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B) change in the number of genes in a population over time A) descent with modification
C) survival of the fittest
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2) Which variable is likely to undergo the largest change in value
resulting from a mutation that introduces a new allele into a
population at a locus for which all individuals formerly had been
fully homozygous?
A) average heterozygosity
A) average heterozygosity
B) nucleotide variability
C) geographic variability
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3) Which statement about the beak size of finches on the island of Daphne back 3
Major during prolonged drought is true?
B) Each bird's survival was strongly influenced by the depth and strength B) Each bird's survival was strongly influenced
of its beak as the drought persisted. by the depth and strength of its beak as the
C) Each bird that survived the drought produced only offspring with drought persisted.
deeper, stronger beaks than seen in the previous generation.
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5) Rank the following one-base point mutations (from most likely to least5
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likely) with respect to their likelihood of affecting the structure of the
corresponding polypeptide.
A) 1, 2, 3, 4
B) 4, 3, 2, 1
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6) Genetic variation _____.
HIV's genome of RNA includes the code for reverse transcriptase (RT), frontan
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enzyme that acts early in infection to synthesize a DNA genome off of an
RNA template. The HIV genome also codes for protease (PR), an enzyme
that acts later in infection by cutting long viral polyproteins into smaller,
functional proteins. Both RT and PR represent potential targets for
antiretroviral drugs. Drugs called nucleoside analogs (NA) act against RT, D) using moderate doses of NA and two
whereas drugs called protease inhibitors (PI) act against PR. different PIs at the same time for several
7) Which of the following represents the treatment option most likely to months
avoid the evolution of drug-resistant HIV (assuming no drug interactions
or side effects)?
A) using a series of NAs, one at a time, and changed about once a week
HIV's genome of RNA includes the code for reverse transcriptase (RT), frontan
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enzyme that acts early in infection to synthesize a DNA genome off of an
RNA template. The HIV genome also codes for protease (PR), an enzyme
that acts later in infection by cutting long viral polyproteins into smaller,
functional proteins. Both RT and PR represent potential targets for
antiretroviral drugs. Drugs called nucleoside analogs (NA) act against RT,
whereas drugs called protease inhibitors (PI) act against PR.
D) One of the RNA molecules has experienced
gene duplication as the result of translocation.
8) Every HIV particle contains two RNA molecules. If two genes from one
RNA molecule become detached and then, as a unit, get attached to one
end of the other RNA molecule within a single HIV particle, which of
these is true?
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13) Suppose 64% of a remote mountain village can taste front 13 back 13
phenylthiocarbamide (PTC) and must, therefore, have at least one
copy of the dominant PTC taster allele. If this population conforms
to Hardy-Weinberg expectations for this gene, what percentage of
the population must be heterozygous for this trait?
A) 16% D) 48%
B) 32%
C) 40%
D) 48%
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14) For biologists studying a large flatworm population in the lab,
which Hardy-Weinberg condition is most difficult to meet?
A) no selection
D) no mutation
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A) no selection
D) no mutation
A) Yes.
B) No; there are more heterozygotes C) No; there are more homozygotes than
than expected. expected.
C) No; there are more homozygotes
than expected.
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17) If, on average, 46% of the loci in a species' gene pool are
heterozygous, then the average homozygosity of the species should
be _____.
A) 23%
B) 46%
C) 54%
C) 54%
D) 92%
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A) nucleotide variability
D) nucleotide variability and average
B) chromosome number heterozygosity
C) average heterozygosity
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19) Whenever diploid populations are in Hardy-Weinberg
equilibrium at a particular locus, _____.
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B) heterozygotes can come about in two ways B) heterozygotes can come about in two ways
C) the population is doubling in number
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B) heterozygotes can come about in two ways D) heterozygotes have two alleles
C) the population is doubling in number
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22) In a Hardy-Weinberg population with two alleles, A and a, that
are in equilibrium, the frequency of the allele a is 0.3. What is the
frequency of individuals that are homozygous for this allele?
A) 0.09
B) 0.49
A) 0.09
C) 0.9
D) 9.0
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23) In a Hardy-Weinberg population with two alleles, A and a, that
are in equilibrium, the frequency of allele a is 0.2. What is the
frequency of individuals that are heterozygous for this allele?
A) 0.020
B) 0.04
D) 0.32
C) 0.16
D) 0.32
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24) In a Hardy-Weinberg population with two alleles, A and a, that
are in equilibrium, the frequency of allele a is 0.1. What is the
frequency of individuals with AA genotype?
A) 0.20
B) 0.32
D) 0.81
C) 0.42
D) 0.81
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25) You sample a population of butterflies and find that 56% are
heterozygous at a particular locus. What should be the frequency of
the recessive allele in this population?
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26) In peas, a gene controls flower color such that R = purple and r
= white. In an isolated pea patch, there are 36 purple-flowering
plants and 64 white-flowering plants. Assuming Hardy-Weinberg
equilibrium, what is the value of q for this population?
A) 0.36
D) 0.80
B) 0.64
C) 0.75
D) 0.80
28) What is the estimated frequency of allele A in the gene pool? B) 0.50
A) 0.25
B) 0.50
C) 0.75
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29) What proportion of the population is probably heterozygous (Aa) for C) 0.50
this trait?
A) 0.05
B) 0.25
C) 0 50
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B) is more important in eukaryotes than in prokaryotes A) does little to change allele frequencies
C) happens in all populations
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A) a genetic bottleneck
D) the founder effect
B) sexual selection
C) habitat differentiation
34) Refer to the paragraph on dark-eyed junco birds. The UCSD campus
male junco population tails were on average 36% white whereas the tails
In 1983 a population of dark-eyed junco birds became establishedfront on the
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campus of the University of California, San Diego (UCSD), which is
located many miles from the junco's normal habitat in the mixed-
coniferous temperate forests in the mountains. Juncos have white outer tail
feathers that the males display during aggressive interactions and during
courtship displays. Males with more white in their tail are more likely to
win aggressive interactions, and females prefer to mate with males with
more white in their tails. Females have less white in their tails than do
A) natural selection
males, and display it less often. (Pamela J. Yeh. 2004. Rapid evolution of a
sexually selected trait following population establishment in a novel
habitat. Evolution 58[1]:166-74.)
35) Refer to the paragraph on dark-eyed junco birds. The UCSD campus
male junco population tails are about 36% white whereas the tails of
36) The Dunkers are a religious group that moved from Germany to 36
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Pennsylvania in the mid-1700s. They do not marry with members outside
their own immediate community. Today, the Dunkers are genetically
unique and differ in gene frequencies, at many loci, from all other
populations including those in their original homeland. Which of the
following likely explains the genetic uniqueness of this population?
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C) a founder event
D) a genetic bottleneck
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38) Which of the following is the most predictable outcome of
increased gene flow between two populations?
A) nonrandom mating
B) geographic isolation
D) gene flow
C) genetic drift
D) gene flow
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41) You are maintaining a small population of fruit flies in the laboratory
by transferring the flies to a new culture bottle after each generation. After
several generations, you notice that the viability of the flies has decreased
greatly. Recognizing that small population size is likely to be linked to
decreased viability, the best way to reverse this trend is to _____.
A) cross your flies with flies from another lab A) cross your flies with flies from another lab
B) reduce the number of flies that you transfer at each generation
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42) The inability of organisms to evolve anything that could be an
advantage reflects _____.
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43) Which of the following is a fitness trade-off (compromise)?
A) In some hornbill species, the male helps seal the female in a tree with
her nest until the young are ready to fledge.
B) Hummingbirds are the best pollinators of certain flowers, but bees are D) Turtle shells provide protection but are
the best pollinators for orchids. heavy and burdensome when moving.
C) The strong, thick beak of a woodpecker helps it find insects in trees.
D) Turtle shells provide protection but are heavy and burdensome when
moving.
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45) Examine the figure above. What
type of selection for body size appears
to be occurring in these marine iguanas?
A) directional selection
A) increase; directional
C) decrease; directional
B) increase; disruptive
C) decrease; directional
D) decrease; disruptive
47) Three-spined stickleback fish (Gasterosteus aculeatus) show front 47 back 47
substantial heritable variation in gill-raker length related to differences in
their diets. Longer gill rakers appear to function better for capturing open-
water prey, while shorter gill rakers function better for capturing shallow-
water prey. Which of the following types of selection is most likely to be
found in a large lake (open water in the middle and shallow water around
the sides) with a high density of these fish? C) disruptive selection
A) directional selection
B) stabilizing selection
C) disruptive selection
D) sexual selection
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48) A biologist doing a long-term study on a wild spider population
observes increased variation in silk thickness. Which of the
following could the spider population be experiencing?
A) directional selection
C) disruptive selection
B) stabilizing selection
C) disruptive selection
D) genetic drift
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49) In some jacana species, males take care of the eggs and young, and
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females compete among themselves for territories that contain one to
several males. Female jacanas are significantly larger than males. Which
of these statements would you predict to be true of this bird species?
A) frequency-dependent selection
B) evolutionary imbalance
51) The restriction enzymes of bacteria protect the bacteria from
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successful attack by bacteriophages, whose genomes can be degraded by
the restriction enzymes. The bacterial genomes are not vulnerable to these
restriction enzymes because bacterial DNA is methylated. This situation
selects for bacteriophages whose genomes are also methylated. As new
strains of resistant bacteriophages become more prevalent, this in turn D) Methylated and nonmethylated strains
selects for bacteria whose genomes are not methylated and whose should be maintained among both bacteria and
restriction enzymes instead degrade methylated DNA. Over the course of
evolutionary time, what should occur? bacteriophages, with ratios that vary over time.
A) Methylated DNA should become fixed in the gene pools of bacterial
species.
1 natural selection
2. microevolution
3. intrasexual selection C) 4, 2, 1, 5, 3
4. evolution
5. sexual selection
A) 4, 1, 2, 3, 5
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53) Adult male humans generally have deeper voices than do adultfront female
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humans, which is the direct result of higher levels of testosterone causing
growth of the larynx. If the fossil records of apes and humans alike show a
trend toward decreasing larynx size in adult females and increasing larynx
size in adult males, then _____.
A) sexual dimorphism was evolving over time in these species A) sexual dimorphism was evolving over time
B) intrasexual selection seems to have occurred in both species
in these species
C) stabilizing selection was occurring in these species concerning larynx
size
D) selection was acting more directly upon genotype than upon phenotype
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54) Most Swiss starlings produce four to five eggs in each clutch.
Starlings producing fewer or more than this have reduced fitness.
Which of the following terms best describes this situation?
A) directional selection
B) stabilizing selection
B) stabilizing selection
C) disruptive selection
D) sexual selection
55) When imbalances occur in the sex ratio of sexual species that
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have two sexes (that is, other than a 50:50 ratio), the members of
the minority sex often receive a greater proportion of care and
resources from parents than do the offspring of the majority sex.
This is most clearly an example of _____.
C) stabilizing selection
D) frequency-dependent selection
56) A proficient engineer can easily design skeletal structures that are56
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more functional than those currently found in the forelimbs of such diverse
mammals as horses, whales, and bats. The actual forelimbs of these
mammals do not seem to be optimally arranged because _____.
A) natural selection has not had sufficient time to create the optimal design D) natural selection is generally limited to
in each case, but will do so given enough time
modifying structures that were present in
B) in many cases, phenotype is determined by genotype and the previous generations and in previous species
environment
C) though we may not consider the fit between the current skeletal
arrangements and their functions excellent, we should not doubt that
natural selection ultimately produces the best design
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57) Anopheles mosquitoes, which carry
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the malaria parasite, cannot live above
elevations of 5900 feet. In addition,
oxygen availability decreases with
higher altitude. Consider a hypothetical
human population that is adapted to life
on the slopes of Mt. Kilimanjaro in
Tanzania, a country in equatorial
Africa. Mt. Kilimanjaro's base is about
2600 feet above sea level and its peak is
19,341 feet above sea level. If the
incidence of the sickle-cell allele in the
population is plotted against altitude
(f t b l l) hi h f th
58) If there is no gene flow, the front 58
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shifts to the left or to the right, and the
population size consequently increases
over successive generations, which of
the following is most likely occurring?
C) disruptive selection
D) genetic drift
59) In the United States, the parasite that causes malaria is not present, but
African-Americans whose ancestors were from equatorial Africa are
present. What should be happening to the sickle-cell allele in the United
States, and what should be happening to it in equatorial Africa?
D) directional selection; stabilizing selection
A) stabilizing selection; disruptive selection
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