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Psychotherapy © 2012 American Psychological Association

2012, Vol. 49, No. 3, 276 –290 0033-3204/12/$12.00 DOI: 10.1037/a0029564

A Meta-Analysis of Psychodynamic Psychotherapy Outcomes:


Evaluating the Effects of Research-Specific Procedures

Joel M. Town Marc J. Diener


Dalhousie University Long Island University-CW Post

Allan Abbass Falk Leichsenring


Dalhousie University University of Giessen

Ellen Driessen Sven Rabung


VU University of Amsterdam University Medical Center Hamburg-Eppendorf, and
Alpen-Adria-Universität

The aim of this research was to examine the extent to which the use of research-specific procedures in
psychodynamic psychotherapy impacts upon treatment effectiveness and which variables moderate this
potential relationship. Effects of audio/video recording of sessions, use of treatment manuals, and checks
of treatment fidelity were examined. A meta-analysis was conducted on randomized controlled trials of
psychodynamic psychotherapy. Forty-six independent treatment samples totaling 1615 patients were included.
The magnitude of change between pretreatment and posttreatment aggregated across all studies (45 treatment
samples) for overall outcome was large (d៮ ⫽ 1.01), and further improvement was observed between
posttreatment and an average 12.8-month follow-up (d៮ ⫽ 0.18). Subgroup analyses comparing studies that
used research-specific procedures and those that did not revealed that for posttreatment data no differences in
treatment effects were found. However, the use of treatment manuals and fidelity checks were significantly
associated with improvement between the end of treatment and follow-up assessment. Within the limitations
of analyses, this data offered preliminary evidence that use of research-specific procedures does not contribute
in a negative manner to posttreatment outcomes in psychodynamic psychotherapy, and their use contributes
to positive differences that emerge with time. These findings, although observational in nature, make a case
for reconsidering how dimensions of clinical utility and experimental control may be integrated in psychody-
namic psychotherapy to enable further elucidation of principles that evidently work.

Keywords: psychodynamic, psychotherapy, meta-analysis, research, moderator

Supplemental materials: http://dx.doi.org/10.1037/a0029564.supp

Psychotherapy outcome research has evolved to regard the need for mal checks on treatment fidelity. From here on, audio/video record-
adequate specificity and standardization of psychotherapy treatments ing, treatment manuals, and fidelity checks, as a collective are com-
as essential, despite limitations in the generalizability of the controlled monly described as research-specific procedures.
trial methodology (e.g., Blatt & Zuroff, 2005; Roth & Fonagy, 2005). Changes in clinical practice and psychotherapy training (Crits-
Nevertheless, having a true and accurate picture of the nature of a Christoph, Frank, Chambless, Brody, & Karp, 1995) can be traced to
treatment delivered is relevant for controlled research, naturalistic efforts to incorporate these research methods more systematically,
studies, and practice-based evidence more generally to enable a valid moving away from the historical position of less structured methods
assessment of effectiveness. Psychotherapy research and to a lesser and theoretical texts lent from psychoanalysis (Matarazzo & Garner,
extent clinical and training facilities, therefore, now commonly use 1992). However, psychodynamic clinicians and teachers, past and
manual-based treatments, audio/video recording of sessions, and for- present, continue to vary widely in both their attitudes toward these

Joel M. Town and Allan Abbass, Department of Psychiatry, Dalhousie The authors would like to dedicate this article to the memory of Dr.
University, Halifax, Nova Scotia, Canada; Marc J. Diener, Clinical Psychol- Leigh McCullough: With grateful appreciation for Dr. McCullough’s pas-
ogy Doctoral Program, Long Island University—CW Post Brookville, NY, sionate support, collaboration, and a lifetime’s achievements in advancing
USA; Falk Leichsenring, Clinic of Psychosomatics and Psychotherapy, Uni- the field of psychotherapy research and clinical theory, practice, and
versity of Giessen, Giessen, Germany; Ellen Driessen, Department of Clinical training.
Psychology, Faculty of Psychology and Education, VU University of Amster- Correspondence concerning this article should be addressed to Joel M.
dam, Amsterdam, The Netherlands; Sven Rabung, Department of Medical Town, Abbie J. Lane Building, 7th Floor, Room 7516, 5909 Veterans’
Psychology, University Medical Center Hamburg-Eppendorf, Hamburg, Ger- Memorial Lane, Halifax, Nova Scotia B3H 2N1, Canada. E-mail:
many, and University of Klagenfurt, Klagenfurt, Austria. joel.town@dal.ca

276
RESEARCH PROCEDURES META-ANALYSIS 277

Studies included in the 6 select reviews of Psychodynamic therapy:


Abbass (2006) - 23 studies
Abbass (2009) - 14 studies
Diener (2007) - 10 studies
Driessen (2010) - 23 studies
Leichsenring (2011) - 10 studies
Town (2011) - 7 studies

71 independent studies idenfied through a manual review of 6 prior


reviews (excluding 16 duplicate studies included in 2 or more reviews)

30 excluded studies- reasons for exclusion:


23 studies- Criterion of randomized design not fulfilled
7 studies- Study data unavailable

41 independent studies consisng of 46 treatment arms met inclusion


criteria and were included in meta-analysis

Figure 1. Process of selection of trials.

methods and their use of them. Further, the empirical question of technology (Abbass et al., 2011; McCullough, Bhatia, Ulvenes,
whether the requisites of experimental research diverge from the Berggraf, & Osborn, 2011; Manring, Greenberg, Gregory, & Gall-
requisites of good treatment remains unclear. This article examines inger, 2011), prompting the statement that such innovations, “will
the impact on clinical outcome, if any, of using audio/video recording, take psychotherapy training, research, supervision, and treatment
treatment manuals, and treatment fidelity checks in psychodynamic forward toward increased effectiveness” (Barnett, 2011, p. 103).
psychotherapy. However, variation in the use of audio/video equipment by psy-
chodynamic therapists exists, and it would be overly simplistic to
Background suggest that this can be wholly attributed to theories, like that
described earlier, that have since been updated and revised. Other
It has been well-documented that psychodynamic therapists
possible contributory factors relevant to the wider psychotherapy
have historically tended to be antipathetic toward scientific inves-
field include (a) therapists’ and/or supervisors’ anxiety, (b) strain
tigation (Parry, Roth, & Fonagy, 2005). One view is that what can
and pressures that come with set-up and time needed to review
be learnt from current paradigms of research is of limited signif-
tapes, (c) resource limitations preventing access to technology, (d)
icance because of over simplistic attempts to quantify the complex
difficulties guaranteeing confidentiality and/or security of tapes,
mental activity presumed within psychoanalytic theory (Green,
and (e) training deficits/limited knowledge about the technology.
1996). Further objections lie in theoretically based assumptions
Despite the aforementioned possible limitations or “barriers” to
that research methods confound treatment objectives. For example,
audio/video recording, psychodynamically orientated researchers
traditional psychoanalytic theory might assume that audio/video
have described the advantages of using video recording for psy-
recording compromises the neutrality of the therapist, arguably by
chotherapy training purposes (Abbass, 2004; Binder, 1993, 1999;
contributing to the existing therapist–patient power imbalance: the
Hilsenroth, Defife, Blagys, & Ackerman, 2006; Levenson &
sanctity of the therapeutic relationship is sullied, therefore distort-
ing the transference– countertransference matrix. Theoretically, Strupp, 1999), including clinical supervision within psychoana-
this could harm the therapeutic process, enhance patient resistance, lytic programs (Haggerty & Hilsenroth, 2011). As an educational
and impede treatment progress. Assuming iatrogenic effects such experience, video playback enables microanalysis of key in-
as this can and do regularly occur also with use of treatment session events (Aveline, 1992; Binder, 1993; Levenson, 2006), and
manuals and fidelity checks (which empirical data do not currently the opportunity to expose less experienced therapists to treatment
substantiate), more widespread use of psychodynamic treatment nuances. Using recordings, therefore, may help trainees overcome
protocols incorporating these research-specific components is rigid adherence to technique, which can occur at the expense of the
unlikely. therapeutic alliance (Strupp, Butler, & Rosser, 1988). Video re-
cording in particular allows the detection and analysis of subtle
nonverbal cues communicated between patient and therapist that
Audio/Video Recording in Psychodynamic
would otherwise go unnoticed. Furthermore, the use of video
Psychotherapy
playback can enable greater specificity in guiding the timing and
A number of recent articles from psychodynamically trained application of therapeutic technique, providing anchored instruc-
clinicians have highlighted the utility of, and applications for, this tion (Binder, 2004). This is consistent with the finding that use of
278 TOWN ET AL.

video recording within a psychotherapy training program enabled Conclusions about the value of treatment manuals note their
acquisition of psychodynamic techniques (Hilsenroth et al., 2006). limitations but overall support their clinical and training utility as
Haggerty and Hilsenroth (2011) argued that recording therapy a source of “conceptual support” for defining patient problems and
sessions can also minimize the effect of memory limitations (e.g., guiding the content of interventions (Binder et al., 1993; Strupp &
forgetting, misattribution, absent mindedness, bias) that restrict Anderson, 1997). Furthermore, manuals have aided psychotherapy
how accurately session content can be examined using more indi- research efforts to better understand mechanisms of therapeutic
rect methods. change. Treatment manuals have almost become a necessary ele-
Beyond providing a resource that can supplement and facilitate ment in psychotherapy outcome studies (Kazdin, 1994; Kiesler,
the supervisory process, session recording also facilitates the abil- 1994; Lambert & Bergin, 1994); thus, they offer an accepted
ity of therapists to conduct self-analysis (Alpert, 1996; Aveline, medium for operationalizing the independent variable and as such,
1992; Huhra, Yamokoski-Maynhart, & Prieto, 2008; Wolberg, a framework for assessing fidelity.
1954). More generally, therapists’ exposure to videotapes of their
own sessions and those of others promotes increased self-
awareness and improved anxiety tolerance (Abbass, 2004). Al- Treatment Fidelity in Psychodynamic Psychotherapy
though few studies have examined the impact of using recordings,
Treatment fidelity (also commonly referred to as treatment
a recent meta-analysis on the utility of affect-focused techniques in
integrity) refers to the extent to which therapy is delivered as
psychodynamic therapies found that the most robust moderator
intended (Kazdin, 1994). Adherence considers whether the core
variable was the presence of use of audio/videotapes within su-
components or techniques, typically described in a treatment man-
pervision (r ⫽ .29; Diener, Hilsenroth, & Weinberger, 2007).
ual, are implemented, and treatment competence is the skill or
Despite this accumulation of evidence, to our knowledge, the
accuracy with which these interventions are delivered: both com-
empirical question of whether audio/video technology contributes
ponents define treatment fidelity but may be measured separately.
positively or negatively to clinical outcomes has not been formally
Although treatment manuals offer direction for standardizing how
answered (Brown, 1990; Friedmann, Yamamoto, Wolkon, & Da-
therapy can be delivered, formal assessment of treatment imple-
vis, 1978).
mentation usually involves objective review of audio/video record-
ings of sessions: methods may include use of a reliable scale of
Treatment Manuals in Psychodynamic Psychotherapy measurement, independent trained raters, and interrater reliability
calculations.
Psychotherapy treatment manuals provide information on the Empirical research measuring treatment adherence and compe-
nature of the disorder being treated and the specific treatment tence has overall demonstrated no consistent relationship with
strategies and technique, duration, and format to be delivered outcome, irrespective of the adequacy of the methods used. The
(Clarkin, 1998). Early psychodynamic psychotherapy manuals re- lack of effect may be due to the methods used having been
ported time-limited, focal forms of treatment (e.g., Supportive- inadequate to detect an association, or that other treatment char-
Expressive Psychotherapy, Luborsky, 1984; Time-Limited Dy- acteristics, therapist, or patient factors, confound a possible rela-
namic Psychotherapy, Strupp & Binder, 1984), and more recently, tionship with outcome (Perepletchikova & Kazdin, 2005). Leich-
contemporary longer-term treatments have been manualized (e.g., senring et al. (2011, p. 319) concluded that the lack of association
Transference focused psychotherapy, Clarkin, Yeomans, & Kern- could be because fidelity plays a more complex role in the out-
berg, 2006; Mentalization-based treatment, Bateman & Fonagy, come of psychotherapy.
2004). The introduction of manuals, primarily as a research tool According to psychological theory, psychotherapy is intended to
for operationalizing interventions under empirical investigation, relate to therapeutic change. Thus, independent of the result,
appeared to also offer the potential for improving outcomes treatment fidelity is relevant to any discussion on outcome because
through delivering adherent empirically based treatments (Wilson, it can point to the likely validity of statements about effectiveness/
1995, 1996), superior to reliance on the clinical judgment of efficacy (Kazdin, 1994, p. 38). For example, treatment fidelity is
therapists (Drozd & Goldfried, 1996; Wilson, 1998). However, relevant for determining whether (a) a treatment delivered is
based on national practitioner surveys (e.g., Addis & Krasnow, representative of the theoretical constructs and mechanisms pre-
2000), a reluctance to incorporate manualized methods is not sumed to underpin its purpose, (b) the extent to which treatment
unique to psychodynamically informed therapists. Although the effects are causally attributed to the treatment applied, and (c)
merit in common practitioner concerns about manualized ap- whether these methods are generalizable to clinical practice
proaches (Addis, Wade, & Hatgis, 1999) may be questioned (Fon- (Leichsenring et al., 2011).
agy, 1999), the empirical literature indicates that treatment man- Preliminary results from a meta-analysis, albeit with a small
uals do not ensure effective delivery of therapy (Binder, 1993; sample (k ⫽ 9) of studies comparing psychodynamic psychother-
1999; Butler & Strupp, 1993). However, based on a small number apy and CBT, found a positive relationship between psychody-
of studies that produced conflicting results, and given the limita- namic studies reporting treatment fidelity procedures and outcome
tions of study methodology, it is less clear whether that which is (Leichsenring et al., 2011). This was true, however, for only a few
gained in adherence to specific techniques through manuals (Crits- variables (Leichsenring et al., 2011). Although nonsignificant,
Christoph et al., 1998; Henry, Strupp, Butler, Schacht, & Binder, some of the correlations were substantial, corresponding to
1993; Hilsenroth, Defife, Blagys, & Ackerman, 2006; Multon et medium-large effect sizes. This was interpreted as possible evi-
al., 1996) may be at the expense of other therapeutic factors and dence that the implementation of fidelity checks may offer a small
therapeutic progress (Strupp & Anderson, 1997). effect on the outcome for psychodynamic treatment studies. Re-
RESEARCH PROCEDURES META-ANALYSIS 279

search was recommended to confirm a result that could potentially ble 1 Characteristics of reviews). Criteria used for selecting studies
have practice implications for psychodynamic psychotherapy. differed between reviews: One review selected studies with a parallel
group design consisting of a nonactive control arm (Abbass et al.,
Current Study 2006), whereas others included active treatment comparisons (Dries-
sen et al., 2010; Leichsenring & Rabung, 2011; Town et al., 2011).
Psychodynamic psychotherapy clinicians, researchers, and Four of these reviews selected only Short-Term Psychodynamic Psy-
stakeholders alike continue to look for methods, techniques, chotherapy (STPP), excluding studies where the average treatment
and strategies for titrating and improving the size, longevity, and length was greater than 40 therapy sessions (Abbass et al., 2006;
transmissibility of treatment effects. Progress is necessary to in- Abbass, Kisely, & Kroenke, 2009; Driessen et al., 2010; Town et al.,
crease the clinical utility of empirical findings and reduce the 2011), the fifth selected only Long-Term Psychodynamic Psychother-
researcher– clinician gap. Given the aforementioned wide-ranging apies (LTPP) (Leichsenring & Rabung, 2011), and the sixth described
relevance of research-specific procedures, we propose that dis- studies of psychodynamic psychotherapy that presented data relevant
missing their potential application requires demonstrable evidence to therapist facilitation of patient affect experiencing/expression (Die-
that they are associated with significantly worse outcomes. Pro- ner et al., 2007). We also noted that the original searches were
ponents committed to psychodynamic principles regularly use conducted at different times, so additional studies may have since
audio/video recording, treatment manuals, and fidelity checks in been published. However, the literature from which data were se-
clinical trials, though, to our knowledge, no well-controlled clin- lected is representative of a large body of studies (k ⫽ 71) commonly
ical trials exist that used a dismantling procedure to examine the cited on the overall effectiveness of short- and long-term psychody-
possible effects of their use within any psychotherapy modality, namic psychotherapy. We felt this provided a valid rationale for using
psychodynamic, or otherwise. This gap in the literature may con- studies from this list of previously published and recent meta-
tribute to variation in attitudes toward their use and also limits analyses.
conclusions on the effects of such use.
This review will therefore examine empirically the extent to Inclusion Criteria
which use of research-specific procedures in psychodynamic psy-
chotherapy effect outcomes. As a secondary research question, we Having identified studies of interest based on their inclusion in
sought to identify which variables moderate the potential relation- one of the six published reviews on psychodynamic psychother-
ship between the use of these research methods in psychodynamic apy, a second screening process was used to confer eligibility. We
psychotherapy and outcome. included studies in which the psychotherapy treatment (a) was
described by the authors as psychodynamic or psychoanalytic in
Method nature, (b) was provided in an individual or group format (e.g., not
Internet delivered or self-help), and (c) applied verbal techniques
(e.g., treatments using art as a form of expression were excluded).
Selection of Studies
All participants had to be at least 18 years old and considered to
Using extensive searches previously conducted, we selected arti- have a common mental disorder. The latter included anxiety dis-
cles using the list of studies included in the six most recently pub- orders, depressive disorders, stress-related physical conditions, and
lished reviews on psychodynamic psychotherapy conducted by the interpersonal or personality problems mixed with symptom disor-
coauthors (Abbass, Hancock, Henderson, & Kisely, 2006; Abbass, ders. Psychotic disorders were excluded. We only included ran-
Kisely, Kroenke, 2009; Diener et al., 2007; Driessen et al., 2010; domized controlled trials (RCTs) in which psychodynamic psy-
Leichsenring & Rabung, 2011; Town, Abbass, & Hardy, 2011) (Ta- chotherapy was implemented as an active treatment arm and

Table 1
Characteristics of Psychodynamic Therapy Reviews From Which Studies Were Selected

Psychodynamic Date search Studies


Review therapy format Study design Population Databases searched completed included

Abbass et al., 2006 STPP; ⱕ40 sessions; RCT Common mental disorders PsycINFO, CENTRAL, April 2005 23
individual tx MEDLINE, CINAHL,
EMBASE
Abbass et al., 2009 STPP; ⱕ40 sessions; RCT, non-RCT Somatic disorders PsycINFO, MEDLINE, 2007 14
individual tx Cochrane Library
Diener et al., 2007 No restrictions RCT, non-RCT Mixed PsycINFO February 2006 10
Driessen et al., STPP; ⱕ40 sessions; RCT, non-RCT Depressive disorders PsycINFO, PubMed, Cochrane November 2007 23
2010 individual/group Library, EMBASE, Web of
Science
Leichsenring & LTPP; ⬎1 year or RCT, non-RCT Common mental disorders PsycINFO, MEDLINE, Current April 2010 10
Rabung, 2011 50 sessions; Contents
individual/group
Town et al., 2011 STPP; ⱕ40 sessions; RCT Personality disorders PsycINFO, MEDLINE, January 2008 7
individual CINAHL, EMBASE

Note. STPP ⫽ Short-Term Psychodynamic Psychotherapy; LTPP ⫽ Long-Term Psychodynamic Psychotherapy; RCT ⫽ Randomized Controlled Trial.
280 TOWN ET AL.

participants were randomly assigned to treatment. Studies were improvement in the treatment group or negative if the data indi-
excluded if there was insufficient data to enable calculation of cated deterioration in the treatment group. When studies reported
within-group effect sizes. multiple effect sizes that were relevant (e.g., multiple outcome
measures were used), these effect sizes were averaged, following
Data Extraction standard meta-analytic convention (Horvath & Symonds, 1991;
Martin, Garske, & Davis, 2000).
Using a structured and standardized coding scheme, written to The original coding manual distinguished between eight types
specify study characteristics of interest, we (JMT, MJD, AA, ED, of outcome measures. To limit the number of analyses, however,
SR) independently extracted the necessary data for calculation of only the following outcomes were examined in the analyses: (a)
effect sizes alongside the following study information: full study Overall outcome (aggregate of all eight original outcome types),
citation, short- versus long-term treatment length, mean number of (b) General psychiatric symptoms, (c) Anxiety symptoms, (d)
treatment sessions, primary patient diagnostic group, treatment Depressive symptoms, and (e) Personality, that is, a condensed
modality, use of treatment manuals, treatment fidelity checked, outcome variable consisting of the original “Personality function-
outcome informant, use of audio/video recording, and use of ing/traits” outcomes as well as outcome data based on the Inven-
pharmacotherapy. For primary diagnostic group, we included de- tory of Interpersonal Problems (Horowitz, Alden, Wiggins, &
pressive disorders, anxiety disorders, somatoform disorders, and Pincus, 2000).
personality disorders consistent with Diagnostic and Statistical
Manual (4th ed.; DSM–IV; American Psychiatric Association,
1994) categories. A fifth group, “mixed-other disorders,” was Quantitative Data Synthesis
added to ensure that other patient groups from eligible studies were
Effect sizes were aggregated across studies using the random-
captured within the dataset.
effects method of Hedges and colleagues (Hedges & Vevea, 1998).
When necessary, coding ambiguities were discussed and the
Random-effects methods are considered to be more representative
coding manual was revised/clarified as needed. Given the potential
of real-world data (National Research Council, 1992) and yield
ambiguity in coding decisions for the “Outcome type” moderator
results that are more generalizable than their fixed-effect counter-
variable (e.g., “General psychiatric symptoms” vs. “depressive
parts (Hedges & Vevea, 1998). These calculations were performed
symptoms,” etc.), the first (JMT) and third author (AA) recoded all
using version 2 of the Comprehensive Meta-Analysis (CMA;
data for this variable. Kappa coefficients calculated to check
Borenstein et al., 2005) software. Cohen’s (1988) benchmarks for
interrater reliability between raters were excellent (Cohen’s ␬ ⫽
the magnitude of effect sizes were selected to aid in interpreting
0.95). Any discrepancies between these ratings and the original
the results. Homogeneity tests and related analyses (e.g., calcula-
ones were resolved via consensus discussion.
tion of I2) were conducted to examine the degree of variation
In the case of nine papers (Cooper, Murray, Wilson, & Roma-
between effect sizes (Borenstein et al., 2009). All reported p values
niuk, 2003; de Jonghe et al., 2004; Hamilton et al., 2000; Linnet
in the present study are two-tailed unless otherwise noted.
and Jemec, 2001; Maina et al., 2005; Monsen & Monsen, 2000;
Shapiro et al., 1994/Hardy et al., 1995; Svartberg, Stiles, & Seltzer,
2004; Winston et al., 1994), ratings were completed by two coders Moderator Analyses
because of overlap of studies in the authors’ respective databases.
Interrater reliability was computed for categorical data with the Because the primary analyses of the present study involved
kappa coefficient, and all values (range ⫽ 0.84 to 1.0) were in the outcome comparisons between studies that did versus did not use
excellent range (⬎0.74; Fleiss, 1981). Intraclass correlation coef- a particular methodological variable (e.g., recordings), all moder-
ficients (ICC) for ratings of mean treatment length also demon- ator analyses were conducted by comparing outcomes for studies
strated excellent agreement between raters (ICC[2,1] ⫽ 1.0; that did and did not use that methodological variable separately for
Shrout & Fleiss, 1979). Discrepancies in ratings were resolved via each of the relevant moderator variable levels. Thus, for example,
consensus discussion. in examining the moderator impact of use of treatment manuals on
Effect size calculation consisted of within-group standardized the use of recordings, outcomes for studies that used recordings
mean difference scores using Equations 4.18 – 4.19 from Boren- were compared with outcomes for studies that did not use record-
stein, Hedges, Higgins, and Rothstein (2009; Abbass, Town, & ings, first for studies that did use treatment manuals and then for
Driessen, 2012; cf., Dunlap, Cortina, Vaslow, & Burke, 1996), and studies that did not use such manuals.
the standard error was calculated using Equations 4.20 – 4.21 from Continuous moderator analyses were conducted using mixed-
Borenstein et al. (2009). effects (method of moments) meta-regression analyses for effect
Effect sizes were calculated for both pre–post outcomes and size data aggregated across all outcomes only and for pre-post data
posttreatment-follow up outcomes (when available). In cases in only, with the average effect size for each study serving as the
which multiple follow-ups were reported, the longest time period dependent variable and each continuous moderator variable serv-
for follow-up was selected, with one exception: The follow-up ing as a covariate. Because CMA software will not conduct a
period selected for Bateman and Fonagy (2001) was the 18-month multiple meta-regression analysis, each covariate was examined
follow-up. Although there is an additional 8-year follow-up avail- using a separate meta-regression. Meta-regression analyses were
able for this study (Bateman & Fonagy, 2008), the 18-month performed using the following moderators as predictor variables of
follow-up was selected because this interval is more commonly effect size: (a) Publication year, and (b) Mean number of treatment
used to evaluate treatment effects than the longer, 8-year alterna- sessions. When this latter information was not explicitly reported
tive. Effect sizes were coded as positive if the data indicated or when data were not provided to allow calculation of mean, the
RESEARCH PROCEDURES META-ANALYSIS 281

planned/estimated number of treatment sessions based on treat- 1995; Creed et al., 2003; Guthrie, Creed, Dawson, & Tomenson,
ment completion was used. 1993; Morris, 1975; Piper, Azim, McCallum, & Joyce, 1990;
For all categorical moderator analyses, Q tests, analogous to Sjodin, 1983; Svedlund, Sjodin, Ottosson, & Dotevall, 1983).
analysis of variance in primary research (Borenstein et al., 2009; Hardy et al. (1995) was excluded because data were reported on a
Lipsey & Wilson, 2001), were calculated to determine whether the subsample of Shapiro et al. (1994). This process yielded 41 inde-
various levels of the moderator variable differed significantly from pendent RCTs of psychodynamic psychotherapy suitable for in-
each other. When all subgroups in a particular analysis had at least clusion and meta-analysis. Within this literature, five studies (Clar-
six studies, estimates of the variance of true effect sizes were not kin, Levy, Lenzenweger, & Kernberg, 2007; Huber and Klug,
pooled; when at least one subgroup, however, had fewer than six 2006; Knekt et al., 2008; Vinnars, Barber, Noren, Gallop, &
studies, estimates of the variance of true effect sizes were pooled Weinryb, 2005; Winston et al., 1994) reported two psychotherapy
because the accuracy yielded by pooling is likely to be greater than arms described as psychodynamic or psychoanalytic in origin and
any real differences between subgroups (Borenstein et al., 2009). thus eligible for inclusion as forms of psychodynamic psychother-
When examining the impact of audio/video recordings, categorical apy. In total, 46 psychodynamic psychotherapy treatment groups
analyses were conducted for each of the following moderator vari- were available for analysis. (A complete reference list for all
ables: (a) Use of pharmacotherapy (e.g., antidepressant medication): meta-analysed studies is available in a data supplement that ac-
yes (medication use was allowed during treatment and/or follow-up), companies the online version of this article.)
no (medication use was not permitted during treatment or follow-up), Study characteristics. The 46 independent psychodynamic
or unclear (it was unclear whether or not medication use was permit- psychotherapy treatment samples consisted of 1,615 subjects. The
ted during treatment and/or follow-up); (b) Use of a treatment manual: mean number of subjects per treatment sample was 35 (SD ⫽ 28),
yes or no (regarding use of treatment manual reported in methodol- and the range was 8 to 128.1 The included studies reported on
ogy); (c) Treatment fidelity: None (i.e., fidelity checks of treatment subjects displaying a range of common mental health presenta-
were reported, and psychodynamic treatment was shown to not be tions. The primary diagnostic groups treated were categorized as
delivered as required by the study; note that no studies in the present Depressive disorders (k ⫽ 15), Anxiety disorders (k ⫽ 4), Soma-
meta-analysis were given this rating), Unknown (i.e., fidelity checks toform disorders (k ⫽ 5), Personality disorders (k ⫽ 13), and
were not reported on the psychodynamic treatment), Confirmed (i.e., mixed/other disorder (k ⫽ 9).
fidelity checks of treatment were reported, and psychodynamic treat- The majority of studies (k ⫽ 38) reported psychodynamic psy-
ment was shown to be delivered as required by the study); (d) chotherapy with an average treatment length of ⱕ40 sessions
Treatment length: Short-term (ⱕ40 sessions) versus long-term (⬎40 (short-term), whereas eight studies averaged ⬎40 sessions (long-
sessions). When examining the impact of use of a treatment manual, term) in treatment duration. One study described a group-based
categorical analyses were conducted for the following moderators: (a) psychodynamic intervention (Liberman and Eckman, 1981), and
Use of audio/video recording; (b) Use of pharmacotherapy; (c) Treat- all other treatments were delivered in an individual format. Audio
ment fidelity; (d) Treatment length. Finally, when examining the or video recording of psychodynamic treatment sessions was im-
impact of treatment fidelity, categorical analyses were conducted for plemented in 24 studies, and not used or not reported in 22 studies.
the following moderators: (a) Use of audio/video recording; (b) Use Manualized psychodynamic treatments were used in 33 studies,
of pharmacotherapy; (c) Use of a treatment manual; (d) Treatment whereas 13 did not report the use of a treatment manual. Treatment
length. fidelity checks were conducted in more than half of the included
studies (k ⫽ 25) and not checked or reported in others (k ⫽ 21).
Publication Bias Although a standardized method for evaluating study quality
was not used here, several points on the methodology of the studies
Potential publication bias of the overall meta-analysis was as-
can be highlighted. Because only RCTs were included, all studies
sessed in multiple ways including (a) Begg and Mazumdar’s
used random assignment to allocate subjects to condition. The
(1994) rank correlation, (b) Egger’s regression intercept (Egger,
assessment of treatment outcome at follow-up was present in 31
Davey Smith, Schneider, & Minder, 1997), and (c) Duval and
studies (average follow-up on overall outcome ⫽ 12.8 months,
Tweedie’s (2000a, 2000b) trim and fill procedure.
SD ⫽ 9.2). Pharmacotherapy (e.g., use of antidepressants) was

Results
1
Not every effect size or every study included in the present meta-
Inclusion of Studies analytic review was included in each analysis since, for example, separate
analyses were conducted for pre–post versus posttreatment/follow-up ef-
The initial search, screening studies included in six previously fect sizes and Cooper et al. (2003) provided only posttreatment/follow-up
conducted reviews of the psychodynamic psychotherapy literature, data. The descriptive data reported in the main body of the article provide
resulted in the identification of 71 independent trials (this did not the numbers aggregated across every study and every effect size, and so
include 16 duplicate studies included in one or more of the 6 they are not indicative of the actual sample sizes for particular analyses in
the present study. The analysis with the largest sample size was the overall
original reviews). In the second phase, the full-text of each trial
meta-analysis for psychodynamic psychotherapy using pre–post effect
was screened by one of the authors for the presence of this sizes. This analysis included 45 independent treatment samples from 42
review’s inclusion and exclusion criteria. Twenty-three studies peer-reviewed journal articles as well as one book chapter (plus unpub-
were excluded because the criterion of randomized design was not lished data for that book chapter) made up of 40 RCTs. The total number
fulfilled. Seven studies were excluded because the necessary data of participants for this specific analysis was 1,613, with a range of sample
to enable effect size calculation were not available (Baldoni et al., sizes from 13 to 116, and a mean sample size of 36 (SD ⫽ 29).
282 TOWN ET AL.

permitted in 23 studies, not permitted in 13, and it was unclear results from Duval and Tweedie’s (2000a, 2000b) trim and fill pro-
whether medication was monitored in the remaining 10 studies. cedure suggested that the impact of potential publication bias would
likely be minimal even if it did exist (zero studies trimmed; adjusted
Quantitative Data Synthesis and observed estimates of effect size were identical).
For posttreatment to follow-up change, publication bias results
Effect sizes of psychodynamic psychotherapy. Including all suggested some potential for publication bias using Egger’s (Egger
of the 45 conditions of psychodynamic psychotherapy, results et al., 1997) intercept method (intercept ⫽ 1.11, p[one-tailed] ⫽
indicated a large magnitude of change in outcome from pretreat- .05), and only a trend toward significance for Begg and Mazum-
ment to posttreatment when all outcome measures were aggre-
dar’s (1994) approach (Kendall’s tau [with continuity correction] ⫽
gated, and that this change was statistically significant (d៮ ⫽ 1.01,
0.17, p[one-tailed] ⫽ .099). Results from Duval and Tweedie’s
95% confidence interval [CI] ⫽ 0.86 –1.16, p ⬍ .001). Results also
(2000a, 2000b) trim and fill procedure indicated that the impact of
indicated demonstrable heterogeneity across effect sizes (Q[44] ⫽
any potential publication bias would likely be minimal even if it
157.51, p[one-tailed] ⬍ .001), and the degree of variation that
did exist (zero studies trimmed; adjusted and observed estimates of
could be attributed to true differences between effect sizes fell in
effect size were identical).
the medium to large range (I2 ⫽ 72.07, ␶2 ⫽ 0.17, ␶ ⫽ 0.42;
Utility of audio/video recordings by outcome type. Table 3
Higgins, Thompson, Deeks, & Altman, 2003). This heterogeneity
summarizes all effect sizes and test statistics for each outcome
is examined further by the attempt described later to identify
category and type of contrast for pre–post change. The pooled
moderator variables that could account for observed differences
effect size indicating the size of the change in overall outcome in
between effect sizes.
studies with audio/video recording was 0.92 (95% CI ⫽ 0.71–1.14,
For outcomes measured between posttreatment and follow-up,
the effect size was 0.18 (95% CI ⫽ 0.07– 0.29), indicating a p ⬍ .001) and 1.11 (95% CI ⫽ 0.90 –1.32, p ⬍ .001) when
statistically significant improvement in overall outcome (p ⫽ recording was absent. Across each of the four individual outcome
.002). There was no demonstrable heterogeneity across effect sizes categories, the effect size for pre–post change was also large (d៮ ⬘s
(Q[29] ⫽ 37.40, p[one-tailed] ⫽ .14), and the degree of variation ranging from 0.85 to 1.32) and statistically significant both in
that could be attributed to true differences between effect sizes fell studies that utilized audio/video recordings as well as studies that
slightly below Higgins et al.’s (2003) benchmark for small (I2 ⫽ did not; the one exception was personality functioning, for which
22.46, ␶2 ⫽ 0.02, ␶ ⫽ 0.15). studies that used audio/video recording demonstrated a statistically
The treatment effects in psychodynamic psychotherapy seen significant effect in the medium–large range (d៮ ⫽ 0.63, 95% CI ⫽
between pre- and posttreatment (see Table 2) were also calculated 0.38 – 0.89, p ⬍ .001).
specifically for different outcome domains, with results ranging The comparison for effect size between studies that did use record-
from 0.75 to 1.20, all ps ⬍ .001. These analyses found statistically ings and those that did not was not statistically significant for any
significant change in outcome scores that were in the large range, outcome type, though a small effect indicating potentially better
and approaching the conventional 0.80 cutoff for personality func- outcomes was found in studies that did not use audio/video recording
tioning. At pretreatment to follow-up, change in personality func- for depressive symptoms (⌬d៮ ⫽ 0.22) and personality functioning
tioning was large (d៮ ⫽ 0.96, 95% CI ⫽ 0.60 –1.27, p ⬍ .001). We (⌬d៮ ⫽ 0.30).
calculated changes in outcomes from posttreatment to follow-up. Table 4 summarizes all effect sizes and test statistics based on
Effect sizes ranged from 0.22 to 0.50, all ps ⬍ .05, indicating posttreatment to follow-up contrasts for individual outcome types. A
small, but significant, improvement across all outcome domains. comparison for anxiety symptoms was not conducted because only a
Publication bias for overall effect sizes. Results indicated no single study was coded as using audio/video recording. Comparisons
demonstrable evidence of publication bias for the overall meta- of within-group contrasts at posttreatment to follow-up revealed sta-
analysis of pre–post outcome using either Begg and Mazumdar’s tistically significant improvement with and without audio/video re-
(1994) rank correlation method (Kendall’s tau [with continuity cor- cording when all outcomes were aggregated together (d៮ ⫽ 0.21, 95%
rection, Borenstein, Hedges, Higgins, & Rothstein, 2005] ⫽ 0.13, CI ⫽ 0.01– 0.41, p ⫽ .042; and d៮ ⫽ 0.16, 95% CI ⫽ 0.02– 0.31, p ⫽
p[one-tailed] ⫽ .10) or Egger’s (Egger et al., 1997) regression inter- .030; respectively). For individual outcome domains analyzed, results
cept method (intercept ⫽ 0.79, p[one-tailed] ⫽ .16). In addition, ranged from 0.09 to 0.42; see Table 4 for more details).

Table 2
Random Effects Meta-Analysis of Psychodynamic Psychotherapy: Pre- to Posttreatment and Posttreatment to Follow-Up Change

Pre–post treatment Post/follow-up

k d៮ 95% CI Z value p k d៮ 95% CI Z value p



Overall 45 1.01 0.86–1.16 13.12 ⬍.001 30 0.18 0.07–0.29 3.11 .002ⴱ
Depression 28 1.20 1.0–1.40 11.76 ⬍.001ⴱ 14 0.24 0.04–0.44 2.39 .017ⴱⴱ
Anxiety 18 0.87 0.67–1.07 8.41 ⬍.001ⴱ 11 0.50 0.04–1.0 2.11 .035ⴱⴱ
Personality functioning 20 0.75 0.50–0.99 6.02 ⬍.001ⴱ 12 0.25 0.01–0.48 2.04 .041ⴱⴱ
General psychiatric 31 1.07 0.87–1.27 10.4 ⬍.001ⴱ 19 0.22 0.07–0.36 2.96 .003ⴱ
ⴱ ⴱⴱ
p ⬍ .01. p ⬍ .05.
RESEARCH PROCEDURES META-ANALYSIS 283

Table 3
Random Effects Meta-Analysis of Psychodynamic Psychotherapy by Use of Audio/Video Recordings: Within-Group Change and
Between-Group Differences for Pre- to Posttreatment Outcomes

Within-group Between-group

Subgroup k d៮ 95% CI Z-value p ⌬d a Q-value p

Overall
A/V 24 0.92 0.71–1.14 8.38 ⬍.001ⴱ ⫺0.19 1.45 .229
No A/V 21 1.11 0.90–1.32 10.32 ⬍.001ⴱ
Depression
A/V 15 1.10 0.82–1.37 7.79 ⬍.001ⴱ ⫺0.22 1.19 .275
No A/V 13 1.32 1.03–1.61 8.80 ⬍.001ⴱ
Anxiety
A/V 6 0.93 0.56–1.29 5.01 ⬍.001ⴱ 0.08 0.12 .732
No A/V 12 0.85 0.59–1.10 6.51 ⬍.001ⴱ
Personality functioning
A/V 13 0.63 0.38–0.89 4.85 ⬍.001ⴱ ⫺0.30 1.20 .274
No A/V 7 0.93 0.46–1.39 3.91 ⬍.001ⴱ
General psychiatric
A/V 16 0.98 0.64–1.31 5.64 ⬍.001ⴱ ⫺0.17 0.70 .402
No A/V 15 1.15 0.92–1.38 9.93 ⬍.001ⴱ

Note. ⌬d ⫽ the magnitude of difference in outcome between studies that did use audio-visual recording and studies that did not do so.
a
Positive effect sizes indicate differences in favor of use of research-specific procedure.

p ⬍ .001.

Based on between-groups comparisons at posttreatment to follow- when treatment manuals were absent. Across each of the four indi-
up, a small effect size was found for personality functioning favoring vidual outcome categories, the effect size for pre–post change was
use of audio/video recording (⌬d៮ ⫽ 0.33). All between-groups sta- also large (d៮ ⬘s ranging from 0.82 to 1.28) and statistically significant
tistical comparisons were, however, nonsignificant. both in studies that used treatment manuals as well as studies that did
Utility of treatment manuals by outcome type. Table 5 not; the one exception was personality functioning, for which studies
summarizes all effect sizes and test statistics for each outcome cate- that used treatment manuals (d៮ ⫽ 0.74, 95% CI ⫽ 0.41–1.06, p ⬍
gory and type of contrast for pre–post change. The pooled effect size .001) as well as studies that did not use treatment manuals (d៮ ⫽ 0.78,
for overall outcome in studies with treatment manuals was 0.98 (95% 95% CI ⫽ 0.48 –1.09, p ⬍ .001) both demonstrated a statistically
CI ⫽ 0.79 –1.17, p ⬍ .001) and 1.08 (95% CI ⫽ 0.82–1.35, p ⬍ .001) significant effect in the medium–large range.

Table 4
Random Effects Meta-Analysis of Psychodynamic Psychotherapy by Use of Audio/Video Recordings: Within-Group Change and
Between-Group Differences for Posttreatment to Follow-Up Outcomes

Within-group Between-group

Subgroup k d៮ 95% CI Z-value p ⌬d a Q-value p

Overall
A/V 14 0.21 0.01 to 0.41 2.04 .042ⴱ 0.05 0.14 .707
No A/V 16 0.16 0.02 to 0.31 2.17 .030ⴱ
Depression
A/V 6 0.27 ⫺0.13 to 0.67 1.33 .185 0.06 0.06 .808
No A/V 8 0.21 0.01 to 0.41 2.08 .037ⴱ
Anxietyb
A/V — — — — — — — —
No A/V — — — — — — — —
Personality functioning
A/V 6 0.42 ⫺0.04 to 0.88 1.78 .076 0.33 1.61 .205
No A/V 6 0.09 ⫺0.12 to 0.30 0.84 .403
General psychiatric
A/V 8 0.25 ⫺0.06 to 0.56 1.58 .115 0.03 0.02 .878
No A/V 11 0.22 0.05 to 0.39 2.56 .010ⴱ

Note. ⌬d ⫽ the magnitude of difference in outcome between studies that did use audio-visual recording and studies that did not do so.
a
Positive effect sizes indicate differences in favor of use of research-specific procedure. b The comparison for anxiety symptoms was not conducted
because only a single study was coded as using audio/video recording.

p ⬍ .05.
284 TOWN ET AL.

Table 5
Random Effects Meta-Analysis of Psychodynamic Psychotherapy by Use of Treatment Manual: Within-Group Change and
Between-Group Differences for Pre- to Posttreatment Outcomes

Within-group Between-group

Subgroup k d៮ 95% CI Z-value p ⌬d a Q-value p

Overall
Manual 32 0.98 0.79–1.17 10.28 ⬍.001ⴱ ⫺0.10 0.39 .533
No manual 13 1.08 0.82–1.35 8.03 ⬍.001ⴱ
Depression
Manual 18 1.16 0.90–1.41 8.87 ⬍.001ⴱ ⫺0.12 0.33 .565
No manual 10 1.28 0.94–1.62 7.41 ⬍.001ⴱ
Anxiety
Manual 11 0.98 0.64–1.31 5.74 ⬍.001ⴱ 0.16 0.63 .426
No manual 7 0.82 0.61–1.02 7.75 ⬍.001ⴱ
Personality functioning
Manual 14 0.74 0.41–1.06 4.47 ⬍.001ⴱ ⫺0.04 0.04 .838
No manual 6 0.78 0.48–1.09 4.97 ⬍.001ⴱ
General psychiatric
Manual 24 1.04 0.78–1.31 7.72 ⬍.001ⴱ ⫺0.09 0.20 .656
No manual 7 1.13 0.86–1.39 8.42 ⬍.001ⴱ

Note. ⌬d ⫽ the magnitude of difference in outcome between studies that did use treatment manuals and studies that did not do so.
a
Positive effect sizes indicate differences in favor of use of research-specific procedure.

p ⬍ .001.

All comparisons for effect size between studies that did use treatment manuals ranged from 0.25 to 0.71, all ps ⬍ .05 (see
treatment manuals and those that did not were not statistically Table 6 for details). All between-groups statistical comparisons
significant for any outcome type, and effects fell short of the were nonsignificant, although a medium effect size for anxiety
conventional benchmark for a small effect (i.e., all ⌬ds ⬍ 0.20). symptoms was obtained favoring use of treatment manuals (⌬d៮ ⫽
Table 6 summarizes all effect sizes and test statistics based on 0.56).
posttreatment to follow-up contrasts for individual outcome types. Utility of fidelity checks by outcome type. Table 7 sum-
Within-group contrasts revealed statistically significant improve- marizes all effect sizes and test statistics for each outcome
ment but only for studies that used treatment manuals (d៮ ⫽ 0.22, category and type of contrast for pre–post change. The pooled
95% CI ⫽ 0.06 – 0.37, p ⫽ .007) for overall outcome. Similarly, effect size indicating the size of the change in overall outcome
effect sizes for the individual outcome domains in studies that used in studies with confirmed fidelity was 1.03 (95% CI ⫽ 0.81–

Table 6
Random Effects Meta-Analysis of Psychodynamic Psychotherapy by Use of Treatment Manuals: Within-Group Change and
Between-Group Differences for Posttreatment to Follow-Up Outcomes

Within-group Between-group

Subgroup k d៮ 95% CI Z-value p ⌬d a Q-value p

Overall
Manual 21 0.22 0.06 to 0.37 2.71 .007ⴱ 0.10 0.59 .441
No manual 9 0.12 ⫺0.08 to 0.31 1.20 .230
Depression
Manual 10 0.26 0.02 to 0.50 2.16 .031ⴱⴱ 0.07 0.11 .744
No manual 4 0.19 ⫺0.21 to 0.58 0.91 .363
Anxiety
Manual 7 0.71 0.11 to 1.31 2.33 .020ⴱⴱ 0.56 1.26 .261
No manual 4 0.15 ⫺0.64 to 0.93 0.36 .717
Personality functioning
Manual 7 0.33 0.01 to 0.66 2.02 .043ⴱⴱ 0.19 0.60 .440
No manual 5 0.14 ⫺0.25 to 0.52 0.70 .484
General psychiatric
Manual 14 0.25 0.07 to 0.43 2.74 .006ⴱ 0.09 0.29 .593
No manual 5 0.16 ⫺0.12 to 0.44 1.11 .027

Note. ⌬d ⫽ the magnitude of difference in outcome between studies that did use treatment manuals and studies that did not do so.
a
Positive effect sizes indicate differences in favor of use of research-specific procedure.

p ⬍ .001. ⴱⴱ p ⬍ .05.
RESEARCH PROCEDURES META-ANALYSIS 285

Table 7
Random Effects Meta-Analysis of Psychodynamic Psychotherapy by Fidelity: Within-Group Change and Between-Group Differences
for Pre- to Posttreatment Outcomes

Within-group Between-group

Subgroup k d៮ 95% CI Z-value p ⌬d a Q-value p

Overall
Fidelityb 24 1.03 0.81–1.25 9.05 ⬍.001ⴱ 0.04 0.07 .796
No fidelityc 21 0.99 0.79–1.20 9.48 ⬍.001ⴱ
Depression
Fidelityb 13 1.14 0.83–1.44 7.29 ⬍.001ⴱ ⫺0.12 0.33 .567
No fidelityc 15 1.26 0.99–1.52 9.21 ⬍.001ⴱ
Anxiety
Fidelityb 5 1.14 0.74–1.54 5.63 ⬍.001ⴱ 0.35 2.36 .124
No fidelityc 13 0.79 0.54–1.01 6.51 ⬍.001ⴱ
Personality functioning
Fidelityb 11 0.68 0.40–0.96 4.76 ⬍.001ⴱ ⫺0.13 0.27 .607
No fidelityc 9 0.81 0.39–1.22 3.81 ⬍.001ⴱ
General psychiatric
Fidelityb 16 1.02 0.67–1.37 5.75 ⬍.001ⴱ ⫺0.09 0.18 .675
No fidelityc 15 1.11 0.89–1.33 10.04 ⬍.001ⴱ

Note. ⌬d ⫽ the magnitude of difference in outcome between studies with confirmed treatment fidelity and studies without reported treatment fidelity
checks.
a
Positive effect sizes indicate differences in favor of use of research-specific procedure. b Indicates studies that conducted treatment fidelity
checks. c Indicates studies that did not report treatment fidelity checks.

p ⬍ .001.

1.25, p ⬍ .001) and 0.99 (95% CI ⫽ 0.79 –1.20, p ⬍ .001) when change in pretreatment to posttreatment scores for overall outcome.
treatment fidelity checks were not reported. Effect sizes for Only a single study was coded as not using a treatment manual that
individual outcome domains ranged from 0.68 to 1.26, all of had confirmed fidelity. Similarly, only a single study was coded for an
which were statistically significant (all ps ⬍ .001; see Table 7 absence of treatment manual but presence of audio/video recording.
for details). These sets of analyses were therefore not conducted. Moderator
The comparison for effect size between studies with confirmed results showed that no categorical analyses yielded a medium effect
fidelity versus studies that did not report fidelity checks was not size (i.e., all ⌬d៮ ⬘s ⬍ 0.50; no p values could be computed for these
statistically significant for any outcome type. Effect size calcula- analyses because the meta-analytic software cannot calculate moder-
tion of the magnitude of between-groups comparisons found a ator analyses for subgroup data; the ⌬d៮ ⬘s were calculated by subtract-
small effect for anxiety symptoms (⌬d ⫽ 0.35) favoring studies ing the relevant difference scores).2 In addition, all meta-regressions
with confirmed fidelity. using the mean number of treatment sessions or the year of publica-
Table 8 summarizes all effect sizes and test statistics based on tion did not significantly predict outcomes for studies that did have
posttreatment to follow-up contrasts for individual outcome types. any of the research-specific variables (all ps ⬎ .05); the same was true
Comparison of within-group contrasts at posttreatment to follow-up for all meta-regressions for studies that did not have any of the
revealed statistically significant improvement in four of five analyses research-specific variables.
for studies with confirmed fidelity (see table for specifics). Statisti-
cally significant within-group contrasts at posttreatment to follow-up
Discussion
in studies where fidelity checks were not conducted were only present
for general psychiatric symptoms (d៮ ⫽ 0.20, 95% CI ⫽ 0.02– 0.38, There is mounting evidence from recent meta-analyses that dem-
p ⫽ .031) and depressive symptoms (d៮ ⫽ 0.23, 95% CI ⫽ 0.01– 0.46, onstrate the effectiveness of psychodynamic psychotherapy (Abbass
p ⫽ .045). et al., 2006; Abbass et al., 2009; Driessen et al., 2010; Leichsenring &
Based on between-groups comparisons at posttreatment to
follow-up, a statistically significant difference was found for anx-
2
iety symptoms with a magnitude of a large effect size favoring For example, to examine the moderating role of treatment length on the
studies with confirmed fidelity (⌬d៮ ⫽ 1.40, p ⫽ .004). All remain- impact of audio/video recording, studies that did not use audio/video
ing between-groups statistical comparisons were, however, non- recording (d៮ ⫽ 1.00) were compared with studies that did use audio/video
significant. recording (d៮ ⫽ 0.92) for the group of studies that had short-term treatment.
The difference associated with use of recording is therefore 1.00 ⫺ 0.92 ⫽
Moderator analyses of the impact of research-specific pro-
0.08 for studies with short-term treatments. Next, studies that did not use
cedures. We conducted moderator analyses (for each respective audio/video recordings (d៮ ⫽ 1.38) were compared with studies that did use
research procedure, we considered the effect of (a) audio-video re- audio/video recordings (d៮ ⫽ 0.94) for the long-term treatments only. These
cording/treatment manual/treatment fidelity checks [where applica- yields a difference score of 1.38 ⫺ 0.94 ⫽ 0.44. When the previously
ble]; (b) pharmacotherapy use; (c) treatment length; (d) mean number mentioned difference score of 0.08 is subtracted from this difference score
of treatment sessions), including all studies, with outcome defined as of 0.44, the resulting effect size is 0.36.
286 TOWN ET AL.

Table 8
Random Effects Meta-Analysis of Psychodynamic Psychotherapy by Fidelity: Within-Group Change and Between-Group Differences
for Posttreatment to Follow-Up Outcomes

Within-group Between-group

Subgroup k d៮ 95% CI Z-value p ⌬d a Q-value p

Overall
Fidelityb 17 0.22 0.04 to 0.40 2.41 .016ⴱⴱ 0.08 0.39 .535
No fidelityc 13 0.14 ⫺0.02 to 0.31 1.70 .089
Depression
Fidelityb 8 0.27 ⫺0.06 to 0.59 1.58 .113 0.04 0.02 .880
No fidelityc 6 0.23 0.01 to 0.46 2.00 .045ⴱⴱ
Anxiety
Fidelityb 3 1.54 0.72 to 2.35 3.69 ⬍.001ⴱ 1.40 8.50 .004ⴱ
No fidelityc 8 0.14 ⫺0.34 to 0.61 0.56 .574
Personality functioning
Fidelityb 7 0.33 0.01 to 0.66 2.02 .043ⴱⴱ 0.19 0.60 .440
No fidelityc 5 0.14 ⫺0.25 to 0.52 0.70 .484
General psychiatric
Fidelityb 10 0.27 0.00 to 0.54 1.98 .047ⴱⴱ 0.07 0.18 .669
No fidelityc 9 0.20 0.02 to 0.38 2.15 .031ⴱⴱ

Note. ⌬d ⫽ the magnitude of difference in outcome between studies with confirmed treatment fidelity and studies without reported treatment fidelity
checks.
a
Positive effect sizes indicate differences in favor of use of research-specific procedure. b Indicates studies that conducted treatment fidelity
checks. c Indicates studies that did not report treatment fidelity checks.

p ⬍ .01. ⴱⴱ p ⬍ .05.

Rabung, 2011; Town et al., 2011). The reoccurring finding that personality functioning (⌬ds ranging from .19 to .33), which appear
therapeutic gains may not only be maintained after psychodynamic after treatment is completed.
treatment but they continue to improve with time is especially note- The use of audio/video recording, treatment manuals, and fidelity
worthy (Shedler, 2010). Based on the results from the current meta- checks in psychodynamic psychotherapy can be controversial. Based
analysis of only randomized controlled trials including 46 psychody- on some proponents of psychoanalytic theory, everything else being
namic psychotherapy treatment samples (d៮ ⫽ 1.01 for pre–post equal, one might suppose negative effects. The limitations of this
overall outcome; d៮ ⫽ .18 for overall outcome between posttreatment conceptual argument may be questioned, given other proponents
and an average of 12.8 months of follow-up), we now believe there is clearly committed to psychodynamic principles regularly incorporate
unambiguous empirical support for these findings. Evidence of con- audio/video recording, manualized treatments, and fidelity checks in
tinued gains posttreatment is of particular importance because it clinical trials. Given the absence of statistically significant differences
suggests that under the right circumstances, psychotherapy may fa- in posttreatment effects, overall, the current findings suggest the use
cilitate changes in the underlying psychological structures and intra- of these methods, at this time, is not demonstrably associated with
psychic processes presumed to mediate psychopathology, thus en- either better or worse outcomes at the end of therapy in efficacy trials.
abling long-lasting benefits that translate to the real world, far beyond If you consider the magnitude of the difference in treatment effects
and after therapy is complete. But, crucially much remains unknown between studies rather than rely solely on the criteria of whether they
about the precise mechanisms of psychotherapeutic change (Kazdin, reached statistical significance, this revealed some limited (nonsignif-
2007). Toward this goal, treatment protocols may use procedures such icant) differences based on the use of audio/video equipment. Of the
as audio/video recording, treatment manuals, and fidelity checks that five pre- to posttreatment between-group comparisons, two fell in the
allow specification of what is actually delivered in psychotherapy. To range of a small effect indicating better outcomes for the studies that
examine the utility and impact of these methods on treatment effec- did not use audio/video recording (⌬d ⫽ .22 for depressive symp-
tiveness in psychodynamic psychotherapy, in this meta-analysis, we toms; ⌬d ⫽ .30 for personality functioning). At follow-up, however,
conducted individual subgroup analyses to compare treatment effects this trend was not observed; by contrast, studies that used audio/video
in studies using recording equipment, treatment manuals, and fidelity recording demonstrated better outcomes for personality functioning
checks versus psychodynamic psychotherapy in which each respec- (⌬d ⫽ .33).
tive procedure was absent. Within the limitations of these analyses, The potential benefits of recording psychotherapy sessions for
which require results to be considered observational in nature, all purposes of retrospective review (Abbass, 2004; Alpert, 1996;
comparisons between groups across different outcome domains indi- Binder, 1993a, 1999) and supervision (Aveline, 1992; Haggerty &
cated no statistically significant differences in treatment effects at Hilsenroth, 2011) find only limited support from the current find-
posttreatment. The presence/absence of significant within-group dif- ings. This is perhaps unsurprising given that we might expect not
ferences in treatment effects between posttreatment and follow-up do, just the occurrence of recordings but also the type, quality, and
however, provide preliminary evidence that using research-specific perceived helpfulness of the review/supervision process received
procedures may in fact bring an advantage, particularly on measures to impact on treatment outcome. Research efforts should pay
of anxiety (⌬ds ranging from .56 to 1.40) and, to a lesser extent, attention to the longer-term effects of audio/video review both for
RESEARCH PROCEDURES META-ANALYSIS 287

treatment outcome as well as therapist training and development of An alternative interpretation of these results is that treatment
treatment competencies. effects present in psychodynamic psychotherapy studies that used
Furthermore, moderator analysis examining the magnitude of research-specific procedures translate largely only to improve-
difference in pre- to posttreatment outcome between those studies ments on measures of anxiety and personality functioning. By
that used recordings and those that did not, revealed a small effect statistical convention, small but consistently positive effects (⌬d ⫽
(d៮ ⫽ 0.36), favoring long-term treatment (⬎40 sessions). Closer .19 for use of manual; ⌬d ⫽ .19 for use of fidelity checks; ⌬d ⫽
inspection of the pooled mean effect size within studies of long- or .33 for use of audio/video recording) were present on personality
short-term treatment with or without audio/video recording functioning scores in follow-up. Results at 18-month and 8-year
showed that the larger treatment effects seen in studies not using follow-up, in one included study of manualized long-term psy-
recording was in fact driven by five studies that provided treat- chodynamic psychotherapy, specifically illustrate that continued
ment, with an average duration of approximately 3 years (145 improvement and wide-ranging changes in functioning can occur
sessions); d៮ ⫽ 1.40. The three studies of long-term psychodynamic at long-term outcome in a personality disordered sample (Bateman
psychotherapy that used audio/video recording, in contrast, pro- & Fonagy, 2001, 2008). More attention should be paid to the
vided on average only 59 sessions with a pooled posttreatment importance of efforts to pursue a “goal-orientated structure to
effect of d៮ ⫽ .95, comparable with short-term psychodynamic treatment” (Critchfield & Benjamin, 2006, p. 62) and therapist
psychotherapy (ⱕ40 sessions) outcomes (k ⫽ 38), with or without consistency (Livesley, 2007) for treating personality problems.
recording (d៮ ⬘s ranging from .92–.99). Thus, the observation of The magnitude of improvement in anxiety symptoms, however,
larger effects in psychodynamic psychotherapy without audio/ was more pronounced, both between pre- and posttreatment and at
video recording may be better accounted for by treatment dose follow-up assessment. Most notably, a very large statistically
rather than the impact of recording equipment. significant treatment effect (d៮ ⫽ 1.40, p ⫽ .004) was found
The lack of a significant association between outcome posttreat- indicating further improvement after therapy was completed in
ment and the use of either treatment manuals or fidelity checks is studies that checked fidelity. This finding, when taken alongside
consistent with findings from the common factors literature that the generally good evidence for the efficacy of manualized behav-
outcome variance due to treatment differences is minor (Lambert, ioral and cognitive– behavioral approaches with anxiety disorders,
1992; Wampold et al., 1997). A recent meta-analysis (k ⫽ 9) that may indicate that prioritizing the delivery of specific, concrete
included five overlapping studies analyzed here, also found no sig- techniques is important. This is consistent with symptoms of
nificant correlations between effects sizes and treatment integrity anxiety being potentially more tractable to strategies because they
procedures comparing psychodynamic psychotherapy with cognitive– are less likely to represent a disorder of the self (Roth & Fonagy,
behavioral therapy. Although effect sizes at follow-up were not ex- 2005).
amined, the magnitude of correlations at posttreatment did offer It remains to be seen whether these observations reflect chance
tentative evidence that the attention given to implementing procedural findings. Having not accounted for the possible moderating effects
interventions for monitoring fidelity may particularly benefit outcome of therapist experience and level of training, this may represent a
in psychodynamic psychotherapy (Leichsenring et al., 2011). The confound within the present study: we might predict larger effects
failure to replicate some of these posttreatment finding in the current and less variation between studies regardless of the use of research
study could be accounted for by a methodological difference between procedures in more experienced and well-trained therapists. Future
studies: here study differences were assessed based on a categorical research using larger sample sizes and greater power is necessary
distinction of the presence/absence of research procedures, which to address these issues more definitively.
ignores possible variation in the nature and quality of the procedures
used. However, a potentially new emerging finding from this study is Critical Analysis
evidence that continued therapeutic improvement occurring after psy-
chodynamic psychotherapy may be associated to the use of research- The results of this meta-analysis should be considered alongside
specific procedural factors. We were stuck to find that nine of a its limitations. First, this studies’ reliance on subgroup analyses to
possible 10 within-group analyses (90%), examining posttreatment to detect differences associated to different research-specific proce-
follow-up outcome change in studies according to the presence of dures cannot be used to prove causality: it is possible that differ-
treatment manuals or fidelity checks, were statistically significant ences in effect sizes may be attributed to differences between the
when the same was true in only two of 10 analyses (20%) for studies sets of studies. Second, although a large number of studies were
excluding these procedures. Between-groups statistical comparisons included in analyses, some controlled studies that may have met
were nonsignificant in all but one case; however, of the 10 analyses, the inclusion were missed because they were not included in past
two fell narrowly below the benchmark for a small effect (⌬d ⫽ .19) publications from which eligible studies were selected. Further-
and two were in the small/medium to large range (⌬d ’s ⫽ .33–1.40). more, the original searches were conducted at different times
As such, this offers further evidence that research procedural inter- (between 2005 and 2010) using different criteria so additional
ventions connected to assessment of how treatment is delivered, may studies may have since been published. Third, the possibility of
moderate outcome. These research procedures may also just be a publication bias stemming from a reliance on reviews of the
proxy variable for other influences that account for therapeutic change published outcome literature, which may fail to detect trials with
(Perepletchikova & Kazdin, 2005). We do, however, recognize that null findings, should be considered: publication bias analyses
the between-group analyses showed largely small effects and included conducted suggest this is, however, unlikely. Fourth, the quality of
a small number of studies, meaning the addition of new studies may included studies was variable (e.g., medication was allowed along-
change the results. We advise caution when interpreting these find- side psychotherapy in 23 studies). Although the results of suba-
ings, and further studies are required to confirm the results. nalyses to examine the moderating effect of use of treatment
288 TOWN ET AL.

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moderators is often low (Borenstien et al., 2009; Hedges & Pigott, sessions in the supervision and practice of dynamic psychotherapy.
British Journal of Psychotherapy, 8, 347–358. doi:10.1111/j.1752-
2004). Additional points for consideration on methodological
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