DHA 05-04-2018

(TOTAL 100 QUESTIONS AND 3 HOURS TO ATTEMPT,AS PER NEW PATTERN AND
60% PASSING CRITERIA)
1-Recommended calcium dose for geriatric

a-800mg

b-600mg

c-500mg

d-1200mg

2-desmopressin used in treatment of : nocturnal enuresis and diabetes Insipidus

3-after drug metabolism the drug become

a-polar (they wrote soluble)

b-nonpolar

c-active

d-nonactive

4-drug of choice for pseudomonal aeruginosa is: (pseudomonal infection)

a-meropenem

b-penicilln

c-imepeinm

5-long acting insulin is :

a-NPH

b-glargine
c-regular

6-routine medication for influenza is (STATEMENT CHANGED)

a-antibiotic

b-antiviral

c-influenza vaccine

7-acyclovir is used for herpes simplex

8-nevirapine is used for treatment of HIV (AIDS)

9-drug of choice for tape worms : (praziquantel and neclosamide)

a-Mebendazole

b-thiabendazole

c-neclosamide

10-influenza vaccine contraindicated in (0-6) months baby

11-drug should be used with precaution in asthma :b2 antagonist(they mentioned drug names
i.e propanolol)

12-prazosin is post synaptic alpha1 blocker (asked it class)

13-warfarin oral anticoagulant determined or calculated by

INR: international normalized ratio

14-which of the following decrease heart rate ?

a-phenylephrine

b- reserpine

c-metoprolol (beta1 blocker)

d-vasopressin

15-Early symptoms of aspirin poisoning are :

a-lethargy & fatigue

b-throbbing headache & dizziness

c-fluid retention hypotension

d-ringing in the ears & blurredvision

16-What first line agent may be considered for an obese type 2 according to Saudi national
fromualry(SNF) ?

a-glyburinid

b-insulin

c-metformin

e.repaglinid

17-which drug may used as anti-spasmodic

a-reserpine

b-amphetamine

c-baclofen

d-propranolo
18-Coal tar uses in (psoriasis)

19-which of these have interinsIc sympathomemtices effect:

a-labetlol

b-timlol

c-nadolol

d-pindolol

20-live attenuated vaccine:

a-measless,mumbs & rubella (MMR)

b-influenza

c-diphtheria

21-Pharmacy and therapeutic committee

a-storage of drug

b-adverse effect

c-expiration of drug

d-maintenance of formulary of drug

22-drug used to treat prostate cancer

a-flutamide

b-tamsulin

c-bethanecol

d-defranecin
23-estrogen antagonist and used first line in treatment of breast cancer(STATEMENT SLIGHTLY
CHANGED)

A-anastrazole

B –tamoxifen

24-which of the following conditions have non preventable adverse effect ?

a-allergy from amoxicillin with some one is known that hasn't adverse effect with any drug

b-tachy cardia with some forgot his dose of anti hypertensive drug and took 3pills

c-half dose of acetaminophen will cause fever

23-acetylcystiene is

A- Laxative

B- mucolytic

C- Skeletal muscle relaxant

24-The responsibility of pharmacist in hospital is

a- administration of drug

b- deal with patient

c- deal with drug interaction

d- notice effect of drug

25--which one used to trigeminal neuralgia

a-tegretol(Carbamazepine

b.propanolol c.ciprofloxacin
26-The most common disintegrator in compressed tablets is

a- Dextrose

b- Lactose

c- Starch

d- Potassium bitartrate

27-The aim in the management of uncomplicated hypertension

a-90\65

b-130\80

c-150\95

d-180\110

27-drugs have different crystal structures so different in

a-polymorphism

b-solubility

c-crystalitis

d-drug form

28-Amount of water in adult male 60%

29-A diabetic old patient with hyperlipidemia complains of erectile dysfunction so DOC

A) sildenafil

B) testosterone patch
30-which one of the following NSAID drug that most likely causes peptic ulcer

a- ibuprofen

b-indomethacin (also cause sodium and water retention)

c-diclofenac

d-naproxen

31-Sign of shock:

A. Hyper infusion

B. Hypoperfusion

C. Tachycardia

32-Cockcroft-Gault Equation is used for glomerular filtration and is indicted for

A.dialysis

B.stable chronic renal failure OR Bilateral renal failure & Bilateral= chronic

C.acute renal faliure

D.functional renal failure

33-month-old baby with a history of premature birth and chronic lung disease is admitted to
the pediatric intensive care unit with respiratory distress requiring intubation; fever; and a 3-
day history of cold-like symptoms. A nasal swab is positive for RSV. Which one of the following
is the best intervention?

A. Palivizumab.

B. Corticosteroids.

C. Cefuroxime.

D. Intravenous fluids and supportive care

34-CASE WOMAN Hypertension, diabetic and sensitive of sulph. Which is contraindicated with
sulpha

A-Glyburide

B- metformine

C-amidrone

D-enalopril

35-treatment for severe allergic asthma ? omalizumab

36-the recommended maximum adult daily dose of paracetamol (info: and for children:1g)

A-2500 mg

B- 3500 mg

C-4000mg( 4Gram)

37-.which antacid give cathartic effect as a side effect

A-Mg hydroxide

B-Ca sulfate

C-Ca hydroxide

38-anti coagulant taken oral

A . clopidogril

B.streptokinas

C.altepase

D.enoxaprin
39-procainaminde calss of drug in anti arrhythmia

a.class 1 B Antiarrythmic

b.class V

c.class 1a

40-latin term for 4 times a day

a.b.id

b.t.i.d

c.q.i.d

41.Q.I.D means

a.two times a day

b.three times a day

c.4 times a day

42-A Kidney failure patient with hyperkalemia which of the following should be used

A-insulin

B-thiazide diuretic

C-calcium gluconate ((or CA carbonate))

D-spironolactone

43-A non-smoker patient suffers from wheezing and chest tightness, what medication he
should use?(actual was lengthy statement but focus on wheezing and chronic)

A- B2 agonist
b- corticosteroids

C-omalizumab

44-Which of the following vaccine should be taken although you don’t need it:

a-Influenza vaccine

b-Mmr vaccine

c-Dap vaccine.

45-A diabetic patient takes metformin with glipizide and pioglitazone was added.Which test
should be done regularly?

A-Bun and Serum Creatinine

B. liver function.

46--A patient with peptic ulcer due to H.pylori and what is the best medication for him?

a.pantoprazole+clarithromycin+metronidazole(pantoprazole can be replaced with omeprazole)

b.antacid

c.metronidazole

47-A solution is made by dissolving 17.52 g of NaCl exactly 2000 ml.What is the molarity of this
solution?

a- 3.33

b- 0.15

c- 1.60

d-3.00 x 10 -4

e-1.6x10 -4
Answer :

Molarity=mole/volume (L)

1 Mole=molecular weight of subs. In 1 grams

No of Moles = wt / Mwt

So, molecular weight of NACL=23+34=57

So, Mole=17.52/57=0.307

So, Morality=0.307/2=0.153

48-How much water (in milliliters) should be added to 250 mL of 1:500 w/v solution of
benzalkonium chloride to make a 1:2000 w/v solution

A/0.4L

B/2L

C/0.2L

D/ 0.05L

Answer:

250/500 = 0.5

250/2000 = 0.125

0.5-0.125 = 0.375

49-A Patient weighting 80 Kg is supposed to receive a drug at a dose of 2mg/kg/day. What is

the dose that the patient should take for each day:

A. 80 mg ..... B. 160 mg C. 240 mg ..... D. 320 mg ..... E. 400 mg

Answer: 2*80=160
50-in clinic patient prescribed with a 500mg dose of aspirin , initial plasma conc is 100mg .. With
half life 6 hours calculate total body clearance ?

a.0.5 L/hr

b.5 L/hr

c 4.50 L/hr

Answer:

Vd = dose / initial conc = 500/ 100 = 5L.....T1-2 = 6 hr

Cl = 0.693 Vd / T1-2 = 0.693 × 5 / 6 = 0.5775 L/hr

51-priscription for a child contain Omeprazol syr. 10 mg/ml twice daily for a week .. you have
Omeprazol capsul 20 mg in your pharmacy, how many capsules are needed to prepare solution
with concantration 2 mg/ml ??(same concept but diff drug and values)

7 cap.

Answer:

10 mg/ml twice daily for a week = 140

20 _____1

140 _____ X

X=140/20=7

52-HOW can prepare 100 ml of 12% MgCl by taking?(this time they said 200ml so the ans was
24grm Mgcl dissolve in 100ml water)

a-12ml of MGCL dissolve in 100 ml water

b-12 gm of MGCL dissolve in 100 ml water

c-12ml of MGCL dissolve in 1000 ml water

d-90.5 ml of MGCL dissolve in 100 ml water

Note ; w/v = g/ml ..... ex ; 4% w/v means 4 gm in 100 ml

53-.Patient with prescription of Captopril 50 mg per tab with a dose of 100 mg daily for 4days
and you only have the 25 mg tab .. How many tablets you will dispense ?(same concept but diff
values)

16 Tab

Answer :

100 mg daily for 4 days = 400 mg

400/25 = 16 tab

54-a 9 mg/L solution , according ppm

a-9 ppm

b-0.009 ppm

c-0.000009 ppm

55-anti histamine act on which receptor

a.alpha 1

b.H1 receptor

c.H2 receptor

56-Which of the following is responsible for buffering

a-magnesium

b-chloride

c-bicarbonates

d-potassium
57-bisacodyl mechanism of action is

a. stimulating enteric nerves to cause colonic contractions

b.stool softner

58-which drug can not be taken in preganacy

a.captopril (plz confirm but I think acei are not recommended after 1st trimester)

b.aspirin

c.amoxil

59-lorazapam at a dose of 4 mg act as

a.sedative

b.laxative

c.hypnotic

60.You want to make 120mg/5ml paracetamol from 1.8 kg ,how much ml will you make out of
this material (cant remember exact statement)

a.2000

b.15000

c.51000

d.75000( what i calculated that time I guess was 75000 u can calculate again)

61-Mecahnism of action of Ca+ blocker

a.blocks ca channel and reducing O2 demand

b.positive ionotropic
62.which of the following groups of medicine increase risk of diabetes(exaggerated blood
glucose level)

a.statin

b.ca+ blocker

c.beta blocker

63. 0.8687 g cacl2 in 500 ml solvent, density of the solvent =0.95g\cm3.Find the molality
a- 0.0165 Molal
b- 0.0156 Molal
c- 0.0165 m
d- 0.0156 m
e- 0.0230 m

Molarity= no. of moles of solute/Liter of Solution

Stept1= determine no. of moles
Molecular weight of Cacl2=111
0.8687g/111g=0.007826 mole
Step2= determine mass of solvent in Kg
M=d*v, 500*0.95, 475g, 475g/1000g=0.475Kg
Cm3=ml
Stept3=determine molality
Step1/step2=0.007826/0.475=0.0165 molal

64-aspirin in children cause which of following

a.reye’s syndrome

b.ulcer

c.discoloration of teeth

65.29 yr man taking a drug(don’t remember name) and also takin a antidote but antidote is not
working.why?

a.anti dot dose was small

b.he had tolerance with antidote

66-pencillin test for intradermal ,which test is mandatory acc to SNF

a.skin scrath test

b.liver function

67-nicotinc drugs are labeled in pharmacy as

a.O

b.N

c.A

68-neonate suffer from cardio coaglopathy so vit k should be adminstrd by

a.iv

b.im

c.sc

69-which of the following has 1st pass metabolism

a.lorazepam/diazepam(plz confirm one of these)

b.warfarain

70-phenytoin dose for infants( I think there was a different drug but I don’t remember now
exactly but when I checked ans was same as mentioned)

a.0.5-1mg

b.1-2mg

c.3-5.mg
71. pt has lower limb and trunk pain used antipsychotic for 11 yr,what is the case

a.acute dystonia

b.tardive dystonia

c.tardive dyskinesia

72-if lactating mother has less milk production ,what are effects on infant

a.constipation

b.loss of appetie

c.diminshed weight gain

73.iproniazide given to a patient it increase secretion of nor adrenaline and other amines but its
one side effect it cause hypotension.what is the cause?(actual statement was bit changed)

a.increase excretion of nor adrenaline

b.its histaminic effect

c.it highly bound to plasma protein

74.drugs which are not yet registered and are waiting for comitee decision are called

a.non formulary drug

b.controlled drugs

c.norcotic drugs

75.drug will make bioavailability and stomach incompatibility if you break the pill into half

a.enteric coated pills

b.uncoated pills

c.sugar coated

76.which drug increase milk production by increasing prolactin level

a.estrogen

b.prolactin

c.metoclopramide and domperidone( both increase but there was one option)

77.perphenazine used as

a.nausea and vomiting

b diarrhea

c.constipation

78.how many times will measure drug serum concentration for therapeutic drug monitoring in
stable patient.

a.once daily

b.once during therapy

c.every month

79.biological materials should be kept on

a.0-2 C

b.2-8 C

these are all questions which I could remember and recall.please review the other files from
files section i.e
1(most imp)

Pearson new questions(most imp)

417 questions

And all in one.

Best of luck .remember me in your prayers.