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BENZODIAZEPINE

-anxiolitice, sedative, hipnotice, anticonvulsivante, miorelaxante


Actiune scurta(<6 ore)
-ALPRAZOLAM (anxiolitic, sedativ, antidepresiv)
-PRAZOLEX cpr. 0,25mg; 0,5mg; 1mg
-XANAX cpr. 0,25mg; 0,5mg; 1mg Doza initiala: 0,25mgx3/zi
-FRONTIN Doza maxima: 4mg/zi
-ALPRAZOLAM LPH
-ZOLAREM
-HELEX
Actiune intermediara(6-20 ore)
-BROMAZEPAM (anxiolitic)
-BROMAZEPAM LPH cpr. 1,5mg; 3mg Doza: 1,5-3mg pina la 6-18mg/zi
-CALMEPAM cpr. 1.5mg; 3mg (max. in spital 24-36mg)
-LEXOTAN cpr. 1,5mg: 3mg
-LORAZEPAM- anxiolitic (+++), sedative/hypnotic(+), anticonvulsivant
-efect antimaniacal superior Clonazepamului (Rivotril)
-ANXIAR cpr. 1mg Doza-anxietate 1-3mg de 2-3x/zi
-hipnotic: 2-4mg seara
-virstnici; 0,5-2mg divizate
-FLUNITRAZEPAM (sec-)- hypnotic/sedative; trat.de scurta durata
-ROHYPNOL cpr. 1mg Doza: 0.5-1mg/zi
-MEDAZEPAM- sedativ
-ANSILAN cpr. 10mg indicatii: sdr.psihoneurovegetativ, sdr.de abstinenta la
-RUDOTEL cpr. 10mg alcoolici, stari nevrotice anxioase cu irascibilitate
-MEDAZEPAM cpr.10mg Doza: 20-30mg/zi
CLORAZEPAS DIKALII (sec )- anxiolitic, anticonvulsivant, hipnogen
-TRANXENE cpr.5mg; 10mg Indicatii: sdr. nevrotice cu anxietate si fenomene
. somatice ( cardiace, digestive, respiratorii, sexuale )
Sdr.de abstinenta la alcoolici
Doza: 15-20mg/zi; intretinere: 10mg/zi
Actiune lunga(> 20h)
CLONAZEPAM-anxiolitic (+), sedative/hipnotic (+)
- RIVOTRIL cpr 0,5mg; 2mg
Ind.: agitatie maniacal, atac de panica, agorafobie, anxietate, TOC??, insomnia, psihoze
atipice, akatisie post N-L, depresie cu agitatie psihomotorie, nevralgie trigeminala
Doze: -agitatie psihomotorie (manie): 0,75mg-16mg/zi
-adjuvant in schizofrenie: 0,5-2mg/zi
-nevralgie trigeminala: 2-4mg/zi
DIAZEPAM-anxiolitic(+++); sedative/hypnotic(++); anticonvulsivant(+)
-cpr. 10mg; solutie injectabila 10mg/2ml; solutie rectala5mg/2,5ml; 10mg/2,5ml
-indicatii:- anxiolitic 10mg de 2-3x/zi
-sevraj alcoholic: 10ml de 3-4x/zi; 10ml I.m. 5-10mg la 3-4h
NITRAZEPAM, cpr. 2,5mg; 5mg
-indicatii: insomnia, anxietate, tensiune emotional, somn agitatsi neodihnitor
-doze; 5-10mg seara(0+1/2+1; 1/2x3/zi (5mg))
PRODUSE INRUDITE CU BENZODIAZEPINE
MIDAZOLAM-hipnotic, inductia anesteziei
DORMICUM cpr. 7,5mg; sol. Inj. 1mg/ml; 5mg/ml
Doze: 7,5-15mg
FULSED sol. Inj. 1mg/ml, 5mg/ml
MIDAZOLAM sol.inj. 1ml/ml; 2ml/ml; 5ml/ml
CLONAZEPAM-hipnotic
BERODORM cpr. 40mg doze: 40mg; virstnici 20mg (tratament de scurta durata)
ZOPICLONUM-anxiolitic, sedativ, miorelaxant, anticonvulsivant
ALS-ZOPICLON cpr 7,5mg indicatii: insomnii ocazionale, tranzitorii
IMOVANE cpr. 7,5mg doze: 7,5mg seara(citeva zile-> 2 saptamini),
Virstnici, insuf. Hepatica, insuf respiratorie-3,75mg
ZOLPIDEM-anxiolitic, sedative. hipnotic
HYPNOGEN cpr 10mg indicatii: insomnia ocazionale, tranzitorii, cronice
SANVAL cpr. 5mg; 10mg doze: 10mg seara
STILNOX cpr. 10mg virstnici, insuf. Hepatica- 5mg
ZOLPIDEM cpr. 10mg
LADINOX cpr. 10mg
HIDROXIZIN-derivat de difenilmetan (tranchilizant,antiemetic, miorelaxant)
HIDROXIZIN drajeuri 25mg
Ind.: agitatie anxioasa nevrotica, stari depresiv-anxioase, alcoholism, angioedem acut,
Adjuvant in dureri insotite de anxietate, greturi
Doze: 25mgx1-3/zi
MEPROBAMAT-tranchilizant, anticonvulsivant, miorelaxant
cpr. 400mg
ind.: anxietate, distimie, hipnogen, hiperexcitabilitate, tulburari vegetative
doze: 400-1200-2400mg/zi
BUSPIRONUM-anxiolitic selectiv, hipnotic, anticonvulsivant, fara efecte miorelaxante
STRESSIGAL cpr. 10mg
SPITOMIN cpr. 5mg; 10mg
Indicatii: sdr. Anxios, reducerea simptomelor premenstruale
Doze: 3x5mg/zi pina la maxim 60mg/zi

BARBITURICE
AMOBARBITAL-durata medie de actiune (aprox. 6h); sedativ, hipnotic
AMITAL 200 cpr. 200mg
AMOBARBITAL cpr. 100mg
doze: 25-50mg de1-3x/zi (sedativ)
100-200mg seara cu 1/2h inainte de culcare (hipnotic)
CICLOBARBITAL-durata scurta de actiune (2-3h), sedativ, hypnotic
CICLOBARBITAL SARE DE CALCIU cpr. 200mg
doze:-sedativ: 50-100mg de 1-2x/zi
-hipnotic; 200-400mg cu 1/2h inainte de culcare
EXIGAN-EXTRAVERAL (extract de valeriana 0,08g+fenobarbital 0,02g)
Ind: hiperexcitabilitate nervoasa, insomnia
Doze: 2-3 cpr./zi

TIMOSTABILIZATORI
CARBAMAZEPINA
CARBAMAZEPINA cpr.200mg
TIMONIL, TIMONIL retard cpr. 150mg, 300mg, 600mg; sirop pediatric 100mg/5ml
TAVER cpr.200mg
CARBASTIM cpr. 200mg
FINLEPSIN cpr. 200mg; cpr. Retard 200mg, 400mg
NEUROTOP cpr. 200mg; cpr. Retard 300mg, 600mg
TEGRETOL CR 200mg, 400mg
ind: epilepsie, manie, PTSD, nevralgie de trigemen, sdr. De abstinenta la alcool, cocaine, BZD
doze:-depresie 400-600mg/zi
-nevralgie trig. 2x100mg/zi pina la 1600mg/zi???
-psihoze ->1200mg/zi
-intretinere 3x200mg/zi
-alcoolism 800-1200mg/zi
OXACARBAZEPINA- ind in crize epileptic partiale +/- convulsii
TRILEPTAL cpr. 300mg, 600mg
doze 600->1200->2400mg/zi
(o sapt)
ACID VALPROIC-creste concentratia presinaptica a GABA:
Indicatii: epilepsie, manie doza: 750mg/zi in 2-3 prize, crestere gradate pina la 1000-2500mg/zi.
Doza maxima: 60mg/kg/zi
CONVULEX cpr 150mg, 300mg, 500mg. Sirop 50mg/ml
DEPAKINE cpr 200mg, 300mg, 500mg
DEPAKINE CHRONO cpr 300mg (2/3 valproat de Na+ 1/3 ac. valproic)
ORFIRIL LONG cpr. 1000mg, cpr 150mg, 300mg, 500mg
ORFIRIL cpr. 150mg, 300mg, cpr. retard 600mg; sirop 300mg/5ml flacon 250ml, minicomprimate cu
eliberare prelungita 500mg, 1000mg
PETILIN cpr. 200mg
LAMOTRIGINA- inhiba eliberarea glutamatului (neurotransmitator excitant)
Ind.: convulsii partiale si convulsii tonico-clonice generalizate: depresie bipolara, manie acuta
Doze: 2x50mg/zi-2 saptamini; intretinere 200-400mg/zi (2prize): asociere cu acid valproic: 50-100-
200mg/zi
PLEXXO cpr. 25mg, 50mg, 100mg
LAMICTAL cpr. 25mg, 50mg, 100mg; cpr. masticabile 2mg, 5mg, 25mg
LAMEPTIL cpr. 25mg, 50mg, 100mg
LAMOTRIGIN cpr. 25mg, 50mg, 100mg

ANTIDEPRESIVE
TRICICLICE: CLOMIPRAMINA , doze: 125-150mg
ANAFRANIL- activator, ind. in tulb. obsesive; dj. 10mg, 25mg
CLOMIPRAMIN dj. 25mg
DOXEPIN (sedative, anxiolitic), dj 25mg- antidepresiv cu componenta psihomotorie sedative
Ind: depresie cu anxietate si agitatie
Doze: 160-240mg/zi -> 320-480mg/zi; doza intretinere: 100-200mg/zi
IMIPRAMINA-ANTIDEPRIN dj. 25mg (50-200mg/zi); ind. In depresie+anxietate si AP
AMITRIPTILINA (bloc. NA si 5HT); cpr. 25mg, 50mg; doze: 75-100mg/zi seara
TETRACICLICE: MIANSERINA -sedativ, anxiolitic; cpr. 10mg, 30mg
-ind.: toate tipurile de depresie (componenta psihomotorie sedativa)
-doze: 30-40mg seara, virstnici max. 30mg/zi; toxicitate cardiaca, hTA
NONTRICICLICE: MAPROTILINA (sedative, anxiolitic)- AD cu component psiho-motorie stabilizatoare
-ind. depresie cu agitatie sau inhibitie psihomotorie moderata
MAPROTILIN dj. 25mg; doze: 3x25mg/zi sau 75mg/zi seara; intretinere 2x25mg/zi
LUDIOMIL cpr. 10mg, 25mg
SIPROTILIN cpr. 25mg
(indescifrabil) 50, cpr. 50mg

BENZODIAZEPINE
Actiuni: anxiolitice, sedative
Actiune scurta (<6h): ALPRAZOLAM-anxiolitic, sedativ, antidepresiv; PRAZOLEX (cpr. 0,25mg; 0,5mg;
1mg), XANAX (cpr. 0,25mg; 0,5mg; 1mg), FRONTIN, ALPRAZOLAM LPH, ZOLAREM, HELEX
-doza initiala: 0,25mgx3/zi; doza maxima: 4mg/zi

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