of SnO2
Keywords: sorbitan esters, sorbitol, esterification, Nanoparticles in Aqueous Leaves
dehydration, ligand, Zn2+, Pb2+
Extracts of Kalanchoe Pinnata by
Hydrothermal Method
29
1084- Synthesis of Methyl Cinnamat as variable of reaction. Several characterization
techniques of HAp were done to analyze the
Derivatives as Anticancer Candidate hydroxyapatite synthesized. The XRD pattern of
hydroxyapatite synthesized revealed that HAp can be
produced using both of the solvents. The specific peak of
Dwi Marwati Siswanti*
HAp appeared. The Schererr equation was used to
Chemistry Departement, Universitas Mathla'ul Anwar estimate the crystal size of HAp prepared, and the result
proved that nano-crystalline of HAp can be produced. The
Synthesis of methyl cinnamate derivatives have been functional group of hydroxyapatite compounds was also
performed to increase its biological activity in the search analyzed by FTIR instrument. The hydroxyapatite obtained
for anti-cancer agents. Synthesis begins with the reaction have characteristics band exhibited in sample spectra. For
of hydrolysis of methyl cinnamate to cinnamic acid to analyzing the morphology and specific surface area were
increase functional group reactivity. This reaction yields done by SEM-EDX respectively. The synthesized HAp can
70% yield. The resulting sinnamic acid will then be used be a potential material for several applications.
for further reactions. This second-stage reaction uses an
amidation method with p-toluensulfonic acid catalyst
Keywords: CaO, Geloina Coaxans shell, solvents
(pTSA) and aniline addition, yielding N, 3-diphenyl-3
(phenylamino) propanamide with 3.2% yield. Other
second-stage reactions use N, N dicyclohexyl carbodiimide
(DCC) and N, N4-dimethyl amino pyridine (DMC) catalysts
as activators to produce compounds that resemble
dimeric cinnamates (1E, 4E) 1.5 diphenylpenta-1,4-dien -
1088- Isolation of Β-Chitosan from
3-one with 7.8% yield. Toxicity test of methyl sinnamate, Squid Bone as Raw Material to
acetic acid, N, 3-diphenyl-3 (phenylamino) propanamide
and (1E, 4E) 1.5 diphenylpenta-1,4-dien-3-one using brine
Synthesize Hybrid Photocatalists
shrimp lethality test (BSLT) LC50 respectively 144.21; TiO2-Chitosan
169.82; 65,17; And 93.95 ppm. The result of cytotoxicity
test using MTL method on HeLa cell (ATCC CCL2) on N, 3-
diphenyl-3 (phenylamino) propanamide and (1E, 4E) 1.5 Risfidian Mohadi*, Nurlisa Hidayati, Aldes Lesbani
diphenylpenta-1,4-dien-3-one obtained IC50 133, 12 and Dept. of Chemistry, Faculty of Mathematics and Natural
5.94 ppm. Methyl cinnamate derivatives have higher Science, Sriwijaya University, Ogan Ilir, South Sumatera
activity with increasing lipophilic properties. 30622, INDONESIA
30
1089- Synthesis and Characterization 1093- A new bisbenzylisoquinoline
of Membrane Support from Al-Cu alkaloid from the roots of
Pillared Clay Pycnarrhena cauliflora with cytotoxic
activities
Adi Darmawan*, Siti Shafalisa
Chemistry Department, Faculty of Sciences and Masriani Masriani*
Mathematics, Diponegoro University, Tembalang,
Chemistry Department, Universitas Tanjungpura
Semarang
A new bisbenzylisoquinoline alkaloid, 6-methoxy, 6’,7,12-
The manufacture of membrane support from the Al-Cu
trihidroxy berbamane was isolated from the roots of
pillared clay has been conducted. Al-Cu pillared clay was
Pycnarrhena cauliflora. The structure was established by
made by mixing Al-Cu pillared solution into clay
spectroscopic methods, including HR-ESI-MS, FT-IR, and
suspension. The molar ratio of Al and Cu was 8:2 whereas
NMR techniques. The compound exhibited potent
the molar ratio [OH]/[Cu+Al] = 2.2. The clay suspension
cytotoxic activities against five human cancer cell lines
was dried at 60°C for 5 hours and then calcined at 200°C,
(T47D, MCF-7, HeLa, Raji, and WiDr) with IC50 value less
300°C and 400°C for 4 hours with a ramp rate of 1°C/min.
than 4 μg/mL and high selectivity with SI more than 3.
The resulting pillared clay was then characterized by XRD
and GSA and molded into membrane support. Membrane
support was then tested for dye filtration. The X-Ray Keywords: Pycnarrhena cauliflora, bisbenzylisoquinoline
Diffraction (XRD) results showed that the natural clay had alkaloid, cytotoxic activity
a basal spacing (d001) of 15.08 Å. While the pillared clays
had basal spacing of 17.34 Å, 16.05 Å, 16.37 Å and 15.62 Å
for heating temperature of 60°C, 200°C, 300°C and 400°C
respectively. However, the diameter of the Al-Cu pillared
clay was (38 Å) which was greater than that of natural clay 1096- Antibacterial and Xanthin
(34 Å). Meanwhile, the surface area of membrane support Oxidase Inhibition Power of Peanut
was 50.48 m2/g that was almost the same as natural clay
of 52.45 m2/g. The methylene blue filtration process (Arachis Hypogaea L.) Peel Ethanol
showed the clear-color filtration results in all Extract
concentrations. Measurements using the UV-Vis
spectrophotometer produced a rejection value of up to
99.92% and increased as concentration enlarged. Subandi Subandi*
Meanwhile, the water flux value was up to 3.51 x10-6 Kg Chemistry Department, Faculty of Math and Science, State
min-1 and decreased with the increasing of concentration. Univ. of Malang
Based on this research, Al-Cu pillared clay could be used
as base material of membrane support especially for The aims of this study are to determine the types of
ultrafiltration and when applied as filter, it could get secondary metabolite compounds, antibacterial and
filtration purity up to 99.9%. xanthine oxidase inhibitory power of peanut skin extract.
Research subjects were epidermis and outer peel of
Keyword: - peanut seed. The research stages include peel preparation
and ethanol extraction, phytochemical test, antibacterial
and inhibition test. The results showed that peanut
epidermis extract contained tannins, polyphenols,
flavonoids, alkaloids, and terpenoids, and peanut outer
peel has the same content, except tannins. At the
concentration of 100 ppm, the antibacterial activity of
peanut peel extracts was proportional to amoxicillin, while
the inhibitory power of epidermis and peanut outer peel
extracts of 100 ppm are equivalent to 12 and 14 ppm
allopurinol, respectively.
31
1097- The Influence of Distillation 1100- Preparation and Effect of
Time on Component Profile of Adipic Acid on Local Shellac
Essential Oil of Key Lime (Citrus Modification Based on Material
aurantifolia (Christm.&Panz.) Packaging
Swingle) Leaves and Its Antibacterial Nanik Dwi Nurhayati1*, Karna Wijaya2, Triyono3, Eddy
Activity Against Staphylococcus Heraldy4
32
1102- QSAR, Molecular Docking and 1104- An Efficient Method on
Dynamics Studies of Pyrrolo[2,3- Acetylation of Eugenol with Acetic
b]pyridine Derivatives as Bruton’s Anhydride Catalyzed by Sodium or
Tyrosine Kinase Inhibitors Potassium Bicarbonates
33
due to the presence of bamboo fiber has a high content of 1107- X-Ray Diffraction Analysis on
cellulose that can to replace the failure in pineapple leafs
and coconut fiber and make the hybrid composites not Effect of Time Reaction and Alkali
only as a strong material but biodegradable too. Concentration in Merlinoite
Keywords: Flexural Strength, Hybrid Composite, Natural Eddy Heraldy*
Fiber, SEM, Tensile Strength
Chemistry Department, Faculty of Mathematics and
Natural Sciences, Sebelas Maret University, Surakarta
35
1113- Determination of Morphine in handle phenol waste is photocatalysis. This study aims to
examine the effect of pH and the duration of irradiation
White Rats Blood (Rattus Norvegicus) on the degradation of phenol compounds using TiO2-
Using Gcms Chitosan thin film photocatalysts. The synthesis of thin
layer photocatalysts was prepared by dip-coating method
on glass preparation media. TiO2 is characterized by XRD
Muhammad Taufik1*, Rid Wanto2, Harlem Marpaung3, Zul
and SEM. TiO2-Chitosan thin photocatalyst activity was
Alfian3, Hamlan Na'im1, Mariany Razali1
tested using 100 mg / L phenol solution with pH 4, 6, 8,
1 10, and 12 on UV irradiation. In the study of the effect of
Prodi Farmasi STIKes Nurliana (Stikna) Medan
2 radiation duration, the time used was 1, 2, 3, 4 and 5
Prodi Famasi UMN Al Wahliyah Medan
3 hours at the optimum phenol pH that is pH 8. Phenol
Pascasarjana Kimia USU Medan
concentration was determined by UV-Vis
spectrophotometer at wavelength 269.7 nm. The XRD
Morphine is an opioid analgesic that binds to the Central
characterization results show that TiO2 is used in anatase
Nervous System receptor that affects the perception and
structure. The SEM results show that TiO2 has a hollow
response to pain. According to RI Law no. 35 Year 2009,
surface structure. Based on statistical test results obtained
morphine belongs to the narcotic section of class II which
information that the optimum pH of phenol is pH 8, and
is commonly used in therapy and scientific development
duration of optimum irradiation obtained at the 5th hour
which has high potential to be misused and can cause
with degradation of 33.85%.
dependence. In 2017, Indonesia proclaimed as one of the
countries of emergency Drugs so it takes the help of
Keywords: degradation, photocatalyst, thin layer TiO2-
collaborative thinking in the field of Forensic Chemistry,
Chitosan, phenol, UV rays
especially for identification of drugs in the laboratory. This
study aims to determine morphine compounds contained
in the blood of male white rats (Rattus norvegicus) that
have been injected using GCMS. Descriptive method was
developed by extraction process using methanol and
chloroform solvent (1: 1) and experimental method was 1116- Colorimetric Analysis of
developed by performing treatment of morphine Hypochlorite Ion by Using Ag
concentration injected with concentration 0%, 1%, 2%,
3%, 4 % and 5%. Injection was performed subcutaneously Nanoparticles
and blood sampling after 3 (three) hours after injection.
The qualitative identification using the marquis reagents Roto* and Savytri I.D. Puspitasari
yields morphine at 0% is negative, at 1%, 2% and 3% are +
(slightly), and at 4% and 5% are ++ (moderate). Department of Chemistry Universitas Gadjah Mada
Identification using GCMS resulted in morphine levels Yogyakarta Indonesia
ranging from 0.20% to 0.42%.
*email: roto05@ugm.ac.id
Keywords: Determination, morphine, white rats blood,
GCMS Colorimetric analysis of OCl- ion in water has been
conducted by using Ag nanoparticles. AgNO3 solution was
reduced chemically by ascorbic acid in PVA solution as a
stabilizing agent, stirred for 1 hour at 80 oC. The structure,
shape, and size of the nanoparticles were confirmed with
1114- Effect of pH Phenol on The XRD and TEM. The resulting Ag nanoparticles have fcc
Ability of Thin Layer Photocatalyst crystal structure with a lattice parameter of 4.073Å. The
colloid of Ag nanoparticles shows UV-Vis absorption peak
TiO2-Chitosan to Degrade Phenol at 421-422 nm. The Ag nanoparticles synthesized at an
with UV Light initial concentration of 100 and 200 mg/L have an average
diameter of 41 and 46 nm, respectively. The addition of
0.001-10,000 µg/L OCl- caused the surface plasmon (SPR)
Sri Wardhani* absorbance of colloidal Ag nanoparticles to decrease
greatly but did not change the absorption peak. A
Kimia FMIPA UNIVERSITAS BRAWIJAYA decrease in SPR absorbance is believed to be due to the
surface interaction between the nanoparticles and the
Phenol waste can cause problems if not processed. One anion added. This very sensitive detection method of
effect is environmental pollution. The method used to
36
could be very useful in the monitoring hypochlorite in
drinking water.
Austrian-Indonesian Center for Computational Chemistry Synthesis of N-formyl-2-pyrazoline derivatives and its
Universitas Gadjah Mada, Yogyakarta, INDONESIA antibacterial activity test have been carried out. The
synthesis of pyrazoline was performed via cycloaddition of
*email: harnodp@ugm.ac.id 1-(2,4-dihydroxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-
on (chalcone) by reaction with hydrazine monohydrate in
Study of substituents effect and solvation on acidic condition. Chalcone was synthesized from p-
semiconductor properties of Zn(II)-Porphyrin complexes anisaldehyde by reaction with 2,4-dihydroxy
had been performed base on Density Functional acetophenone via Claisen Schmidt aldol condensation.
Theory/Time Dependent-Density Functional Theory Chalcone was synthesized from p-anisaldehyde using KOH
(DFT/TD-DFT) method. The aim of this research was to 40% (w/w) under stirring at room temperature for 48 h.
determine the substituen effect on band gap energy (Eg), Synthesis of 1-formyl-3-(2,4-dihydroxyphenyl)-5-(4-
Density of States, and electronic absorption spectra with dimethoxyphenyl)-2-pyrazoline were performed by
IEFPCM solvation. Geometry optimization was performed refluxing chalcone with hydrazine monohydrate in formic
in order to obtain molecular structure, electronic acid for 6 h. All the synthesized compounds were
structure and energy profile using DFT/B3LYP/LANL2DZ characterized using FTIR, GC-MS and 1H-NMR
with water IEFPCM solvation. Optimized structures were spectrometers. All the pyrazolines were screened for their
then used as the input for the calculation of DOS and antibacterial activities by agar well-diffusion against Gram
electronic absorption spectra using TD-DFT method. positive (Staphylococcus aureus, Bacillus cereus, Bacillus
Computational results showed that complexes substituted subtilis) and negative (Escherichia coli, Shigella flexneri)
with electron donating or withdrawing groups have bacterial, tetracycline (100 ppm) as positive control and
relation on band gap energy, density of states and dimethylsulfoxide (DMSO 99.9%) as a negative control.
electronic spectra. The Zn(II)P-NO2 was recommended to The result showed that chalcone had been successfully
semiconductor with band band gap energy 2.45 eV. synthesized in 38% yield, while the cycloaddition reaction
IEFPCM solvation give an effect on magnitude of EG yielded the pyrazoline in 88%. Pyrazoline showed
Zn(II)P-R and comparable to experimental result. The band antibacterial activity against Gram-positive bacteria and
gap energy and DOS abundance of occupied orbital Gram negative bacteria. The highest activity showed by its
however is decrease for the complexes with electron zone of inhibitions(mm)/concentration(ppm) against B.
donating group. cereus (5,75/1000) and Gram-negative E. coli (3,75/1000).
Keywords: semiconductor, Zn(II)-Porphyrin, substituent Keywords: N-formyl-2-pyrazoline, chalcone, anise seed oil,
effect, solvation p-anisaldehyde, antibacterial
37
1120- Synthesis of N-
Acetylpyrazoline Derivative from
1119- Isolation and Structure Veratraldehyde and 5-Bromo-2
Elucidation of A New Naturally Hydroxyacetophenone and its
Isolated Compound from Sesbania Cytotoxicity Test Against some
grandiflora Cancer Cells
Noviany Noviany1*, Sutopo Hadi1, Muhammad Aziz2
Tutik Dwi Wahyuningsih1*, a), Endang Astuti1 and Islah
1 Muttaqiin1
Department of Chemistry, Faculty of Mathematics and
Natural Sciences, University of Lampung, Bandar 1
Department of Chemistry, Faculty of Mathematics and
Lampung, 35145, Indonesia
2
Institute of Innovative Research, Tokyo Institute of Natural Sciences, Universitas Gadjah Mada, Sekip Utara
Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152- BLS 21, Yogyakarta 55281, Indonesia
8550, Japan
*email: tutikdw@ugm.ac.id
This study aimed to isolate and purify the secondary
metabolites from the ethylacetate extract of Sesbania Synthesis of N-acetylpyrazoline derivative from
grandiflora stembarks. In a previous study, we described a veratraldehyde and 5-bromo-2-hydroxy acetophenone
new naturally binaphtol compound which successfully and its cytotoxicity test have been carried out. The
isolated for the first time from the root of S. grandiflora. synthesis was performed in several steps, i.e.,
As a part of our continuing investigation, we now report bromination, aldol condensation, and cyclization
the isolation and identification another new phenolic reactions. The first step, 5-bromo-2-hydroxyacetophenone
obtained from the stembark of S. grandiflora. The was synthesized via green bromination of 2-hydroxy
structure elucidation of the purified compound was acetophenone using KBrO3, HBr 47% and glacial acetic
conducted by using one- and two-dimensional nuclear acid. The second step, aldol condensation of 5-bromo-2-
magnetic resonance, ultraviolet and infrared hydroxy acetophenone and veratraldehyde using NaOH
spectroscopy, and electrospray ionization time-of-flight 40% (w/v) under stirring for 48 h produced the related
mass spectrometry. To our knowledge, the isolated chalcone. Finally, synthesis of N-acetylpyrazoline was
compound was found as a new naturally occurrence of conducted by refluxing the chalcone and hydrazine
phenolic type from the Leguminosae plant for the first hydrate using glacial acetic acid in 24 h. The structure
time particularly from S. grandiflora. elucidation of all products was confirmed by FTIR, GC-MS,
Direct-MS, 1H- and 13C-NMR Spectrometers. N-
Keywords: new naturally isolated, phenolic compound, acetylpyrazoline was evaluated for cytotoxicity against
Sesbania grandiflora, structure elucidation WiDr, HeLa, T47D, and MCF-7 cancer cell lines and also its
selectivity to Vero normal cell line by MTT assay. The
result showed that chalcone was produced as bright
orange solid in 83.98% yield and m.p of 166.50-167.80 ºC,
while N-acetylpyrazoline as green-brownish solid was
yielded in 66.67% with m.p of 151.50-153.80 ºC.
Cytotoxicity test showed that N-acetylpyrazoline had
moderate cytotoxicity against WiDr, HeLa, T47D and MCF-
7 cancer cell lines with IC50 values 50.95; 97.84; 52.40;
152.87 μg/mL, respectively. N-acetylpyrazoline is selective
against Vero normal cell line with the value of 267.84
μg/mL.
38
aqueous solution. The aims of the research are preparing
BNC and studying protein adsorption behaviors in various
pH and ionic strength. Preparation of BNC was carried out
1121- Synthesis and Anticancer Assay by acid hydrolysis method. Meanwhile, study of protein
of N-Hydrogen Pyrazoline from 2,4- adsorption used bath method with Bovine serum albumin
as the protein model. The result shows that BNC prepared
Dihydroxyacetophenone and P- well by acid hydrolysis method due to the increasing of its
Anisaldehyde conductivity. Calculation predicted around 312,0 mmole
Kg-1 sulfonat group introduced to the backbone of
Tutik Dwi Wahyuningsih1*), Deni Pranowo1 and Niken bacterial cellulose (BC). XRD analyses showed that
Hastuti1 crystallinity of BNC was greater than BC. Application to
protein showed that BNC has higher adsorption than BC in
1
Department of Chemistry, Faculty of Mathematics and any various pH and ionic strength. The protein adsorption
Natural Sciences, Universitas Gadjah Mada, Sekip Utara was decreased on both BNC and BC by increasing pH as
BLS 21, Yogyakarta 55281, Indonesia well as ionic strength.
Keywords: bacterial cellulose, nanocrystal, hydrolysis,
*email: tutikdw@ugm.ac.id
adsorption, ionic strength
Synthesis of N-hydrogen pyrazoline and its cytotoxicity
test towards cancer cells have been carried out, starting 1124- Phytochemical Analysis and
from materials 2,4-dihydroxy acetophenone and p-
anisaldehyde and catalyst KOH 40%. Chalcone has been
Cytotoxicity of Fruit Extracts Sausage
synthesized from those starting materials with (Kigelia Africana) Against Breast
sonochemistry method in 7 hours. Cyclocondesation
reaction of chalcone with hydrazine monohydrate gave N-
Cancer Cells (Mcf-7) in Vitro
hydrogen pyrazoline with sonochemistry method in 2.5
hours. Then, those products were characterized by TLC, Dwi Fitri Yani, Purwantiningsih Sugita, Gustini Syahbirin
TLC-scanner, direct inlet MS, FT-IR, 1H- and 13C-NMR.
Cytotoxicity assay of N-hydrogen pyrazoline was carried Department of Chemistry, Bogor Agricultural University
out by MTT method towards WiDr, MCF-7, T47D, and
HeLa cell lines. Synthesis of chalcone produced bright This study aimed to determine phytoconstituent, active
yellow solid in 45.53% yield with 86.45% purity and a compound of fruit extract of K. africana and evaluate its
melting point of 177.5-180.5 oC. N-hydrogen pyrazoline cytotoxicity on breast cancer cells (MCF-7) under in vitro
was obtained as brown white solid with yield 95.74% and conditions, which Indonesia has a serious problem in term
purity 95.05%. From the cytotoxicity test of the product, it of breast cancer. Fruits of K. africana were extracted with
was shown that the IC50 of N-hydrogen pyrazoline against methanol by maceration method. Separation and
WiDr, T47D, HeLa, and MCF-7 was 42.99; 66.06; 51.55 and purification were done by column and thin layer
74.05 µg/mL. It was concluded that N-hydrogen pyrazoline chromatography preparative method. Identification of the
has medium toxicity against WiDr, T47D, HeLa and MCF-7 isolated compound was analyzed by using liquid
cells and inhibits cancer cell’s proliferation effectively. chromatography-mass spectrometry (LC-MS). Inhibition of
proliferation of breast cancer cells (MCF-7) was tested for
Keywords: Chalcone, N-hydrogen pyrazoline, p- the purified fraction using 3-(4,5-dimethyl thiazole-2-yl)-2,
anisaldehyde, sonochemistry, cytotoxicity assay 5-diphenyltetrazolium bromide (MTT) assay. The result
phytoconstituents such as terpenoids, flavonoids,
alkaloids, and phenolics were present in the K. africana
1122- Preparation of Bacterial extract. Purification of fruit extract of K. africana resulted
Cellulose Nanocrystals for Protein three fractions and indicated strong activity in inhibiting
the proliferation of breast cancer cells (MCF-7) with IC50
Adsorption value of 1.89; 1 x 10-2 and 3.2 x 10 -7 μg/mL for A, B2 and
C fractions, respectively. Identification of B2 resulted
Bambang Piluharto*, Ardi Budianto, Dwi Indarti predominant phenolic compounds ie 5,7-dimethoxy-4-
methyl coumarin (1), and 3',6-dimethyl flavone (2).
Department Chemistry, University of Jember
Keywords: Kigelia africana, phenolic compounds, 5,7-
Bacterial cellulose Nano-crystal (BCN) uses as protein dimethoxy-4-methyl coumarin, 3',6-dimethyl flavone, MTT
adsorbent due to its advance properties such as high assay, breast cancer cells MCF-7
surface area, high crystallinity, and dispersible well in
39
1125- Studi Efektivitas Lignin sebagai 1126- Development of Nanoporous
Pengkelat Logam Pengotor Hasil Carbon Paste/Imprinted Zeolite
Leaching Bertahap dari Terak Timah Electrode as Potentiometric Sensor
Ii untuk Meningkatkan Kadar Logam for Creatinine Analysis
Nb dan Ta
Miratul Khasanah, Muji Harsini, Usreg Sri Handajani, Alfa
* Akustia Widati, Putri Agnes Nyla Chandra
Randy Chandra , Agustino Zulys.
Chemistry Department, Science and Technologi Faculty,
Departmen Kimia, Fakultas Matematika dan Ilmu
Universitas Airlangga
Pengetahuan Alam, Universitas Indonesia, Depok 16424,
Kampus C, Jl. Ir. Soekarno, Surabaya 60115
Indonesia
corresponding author:miratulkhasanah@fst.unair.ac.id
*email: randy.chandra@ui.ac.id
Nanoporous carbon paste electrode modified imprinted
XRF characterization of tin slag II contains tantalum oxide,
zeolite has been developed as a sensor to analyze
niobium oxide, quartz, calcium oxide, rutile, aluminum
creatinine by potentiometry. Imprinted zeolite (IZ) was
oxide, hematite, and zirconium oxide. Tin slag II has Nb2O5
synthesized by mixing tetraethyl orthosilicate (TEOS),
and Ta2O5 which contains of 0.64% and 0.33% mass. In this
tetrabutyl orthotitanate (TBOT), tetrapropylammonium
research, a study of increased levels of Nb5+ and Ta5+ ions
hydroxide (TPAH), and water with a mole ratio of
from tin slag II using gradual leaching and chelating
1:0.017:0.24:21.1. Amount of creatinine was added to the
agents. After leaching 100,0370 grams of tin slag II for four
mixture up to the mole ratio of creatinine/Si was 0.306.
hours at 250°C using 194 mL NaOH 6 M, then adding 100
Then creatinine was extracted from zeolite structure to
hydrochloric acid 3.25 M and waiting for 15 minutes at
form a specific imprinted for creatinine. The synthesized
50°C - 70°C, the result obtained was 54.46 gram of the
zeolite was characterized using x-ray diffraction (XRD) and
remaining tin slag II. The result of leaching I was added
fourier transform infrared spectrophotometer.
100 ml HF with concentration variation, green solution
Nanoporous carbon paste/IZ electrode was prepared by
was produced. The best measurements of ICP-OES
mixing nanoporous carbon, IZ, and paraffin with ratio of
resulted in the rest of the metal compositions of PLS 5.
45:20:35 by mass. The research showed the optimum pH
Lignin plays a role in bonding with metals, which has been
of creatinine was 6–7, the measurement range was 10-3–
characterized by FT-IR obtained at 750 nm peak. Final
10-7 M and the Nernst factor was 31.1 mV/decade. Limit of
measurements with MP-AES after the addition of ligands
detection of the potentiometry method to analyze
with volume comparison 4:1 to PLS 5 obtained the best
creatinine was 1.05x10-7 M. The presence of urea in the
resultt to increase the concentration of Nb and Ta. The
solution did not interfere to analysis of creatinine. The
decrease in Nb content was only 37.06%, while for Ta
accuracy and precision level of the method were 88–109%
increased the rate of 103.54%. For Ca, Fe, and Al has
and 97.44–99.04%, respectively. The developed electrode
decreased significantly, that is 67,34%, 82,51%, and
showed response time of 135–150 s and the life time of 6
66,62%. Lignin plays a significant role in increasing levels
weeks.
of Nb and Ta.
Keywords: creatinine, imprinted zeolite, potentiometry,
nanoporous carbon electrode
40
1127- Properties of Mercury 1128- Low Cost Production of Hard
Reductase Enzyme from Local Shell Capsules from Seaweed-Starch
Bacillus Sp. for Bioremediation Agent
Pratiwi Pudjistuti1, Siti Wafiroh1 dan Esti Hendradi2
1* 1
Purkan Purkan , Yuliana Firdausi Nuzulla , and Sofijan 1
Departemen Kimia, Fakultas Sains dan Teknologi,
Hadi1
Universitas Airlangga, Surabaya
2
Departemen Farmasetika. Fakultas Farmasi, Universitas
Department of Chemistry, Faculty of Science and
Airlangga, Surabaya
Technology, Airlangga University
Corresposding author: purkan@fst.unair.ac.id
*email: tiwi2000@hotmail.com
This research was expected to help provide solution to
Production of hard shell capsules from seaweed extract is
environmental problems cause by enviromental pollution, a new innovation to substitute gelatin hard shell capsules.
especially mercury around industries that use mercury. The specification of seaweed-starch 0-size of hard shell
Enzyme mercury reductase is the important enzyme as capsules were determined, such as length, thickness,
mercury bioremediation agent. This research aim to the weight, moisture content and disintegration time in
determinate resistance level of a local Bacillus isolates sp comparation with gelatin hard shell capsules. The number
of hard shell capsules from seaweed extracts could be
on the media which containing HgCl2, mercury reductase
produced 10,000 pcs/kg a day and the price of a piece of
enzyme activity and characteristics of mercury reductase
hard shell capsule and hard shell capsules combination
enzyme produced. Isolates of bacteria grown on the seaweed extract-starch are Rp. 39.5,-/pcs and Rp 17.5,-
Nutrient Broth media which containing the variety of the /pcs, respectively. The price of seaweed-starch is cheaper
level of HgCl2 to know the response of growth of Bacillus than seaweeds extract. The cost of production hard shell
sp bacteria against mercury which is done using the capsules from seaweeds to seaweed-starch was reduced,
method of Optical Density (OD) at λ 600 nm. Mercury Rp. 4.84 billion/month.
reductase enzyme activity was tested by using a solution
Keywords: hard shell capsules, seaweed-starch, low cost
of MRA (Mercury Reductase Assay) and is determined production
from the oxidation of NADPH by observing a decrease in
absorbance at λ340 nm. The result showed that local
isolate Bacillus sp. able to resist in mercury containing
media by concentration up to 80 µM. Mercury reductase
enzyme produced by Bacillus sp. had optimum growth
1129- Increasing the Production of
time of 16 hours with enzyme activuty of 0,574 Unit/µg. the Extracellular Thermophilic β-
Mercury reductase enzyme has optimumcondition at pH 6 xylosidase by Recombinan Bacillus
and temperature of 37°C.
Megaterium MS941
Keywords: Mercury, Bacillus sp, mercury-resistant (1*) (1)
Hadi S, Nyoman TP, and (2)Ariff, A.B*
bacteria, enzym mercuric reductase, bioremediation
1
Department of Chemistry, Faculty of Science and
Technology,
Airlangga University.Surabaya East Jawa, Indonesia.
2
Department of Bioprocess Technology, Faculty of
Biotechnology and Biomolecular Sciences, Universiti Putra
Malaysia, 43400 UPM Serdang, Selangor, Malaysia
43
molecule and Eg5 protein which means that the complex activity of crude enzyme was 8.191 U / mg, whereas pure
formation occurs spontaneously. Intramolecular α-L-arabinofuranosidase enzyme of purification with Ni-
interaction between target molecule and Eg5 protein NTA has a specific activity of 11.427 U / mg. The α-L-
occurs through hydrogen bond with amino acid residue, arabinofuranosidase showed optimum activity at 70 ° C
Glu116 or Gly117. In vitro anticancer activity was with the stability from 50 to 70 ° C and optimum pH was
determined by MTT assay toward breast cancer cell lines 8, while for pH stability of 4 to 7. α-L-arabinofuranosidase
T47D and cervix cancer cell lines HeLa. DHPM 4 showed extracellular of E. coli BL21 (DE3) / pBM5ABF) that have
the best anticancer activity against T47D cells with IC50 been generated in this study had optimum activity at pH 8
value of 32,105 μg/mL, while for HeLa cell, DHPM 5 and the activity decreased drastically at pH 9. Increasing
showed the best activity with IC50 value of 1,935 μg/mL. its pH was done by directed evolution using PCR-
errorprone. Screening α-L-arabinofuranosidase with MUA
Keywords: Dihydropyrimidinone deratives, Biginelli substrate produces positive variants that emit high-
reaction, anticancer, molecular docking. intensity blue fluorescence at pH 9, the second stage of
screening was then performed with pNPA substrate in
buffer NaOH-glycine at pH 9. The highest activity in
Variant A12 that is equal to 2.874223 U / ml, while for the
activity of the control (wildtype) of 0.754 U / ml. This
1137- onstruction and means that the activity of α-L-arabinofuranosidase
Characterization of α-L- enzyme variant with pNPA substrate in buffer at pH 9
increased 4-fold of the enzyme activity of α-L-
arabinofuranosidase Variant into arabinofuranosidase wildtype.
Escherichia Coli Extracellular Keywords: α-L-arabinofuranosidase variant, M5 plasmid
Secretion System system, directed evolution.
Keywords: isoflavones, Friedel-Craft acylation, cyclization Keywords: Extra Virgin Coconut Oil, black cumin oil,
antioxidants, induction period
of deoxybenzoin
46
1150- The Efficacy of Methanol 1152- Effect of Calcination Time, OH /
Extract of Morinda Citrofolia to Brain Al ratio, and Keggin / g Suspension on
Derived Neurotrophic Factor (BDNF) Natural Bentonite
and Spatial Memory Ability on Male
Ady Mara Rachman*
Swiss Webster Mice Induced by
Immobilization Stress Department of Chemistry, Universitas Sriwijaya
*email: mararachman@gmail.com
Eka Febri Zulissetiana, Susilawati
Natural Bentonite activation has been carried out from
Medical Faculty of Sriwijaya University
klaten. Activation was carried out by refluxing natural
*email: susilwt78@gmail.com
Bentonite using 2M sulfuric acid, then variation of
calcination time, OH / Al ratio and suspension of keegin / g
Aging process is associated with declines in certain
Bentonite. Calcination is done by using microwave oven
cognitive abilities such as learning and memory ability and
2.45 GHz. Determination of acidity is done by calculating
impact on high risk of dementia, physical disability and
the amount of ammonia and pyridine adsorbed, while
death. Oxidative stress is believed as basic mechanism of
porosity is done with SAA. Characterization of functional
aging process. Morinda citrofolia (Noni fruit) has long
groups, crystallinity and morphology were analyzed using
been used as a traditional plant in worldwide and was
FTIR, XRD, SEM, and TEM. It has been found that Al-pillar
proven empirically in traditional medicine as antioxidant.
bentonite catalyst was successfully prepared using a
The purpose of this study was to evaluate neurotrophic
microwave oven. The calcination time, the OH / Al ratio
effect of Morinda citrofolia extract on Male Swiss Webster
and the higher suspension concentration tend to increase
Mice Induced by Immobilization Stress. This research is
the acidity of bentonite, as well as the surface area, while
experimental study with post test only control group
the pore diameter, pore volume decreases. The
design. Male Swiss Webster Mice were induced by
optimization occurred at the concentration of 2 M sulfuric
immobilization stress and ramdomized into seven groups
acid and the calcination time of 20 min, the Keegin ratio of
(5 mice/groups). The first group was negative control
2.2 OH / Al and the suspension of 10 mmol / g with
group; Group 2,3,4,5 and 6 was given treatment with
adsorption of 11.76 mmol ammonia / gram and 2.44
varied concentrations of Morinda citrofolia (50, 100, 200,
mmol pyridine / gram, pore volume 0.13 cm³ / G, pore
400 and 800 mg/kgBW). Vitamin E (70 mg/kgBW),
diameter 3.38 nm and surface area 154.64m2 / g. The FTIR
standard antioxidant was used as positive control (Group
spectra show no fundamental structural changes in
7). Brain BDNF level of the white mice were measured by
natural bentonite, the XRD pattern slightly shifts to the
using ELISA method, while the spatial memory ability was
top with a lower angle, being due to the pillarization, the
assessed by using Morris Water Maze Test. Experiment
SEM and TEM images show an increase in space or plane
result showed that treatment with Morinda citrofolia
extract (50, 100, 200,400 mg/kgBW) and Vitamin E 70
Keywords: Natural Bentonite, Pillarization,
mg/kg BW showed a significant difference in BDNF level
characterization
compare with the negative control rats. There is no
significant differences between 200 mg/kgBW Metanol
Extract of Morinda citrofolia group and vitamin E
(p=0,301;p>0,05).Conclusion : Methanol Extract of
Morinda citrofolia can prevent the decrement of BDNF
level due to stress.
47
1154- Isolasi dan Elusidasi Struktur amount of the oxidizing agent as well as the reaction time.
The reduction of the resulting graphene oxide to the
Senyawa Turunan Terpenoid dari expected graphene was done with two metals, zinc and
Kulit Batang Bintangur (Calophyllum iron. From three different amounts of potassium
permanganate, 6, 8, and 10 grams for each batch, and two
Bicolor) different reaction time, 90 and 120 minutes, the 10-gram
oxidizing agent and 120-minute reaction time gave the
best result. The solubility of the resulting graphene
Dede Sukandar1*, Jamillah Abbas2 dan Nurfitriany
contrasts with that of the graphene oxide and this
Habibah1
property was utilized for the identification of the end
1
Department of Chemistry-Faculty of Science and product. It is found in this work that iron reduce the
Technology UIN Syarif Hidayatullah Jakarta graphene oxide into graphene more effectively than zinc.
2
Pusat Penelitian Kimia – LIPI Kawasan Puspiptek Serpong
Keywords: Hummer method, graphene oxide, graphene
*email: eds_tea@yahoo.co.id
50
1179- Antibacterial Activity of has several utilities in the health field. Chitosan
nanoparticle is modified chitosan in the form of
Endophytic Fungi Isolated from the nanoparticle so that it can dissolve in water and will be
Leaves of Jambu Biji (Psidium more effective to be used in several fields. The objective
of this research is to determine the effectivity of chitosan
guajava L.) and nanoparticle chitosan obtained from crab shells of
rajungan to reduce the in vivo cholesterol total. The
research method was started by isolation chitin from crab
Susilawati*, Ella Amalia
shell powder by several methods such as
Kedokteran Umum Fakultas Kedokteran Universitas demineralization, de-colorization, and deproteinization.
Sriwijaya, Jl. Dr. Muh.Ali Kompleks RSUP Palembang Furthermore, chitin obtained was undergone the
30126, Indonesia acetylation reaction using deacetylase enzyme from
Bacillus licheniformis HSA3-1a for 2 h at a temperature of
*email: elfita_kimia@unsri.ac.id 500C to produce chitosan, and the product was then
characterized. In addition, the chitosan nanoparticle was
Antibacterial resistance has been a major health issue and synthesized through an ionic gelation method. The
still presents threat to health care system globally. particle size was determined by a particle size analyzer
Endophytic fungi, particularly those isolated from (PSA). Results showed that the produced chitosan had
medicinal plants for their potential as source of new characteristics as follows: water content was 5.47%, ash
antibiotics. Endophytic fungi were isolated from the level was 1.55%, N-total was 6.78% and the degree of
surface sterilized leaves of jambu biji (Psidium guajava L.) acetylation was 78.4% with the powder color of white
using potato dextrose agar (PDA) and the isolates were yellowish. Based on the PSA analysis, the particle sizes of
identified through their morphological characteristics. The chitosans were 224.68 and 204.32 nm for NpC 0.1% and
antibacterial activities from ethyl acetate extracts of NpC 0.2% with the polydispertion index of 0.226 and
endophytic fungi were evaluated against Escherichia coli 0.261 (pdi<0.5), respectively. This indicated that particle
and Salmonella tiphi by Kirby Bauer method. Four sizes of the products were uniform. The effectivity test
endophytic fungi were isolated from leaves of jambu biji result of chitosan to reduce in vivo cholesterol using white
and identified as Aspergillus niger Van Tieghem, rats (Rattus norvegicus) showed that the reduction value
Aspergillus flavus, Aspergillus fumigatus Fres, and of cholesterol was 1.87% and 2.14% for chitosan and
Aspergillus sp.(DJb4). The antibacterial activity of the nanoparticle chitosan, respectively at the cholesterol and
extracts is classified as moderate and strong catagory nanoparticle cholesterol concentrations of 10 mg for the
because it has inhibition zone in the range of 50-75% time duration of 14 days.
compared to standard antibiotics. Thus this extract has
the potential to be developed into an antibiotic drug. Keywords: Crabs; B. licheniformis; chitosan; chitosan
nanoparticles; cholesterol
Keywords: antibacterial activity, endophytic fungi, jambu
biji (Psidium guajava L.)
*email: chemadi.ku@gmail.com
52
1193- Production Biomethane from functional groups contained in liquid medium during arc
discharge process. The arc discharge method was
Palm Oil Mill Effluent (POME) with performed using graphite electrodes and liquid medium
Trucated Pyramid Digester in Fed consisted of ethanol 50% with the various addition of
acetic acid, urea and ethylenediamine. Analysis of TiO2-
Batch System carbon nanocomposite characters using XRD, TEM, SEM,
FTIR and UV reflectance. Diffractogram pattern of all
nanocomposites showed peaks at 25.32˚; 26.61˚; and
Martha Aznury1*, Jaksen M. Amin1, Abu Hasan1, Arin Putri 36.14˚ which are the main characteristic peaks of TiO2, C
Dila 1 graphite, and titanium carbide. TEM analysis found that
1
Department of Chemical Engineering, Politeknik Negeri size of nanoparticles was in ten nanometers. SEM analysis
Sriwijaya, Palembang showed the structure of the nanocomposite had a
Jl. Srijaya Negara Bukit Besar,Palembang 30139, Indonesia spherical structure. Analysis using UV reflectance
spectroscopy the bandgap energy of TiO2/C was narrower
*Email : martha_aznury@polsri.ac.id than the bandgap energy of TiO2. The successful surface
modification of TiO2/C was indicated by better dispersion
Palm oil mill effluent (POME) production in Indonesia is of nanocomposite in water and ethanol compared with
estimated around 63 million ton/year [1]. Therefore it is those prepared in ethanol only. Surface analysis using
a potential source of contamination when it directly Fourier transform infrared spectroscopy (FTIR) showed
discharged into river. Even though, POME will be as raw fabricated nanoparticles of TiO2/C in ethanol with addition
resource biogas production.The aims of this research acetic acid has the stretching vibration of Ti─O; C─H; C═O;
was to know the effect of fermentation time toward C─O; O─H; C═C in region of 450-550 cm-1; 2900-2880 cm-
biogas production in pyramid digester. The study was 1; 1690-1760 cm-1; 1050-1300 cm-1; 3400-3700 cm-1;
done in three combinations of feedstock with POME and ~1600 cm-1, respectively. Meanwhile, TiO2-carbon
concentrations of 90, 80, and 70% and activated sludge synthesized in liquid media ethanol with addition urea or
concentrations of 10, 20, and 30%. A mixture of POME ethylenediamine revealed C=O, N-H bend, C-N, C-O, and
and activated sludge at 6 L/minutes for 30 days were fed N-H stretching vibration shown at 1600-1700, 1500-1600,
into digester. The result showed the fermentation time 1100-1200, 1200-1300 and 3300-3400 cm-1 respectively.
gave significant effect toward biogas production in the Keywords: arc discharge; surface modification;
pyramid digester. All combinations showed the upward nanocomposite; photocatalyst; TiO2; Carbon
trend in the volume of biogas during fermentation. The
highest quantity of biomethane in biogas was 25% mol
that the active microbes were added to POME in the
ratio 1: 9 in a fed batch bioreactor.
1197- Study Adsorption Ion
Keywords: biomethane, fed batch, palm oil mill effluent
(POME), trucated pyramid digester. Lanthanum and Erbium Using Pectin
from Banana Peel
55
1221- Characterization, Dating 14C 1223- Docking and Molecular
and Composition of Banjar’s Boat Dynamics Evaluation of Cycloartenol
Artifact from Around Candi Laras Anticancer Activity Through ERK2
Site, Barito River-Kalimantan Inhibition
Tanto Budi Susilo1*, Taufiqur Rohman1, Satrio, Amalinsih1 Hawwin Thoriqul Huda1*, Luthfan Irfana1*, Suminar Setiati
Achmadi1
Program Study of Chemistry, Faculty of Mathematics and
Natural Sciences, Lambung Mangkurat University Department of Chemistry, Bogor Agricultural University
*email: tantobsusilo@gmail.com *email: luthfan.irfana@ipb.ac.id
The diaspora of Austronesian was the biggest in the world Cycloartenol-like compound has been reported to have
at prehistoric era. Currently, geopolitics of Indonesian was anticancer activity by inhibiting the proliferation of Hep
a part of territory of Austronesian that called a nation of G2 liver cancer cell lines. This study aims to evaluate this
seafaring or riverman. In South of Kalimantan, there are activity by computational approach. Steroids, like
12 sites of human settlement along of the Barito river, cinobufagin, are known to be active against liver cancer
including the site where the discovery Banjar’s boat cells by decreasing miR-494 expression. Cycloartenol rigid
(jukung sudur) artifacts was Candi Laras site. This study docking on various proteins which is known to decreases
improved a analysis of artifact archeological based on miR-494 expression showed the best affinity to ERK2
spectroscopy. The FTIR study more changes in chemistry although weaker than SCH772984 affinity. Flexible
of Banjar’s boat. The our data shown that IR spectrum is docking results showed that the cycloartenol may adopt a
not sharp band at 1735 (s) cm-1 as C=O stretching in lignin type I kinase inhibition but requires structural
and hemicelluloses, and at 894 (w) cm-1 as C-H glucose modification to match SCH772984 fit. Molecular dynamics
ring. There were a Fe-O on hematite that confirmed at simulations of cycloartenol-ERK2 complex also showed
532,35 (w) cm-1 band and a progressive decrease in that cycloartenol is still less able to sustain complex
holocellulose that a corresponding decrease in the conformations than cinobufagin and SCH77298.
intensities of lignin, cellulose and hemicelluloses (at Computed pharmacokinetic properties indicates that
2931,80 (s), 1627,92 (s, b), 1512 (w), 1427,32 (w), 1365 cycloartenol has considerable absorption, permeability,
(w), 1265 (w) and 1056,99 (s) cm-1). The dating 14C, the and toxicity properties but the partition coefficient
age of was 2087 year ago and the Banjar’s boat artifact exhibits high lipophilicity that may possibly reduce the
was tangible culture. The XRF data are Mg ;Al ;Si; Fe; Ti; Cu molecular potential as a drug candidate. The
and Zn. Based on result, the suggested that there was computations for cycloartenol derivatives is in progress
Candi Laras site since prehistoric. The our human and will be presented in the full paper.
prehistoric indicated who have been skill as human
seafaring on Barito river. Keywords: in silico; docking; molecular dynamics;
cycloartenol; erk2; liver anticancer; mrna-494
Keywords: FTIR, dating 14C, XRF
56
1225- Silver Deposition on Titanium this work was synthesis of ionic liquids, preparation of
banana stem, and nanocrystalline cellulose isolation. The
Oxide by Using Liquid Impregnation spectroscopy (FTIR and 1H-NM) study results for synthesis
Method of ionic liquids shows that the cis-oleil imidazolinium
acetate ionic liquid in this research was successfully
synthesized. The infrared spectroscopy results of the
Chanel Tri Handoko1*, Adri Huda1, Muhammad Djoni cellulose after treatment shows that the cellulose type is
Bustan1, Bambang Yudono1, Fakhili Gulo1 II, which means the distribution of hydrogen bonding
interactions have regularly seen on O2(O Nr.2)-O6(O Nr.6)
1
Universitas Sriwijaya bond. The X-Ray diffraction study results of cellulose after
treatment shows the peak at 2θ=20.1, that indicates also
*email: fgulo@unsri.ac.id of the nanocrystalline cellulose. The thermogravimetric-
differential thermal analysis (TG-DTA) study results shows
Silver nanoparticle was successfully deposited on TiO2 a decreasing in thermal stability of the cellulose after
surface by using liquid impregnation method. The silver treatment which indicates the increase of surface area
deposition onto TiO2 was conducted by mixing amount of and shows that filtrate cellulose after treatment are nano-
TiO2, AgNO3, and distilled water under 200C for 4 hours sized. The SEM results shows a change in the particles size
followed by calcining at 500C for 3 hours. XRD result of the cellulose after isolation step. The TEM results
reveals that the prepared materials adopt TiO2 anatase indicate the particles size of the cellulose with length ±330
structure. According to the UV-visible spectroscopy nm and diameter ±54 nm in optimum condition at 100W
method, the prepared Ag/TiO2 has an absorption in the for 30 minutes. The study found that the extraction of
visible light region compared to TiO2. The FTIR spectra of cellulose using fatty acid based ionic liquid is a simple,
Ag/TiO2 show an absorption peak at ̴ 380 cm-1 indicating inexpensive, and environmental friendly way for the
an interaction between Ag and TiO2. The morphology and production of nanocellulose.
particle size of the materials studied using SEM show the
porous, agglomerated, and rough morphology of Keywords: Nanocrystalline Cellulose, Banana Stem, Fatty
microparticles. The TEM images reveal the distribution of Acid based Ionic Liquids, and Fatty Imidazolinium
silver nanoparticle with a diameter size of ̴10 nm on the
TiO2 surface.
57
reported that combination between FA and monoketone 1233- Ni-Catalyzed Isomerization of
curcumins showed synergistic activity against α-
glucosidase enzyme. Combination FA and (2E,5E)-2,5- Phenylpropenoids and
bis(4-hydroxy-3-methoxy)benzylidene)cyclopentanone Hydrogenation of Furfural
(AC1) showed highest inhibition activity at the mole ratio
of FA to AC1 2:1 while combination FA to (2E,6E)-2,6- Yessi Permana*
bis(3,4-dimethoxy)benzylidene)cyclohexanone (AC2)
showed the highest inhibition at ratio FA to AC2 1: 3. We Inorganic and Physical Chemistry Research Division,
could not concluded yet which substances gave stronger Institut Teknologi Bandung
role to synergism.
*email: yessi@chem.itb.ac.id
Keywords: Monoketone curcumin; ferulic acid;
antidiabetic; α –Glucosidase; synergism Stereoselective isomerizations of phenylpropenoids (i.e.,
eugenol, methyl eugenol, estragole, and allyl phenol) to
trans-isomerized products in a neat condition were
successfully catalyzed by in situ generated
1231- Eicosenoic Acids Derivatives as Ni(0)phosphine. The complex was prepared in situ from a
Novel Inhibitors for Mycobacterium simple Ni(II) salt, phosphine, Zn powder, and a nitrile with
Ni/phosphine/Zn/nitrile mol ratio as low as 1:2:1:1. The
tuberculosis Protein tyrosine catalytic system employed Ni(II) complex as low as 0.167
mol%. The trans-product was generated in high yield
phosphatase B
when nitrile as low as 1 mol eq. to the Ni complex (5 μL)
was added prior to the reaction, indicating a possible
Lalu Rudyat Telly Savalas* formation of Ni(0)nitrilephosphine complex as an active
catalyst. Elucidations of a nitrile role in such
Department of Chemistry, University of Mataram isomerizations were elaborated using eugenol and methyl
*email: rudyat_telly@yahoo.com eugenol substrates. High phenylpropenoids conversions
(>99%) and high selectivity to trans-products (³95%) were
Mycobacterium tuberculosis Protein tyrosine phosphatase observed within an hour. The isomerization of eugenol
B or PtpB is an attractive target for latent M. tuberculosis was in fact completed in 30 min at room temperature to
prevention. Secretion of PtpB by M. tuberculosis upon give trans-isoeugenol (>97%), with Ni turn over frequency
engulfment of this bacterium by phagosome leads to (TOF) up to 1,116 h-1. The complex was also evaluated in
latent M. tuberculosis state by inhibiting the fusion catalytic transfer hydrogenation of furfural to selectively
between bacteria-containing phagosome with lysosome. generate furfuril alcohol in the absence of hydrogen
The fusion will otherwise kill the bacteria since acidic pressure. It was observed that the in situ generated Ni(0)
environment of lysosome and tenth of it hydrolytic phosphine gave only 21% of the product when it was
enzymes are capable of degrading invading bacteria. employed in the reaction for 5 h at 80 °C in ethanol
Although the exact mechanism by which PtpB inhibits solution. However, higher yield was achieved by a sponge-
phagosome-lysosome fusion is not well understood, the like Ni(0), generated from dealuminated Ni-Al alloy. This
possibility to inhibit PtpB might be a strategy to prevent Ni(0) gave furfuril alcohol yield > 60% when employed in
latent M. tuberculosis infection. In this study, novel of the reaction at 150 °C for 4 h in the presence of formic
PtpB inhibitors of eicosenoic acids derivatives are acid and ethanol as a hydrogen source.
described. At low micromolar concentrations, cis-11- Keywords: Isomerizations; Hydrogenation; Nickel(II)
eicosenoic acid, trans-2-eicosenoic acid and cis-2- phosphine; Phenylpropenoids; Furfural
eicosenoic acid can inhibit PtpB activity by 75.23%, 73.57%
and 62.06%, respectively. This result suggests potential
application of eicosenoic acid derivatives as inhibitor of
PtpB in an attempt to prevent latent M. tuberculosis
infection.
Keywords: Protein tyrosine phosphatase B; eisocenoic
acid derivatives; latent M. tuberculosis infection
58
1235- Antimlaria Assay Activity and
Identification of Marker Compound Keywords: Anting-anting (Acalypha indica, L), herbs,
Extract of Anting-anting Herb Plasmodium falciparum, antimalarial assay,
(Acalypha indica l.) standardization
59
917-Synthesis of Sodium
Carboxymethyl Cellulose (Na-CMC)
poster PRESENTATIONS from Water Hyacinth with Mixed
Solvent Using Succinic Acid as
Crosslinker
911- Synthesis and Characterization
of Molecular Imprinted Polymer for Ida Musfiroh1*
Recognition of Atenolol in Biological
Fluids 1
Departemen Analisis Farmasi dan Kimia Medisinal,
Fakultas Farmasi UNPAD
Aliya Nur Hasanah*, Shendi Suryana, Driyanti Rahayu,
Sandra Megantara, Retna Fauzia, Mutakin
Water hyacinth (Eichhornia crassipes (Mart.) Solms.) is an
Pharmaceutical Analysis And Medicinal Chemistry aquatic weed which has high cellulose content so it could
Department, Faculty Of Pharmacy, Universitas potentially be used as raw material for Na-CMC synthesis.
Padjadjaran, Jl Raya Bandung Sumedang Km 21, This study aimed to determine the characteristics of Na-
Jatinangor, 40611 CMC synthesized by isopropyl alcohol, isobutyl alcohol,
and mixture solvent of isobutyl alcohol-isopropyl alcohol
*email: aliya.n.hasanah@unpad.ac.id (1:4) and characteristics of Na-CMC crosslinked by succinic
acid. This study involved isolating α-cellulose, synthesis of
Atenolol is one of the β-blocker agents as first-line therapy Na-CMC through alkalization and carboxymethylation,
for hypertension. Long term used of atenolol was crosslinking Na-CMC by succinic acid and characterization
reported to increase morbidity and mortality in of Na-CMC based on Pharmacopoeia Indonesia, SNI and
hypertension patients compared to other drugs. β-Blocker JECFA. The results showed that Na-CMC synthesis product
are use for heart dysfunction. However, due to the has met all the requirements. Na-CMC with the best
missused possibility, consumption of this drug is strictly characteristics shown by Na-CMC synthesized by solvent
regulated in a whole world. Drugs with strict regulation mixture. However, Na-CMC crosslinked showed decrease
usually exist in complex matrices such as biological fluids. in degree of substitution (DS), sodium content, water
Regarding that, selective extraction and sensitive holding capacity (WHC), oil holding capacity (OHC), and
analytical method are needed to detect and quantify viscosity.
drugs in such condition. Molecular Imprinted Polymer in
solid phase extraction form can extract and Keywords; Water hyacinth, mixture solvent, Na-CMC,
preconcentrate analyte selectively from the blood. Here, succinic acid
we wish to report on the development of imprinted
polymers using methacrylic acid as receptor monomers.
These compounds have shown an affinity for atenolol in
solution and having a hydrophobic interaction based on
computational approach. The resulting polymers were
capable of selective recovery of >95% of atenolol from
blood and >99% krom urine compared to other drugs that
could exist in the blood.
Keywords; -
60
925- Nickel Slag Coated by Titanium
Dioxide for Degradation of Methylene
Blue 948- Probing of Interaction Mode
Between Cyclic Peptide ADTC3 (Ac-
Destri Muliastri1*, A B Widyartha1,Wasiara1, R. Saputra1, CAD TPC-NH2) with E-Cadherin
Muhammad Nurdin1, L O A N Ramadhan1*
Protein using the Molecular Docking
1
Department of Chemistry, Faculty of Mathematics and Method
Natural Sciences, Universitas Halu Oleo, Kendari 93232 –
Southeast Sulawesi, Indonesia
Parsaoran Siahaan1*, Vivitri Dewi Prasasty2, Atiatul
Manna1, Dwi Hudiyanti1
*email: ramadhan305@gmail.com
1
Departement of Chemistry, Faculty of Science and
The utilization of nickel slag waste coated titanium dioxide
Mathematics, Diponegoro University
(TiO2) as material for organic contaminant degradation 2
Faculty of Biotechnology, Atma Jaya Catholic University of
was carried out. The aim of this study is to influence of
Indonesia
degradation time and nickel slag mass for contaminant
degradation in photolysis and photocatalysis system. TiO2
*email: parsaoran_s@undip.ac.id;
was synthesized by usingsol-gel method. Material
siahaan_parsaoran@yahoo.com
characterizations were performed using X-Ray Diffraction
(XRD), X-Ray Fluorescence (XRF), and Optical Microscope.
The ADTC3 peptide is known to increase the porosity of
XRD Analysis of slag coated TiO2(Slag-TiO2) showed that
the tigh junction (TJ) in the BBB E-cadherin adherent
TiO2 in anatase phase at 2θ = 68.30° (230).XRF analysis
junction (AJ) so that the drug can enter the cells and can
showed that dominant compound in nickel slag was
speed up the treatment of brain diseases (such as
silicon. Furthermore, optical microscope analysis showed
Alzheimer's, Parkinson's, and brain tumors). Although
that surface morphology of nickel slag was porous and
macroscopically in vitro E-cadherin peptide has shown
solid. The result of research reveals that degradation test
increasing TJ porosity, the molecular mechanism of
of methylene blue was conducted in photolysis and
interaction within cells is still not widely studied. The
photocatalysis system for 4 hours irradiation with time
hypothesis of interaction between ADTC3 with E-cadherin
interval for 30 minutes.The percentage degradation of
molecularly the amino acid residues of ADTC3 is thought
photolysis and photocatalysis were 48% and 87.50%,
to interact with amino acid residues of E-cadherin
respectively. Meanwhile, a mass variety of slag used in
receptor to inhibit cadherin-cadherin interactions. In this
methylene blue degradation were 5.46 gram; 7.43 gram,
research has been studied complex interaction of ADTC3
and 9.32 gramfor photolysis and 5.49 gram; 8.02 gram,
with domain EC1 of E-cadherin computationally. The
and 10.02 gram for photocatalysis. Degradation
structure of ADTC3 has been optimized with GROMACS.
percentage was increased along with the increase of
The complex interaction of ADTC3 with domain EC1 of E-
nickel slag mass.
cadherin has been studied using docking method. Analysis
of ADTC3 structure was done with optimization molecular
Keywords; Nickel slag, TiO2, photocatalysis, photolysis, dynamics for 120 ns (120,000 ps), and was selected
methylene blue twenty the most stable structure models. The docking
result of these twenty structure shows that each amino
acid of ADTC3 interacts with different types and amounts
amino acid domain of EC1. The most stable interaction
among the twenty structure which interact with the
preferer EC1 active side is the seventh model. The domain
of EC1 interacted are Asp1, Trp2, Ile4, Lys25, Ser26,
Asn27, and Met92 amino acids with binding energy of -
33.10 kJ.mol-1 and Ki of 1.58 μM at the 79187 ps
conformation. The interaction that occurs is precisely on
the active side of domain EC1, so ADTC3 is potential as a
cadherin inhibitor. The results are reinforced by the
interaction of hydrogen bonds between the amino acid
Trp2(O)...Asp3(NH), Trp2(O)...Ala2(NH), and Lys25(O)...
61
Thr4(HG1) with their distance 2.115 Å, 1.931 Å, and 2.112 963- Synthesis and Characterization
Å respectively.
of Nickel doped Zirconia-pillared
Keywords: ADTC3, domain EC1 of E-cadherin, GROMACS, Bentonite
Docking.
63
Macaranga genus is one of Euphorbiaceae family which
produce phenolic compounds including flavonoid and
stilbenoid which are integrated with terpenoid types.
1004- Antioxidant Activity of Roasted Some species of Macaranga have been reported to show
Ginger Oleoresin (Zingiber the antioxidant and antiplasmodial properties. In this
research, methanol extract of Macaranga beccariana
Officinale) that Occurred Reduction Merr. leaves were investigated for its antioxidant property
Reaction using Roots as Biocatalyst using 1,1-diphenyl-2-picrylhydrazyl (DPPH) method and
antiplasmodial property against Plasmodium falciparum
strain 3D7. This extract displayed both activities with IC50
Tagor M Siregar* values of 124.85 and 1.43 μg/mL, respectively.
Universitas Pelita Harapan
Keywords: Macaranga beccariana Merr., antioxidant,
Ginger (Zingiber officinale) is used worldwide as a cooking antiplasmodial, IC50.
spice, condiment and herbal remedy. The main
component in ginger is oleoresin with gingerol being the
major component. Ginger also contains shogaol that are
formed by dehydration of corresponding gingerols during
storage and thermal processing. Shogaol is a ketone group 1011- Screening and
which has a potential as a substrate for reduction of Characterization of Raw Starch
hydroxyl group. The utilization of natural sources food like
carrot (Daucus carota), potato (Solanum tuberosum) and Degradation Amylase from Bacteria
sweet potato jalar (Ipomoea batatas) as a biocatalyst can
Dondang Hot Spring Kutai
be used for asymmetric reduction of prochiral ketones in
ginger oleoresin. This research was designed to utilize Kartanegara
roots as biocatalyst for reduction of bioactive in roasted
ginger and to determine its antioxidant activity. Peeled
Winni Astuti*, Rahmat Gunawan, Daniel Tarigan,
ginger were roasted directly using charcoal fire for 2, 4, 6,
Muhammad Nur Yasin, M. Taufik Asadullah A. Rida'i
8 and 10 minutes. Roasted gingers were then extracted
using methanol by maceration method for 48 hours to get Department of Chemistry FMIPA UNMUL
roasted ginger oleoresin. Roasted ginger oleoresin with
the best roasted time would be reacted with biocatalyst The objective of this research was to screening bacteria
from various roots. Carrot, potato and sweet potato were that produced raw starch degradation amylase from
chosen as the biocatalyst. It was found that ginger Dondang Muara Jawa Kutai Kartanegara hot spring and
oleoresin 8 minutes gave the best effect if its antioxidant characterize the amylase. bacteria screening was done by
activity with IC50 value 45.573 ± 1.584 mg/L. The LB medium containing raw starch and tested with iodine
optimum reaction result was obtained using biocatalyst solution, protein concentration was determined by
from potato. The antioxidant activity was increased up to Bradford method, amylase activity was determined by
68.975 ± 1.193 %. DNS (Dinitrocalisylic acid) assay. The results showed that
the amylase-producing bacteria degrading raw starch was
Bacillus sp. The bacteria produced an extracellular
Keywords: -
amylase. The amylase had an optimum pH of 6 and
temperature of 50°C. Specific activity of the amylase is
2893.47 U/mg. The amylase has ability to hydrolyze raw
starch of sago, cassava, rice, and corn.
1005- The Antioxidant and
Keywords: amylase, raw starch, Dondang hot spring,
antiplasmodial activities of methanol Bacillus sp.
extract from Macaranga beccariana
Merr. Leaves
65
electrical conductivity of nanocomposite up to two orders
of magnitude, from 9.18 x 10-6 to 1.44 x 10-4 S cm-1,
measured by four-point probe instrument.
1058- Pendugaan Umur Simpan
Keywords: purification, multiwall carbon nanotube, Tepung Biji Durian Lokal (Durio
natural rubber latex, electrical conductivity,
nanocomposite Zibhetinuss L) dengan Metode
Akselerasi Pendekatan Kadar Air
Kritis
1132- Synthesis of Membrane Usreg Sri Handajani*, Cahya Nurrahmi H.A., Miratul
Photocatalytic from Pineapple Khasanah
(Ananas comosus) Leaf Fiber
Chemistry Department, Science and Technology Faculty,
Cellulose Diacetate and TiO2 to
Universitas Airlangga, Surabaya
Degrade Congo Red
Siti Wafiroh1*, Nani Dian Sofiana1
In this research, carbon paste/MIP electrode has been
1
Department of Chemistry, Faculty of Science and developed for creatine analysis potentiometrically.
Technology, Airlangga University, Surabaya 60115, Imprinting technique aims to form a mold in accordance
Indonesia with the active site of creatine in MIP. The developed
electrode was manufactured from a mixture of activated
*email): sitiwafiroh@yahoo.com carbon, paraffin, and MIP with ratio of 11:7:2 parts. The
performance of carbon paste/MIP electrode is indicated
Congo Red is a chemical that has a potential hazard to the by Nernst factor values and measurement linearity of 27.2
health of the human body. One technology that can be mV/decade and 0,9915 respectively at concentration
used to degrade the Congo red is a photocatalytic range 10-6-10-2 M, detection limit was 1.1x10-6 M, accuracy
membrane technology. This study aims to create a 55-125, % and the coefficient variation of 0,27-0,60%.
photocatalytic membrane from pineapple leaf fibers of Electrodes still provide good performance untill 85 times
cellulose diacetate (Ananas comosus) and TiO2 which are usage. Selectivity test on electrode is done by using
applicable to degrade the Congo red. The initial phase is glucose matrix and showed that glucose at low and
cellulose insulation. Furthermore, cellulose is used for the normal concentration in blood did not interfere on
synthesis of cellulose diacetate. Preparation of membrane creatine analysis, but high concentration of glucose
is made by phase inversion method using a mixture of disrupted creatine analysis.
cellulose diacetate, formamide, acetone and TiO2. With
variation equal to 0.25%, 0.5%, 0.75%, 1% (w/v) and Keywords: Carbon Paste Electrode, Creatine, MIP,
variation of solvent evaporation time 20, 25, 30 and 35 Potentiometric.
seconds. Membrane characterization performed includes
the thickness, mechanical properties, the performance
and the morphology. Membrane with optimum
mechanical and performance obtained on the
composition of the membrane with 1% TiO2 with
evaporation time of 30 seconds. The results of membrane
characterization are the optimum thickness of 0.047 mm,
flux 11251.1 L.m-2.day-1 and 95.34% rejection, stress 63.83
(N/cm2), strain 0.03 and Modulus Young 1926.45 (N/cm2)
and the ability to degrade Congo red equal to 83.23%.
69
1146- the Effect of Natural Feed, diffraction (XRD) and Vibrating Sample Magnetometer
(VSM). The results showed that the high of crystallinity
Factory and Oils on the Gurami Fish and magnetic properties of MnFe2O4 were synthesized
Weight (Osphronemus Gouramy Lac.) using 3 M NaOH solution at 900C. The measurement
results using the Transmission Electron Microscope show
that MnFe2O4 has a particle size of 10-30 nm.
Emma Zaidar Nasution*
Keywords: MnFe2O4, NaOH concentration, temperature
Departemen Kimia FMIPA USU
*email: emma3@usu.ac.id
70
55°C, while the composite alumina-activated carbon Rumondang Nasution*
obtained at an initial concentration of 30 mg/L, contact
Departemen Kimia FMIPA-USU
time of 90 minutes and the temperature of 75C. The
ability of activated carbon and alumina-activated carbon *email: moonbulaan@yahoo.com
composite for adsorption methylene blue were 10.7205
mg/g and 14.3662 mg/g, respectively.
Toxicity assay of methanol extract leaves parasite coffee
Keywords: activated carbon, alumina, composite, sol gel (Loranthus ferrugineus Roxb.) have been done using Brine
method, methylene blue Shrimp Lethality Test (BSLT). Coffee parasite leaves
extracted by using methanol and the methanol extract
concentrated by vacuum evaporator. Phytochemical
screening test showed positive of flavonoid and terpenoid
compounds. The toxicity assay by using Brine Shrimp
Lethality Test methods using as 10 fish shrimp larva
Artemia salina Leach used with extract volume of 100 μl.
1166- Cloning and Characterization Extracts of leaves parasite coffee made in with variation of
of A Novel Gene Encoded concentration of 20; 40; 60; 80; and 100 ppm. The toxicity
assay methanol extracts the parasite coffee leaves using
Thioesterase from Domas Hot Spring Brine Shrimp Lethality Test showed that the methanol
extract coffee parasite leaves has LC50 values obtained at
Suharti Suharti* 58.88 ppm and had toxic activity characterized by LC50 <
1.000 μg/mL.
Universitas Pertamina, Jakarta Keywords: Toxicity, methanol extract, leaves parasite
coffee, Brine Shrimp Lethality
*email: suharti.s@universitaspertamina.ac.id
72
1182- Physicochemical, Organoleptic
and Prebiotic Properties of Yoghurt 1183- Adsorption of Cobalt (II) on
Added with Fermented Breadfruit Layered Double Hydroxides (Mg/Al
Flour by Laktobacillus Plantarum and Ca/Al) in Aqueous Medium :
Kinetic and Thermodynamic Aspect
Anna Muawanah, Nurul Amilia
Chemistry Department*, Syarif Hidayatullah Islamic State Neza Rahayu Palapa*, Risfidian Mohadi, Muhammad Said,
University Aldes Lesbani
74
1217- How to Improve Quality of the 1219- Immobilized Chitosan and Its
Coloring Silk using Monascus Dyed application on Fe(III) adsorption in
Derived from Cassava Peel Flour peat water
Fermentation
Widia Purwaningrum1*, Nova Yuliasari1, Ismi Anggraini1
Ika Natalia Mauliza*
Department Chemistry, Universitas Sriwijaya
Textile Chemistry Department, Politeknik STTT Bandung
*email: purwaningrum.widia@yahoo.com
*email: nataliamauliza@gmail.com
Chitosan has been modified into immobilized chitosan
Limitations of textile natural dyes resources, lead the contained chitosan powder, dimethyl acetamide, N-
development of textile dyes production through the methyl pyrrolidone, lithium chloride and polyvinyl
biotechnological process. One of textile natural dyes from chloride. Immobilized chitosan was aimed to increase
biotechnological process well known as Monascus dyes. adsorption capacity than chitosan powder to adsorb Fe
Monascus has been industrialized using rice media, known (III) and its application in peat water. The parameter was
as red yeast rice. Currently alternatives of fermentation concentration variation (5,10,15,20,25 ppm), interaction
medium used to produce textile dyes is cassava peel flour. times (30, 60, 90, 120, 150, 180 minutes), pH variations (3,
Monascus dyes have a distinctive color character and 4, 5, 6, 7, 8) and desorption process with hydrochloric
cannot be used in all types of fibers. In this study, acid, sodium EDTA and water. Measurement of Fe (III)
Monascus dyes from cassava peel flour fermentation was used atomic absorption spectroscopy (AAS). Isotherm
applied to the silk fabric. Modification of appropriate adsorption analysis was based on the Langmuir and
dyeing techniques needs to produce silk fabrics that are Freundlich equation. The result of the research showed
not only colored, but have an adequate fastness. Dyes that the adsorption capacity of immobilized chitosan to Fe
developed through the process of fermentation of cassava (III) in 25 ppm, 120 minutes, pH 3,05 is 7.6029 mg. g-1.
peel flour by Monascus purpureus with 55% moisture While in the same condition, chitosan powder show
content for 14 days. Dyestuffs are then used to dye silk adsorption capacity is 6.6465 mg.g-1. In peat water,
through exhaust dyeing techniques at pH 3, 5, and 7 and immobilized chitosan can reduce Fe (III) 83.51%. Based on
with the addition of electrolytes to produce fabrics with the adsorption analysis, Fe (III) adsorption suitable
the highest color strength. Dyed fabrics were then Freundlich isotherm equation with adsorption capacity
compared to the fabrics dyed by red yeast rice. The result 27.77 mg.g-1 and interactions in adsorption Fe (III)
showed that yield of Monascus cassava peel flour had process was physical adsorption by Van der Walls style.
yield of 6 grams per 1000 gram of cassava flour, while red The characterization of used immobilized chitosan using
yeast rice was 10 grams per 1000 gram of rice. Decrease in SEM-EDS indicated Fe (III) has been contained in
pH of the dyeing process gives a significant influence on immobilized chitosan
the dyeing result using Monascus cassava peel flour and
red yeast rice. The lower the dyeing pH, the color strength
of the fabrics getting higher for both of dyestuffs.
Maximum color strength at pH 3. The addition of
electrolyte to the dye gives a better coloring result in 1230- Characterization of Starch
terms of color strength and color absorption than the
fabric processed without the addition of electrolyte. Color
Breadfruit (Artocarpus Altilis) and
fastness to washing, rubbing, and sweat gives excellent Chitosan Edible Film
results (grades 4-5 scale 1 to 5). This indicates that the
dyed fabrics are sufficient to be used as textile products.
Cut Fatimah Zuhra*
Keywords: cassava peel, dyeing, monascus, silk
Department of Chemistry, Universitas Sumatera Utara
*email: cfatimahuhra@yahoo.com
75
amount of 1: 1; 1: 2; and 1: 3 with a total mixture of 4 g in
100 ml of solution using 1.2 ml glycerol as plasticizer, then
dried in an oven at 45 0C for 48 hours. Retrieved Edible
films that have the following characteristics: tensile 1236- Characterization and Partial
strength value obtained for the edible film 1: 1 = 7.7 MPa Purification of Lipase from Cocos
and Percentage of elongation is 10.06%; 1:2 = 3.2 MPa
and Percentage of elongation values is 14.22 % and 1: 3 = nucifera
2.3 MPa and Percentage of elongation values is 22.32%.
Thick of Edible Film was obtained from 0.12 to 0.15 mm.
Jannatin 'Ardhuha
Edible film surface morphology is less homogeneous. FT-IR
analysis showed that in the edible film occurs physical Department of Physic, University of Mataram
interaction only.
The increasing need of lipase has motivated new
Keywords: Edible Film, Bread Fruit Starch, Chitosan, exploration of lipase sources. Meat of germinating
Glycerol, Characterization coconut has been reported to be a good source for lipase.
In this study, we characterized coconut (Cocos nucifera)
lipase and did partial purification by ammonium sulfate
precipitation. It was revealed that 45-60% ammonium
sulfate fraction gave the highest specific lipase activity. It
1232- The Effect Concentration of was also shown by Native-PAGE that coconut lipase
Lignin Extract Inhibitor from Coconut consists of at least two complex proteins of around 110
kDa and 134 kDa. It was further more identified that the
Fiber Waste to Iron Corrosion Rate two complex protein consists of at least 5 different sub
units whose composition is yet to be determined.
Dina Asnawati* Keywords: lipase; Cocos nucifera; ammonium sulfate
precipitati
Department of Chemistry Faculty of Mathematic and
Natural Sciences University of Mataram
*email: dinaasnawati@gmail.com
76