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At the end of the discussion, the students will be able NURSING RESPONSIBILITIES IN EARLY DETECTION OF
to: CANCER
1. Summarize the nursing roles and
opportunities in cancer prevention, detection, STEPS TO REDUCE CANCER RISK
diagnosis and treatment of cancer When teaching individual patients or groups,
2. Enumerates the case finding and early nurses can recommend the following cancer prevention
detection methods of cancer. strategies:
3. Explains the major health problems of client 1. Increase consumption of fresh vegetables
with cancer and its specific nursing diagnosis with (especially those of the cabbage family.)
interventions. 2. Increase fiber intake.
4. Identify the psychosocial implications of 3. Increase intake of Vitamin A.
cancer. 4. Increase intake of foods rich in Vitamin C.
5. Differentiate the modes of treatment for 5. Practice weight control.
cancer and its specific nursing responsibilities. 6. Reduce intake of dietary fat.
6. Discuss the nursing management for oncologic 7. Practice moderation in consumption of salt-cured,
emergencies. smoked and nitrate-cured foods.
8. Stop smoking cigarettes and cigars.
CANCER 9. Reduce alcohol intake.
CANCER affects every age group. 10. Avoid overexposure to sun.
The incidence of cancer is higher in men than in
women and higher in industrialized sectors and RECOMMENDATION FOR EARLY DETECTION OF CANCER
nations
Refers to class of diseases or disorders BREAST CANCER
characterized by the development of abnormal Risk Factors
cells that divide uncontrollably and have the • Menarche before age 11
ability to infiltrate and destroy normal body • Menopause after age 50
tissue • Family history of breast cancer – especially
mother or sister
WARNING SIGNS OF CANCER • History of uterine cancer
• Nulliparity or birth of first child after age 30
C - Change in bowel or bladder habits • History of uterine cancer
A - Sore that does not heal • Link with obesity, diabetes and hypertension
U - Unusual bleeding • Presence of benign breast cyst.
T - Thickening or lump
I - Persistent indigestion Screening
O - Obvious change in warts or mole • Breast Self-Examination
N - Nagging cough or persistenthoarseness • Regular mammograms (screen all middle aged
A - Anemia woman)
L - Loss of appetite
COLORECTAL CANCER
DETECTION AND PREVENTION OF CANCER COLORECTAL means colon and rectum combined
Highest for people older than 85 years of age
PRIMARY PREVENTION High for people with family history of colon
Acquisition of knowledge and skills cancer, polyps adenomatous, of inflammatory
necessary to educate client, community about bowel disease, high fat, high protein (with high
cancer risk. intake of beef), low fiber diet, genital or breast
cancer in women
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Diagnostic Procedure - Lesions that are single, hard, & fixed on
1. Colonoscopy – an insertion of fiber optic scope palpation or associated with cervical
through the rectum for direct visualization of the lymphadenopathy, suggest malignancy.
colon.
2. Digital Rectal Examination SCREENING:
Use of fine or large bore needle biopsy,
PROSTATE CANCER Ultrasound, MRI, CT Scan & Thyroid Scan
Risk Factors
• Increasing age, after age 50 LUNG CANCER
• Having father or brother with prostate cancer Most common from cigarette smoking.
doubles the risk of relatives Genetic, underlying respiratory diseases, COPD,
• A diet high in red meat increase risk TB
• Difficulty and frequent urination, urinary most common symptom is a cough or change in
retention, decreased size and force of the urinary cough
stream Repeated unresolved URTI
• Every man older than 40 should have DRE (
Digital rectal exam ) as part of regular check up Diagnostic Examination:
• The more advanced lesion, it becomes “ stony Chest x – ray - is performed to search for pulmonary
hard “ and fixed density, a solitary peripheral nodule (coin lesion),
atelectasis and infection.
DIAGNOSTIC PROCEDURE
Digital Rectal Examination NURSING PROCESS: THE PATIENT WITH CANCER
Prostate Specific Antigen
I. ASSESSMENT
TESTICULAR CANCER • Regardless of type of cancer treatment or
• Primarily affect young to middle-aged men (20 to prognosis many patients with cancer are
35 years old) susceptible to the following problems and
• Most testicular tumors originate in gonadal cells. complications.
• An important role of the oncology nurse is to
Signs: assess the patient for these problems and
Early sign – firm painless, smooth testicular mass complications
varying in size
Late sign – ureteral obstruction, abdominal mass, 1. Infection
shortness of breath
A. Assess factors that promotes infection:
Screening: Testicular Self-Examination(TSE) · Impaired skin & mucus membrane integrity
· Chemotherapy
CERVICAL CANCER · Radiation Therapy
• Refers to the cancer of the neck of the uterus. · Biologic Response Modifiers
· Malignancy
Assessment: · Malnutrition
Painless vaginal bleeding post-menstrual and · Urinary Catheter, Intravenous Catheter
post-coital · Other Invasive Procedures
Foul-smelling or serosanguinous vaginal · Contaminated Equipment
discharge · Age
Pelvic, lower back, leg or groin pain · Chronic Illness
· Prolonged Hospitalization
Diagnostic Procedure
1. Pap’s Smear B. Monitoring laboratory studies to detect early
changes in WBC count
THYROID CANCER – Leukopenia
– Granulocytopenia
– Neutropenia
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C. Chest x- ray C. Determine diet history, any episodes of anorexia,
changes in appetite, altered taste, nausea, diarrhea,
2. Bleeding situation and foods that aggravate or relieve anorexia and
medication history
A. Assess factors that contribute to bleeding
– Bone marrow suppression from radiation D. Clinical and laboratory data useful in assessing
– Chemotherapy Patient’s nutritional status
– Medications that interfere with
coagulation and platelet functioning o Anthropometrical measurements
B. Common bleeding sites: o Serum protein levels
– Skin and mucous membranes o Serum electrolytes
– Intestinal o Skin response to intradermal
– Genito-Urinary Tract injection
– Respiratory tract o Hemoglobin and hematocrit
– Brain levels
C. Signs of bleeding o Serum Iron Levels
– Gross hemorrhage 6. Pain
– Blood in the stools, urine, sputum, or
vomitus A. Related factors causing pain:
– Oozing at injection sites Underlying disease
– Bruising (ecchymosis) Pressure exerted by tumor
– Petechiae Diagnostic procedures
– Changes in mental status Cancer treatment
B. Assess site of pain, pain perception, pain scales
3. Skin Problems C. Give emphasis not only to physical pain but
Assess predisposing factors and other risk factors psychosocial as well.
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o Grieving is a normal response to fears and The patient undergoing surgery for cancer
anticipated losses that include, loss of heath, requires general peri-operative nursing care with
normal sensations, body image, social specific care related to the patient’s age, organ
interaction, sexuality and intimacy. impairment, nutritional deficits, disease of
o Assess response of patient and family about the coagulation and altered immunity that may
diagnosis and planned treatment. increase the risk.
o Assist in answering inquiries and questions,
identifying resources and support people. Peri-operatively, the nurses asses the patient
o Assist patient and family acquire knowledge to response to the surgery.
cope with the disease process
o Assist patient and family members to Monitor possible complication: Post-Operative
acknowledge and cope with their reactions and teaching about wound care, activity nutrition and
feelings. medications information is given.
Managing and Monitoring Potential Complications
2. RADIATION THERAPY
1. Infection
o Strict asepsis technique Ionizing radiation that is used to:
o Health teaching on how to recognize signs and Interrupt cellular growth
symptoms of infection Cure cancer
o Maintain skin integrity. Used to control malignant disease when tumor
o Monitoring laboratory data. cannot be removed surgically used when local
o Administration of antibiotics as ordered metastasis is present
Used prophylactically to prevent leukemia; infiltration
2. Septic Shock to the brain and spinal cord.
o Assess signs and symptoms of septic shock.
o Neurologic assessment SOURCE OF RADITAION THERAPY
o Fluids and electrolyte status monitoring
o Administration of intravenous fluids, blood External Radiation therapy (Teletherapy)
products, vasopressors, oxygen and broad spectrum -administer through an x-ray
antibiotic as ordered. machine
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BRACHYTHERAPY SAFETY PRECAUTION IN RADIATION THERAPY
- Is commonly used as an effective treatment
for cervical, prostate, breast and skin cancer Assigning to a private room
and can also be used to treat tumors in many Posting notices
other body sites. Dosi meter badge must be worn
- Can be used alone or in combination with Not assigning pregnant staff
other therapy such as surgery EBRT and Prohibit children
chemotherapy Limit visits 30 minutes daily
Maintain 3 feet distance
SIDE EFFECT OF RADIATION THERAPY
AND IT’S RESPONSE
3. CHEMOTHERAPY
1. Skin Reaction - Anti-neoplastic agents that are used in an attempt to
- Erythema, dry/moist desquamation destroy tumor cells by interfering with cellular
- Atrophy telangiectasia, depigmentation
function and reproduction.
- Necrotic or ulcerative lesion
Goal:Cure, Control, Palliation
o Nursing Responsibility: Route:Topical, Oval, IV, IM, Subcutaneous,
Observe for early signs of skin reaction and report Arterial, Intra-cavity, and Intrathecal.
immediately
Keep area dry Special Problem:Extravasation
Was area with water, no soap and pat to dry and
do not rub Contraindication:
Do not apply ointment, powders, lotion on the
area 1. Infection
Do not apply heat, avoid sunshine or cold 2. Recent Surgery
Use soft fabric for clothing 3. Impaired Renal or hepatic functions
DO NOT ERASE MARKING ON THE SKIN 4. Recent Rad. Therapy
5. Pregnancy
2. Infection 6. Bone Marrow Depression
3. Hemorrhage
4. Fatigue (radiation cause exhaustion) 2. CHEMOTHEPEUTIC AGENT
5. Weight loss
6. Stomatitis 1. Alkylating
7. Diarrhea - Busulfan, cabopatin, chlorambucilm,
8. Nausea and Vomiting
asplatin, cyclophosphamide, decabazine,
9. Headache
10. Alopecia hexamathyl, melamine, fosfamde
11. Cystitis nitrogen mustard, theothecin.
12. Social Isolation - Alter DNA structure by misreading DNA
code initiating breaks in DNA molecule,
cross linking DNA strands.
PRINCIPLES OF RADIATION PROTECTION 2. Antimetablikes
- Cytaraine 5-flourfacil (5-FU)
1. Distance
- Maintain a distance of at least 3 feet when Pentatastine
not performing nursing procedure - Interfere with biosynthesis of
2. Time metabolic or nucleic acid necessary
- Limit contact with the patient for 5 minutes for RNA and DNA synthesis.
each time, a total of 30 minutes per shift
3. Shielding
- Use lead shield during contact with client
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3. Plant alkaloids b. Diarrhea
- etoposide, teniposide, vinblastine, c. Constipation
vineristine 2. Integumentary System
a. Pruritus, Urticaria, and systemic signs
- Arrest metaphase by inhibiting
b. Stomatitis
mitotic tubular formation (spindle) c. Alopecia
inhibit DNA and protein synthesis. d. Skin Pigmentation
4. Anti-tumor Antibiotic e. Nail Changes
- Bleomian, doxorubicin,mitomycin 3. Hematopoetic System
- Interfere with DNA synthesis by a. Anemia
binding to DNA, prevent RNA b. Neutropenia
c. Thrombocytopenia
synthesis
4. Genito – Urinary System
Vesicant – are those agent if deposited into the a. Hemorrhagic changes
b. Urine color changes
subcutaneous tissues can cause extravasation
5. Reproductive System
Dactoinomycin
a. Premature menopause or amenorrhea
Paunorubicin
Doxorubicin SAFETY PRECAUTIONS IN ADMINISTERING
Nitrogen mustard CHEMOTHERAPY
Mitomycin
*Use of biologic safety cabinet for the
Vinblastine
preparation of all chemotherapeutic agents
Vincristine
*Wear surgical gloves when handling anti-
INDICATION OF EXTRAVASATION DURING
neoplastic agent and the excretions of patients
ADMINISTRATON OF VESICANTS
who received chemotherapy
Absence of blood return from the intravenous
*Wear disposable long sleeved gown when
catheter
prepares and administering chemotherapeutic
Resistance to flow of the intravenous fluid
agents
Swelling, pain, and redness at the site
*Use Leur lock fitting in all intravenous tubing
Of the extravasation is suspected:
used to deliver chemotherapy
Medication administration must be stopped
*Disposable of all equipment used in
immediately
chemotherapy preparation and administration in
Ice applied on the site (expect for vesicant)
appropriate, leak – proof, puncture proof
vinca alkaloid
container.
Physician may aspirate any infiltrate
medication from the tissue and infect
*Dispose of all chemotherapeutic waste as
neutralizing solution onto the area reduce to
hazardous material.
reduce tissue damage
4. THERMAL THERAPY or HYPERTHERMIA
Example of neutralizing solution: Sodium
The generation of temperatures greater
thiosulfate, Nyaluronidase, and Sodium
than physiologic fever range ( above 41.5 ‘C ) has
Bicarbonate
been used for many years to destroy tumors in
human cancer.
SIDE EFFECT OF CHEMOTHERAPY
Using radio waves can produce heat,
ultrasound, microwaves, magnetic waves, and
1. Gastrointestinal System
hot water baths, hot wax immersions.
a. Nausea and Vomiting
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• Liver and renal function should be monitor
Principles: • Offer emotional support and educate the client
1. Malignant cells are sensitive to harmful effects of and family regarding the therapy
high temperatures.
2. Malignant cells lack repair mechanisms necessary 8. GENE THERAPY
to repair cell damage by elevated temperature. • A technique for correcting defective genes
3. Most tumor cells lack an adequate blood supply responsible for disease development.
during periods if increased cellular demand such • A gene is inserted into the genome to replace an
as during Hyperthermia. abnormal, disease causing gene.
• Viruses are used as a gene therapy vectors such
Nursing Management: as retrovirus, adenovirus,herpes simplex virus.
o Local skin care
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4. PERICARDIAL EFFUSION & CARDIAC TAMPONADE PSYCHOSOCIAL ASPECTS OF CANCER CARE
When cancer becomes a part of life’s journey it is
INTERVENTIONS: hardwork.
Monitor vital signs and oxygen saturation Providing support for client (your presence as a
frequently. caring person)
Assess for pulsusparadoxus. Providing support for the family
Monitor ECG tracings Promoting positive self-concept
Assess heart and lung sounds. Promoting coping throughout the cancer
Monitor and record intake and output continuum
Elevate the head of patient’s bed.
Minimize patient’s physical activity. A. Diagnosis and treatment (clients received
Reposition and encourage the patient to cough. diagnosis and treatment in different ways)
Provide frequent oral hygiene. B. Survivorship (client who entered successful
As needed, maintain patient IV access, reorient treatment enter an indeterminate period of long
the patient, and provide supportive measures –term survivorship)
and appropriate patient instruction. C. Recurrent disease and progression (most clients
live with the threat or reality of recurrent
5. DIC/CONSUMPTION COAGULOPATHY disease)
D. Terminal illness, “when everything is done that
INTERVENTIONS: can be done, compassion is the only thing that
Measure and document Intake & output brings beauty and meaning to our lives. It is the
Inspect all body orifices & tubes for bleeding irreplaceable gift.
Prevent bleeding
Administer anticoagulant as prescribed.
Administer cryoprecipitated clotting factors if DIC
progress and hemorrhage is the primary problem.
6. SIADH
INTERVENTIONS:
Monitor accurate recording of intake and output.
Initiate fluid restriction and increased sodium
intake as prescribed.
Administer antidiuretic hormone antagonist as
prescribed.
Monitor serum sodium levels.
INTERVENTIONS:
Monitor Intake and Output.
Encourage oral/IV hydration.
Administer diuretics as prescribed.
Administer medications that increase the
excretion of purine as prescribed.
Prepare to administer IV infusion of glucose
and insulin to treat hyperkalemia.
Prepare the client for dialysis if hyperkalemia
and hyperuricemia persist despite treatment.
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