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I am a 10th grade student enrolled in the Gifted and Talented Program at Glenelg High
School in Howard County, Maryland. In this program each student gets the opportunity to
research a topic of their choice. During this year, I will be investigating enzymatic activity
as it pertains to a sickle cell hemoglobin structure in Malaria diseased cells in order to
determine a more efficient way to kill the protist in people without this genetic trait.
Specifically, I intend to study and research the interaction that occurs between signaling
molecules, cell receptors, and long/short term effects as it pertains to sickle cell. My goals
this year are to generate an extensive source list that will ultimately help me argue a thesis
related to this topic. I will also undertake a research project in which I will generate
primary data. To date, I have used my school’s electronic databases, as well as other print
and online sources, to locate information on my topic.
Thank you for your consideration of my request. Any information can be sent to the return
address above, to the attention of Leila Chawkat/Emmanuel Mekasha. However, if it is
more efficient, information can be emailed to mgiruye@aol.com. I hope to hear from you at
your earliest convenience. Of course, you can message whenever it is a convenience. Please
do not feel a necessity to answer by a deadline. Please and thank you for
Sincerely,
Emmanuel Mekasha