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Knorr Pyrazole Synthesis of Edaravone

Chapter · December 2016

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Ana Francisco Ana Sofia M. Ressurreição


University of Lisbon Research Institute for Medicines and Pharmaceutical Sciences
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Maria Perry Francisca Lopes


University of Lisbon University of Lisbon
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Knorr Pyrazole Synthesis of Edaravone

Supplementary Material

Experiment notes
Experimental concerns
Spectra

Experiment notes

Scheme SM 4.2.3.1.1

Scheme SM 4.2.3.1.3

3 4,
5 Scheme SM 4.2.3.1.1

Scheme SM 4.2.3.1.1
Scheme SM
4.2.3.1.2

Scheme SM 4.2.3.1.2

Scheme SM 4.2.3.1.2

Experimental concerns

Figure SM 4.2.3.1.1
Figure SM 4.2.3.1.2

Figure
SM 4.2.3.1.3
Figure SM 4.2.3.1.4
Product analysis, spectra and additional information

Table SM 4.2.3.1.1

Table SM 4.2.3.1.1

Uield Melting point


Class 1
Class 2
Class 3
Class 4
Class 5

Figure
SM 4.2.3.1.4

Scheme SM 4.2.3.1.3

H CH3 H CH3
H

NH N
O N O N

Scheme SM 4.2.3.1.3
H H H J
H H
H
H), H H H
H

Spectra
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