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By:
Pawan KB Agrawal,
Resident MDGP, Year II, IOM,
30th December 2014, Tuesday.
OUTLINE
• Introduction
• Pathophysiology
• Clinical features
• Diagnosis
• Differentials
• Treatment
• Complications
• Prognosis
• References
30-Dec-14 Pawan KB Agrawal 2
INTRODUCTION
• Prevalence:range from 8 to 27
%
• a 2007 systematic review that
included a total of 6242
patients with acutely painful
joints showed 653 (10 percent)
had septic arthritis1.
Predisposing factors:
Elderly >60 years
Diabetes mellitus
Rheumatoid arthritis
Prosthetic joint
Recent joint surgery
Skin infection, cutaneous ulcers
IV drug abuse, alcoholism
Previous intra-articular injection
30-Dec-14 Pawan KB Agrawal 5
PATHOPHYSIOLOGY
Arthrocentesis
usually purulent with
increased count (50,000 to
150,000 cells/mm3)
The synovial fluid glucose is
often depressed and lactic acid
concentration is elevated.
Arthrocentesis
usually purulent with
increased count (50,000 to
150,000 cells/mm3)
The synovial fluid glucose is
often depressed and lactic acid
concentration is elevated.
Synovial fluid culture
X-ray:
The earliest findings are soft
tissue swelling around the
joint and a widened joint
space from joint effusion.
Displacement of adjacent fat
pads may be present,
especially in infants and
children.
Gout
Pseudogout
Transient synovitis
Rheumatoid arthritis
Viral arthritis
Lyme disease
Principle:
Antibiotics
Joint drainage &
Joint rest.
• If deformity is present,
subsequent osteotomy should
be planned to correct it.