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Chromosome 17

Oncogene or
Tumor Suppressor
Leads to errors in Uncontrolled cell Stops regulating tumor supressor
Cancer
DNA growth the cell cycle
Induces apoptosis
Mutatuion
Controls cell
Gene function Makes protein p53
growth Regulates cellular
Most frequently division
Breast cancer
Tp53
mutated gene in human
cancer
Made up of 393 amino
Bladder cancer
Phosphoprotein
acids
Leukemia
Lung cancer
To study the gene's
Tp53 being deleted overall effect on
Many forms of
Ovarian cancer Related health in zebrafish frequency of cancer
cancer stem cells
issues
Melanoma Current studies
being done Study of breast In order to investigate
cancer patients in prevalence of mutated
Colorectal cancer
a Chinese tp53 gene in breast
cancer cases
population
Esophageal cancer

Male infertility

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