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NURSING MANAGEMENT OF CLIENTS WITH  SECONDARY PREVENTION

DISTURBANCES IN CELLULAR FUNCTIONING Cancer screening programs for


individuals who are found to be at high risk for
LEARNING OBJECTIVES: cancer

At the end of the discussion, the students will be able NURSING RESPONSIBILITIES IN EARLY DETECTION OF
to: CANCER
1. Summarize the nursing roles and
opportunities in cancer prevention, detection, STEPS TO REDUCE CANCER RISK
diagnosis and treatment of cancer When teaching individual patients or groups,
2. Enumerates the case finding and early nurses can recommend the following cancer prevention
detection methods of cancer. strategies:
3. Explains the major health problems of client 1. Increase consumption of fresh vegetables
with cancer and its specific nursing diagnosis with (especially those of the cabbage family.)
interventions. 2. Increase fiber intake.
4. Identify the psychosocial implications of 3. Increase intake of Vitamin A.
cancer. 4. Increase intake of foods rich in Vitamin C.
5. Differentiate the modes of treatment for 5. Practice weight control.
cancer and its specific nursing responsibilities. 6. Reduce intake of dietary fat.
6. Discuss the nursing management for oncologic 7. Practice moderation in consumption of salt-cured,
emergencies. smoked and nitrate-cured foods.
8. Stop smoking cigarettes and cigars.
CANCER 9. Reduce alcohol intake.
 CANCER affects every age group. 10. Avoid overexposure to sun.
 The incidence of cancer is higher in men than in
women and higher in industrialized sectors and RECOMMENDATION FOR EARLY DETECTION OF CANCER
nations
 Refers to class of diseases or disorders BREAST CANCER
characterized by the development of abnormal Risk Factors
cells that divide uncontrollably and have the • Menarche before age 11
ability to infiltrate and destroy normal body • Menopause after age 50
tissue • Family history of breast cancer – especially
mother or sister
WARNING SIGNS OF CANCER • History of uterine cancer
• Nulliparity or birth of first child after age 30
C - Change in bowel or bladder habits • History of uterine cancer
A - Sore that does not heal • Link with obesity, diabetes and hypertension
U - Unusual bleeding • Presence of benign breast cyst.
T - Thickening or lump
I - Persistent indigestion Screening
O - Obvious change in warts or mole • Breast Self-Examination
N - Nagging cough or persistenthoarseness • Regular mammograms (screen all middle aged
A - Anemia woman)
L - Loss of appetite
COLORECTAL CANCER
DETECTION AND PREVENTION OF CANCER  COLORECTAL means colon and rectum combined
 Highest for people older than 85 years of age
 PRIMARY PREVENTION  High for people with family history of colon
Acquisition of knowledge and skills cancer, polyps adenomatous, of inflammatory
necessary to educate client, community about bowel disease, high fat, high protein (with high
cancer risk. intake of beef), low fiber diet, genital or breast
cancer in women

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Diagnostic Procedure - Lesions that are single, hard, & fixed on
1. Colonoscopy – an insertion of fiber optic scope palpation or associated with cervical
through the rectum for direct visualization of the lymphadenopathy, suggest malignancy.
colon.
2. Digital Rectal Examination SCREENING:
Use of fine or large bore needle biopsy,
PROSTATE CANCER Ultrasound, MRI, CT Scan & Thyroid Scan
Risk Factors
• Increasing age, after age 50 LUNG CANCER
• Having father or brother with prostate cancer  Most common from cigarette smoking.
doubles the risk of relatives  Genetic, underlying respiratory diseases, COPD,
• A diet high in red meat increase risk TB
• Difficulty and frequent urination, urinary  most common symptom is a cough or change in
retention, decreased size and force of the urinary cough
stream  Repeated unresolved URTI
• Every man older than 40 should have DRE (
Digital rectal exam ) as part of regular check up Diagnostic Examination:
• The more advanced lesion, it becomes “ stony Chest x – ray - is performed to search for pulmonary
hard “ and fixed density, a solitary peripheral nodule (coin lesion),
atelectasis and infection.
DIAGNOSTIC PROCEDURE
 Digital Rectal Examination NURSING PROCESS: THE PATIENT WITH CANCER
 Prostate Specific Antigen
I. ASSESSMENT
TESTICULAR CANCER • Regardless of type of cancer treatment or
• Primarily affect young to middle-aged men (20 to prognosis many patients with cancer are
35 years old) susceptible to the following problems and
• Most testicular tumors originate in gonadal cells. complications.
• An important role of the oncology nurse is to
Signs: assess the patient for these problems and
 Early sign – firm painless, smooth testicular mass complications
varying in size
 Late sign – ureteral obstruction, abdominal mass, 1. Infection
shortness of breath
A. Assess factors that promotes infection:
Screening: Testicular Self-Examination(TSE)  · Impaired skin & mucus membrane integrity
 · Chemotherapy
CERVICAL CANCER  · Radiation Therapy
• Refers to the cancer of the neck of the uterus.  · Biologic Response Modifiers
 · Malignancy
Assessment:  · Malnutrition
 Painless vaginal bleeding post-menstrual and  · Urinary Catheter, Intravenous Catheter
post-coital  · Other Invasive Procedures
 Foul-smelling or serosanguinous vaginal  · Contaminated Equipment
discharge  · Age
 Pelvic, lower back, leg or groin pain  · Chronic Illness
 · Prolonged Hospitalization
Diagnostic Procedure
1. Pap’s Smear B. Monitoring laboratory studies to detect early
changes in WBC count
THYROID CANCER – Leukopenia
– Granulocytopenia
– Neutropenia
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C. Chest x- ray C. Determine diet history, any episodes of anorexia,
changes in appetite, altered taste, nausea, diarrhea,
2. Bleeding situation and foods that aggravate or relieve anorexia and
medication history
A. Assess factors that contribute to bleeding
– Bone marrow suppression from radiation D. Clinical and laboratory data useful in assessing
– Chemotherapy Patient’s nutritional status
– Medications that interfere with
coagulation and platelet functioning o Anthropometrical measurements
B. Common bleeding sites: o Serum protein levels
– Skin and mucous membranes o Serum electrolytes
– Intestinal o Skin response to intradermal
– Genito-Urinary Tract injection
– Respiratory tract o Hemoglobin and hematocrit
– Brain levels
C. Signs of bleeding o Serum Iron Levels
– Gross hemorrhage 6. Pain
– Blood in the stools, urine, sputum, or
vomitus A. Related factors causing pain:
– Oozing at injection sites  Underlying disease
– Bruising (ecchymosis)  Pressure exerted by tumor
– Petechiae  Diagnostic procedures
– Changes in mental status  Cancer treatment
B. Assess site of pain, pain perception, pain scales
3. Skin Problems C. Give emphasis not only to physical pain but
Assess predisposing factors and other risk factors psychosocial as well.

4. Hair Loss 7. Fatigue


Assess also the psychological impact of this side  Fatigue has been recognized as one of the
effect on the patient and the family significant and frequent symptoms experienced
by patients receiving cancer therapy.
5. Nutritional Concerns  Assess for feelings of weariness, weakness, lack
of energy, inability to carry out ADL, lack of
COMMON NUTRITIONAL PROBLEMS motivation, and inability to concentrate
1. Anorexia  Assess for physiologic and psychological stressors
2. Mal-absorption that contribute to fatigue, (pain, nausea,
3. Cachexia constipation, fear, anxiety)

A. Impaired nutritional status may contribute to: 8. Psychosocial Status


 Disease progression
 Immune incompetence 9. Body Image and Self-Esteem
 Increased incidence of infection
 Delayed tissue repair II. Nursing Diagnosis
 Diminished functional ability • Risk for infection related to altered immunologic
 Decreased capacity to continue response
chemotherapy • Impaired skin integrity: erythematous and wet
desquamation reaction to radiation therapy.
B.Physical signs of weight loss and cachexia are secondary • Impaired oral mucous membranes related to
to decreased protein and caloric intake, metabolic, stomatitis.
mechanical effects of cancer and systemic disease, side • Imbalanced nutrition: less than body
effects of the treatment or emotional status of the requirements related to nausea and vomiting.
patient.
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• Fluid and electrolyte imbalance related to Assisting Patients to cope with Alopecia:
anorexia, nausea & vomiting, altered taste, o Provide information about hair loss, support
diarrhea patient and family in coping with disturbing
• Anticipatory grieving related to loss of body parts effects of therapy.
and altered role functioning o Instruct to acquire a wig or hairpiece before hair
• Disturbed body image and situational low self- loss.
esteem related to changes in appearance, o Encourage use of attractive scarves and hats.
function and roles
• Self – care deficit due to fatigue, malaise, and Managing Malignant Skin Lesion:
protective isolation o Carefully assessing and cleansing the skin.
• Anxiety due to knowledge deficit and uncertain o Reducing superficial bacteria.
future o Controlling the bleeding.
• Disturbed body image r/t changes in appearance, o Reducing odor.
function and roles o Protecting the skin from pain and further trauma.
• Grieving r/t anticipatory loss and altered role
functioning Promoting Nutrition:
• Potential for spiritual distress o Prepare foods that are appealing.
• Deficient knowledge about disease process, o Patient’s preferences as well as physiologic and
treatment, complication management, and self- metabolic requirements are considered when
care measures selecting foods.
o Encouraged small frequent feedings.
III. Planning o Inform patient the advantage of receiving
o Maintenance of tissue integrity alternative methods of feeding by parenteral or
o Maintenance of nutrition enteral route.
o Relief of pain
o Relief of fatigue Relieving Pain:
o Improve body image o Provide adequate rest and sleep
o Effective progression through grieving o Promote diversional activities
process o Provide adequate rest and sleep
o Absence of complications o Offer Empathy
o Give pain reliever medications as ordered
Nursing Interventions
Decreasing Fatigue
Managing Stomatitis o Help the patient and the family to understand
o Provide good oral hygiene. that is an expected and temporary side effect of
o Use soft bristled toothbrushes and nonabrasive cancer process and of many treatments used.
toothpaste. o Help patient identify sources of fatigue
o Oral swabs with sponge like applicators maybe o Plan activities to conserve energy as well as
use in place of toothbrush. alternate periods of rest.
o Avoid alcohol based mouth rinses. o Regular, light exercise is recommended
o Lubricate cracked and dry lips
o Adequate food and fluid intake is encouraged Body Image and Self-Esteem
o Positive approach is necessary
Maintaining Tissue Integrity o Encourage independence and continued
o Handle affected area gently. participation in self-care decision making
o Avoid rubbing or use of hot or cold water, soaps, o Patient should be assisted to assume tasks and
powder, lotion and cosmetics avoided participate in those activities that are personally
o Avoid tissue injury by wearing loose-fitting of most value.
clothing. o Identify any negative feeling that that the patient
o Aseptic technique should be observed during has or threats to body image.
dressing and wound care. o Referral to support groups
Assisting in the Grieving process

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o Grieving is a normal response to fears and The patient undergoing surgery for cancer
anticipated losses that include, loss of heath, requires general peri-operative nursing care with
normal sensations, body image, social specific care related to the patient’s age, organ
interaction, sexuality and intimacy. impairment, nutritional deficits, disease of
o Assess response of patient and family about the coagulation and altered immunity that may
diagnosis and planned treatment. increase the risk.
o Assist in answering inquiries and questions,
identifying resources and support people.  Peri-operatively, the nurses asses the patient
o Assist patient and family acquire knowledge to response to the surgery.
cope with the disease process
o Assist patient and family members to  Monitor possible complication: Post-Operative
acknowledge and cope with their reactions and teaching about wound care, activity nutrition and
feelings. medications information is given.
Managing and Monitoring Potential Complications
2. RADIATION THERAPY
1. Infection
o Strict asepsis technique Ionizing radiation that is used to:
o Health teaching on how to recognize signs and  Interrupt cellular growth
symptoms of infection  Cure cancer
o Maintain skin integrity.  Used to control malignant disease when tumor
o Monitoring laboratory data. cannot be removed surgically used when local
o Administration of antibiotics as ordered metastasis is present
 Used prophylactically to prevent leukemia; infiltration
2. Septic Shock to the brain and spinal cord.
o Assess signs and symptoms of septic shock.
o Neurologic assessment SOURCE OF RADITAION THERAPY
o Fluids and electrolyte status monitoring
o Administration of intravenous fluids, blood  External Radiation therapy (Teletherapy)
products, vasopressors, oxygen and broad spectrum -administer through an x-ray
antibiotic as ordered. machine

3. Bleeding and Hemorrhage  Internal Radiation Therapy


o Monitor laboratory values especially platelet -administer near or within the
count tumor
o Assess the patient for bleeding
o Taking steps to prevent trauma and minimize the Types:
risk for bleeding  Sealed Source (Brachytherapy )
 Unsealed
PROMOTING HOME AND COMMUNITY BASED CARE
BRACHYTHERAPY
1. Teaching Patients Self-Care - From the greek word “bradys” means, “short
2. Continuing Care - distance”
- Also known as internal radiotherapy, sealed
NURSING MANAGEMENT DIFFERENT source radiotherapy,
MODALITIES OF TREATMENT curietherapyorendocurietherapy is a form of
1. SURGERY radiotherapy where a radiation source is a
place inside or next to the area requiring
Types: treatment.
 Diagnostic
 Prophylactic
 Palliative
 Reconstructive

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BRACHYTHERAPY SAFETY PRECAUTION IN RADIATION THERAPY
- Is commonly used as an effective treatment
for cervical, prostate, breast and skin cancer  Assigning to a private room
and can also be used to treat tumors in many  Posting notices
other body sites.  Dosi meter badge must be worn
- Can be used alone or in combination with  Not assigning pregnant staff
other therapy such as surgery EBRT and  Prohibit children
chemotherapy  Limit visits 30 minutes daily
 Maintain 3 feet distance
SIDE EFFECT OF RADIATION THERAPY
AND IT’S RESPONSE
3. CHEMOTHERAPY
1. Skin Reaction - Anti-neoplastic agents that are used in an attempt to
- Erythema, dry/moist desquamation destroy tumor cells by interfering with cellular
- Atrophy telangiectasia, depigmentation
function and reproduction.
- Necrotic or ulcerative lesion
Goal:Cure, Control, Palliation
o Nursing Responsibility: Route:Topical, Oval, IV, IM, Subcutaneous,
 Observe for early signs of skin reaction and report Arterial, Intra-cavity, and Intrathecal.
immediately
 Keep area dry Special Problem:Extravasation
 Was area with water, no soap and pat to dry and
do not rub Contraindication:
 Do not apply ointment, powders, lotion on the
area 1. Infection
 Do not apply heat, avoid sunshine or cold 2. Recent Surgery
 Use soft fabric for clothing 3. Impaired Renal or hepatic functions
 DO NOT ERASE MARKING ON THE SKIN 4. Recent Rad. Therapy
5. Pregnancy
2. Infection 6. Bone Marrow Depression
3. Hemorrhage
4. Fatigue (radiation cause exhaustion) 2. CHEMOTHEPEUTIC AGENT
5. Weight loss
6. Stomatitis 1. Alkylating
7. Diarrhea - Busulfan, cabopatin, chlorambucilm,
8. Nausea and Vomiting
asplatin, cyclophosphamide, decabazine,
9. Headache
10. Alopecia hexamathyl, melamine, fosfamde
11. Cystitis nitrogen mustard, theothecin.
12. Social Isolation - Alter DNA structure by misreading DNA
code initiating breaks in DNA molecule,
cross linking DNA strands.
PRINCIPLES OF RADIATION PROTECTION 2. Antimetablikes
- Cytaraine 5-flourfacil (5-FU)
1. Distance
- Maintain a distance of at least 3 feet when Pentatastine
not performing nursing procedure - Interfere with biosynthesis of
2. Time metabolic or nucleic acid necessary
- Limit contact with the patient for 5 minutes for RNA and DNA synthesis.
each time, a total of 30 minutes per shift
3. Shielding
- Use lead shield during contact with client
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3. Plant alkaloids b. Diarrhea
- etoposide, teniposide, vinblastine, c. Constipation
vineristine 2. Integumentary System
a. Pruritus, Urticaria, and systemic signs
- Arrest metaphase by inhibiting
b. Stomatitis
mitotic tubular formation (spindle) c. Alopecia
inhibit DNA and protein synthesis. d. Skin Pigmentation
4. Anti-tumor Antibiotic e. Nail Changes
- Bleomian, doxorubicin,mitomycin 3. Hematopoetic System
- Interfere with DNA synthesis by a. Anemia
binding to DNA, prevent RNA b. Neutropenia
c. Thrombocytopenia
synthesis
4. Genito – Urinary System
Vesicant – are those agent if deposited into the a. Hemorrhagic changes
b. Urine color changes
subcutaneous tissues can cause extravasation
5. Reproductive System
 Dactoinomycin
a. Premature menopause or amenorrhea
 Paunorubicin
 Doxorubicin SAFETY PRECAUTIONS IN ADMINISTERING
 Nitrogen mustard CHEMOTHERAPY
 Mitomycin
*Use of biologic safety cabinet for the
 Vinblastine
preparation of all chemotherapeutic agents
 Vincristine
*Wear surgical gloves when handling anti-
INDICATION OF EXTRAVASATION DURING
neoplastic agent and the excretions of patients
ADMINISTRATON OF VESICANTS
who received chemotherapy
 Absence of blood return from the intravenous
*Wear disposable long sleeved gown when
catheter
prepares and administering chemotherapeutic
 Resistance to flow of the intravenous fluid
agents
 Swelling, pain, and redness at the site
*Use Leur lock fitting in all intravenous tubing
Of the extravasation is suspected:
used to deliver chemotherapy
 Medication administration must be stopped
*Disposable of all equipment used in
immediately
chemotherapy preparation and administration in
 Ice applied on the site (expect for vesicant)
appropriate, leak – proof, puncture proof
vinca alkaloid
container.
 Physician may aspirate any infiltrate
medication from the tissue and infect
*Dispose of all chemotherapeutic waste as
neutralizing solution onto the area reduce to
hazardous material.
reduce tissue damage
4. THERMAL THERAPY or HYPERTHERMIA
Example of neutralizing solution: Sodium
The generation of temperatures greater
thiosulfate, Nyaluronidase, and Sodium
than physiologic fever range ( above 41.5 ‘C ) has
Bicarbonate
been used for many years to destroy tumors in
human cancer.
SIDE EFFECT OF CHEMOTHERAPY
Using radio waves can produce heat,
ultrasound, microwaves, magnetic waves, and
1. Gastrointestinal System
hot water baths, hot wax immersions.
a. Nausea and Vomiting

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• Liver and renal function should be monitor
Principles: • Offer emotional support and educate the client
1. Malignant cells are sensitive to harmful effects of and family regarding the therapy
high temperatures.
2. Malignant cells lack repair mechanisms necessary 8. GENE THERAPY
to repair cell damage by elevated temperature. • A technique for correcting defective genes
3. Most tumor cells lack an adequate blood supply responsible for disease development.
during periods if increased cellular demand such • A gene is inserted into the genome to replace an
as during Hyperthermia. abnormal, disease causing gene.
• Viruses are used as a gene therapy vectors such
Nursing Management: as retrovirus, adenovirus,herpes simplex virus.
o Local skin care

5. BIOLOGIC RESPONSE MODIFIERS 9. BONE MARROW TRANSPLANTATION


- is also called IMMNUNOTHERAPY
- Substances that are able to trigger the immune Types
system to indirectly affect tumors. 1. Autologous – from patient
- These include cytokines such as interferons and 2. Allogenic - from a donor other than a
interleukins. patient. Eg.family member, matched
- The basis of BRM is restoration, stimulation, unrelated donor,(bone marrow registry)
modification and augmentation of the body’s 3. Syngeneic - from an identical twin
natural defense against cancer
- E.g. BCG – treat bladder cancer Procedure:
1. Donor suitability is determined through
BRM (Biological Response Modifiers) tissue antigen typing of human leukocyte antigen
Nursing Management: (HLA) and mixed leukocyte culture (MLC)
• Patients receiving BRM therapy have many of 2. Donor bone marrow is aspirated from
the same needs as cancer patients undergoing multiple sites along iliac crest under general
treatment approaches anesthesia
• BRM therapies are still investigational a 3. Donor marrow is infused IV into the
considered a last-chance effort by many patients. recipient
• Essential that the nurse assess the need for
education, support and guidance for the patient COMPLICATIONS:
and family in planning and evaluating patient 1. Failure of engraftment
care. 2. Infection: highest risk in 3 to 4 weeks
3. Pneumonia: non-bacterial or intestinal
6. PHOTODYNAMIC THERAPY pneumonia are principal causes of death on the
- A ternary treatment for cancer involving 3 key first 3 months post-transplant
components: a photosensitizer, light and tissue 4. (GVHD) Graft vs., host disease: principal
oxygen. complication caused by an immunologic reaction
- A photosensitizer is a chemical compound of engrafted lymphoid cells against the tissue of
(Porfimer) that can be excited by a light of a the recipient
specific wavelength. - Acute GHVD – develops within first 100
- Use as a treatment for basal cell carcinoma. days post-transplant and affects
GUT, liver, marrow, and lymphoid tissue
MAJOR SIDE EFFECT: -Chronic GVHD – Develops 100 – 400
days post-transplant manifested by multi-
PHOTOSENSITIVITY FOR 4 TO 6 WEEKS AFTER organ involvement
TREATMENT 5. Recurrent malignancy
6. Late complications such as cataracts, and endocrine
NURSING MANAGEMENT: abnormalities
• Instruct client to protect themselves from direct
and indirect sunlight to prevent skin burns.
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NURSING CARE PRETRANSPLANT Nursing Management
1. Recipient immunosuppression attained with total
body irradiation (TBI) and chemotherapy to  Trusting relationship, supportive care, and
eradicate existing disease and create space in promotion of hope with the patient and family.
host marrow to allow transplanted cells to grow.  Truthful responses should be given in
2. Provide protective environment.
nonjudgmental manner to questions and
A. Client should be in laminar airflow room or
strict reverse isolation. inquiries about unproven methods.
B. Objects must be sterilized before being  The nurse should encourage any patient who
brought to the room. uses unconventional therapies to inform the
C. When working with children, introduce new physician about such use.
people were they can be seen, but outside child’s
room so they can see what they look like without NURSING MANAGEMENT FOR ONCOLOGIC
isolation garb. EMERGENCIES:

1. SUPERIOR VENA CAVA SYNDROME (SVCS)


3. Monitor central lines frequently. Check patency and
observe signs of infection such as fever, redness around INTERVENTIONS:
sight.  Assess for signs and symptoms of SVCS.
4. Provide care for client receiving chemotherapy and  Monitor cardiopulmonary and neurologic status.
radiation therapy that induce immunosuppression.  Promote energy conservation to minimize
shortness of breath.
NURSING CARE POST TRANSPLANT  Prepare the patient for radiation therapy to the
mediastinal area.
1. Prevent Infection.
2. Provide mouth care for stomatitis and mucositis. 2. SPINAL CORD COMPRESSION
3. Provide skin care.
4. Monitor carefully for bleeding. INTERVENTIONS:
5.Maintain fluid and electrolyte balance and promote  Assess for back pain and neurological deficits.
nutrition.  Prepare the client for radiation and/or
6. Provide client teaching and discharge planning chemotherapy.
concerning:  Surgery may be needed to remove the tumor and
• Home environment (cleaning, pets, visitors) relieve the pressure to spinal cord.
• Diet modifications  Instruct the client in the use of neck or back
• Medication regimen –schedule, dosage, effects, braces if they are prescribed.
side effects.
• Communicable disease and immunizations 3. HYPERCALCEMIA
• Daily hygiene and skin care
• Fever INTERVENTIONS:
• Activity  Monitor calcium level.
 Administer oral or parenteral Normal Saline fluids
9. UNPROVEN & UNCONVENTIONAL THERAPIES as prescribed.
 Administer medications to lower the calcium
• Also called Complementary and Alternative level as prescribed.
Medicine.  Prepare the client for dialysis if the condition
becomes life threatening or is accompanied by
• CAM treatments are the diverse group of medical renal impairment.
and health care systems, practices & products
that are not presently considered to be effective
by the standards of medicine.

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4. PERICARDIAL EFFUSION & CARDIAC TAMPONADE PSYCHOSOCIAL ASPECTS OF CANCER CARE
When cancer becomes a part of life’s journey it is
INTERVENTIONS: hardwork.
 Monitor vital signs and oxygen saturation  Providing support for client (your presence as a
frequently. caring person)
 Assess for pulsusparadoxus.  Providing support for the family
 Monitor ECG tracings  Promoting positive self-concept
 Assess heart and lung sounds.  Promoting coping throughout the cancer
 Monitor and record intake and output continuum
 Elevate the head of patient’s bed.
 Minimize patient’s physical activity. A. Diagnosis and treatment (clients received
 Reposition and encourage the patient to cough. diagnosis and treatment in different ways)
 Provide frequent oral hygiene. B. Survivorship (client who entered successful
 As needed, maintain patient IV access, reorient treatment enter an indeterminate period of long
the patient, and provide supportive measures –term survivorship)
and appropriate patient instruction. C. Recurrent disease and progression (most clients
live with the threat or reality of recurrent
5. DIC/CONSUMPTION COAGULOPATHY disease)
D. Terminal illness, “when everything is done that
INTERVENTIONS: can be done, compassion is the only thing that
 Measure and document Intake & output brings beauty and meaning to our lives. It is the
 Inspect all body orifices & tubes for bleeding irreplaceable gift.
 Prevent bleeding
 Administer anticoagulant as prescribed.
 Administer cryoprecipitated clotting factors if DIC
progress and hemorrhage is the primary problem.

6. SIADH

INTERVENTIONS:
 Monitor accurate recording of intake and output.
 Initiate fluid restriction and increased sodium
intake as prescribed.
 Administer antidiuretic hormone antagonist as
prescribed.
 Monitor serum sodium levels.

7. TUMOR LYSIS SYNDROME

INTERVENTIONS:
 Monitor Intake and Output.
 Encourage oral/IV hydration.
 Administer diuretics as prescribed.
 Administer medications that increase the
excretion of purine as prescribed.
 Prepare to administer IV infusion of glucose
and insulin to treat hyperkalemia.
 Prepare the client for dialysis if hyperkalemia
and hyperuricemia persist despite treatment.

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