Charcot–Marie–Tooth

disease ALSANGEDY
 Foot drop BULLETS
 Hammer toe
FOR PACES
 inverted FOR EASY PASSING PACES FROM
champagne bottle THR 1ST ATTEMPT
Dr. Ibrahim Alsangedy
 Weakness in the
MRCP-UK
hands and forearms MRCPE
 Loss of touch
sensation
 pes cavus
 pes planus
 Involuntary grinding
ALSANGEDY BULLETS FOR PACES

of teeth and
squinting
 Neuropathic pain
 Sensory and
proprioceptive
nerves in hands and
feet are damaged,
while unmyelinated
pain nerves are left
intact
Causes
 The most common cause of CMT
(70–80% of the cases) is the
duplication of a large region on
the short arm of chromosome
17 that includes the gene PMP22
 Some mutations affect the gene
MFN2
Diagnosis
 History & clinical examination
 Nerve conduction studies
 Biopsy of the nerve
 DNA testing
Prognosis
 The severity of symptoms
ALSANGEDY BULLETS FOR PACES varies widely even for the same
type of CMT.
isangedy@gmail.com
 Cases of monozygotic twins
00965 69691034 with varying levels of disease
Facebook page: - MRCP PACES severity have been reported.
from the 1st attempt
Management
the most important goal for patients
with CMT is to maintain movement,
muscle strength, and flexibility.
Therefore, a multidisciplinary team
approach with occupational therapy,
physical therapy, orthoptist,
podiatrist, and orthopedic surgeon
is recommended.