Escolar Documentos
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Cultura Documentos
Family Planning Methods – Natural From the DOH website, the RPRH core principles are:
• Periodic Abstinence (i.e., calendar) 1. Responsible Parenthood which means that each family
• Billings (i.e., cervical- mucus) has the right and duty to determine the desired number
• Basal Body Temperature of children they might have and when they might have
• Lactational Amenorrhea them. And beyond responsible parenthood is Responsible
•ISSUE: Basis for decision-making in Family Planning – Is it Parenting which is the proper upbringing and
legal? – Is it ethical? education of children so that they grow up to be upright,
productive and civic-minded citizens.
• Its Legislative History: 2. Respect for Life. The 1987 Constitution states that the
government protects the sanctity of life. Abortion is NOT
• Redundancy to the Magna Carta for Women 2009
a FP method:
• Demographic studies showing the unmet needs of women
3. Birth Spacing refers to interval between pregnancies
– House Bill 4244 in Jan 2011 by Cong. Edcel Lagman
(which is ideally 3 years). It enables women to recover
(Albay)
their health improves women's potential to be more
• Senate Bill 2685 in June 2011 by Sen. Pia Cayetano productive and to realize their personal aspirations and
• Passed December 19, 2012 to be implemented January allows more time to care for children and spouse/husband,
2013 – Implementation hampered by religious groups and;
• “TRO” issued by the Supreme Court (Sereno) 4. Informed Choice that is upholding and ensuring the rights
• PRRD’s SONA requesting to lift TRO in July 2017 of couples to determine the number and spacing of their
• EO No.12 to fully implement RPRH Act in November children according to their life's aspirations and reminding
2017 couples that planning size of their families have a direct
bearing on the quality of their children's and their own
Body: the RPRH Act of 2012 lives.
• Guiding Principles based on IRR:
1. The right of spouses to found a family in accordance with • Its Contents: Pertinent Definition of Terms
their religious convictions and the demands of responsible 1. Abortifacient refers to any drug or device that primarily
parenthood; induces abortion or the destruction of a fetus inside the
2. The right of children to assistance, including proper care mother’s womb or the prevention of the fertilized ovum to
and nutrition, and special protection from all forms of reach and be implanted in the mother’s womb upon
neglect, abuse, cruelty, exploitation, and other conditions determination of the Food and Drug Administration
prejudicial to their development; (FDA).
3. The right of the family to a family living wage and 2. Natural Family Planning (NFP) refers to a variety of
income; and modern methods used to plan or prevent pregnancy based
4. The right of families or family associations to participate on identifying the woman’s fertility cycle.
in the planning and implementation of policies and 3. Responsible parenthood (RP) refers to the will and ability
programs that affect them. of a parent to respond to the needs and aspirations of the
BIOTHETICS PRELIMINARY TOPICS (Compiled: dpgomez, RN) 2
family and children. It is likewise a shared responsibility • The Natural Law
between parents to determine and achieve the desired 1. Beneficence
number of children, spacing and timing of their children 2. Non-maleficence
according to their own family life aspirations, taking into 3. Justice
account psychological preparedness, health status, 4. Autonomy
sociocultural and economic concerns consistent with their • The Natural Law (Thomas Aquinas)
religious convictions. Ø The Nature of the Sexual Encounter
1. Unitive
Body: the RPRH Act of 2012 2. Procreative (openness to it)
Vision: Empowered men and women living healthy, productive 3. Under matrimony
and fulfilling lives and exercising the right to regulate their own § The arguments of the Catholic Church against Artificial
fertility through legally and acceptable family planning Family Planning
services. Body: Synthesis:
o Will the physician encourage family planning?
Mission: The DOH in partnership with LGUs, NGOs, the o What family planning method/s will the physician
private sectors and communities ensures the availability of FP recommend?
information and services to men and women who need them.
Ø IS IT LEGAL? What does the PH Law tell the physician?
Program Goals: To provide universal access to FP Ø IS IT ETHICAL? What does Natural Law say?
information, education and services whenever and wherever
these are needed. Conclusions
• Service Delivery Standards ü Legal aspects on Reproductive Health
§ LGUs to Ensure Provision of RPRH ü Ethical issues on Reproductive Health
§ Availability of Information and Services –
Informed Choice and Volunteerism Post-Lecture Assessment 1 of 2
§ Access to Family Planning A 38/M and 43/F couple, married for 5 years already, came
Ø Fertility Awareness to a private clinic; asking for a referral to a facility
Ø IPCC conducting in-vitro fertilization.
Ø Modern FP Methods What should the physician do?
Ø Infertility Services
Ø Referral Services
§ Access to FP Information and Services
§ Access of Minors to FP Services Post-Lecture Assessment 2 of 2
§ Care for Victim-Survivors of Gender-based Violence A 15/F student of a prominent Catholic university, only
child of a showbiz family, came to a private clinic bringing
• Service Delivery Standards a “positive” pregnancy test result.
ü Care for Victim-Survivors of Gender-based Violence • Crying, she eventually admits that she was drunk-raped
ü Sexual and Reproductive Health Programs for PWDs by a 39/M politician wo had a wife and 3 kids.
ü Responding to Unmet Needs and Gaps of Care • Her words included: “Ayaw ko ng gulo (pertaining to her
ü Provision of Life-saving Drugs in Maternal family, her school, his family, his political career).
Emergencies Kailangan mawala po itong bata.”
ü Policies on Administration of Life-Saving Drugs
ü Certification of Midwives and Nurses
ü Integrating Reproductive Health Care into the Health
Professional Curriculum
ü Maternal and Newborn Care in Crisis
BIOTHETICS PRELIMINARY TOPICS (Compiled: dpgomez, RN) 3
HUMAN REPRODUCTION AND GENETIC § Many benefits of Biotechnology and Biomedicine
ENGINEERING § By raising the quality of life, they have made it possible for
Poly T. Chua-Chan, MD us to take significant steps beyond what even our parents
and grandparents dreamed of.
Eugenics § BUT many bioethical problems are raised that
- Derived from the Greek word eugenesia meaning “to contemporary man has to resolve.
engender well”
§ Moral Issues of Genetic Engineering
- Positive Eugenics and Negative Eugenics
1. Positive Eugenics
Genetic Engineering
- Refers to the body of knowledge that aims to bring about - Gene: genea “breed, kind” and genesis “descent, origin”
the birth healthy offspring
- Genetics - the science that deals with the interaction of
- Aims to modify an individual’s hereditary characteristics the genes in producing similarities and differences
by reworking the environmental and social factors that between
individuals related by descent.
influence one’s development from the very moment of - Engineering - the art in the design, construction, and
conception à primarily hygienic operation
of rocks, bridges, buildings, etc.
- Improved living and working conditions
- The notion of genetic engineering is thus the introduction
- Better nutrition
of
human design (order or arrangement) into the
- Protection of mother during pregnancy, delivery and formation of new genetic combinations in order to produce
puerperium
the desired results.
- Fit lifestyle - Strictly speaking, GE means direct intervention in the
2. Negative Eugenics
genetic make-up of a living being, the replacement of
- Aims to check the conception of defective offspring and genes or the addition of new genes to the genetic ‘code’
the consequent transmission of infectious diseases or or ‘blueprint’ of an organism.
hereditary defects
- “Genetic manipulation”
- Special focus – disorders that are strictly hereditary - In other words, GE involves the whole process of altering
(albinism, alkaptonuria, Duchene’s Infantile Muscular genes,
the building blocks of life, in order to achieve
Dystrophy, Pseudo- hypertrophic dystrophy, neurosis, either a radically,
or a completely new, human being.
manic-depressive psychosis, schizophrenia, and epilepsy) - According to its advocates, GE is more human than the
biological process, insofar as it is well-planned and
Ethical Standpoint
systematically organized.
- Positive Eugenics – LICIT
- The biological process is left to chance, accident, and to
- Negative Eugenics: Prohibition of marriage, Sterilization the
blind forces of nature; whereas GE is willed and
& Abortion
scientifically designed by man for therapeutic and eugenic
Chromosomes, DNA, and Genes
reasons.
§ Every living being is composed of cells.
§ The nucleus of a single cell contains chromosomes.
TYPES OF GENETIC INTERVENTION
§ Every human being usually has 23 pairs of 46 single Therapeutic or Constructive or Creative
chromosomes
Corrective
§ A sperm and an ovum has 23 chromosomes each. Their - To repair defects - To develop new
fusion
in fertilization results in a zygote with 46 that produce certain characteristics in
illnesses the organism by
chromosomes.
- To improve the altering the
§ Of the 46 chromosomes, 44 are “carriers of character”
human phenotype subject’s hereditary
and 2
determine an individual’s sex. genetic content
§ Genes are made of DNA, the hereditary substance of living
cells.
Genetic Engineering Includes:
§ DNA technologists have developed a set of techniques that
v Genetic testing
make it possible to cut the long, threadlike molecules of v Genetic screening
DNA into pieces with the aid of certain enzymes, to v In vitro fertilization (IVF)
recombine the resulting segments of DNA with the DNA
v Cloning
of a suitable vector or carrier, and to reinsert the
v Sex selection
recombinant into an appropriate host cell to propagate and
v Organ transplant
possibly to function.
§ Thus the crux of recombinant DNA technology lies in the v Prenatal diagnosis
ability of the technologist to manipulate, splice, slice, and v Genetic control
replace the basic structural compounds of DNA and their v Embryo transfer
direct genetic change.
v Sperm and zygote banking
§ This is why Genetic Engineering is often called human v Surrogacy
intervention in the biological processes.
BIOTHETICS PRELIMINARY TOPICS (Compiled: dpgomez, RN) 4
Genetic Testing
outside the mother’s womb (unless such experimentation is
directly therapeutic)
Ø Biochemical studies or chromosomal analysis for
purposes of detecting genetically-caused diseases 5. To use human embryos or fetuses as the object or
Ø Such testing is currently employed to detect the carriers instrument of experimentation
of recessive disorders - Crime against their dignity
Ø e.g. Tay-Sach’s disease which leads to the gradual
debilitation and death of afflicted infants before the age - Human beings having a right to the same respect that is
of five.
due to the child already born and to every human person
Ø In the medical context, GT may be utilized for eugenic
purposes. Individuals who may be found to be “carriers” Genetic Screening
of recessive conditions or any genetically-related a. This procedure goes hand-in-hand with genetic
disorders may opt for sterilization or other forms of testing.
contraception in order to prevent the transmission of their b. Its main purpose is to screen, choose or select (a.k.a
genes and the birth of children with recessive disorders. genetic selection) the genes for proper detection of
Ø In this light, the wisdom of undergoing medical any genetic disease
and other chromosomal
examination for chromosomal analysis before marriage activities/malformations.
is highly recommended, especially for suspected carriers c. Individuals who are clinically well can be screened
of genetically- related diseases. to determine whether they are carriers of recessive
defective genes of certain genetic diseases (e.g. cystic
Prenatal Diagnosis
fibrosis,
hemophilia, sickle cell anemia, PKU)
d. Should both parents be found to be carriers of a
1. Amniocentesis – malformation or deformity of the fetus
specific
defective gene, there is a one-in-four chance
in utero can be detected as early as 5th month or 16th
that their children
will have the disease.
week of pregnancy, onwards.
e. Geneticists estimate that every individual carries from
A sample of amniotic fluid is extracted from the sac that
4-8
defective genes of some kind.
However, since
surrounds the fetus. This fluid, containing fetal cells, is
individuals usually have different kinds of bad genes,
subjected to laboratory chromosomal analysis wherein
the chance of procreating children with a genetic
genetic disorders can be detected
disorder is quite small. Nevertheless, it does happen.
2. Fetoscope - used to visualize various parts of the fetus,
So, it is a worthy human goal to prevent such disease
thereby detecting anatomical abnormalities in the
from occurring.
developing fetus.
Other techniques for drawing samples
f. Advocates of mass genetic screening are trying to
of fetal blood from the placenta have also been tested.
achieve this goal. In the medical context, genetic
screening can be used to obtain information for the
In the medical context, if the diagnosis reveals that the fetus
treatment of genetic disorders and to help prospective
is afflicted with any inborn error of metabolism, chromosomal
parents make responsible decisions concerning child-
abnormalities and variants, and polygenic conditions (e.g.
bearing.
spina bifida, anencephaly) the parents may use these data to
g. What justifies mass genetic screening is the purpose
decide whether or not to abort the fetus.
of obtaining information that can lead to the
3. If Prenatal Diagnosis is directed towards its safeguarding prevention of procreating abnormal children.
or healing as an individual - Counseling
h. It is argued that one has a moral duty NOT to cause
- Prepare the expectant parents of a special child suffering and/or injury to others by his actions, even
4. If done with the thought of possibly inducing an abortion if the harmful effects of such action will happen
- Malformation of a hereditary illness = death sentence
subsequently at a later time (e.g. the birth of
- Violation of the unborn child’s right-to-life
malformed babies)
- An abuse of the prior rights and duties of the spouses
BIOTHETICS PRELIMINARY TOPICS (Compiled: dpgomez, RN) 5
REMEMBER: Ethical Standpoint
- Consent of the parents for the procedure 1. Its manipulative, artificial action threatens to convert the
- Adequately informed that the methods employed human act of procreation into a mere technique devoid of
safeguard the life and integrity of the embryo and interpersonal relations
the mother. 2. “Improper” artificial insemination – dilatation of the
- Without subjecting them to disproportionate risks uterine cervix and the collection of semen found in the
vaginal recess and its reintroduction into the uterus so
that sexual union can result in pregnancy.
ETHICAL STANDPOINT: 3. Morally acceptable: If the technical means facilitate the
- Interventions to the human embryo are: conjugal act or help it to reach its natural objectives
LICIT NO LICIT Embryo Transfer (ET)
(ILLICIT) • ET Process:
1. Respect the life and 1. Destruction of the Ø By laparoscopy, an ovum is removed from the woman’s
integrity of the human embryo ovary
human embryo 2. Abortion
Ø Fertilized in vitro with the husband’s spermatozoaà
2. Do not expose the 3. Non-therapeutic Ø Embryo is cultured and then “transferred” to the uterine
mutation of the cavity for burrowing
embryo to dis-
Ø ET is related to ovum donor treatment– “removing an
proportionate risks. genetic code
ovum from a female donor, fertilizing it in vitro with a
3. Aims to cure it husband’s semen, and returning it to his wife, whose eggs
4. To improve its health are either defective, genetically abnormal, damaged by
and chances of disease, or absent”
Ø Male counterpart – Artificial insemination by donor
survival
(AID) Transcervical Balloon Tuboplasty (TBT)
Ø A new technique to clear blocked fallopian tubes
• Easier
and cheaper than IVF and ET
Ø Effective alternative for infertile women who want to
Genetic Intervention
become pregnant without surgery
Ø Use a tiny balloon to clear obstructions in the oviduct
- Genetic intervention, genetic control, genetic therapy,
genetic surgery, gene-splicing TBT Process:
- By these techniques, can now “intervene” in biological - Thread a series of three tubes called catheters through the
processes cervix and uterus and then into the portion of the fallopian
tube closest to the uterus
- Can now “control” bad or defective gene that will most
- When the third catheter reaches the blockage, a balloon at
likely produce deformed or retarded children the end is inflated to stretch the fallopian tube and dislodge
- Can “cure” (therapy), “slice” (surgery), “splice” the obstruction
(recombine) and “repair” and “redesign” (engineering) - Outpatient procedure under local anesthesia
- Recombinant DNA technique
- Might lead to the - Can go home within an hour
- Cheaper and less traumatic than surgery
understanding and control of the molecular processes
- Almost fool-proof
Surrogate Motherhood (SM)
involved in such diseases as cancer, diabetes, and
- “Surrogate” means substitute, Latin “surrogatus”
hemophilia.
- Might prevent certain birth defects like meaning “in place of another”
Spina Bifida
- Might pave for the development of new - Surrogacy is a biomedical technique whereby a fertilized
breeds of plants that are able to utilize nitrogen from the air ovum is implanted into the uterus of another woman who
and thus require no fertilizer
will carry the baby to term either as a favor or for a fee.
- Modified bacteria may be used as chemical factories to - Financial arrangement – “womb for hire”, “rent a womb”
or “uterus for rent” business
produce biological materials of medical importance– e.g.
- In such cases, a woman who can produce normal ova, but
insulin and other drugs that are very costly to synthesize whose health would be endangered by pregnancy, can have
chemically her ovum fertilized by her husband’s semen either in vitro
or in vivo and after three to five days of growth the embryo
Artificial Fertilization could be transferred to the uterus of a healthy woman who,
Artificial Insemination either out of friendship or for payment, would carry it to
a) Homologous (spermatocyte comes from husband) term.
b) Heterologous (spermatocyte comes from a donor other - After delivery, per agreement, she would give the baby to
than the husband)
the couple who are the genetic parents of the child.
- For the most part, surrogacy has fulfilled the dreams of
parenthood for infertile persons.
BIOTHETICS PRELIMINARY TOPICS (Compiled: dpgomez, RN) 6
- But in some 5 to 10 % of such cases, the process ends in - Technically known as “cryo-preservation”
legal wranglings and heartbreak for one or both sides.
Surrogacy
Sperm Banking Justifications:
- Contrary to the unity of marriage and to the dignity of the 1) To preserve the “seeds” of endangered animal species
procreation of the human person among the lower animals;
- Morally illicit: If the procedure were to replace conjugal 2) To overcome infertility among humans (e.g. AI purposes);
act 3) To serve as “fertility insurance” for men who wish to
undergo vasectomy, while hoping to retain their fertility
for
In Vitro Fertilization (IVF) future use;
- Fertilization in vitro means fertilization “within a glass” 4) To use sperm deposits for research on genetic diseases
and
“laboratory fertilization”, “test-tube fertilization”
reproductive processes;
- Performed in a petri dish or test tube
5) To further studies about sex selection for eugenic reasons
- Conception outside the womb by artificial means,
Procreation without sex
& “Baby making without love
Zygote Banking
making”
- Cryopreservation of fertilized eggs
ZB Process:
IVF Process:
Ø By laparoscopy or laparotomy, oocytes are first extracted
Ø Using laparoscopy, maturing ova are extracted from
from the female ovary à The eggs are then fertilized by
female’s ovary à The ovum is then placed in a petri dish
sperm in vitro
(test tube), where it is fertilized by the husband’s semen
à After several days of growth in the test tube, the Ø Frozen at a low temperature
fertilized ovum or embryo is implanted in the wife’s Ø Frozen zygotes can then be withdrawn from the banks to
uterus à
The embryo burrows itself in the be implanted into the female uterus for routine gestation
and birth
endometrium.
A normal pregnancy can be carried to
term
Sperm and Zygote Banking (SZB)
Ø In the medical context, the IVF technique is done to
Ø Women who shun sexual relations with men (or do not
overcome female sterility due to obstruction of the
want to have husbands due to some traumatic experiences
fallopian tubes, which prevent the ovum from passing
in a broken marriage) but who want to conceive children
through the oviduct where it meets the sperm and then
through artificial insemination or embryo transfer usually
descends to the uterus for
burrowing.
avail themselves of the services of zygote banking and/or
Ø Surgical removal of the blockage is very difficult, or in
sperm banking.
most
cases, impossible.
Ø Patients would be able to select gender, race, and hair and
Ø Surgical extraction of ova from the ovaries, however, is
eye color of their offspring.
possible– hence, in vitro fertilization takes place.
Ø In England, servicing a growing number of women who
Ø No person outside the marriage is involved in the product
are seeking a “virgin birth” for their children
of fertilization because the generative cells come from the
Ø A patient, who typically has never had sex with a male,
husband and wife themselves.
is to receive twice-monthly insemination using donor
semen from a sperm bank until she becomes pregnant.
Other Significant Goals:
1. To observe and evaluate the process of fertilization in
SZB Justifications:
vitro, which is not possible in the case of fertilization in
1) A couple in which both partners are carriers of
utero;
complementary recessive genes could prevent the birth of a
2. To test the effectiveness of anti-fertility agents;
potentially afflicted child by substituting their sperm or egg
3. To evaluate the fertilization of the ova of patients with with those of a donor known to be free of such genes or simply
infertility problems
requesting a defective-free zygote
4. To assess the structural and biochemical normality of the 2) Superior human beings could be bred by mating eggs and
conceptus in patients who have had repeated sperm from donors possessing certain desirable traits; frozen
spontaneous abortions;
sperm and eggs would permit a high degree pf selectivity
5. To better understand the mechanisms needed for genetic among donors to assure such preferred matching
studies;
3) This preferential breeding of so-called superior individuals
6. To advance understanding of normal and abnormal cell should be done to improve the genetic stock of the human race;
growth and differentiation;
and
7. To increase knowledge that is useful in contraceptive 4) Individuals or sperm donors who are found to be carriers of
technology and in alleviation of genetic disorders and defective genes or genetically-related diseases should be
other deformities
advised to undergo vasectomy, therapeutic or contraceptive
sterilization.
Sperm Banking
- Freezing and preservation of sperm at low temperature
Sex Selection
BIOTHETICS PRELIMINARY TOPICS (Compiled: dpgomez, RN) 7
Ø Sex control, sex determination, sex predetermination and - A stem cell is a cell whose job in the body is not yet
sex pre-selection determined
Ø Refers to means by which the sex of an offspring can be - Every single cell in the body “stems” from this type of cell
chosen • Natural strategies (have genetic and
physiological bases) - Stem cells wait for signals to tell them what to become
Ø Dr. Abelina Barrion:
- When stem cells receive signals, it begins to differentiate
- Consulting the Chinese calendar
or
gradually change into its destined cell type.
- Monitoring one’s menstrual cycle - The signal tells the stem cell to turn on certain genes and
- Monitoring female orgasm
make
new proteins.
- Vaginal rinsing
- These new proteins will make the stem cell to look and act
- Timing semen ejaculation like
the cell type it is supposed to become.
- By the time it finishes differentiating, it will have stopped
Sex Selection: PRECONCEPTION METHOD
dividing too.
Ø Preconception research aims to provide a means whereby - The differentiation process helps cells specialize so they
one could control which type of sperm fertilized the
can do
their different jobs.
ovum. - One proposed approach: androsperm are less
dense and smaller than gynosperm, hence a diaphragm
Types of Stem Cells:
could be inserted in the vagina to filter out the
1. Early Embryonic stem cells
gynosperm, thereby allowing only the androsperm to
- The first step in human development occurs when
reach the egg in the oviduct.
newly fertilized egg or zygote begins to divide,
Ø A different method would require a special treatment of
producing a group of cells called embryo.
male semen followed by artificial insemination. By
TOTIPOTENT – (total potential) stem cell that can
means of one or a combination of four treatments –
become ANY kind of cell in the body. Toti – “whole”
centrifugation, electrophoresis, agglutination, or albumin
or “total”
isolation, a medical expert would separate the
2. Blastocyst Embryonic stem cells
androsperm and gynosperm, then artificially inseminate
- Seven days after fertilization, the embryo forms a
the female with the preferred sperm.
hollow ball-like structure called a Blastocyst.
Sex Selection: POSTCONCEPTION METHOD - Embryos in the blastocyst stage contain 2 types of
ü One method involves the removal of the blastocyst cells:
i. Embryonic stem cells form the inner cell
from
the mother, determining its sex and then re-
mass à fetus
implanting it
in the uterus if it is of the desired sex.
ii. Trophoblast cells à placenta
ü Another method is based on amniocentesis as early as PLURIPOTENT (more potential), having the ability to
12th week of pregnancy or during 1st trimester (84
become ALMOST ANY kind of cell in the body.
Pluri –
days
after conception).
“more” or “most”
ü If it is found out hat the sex of the fetus is contrary to 3. Fetal stem cells
what
the parents prefer, they have the option to abort. - After the eight week of development, the embryo is
Sex Selection Justifications:
referred to as the fetus. By this time, it has developed
1) Primary justification: control of diseases (sex-linked and
into a human-like form.
sex-influenced – hemophilia, typically affecting males who - Responsible for the initial development of all
inherit it through the mother; Parkinson’s Disease)
tissues
before birth.
2) Promotion of happiness for the parents who would be - PLURIPOTENT
happier because an offspring would be the preferred sex;
4. Umbilical Cord stem cells
3) And the offspring would be happier because they would
not - Blood from the umbilical cord contains stem cells
feel they were of an “unwanted sex”
that
are genetically identical to the newborn child.
4) Secondary justification– contemplated reduction of - MULTIPOTENT (much potential) they can
birthrate, it would reduce the total number of births because
differentiate into only a limited range of cell types.
parents would not have to beget additional children if only to - Multi – “many” or “much”
have one or more of a particular sex preference
5. Adult stem cells
5) Third justification- accumulation of scientific knowledge - “Adult” is misleading, because infants and children
about human reproduction. In the absence of any negative
also have them.
consequences of such research, it is maintained that further - These stem cells reside in already-developed tissues,
knowledge of sex selection is justifiable.
directing their growth and maintenance throughout
6) Fourth justification – preventive of abortion. Many
life.
parents who prefer a son to a daughter, resort to aborting the
- MULTIPOTENT
fetus if it is found to be female through the processes of
- Common locations: nerve, blood, muscle, skin, bones
amniocentesis and abdominal ultrasound.
6. Induced Pluripotent stem cells
Stem Cell
BIOTHETICS PRELIMINARY TOPICS (Compiled: dpgomez, RN) 8
Advantages and Favorable Consequences of Genetic harm and to seek the good for one’s offspring.
Engineering - Example: An individual who is a carrier of a certain
genetically- linked disease, has the moral duty to
Medical interventions and manipulative reproduction would prevent the birth of a child afflicted with that kind of
heighten the intelligence quotient of the race and provide ailment or deformity.
solutions to some solutions to some particularly difficult and - When, upon discovering that one is a carrier of
intractable human problems. - Joseph Fletcher defective genes one still does not take steps to prevent
the conception of babies, one is not only remiss of
Fletcher’s View one’s moral duty, but in fact would seem to be
intentionally conceiving malformed children.
- Man is a marker and a selector and a designer, and the more
- By all indications, such an act of remissness or
rationally contrived and deliberate any thing is, the more
omission seems to be inhuman and unchristian, for in
human it is.
that case one has failed to perform his moral concern
- Moreover, laboratory reproduction is radically human
for the well-being of the other.
compared to conception by ordinary hetero-sexual
- Would you like every Filipino mother to beget a
intercourse.
severely deformed child?
- It is willed, chosen, purposed and controlled, and surely
- If not, then as a mother who has been found to be a
these are among the traits that distinguish homo sapiens
carrier of defective genes, it is your moral duty to
from others
in the animal genus.
prevent the conception of a gravely abnormal fetus
or child. Such a moral decision would be in keeping
Questions to be Answered
with the spirit of the categorical imperative.
- Would genetic engineering produce the most benefits,
comfort, and happiness at the least cost of pain or
unhappiness?
- Would there be a greater balance of happiness and progress
over unhappiness and unprogress for all individuals
affected?
Utilitarian Ethics
BIOTHETICS PRELIMINARY TOPICS (Compiled: dpgomez, RN) 10
- Defined as the involuntary loss of the products of Ø Fetal brain begins to form
conception prior to 20 weeks of gestation. Ø Brain waves produced by 6 weeks
Incidence:
- 15% of all confirmed pregnancy ABORTION STATITICS BY WEEKS OF GESTATION
- 80% occur in 1st trimester Weeks of Gestation Aboriton (% of Total)
- Most common cause: Chromosomal abnormality <6 22 ß
- Not normally viewed as a type of abortion. 7 18
ABORTION ARGUMENTS 8 18
Ø Scientific considerations >8 42
Human Embryology 101
Therefore, 78% of abortions occur after fetal waves have
When does human life begin?
begun
FETUS – JUST A “BLOB OF TISSUE”?
Ø “I opened the sock up and I put it on the towel and there
Moral Issues
were parts in there of a person. I’d taken anatomy; I was
- When does a person begin to exist?
a medical student. I knew what I was looking at. There
Religious Issues
was a little scapula and there was an arm, and I saw some
- Teachings of the Catholic Church ribs and a chest, and I saw a little tiny head, and I saw a
piece of a leg, and I saw a tiny hand. ... I checked it out
SCIENTIFIC ARGUMENTS and there were two arms and two legs and one head, etc.,
• When does human life begin? •Medical textbooks •Statements and I turned and said, I guess you got it all ... It was pretty
of doctors awful that first time... it was like somebody put a hot
• When does abortion occur? poker into me.” (Dr. David Brewer, in training)
• “Products of conception” – just a “blob of tissue” Ø “I watched as the contents of the woman’s womb came
through a suctioning device and into a stainless-steel pail
MEDICAL EMBRYOLOGY TEXTBOOKS sitting at his feet. I stepped back and wiped the
perspiration from my brow. “This is kind of gruesome,”
1. The Developing Human: Clinically Oriented I said.... The doctor said, “At this point in a pregnancy,
Embryology the products of conception aren’t much.” I stepped
- "Zygote: this cell results from the union of an oocyte forward and peered into the pail. This time I broke out in
and a sperm. A zygote is the beginning of a new human a cold sweat. I backed up and leaned against the wall, my
being (i.e., an embryo). Human development begins at eyes closed. Dear Jesus! I thought. I just saw someone
fertilization... This highly specialized, totipotent cell murdered! And I just stood and watched! (Nurse Don
marks the beginning of each of us as a unique Haines, in training)
individual.” Ø “I had a quick sonogram and then received a shot of
2. Essentials of Human Embryology methrotrexate. After the shot, I came home... I went to
- “In this text, we begin our description of the bed that evening around 9 p.m... I continued contracting
developing human with the formation and and bleeding most of the night. Around three in the
differentiation of the male and female sex cells or morning, I went to the bathroom. When I stood up, I
gametes, which will unite at fertilization to initiate the noticed that the pain and the pressure was not from clots,
embryonic development of a new individual.” but from passing the placenta. When I looked in the
3. Human Embryology & Teratology commode, I saw laying in the center of the placenta my
- “Fertilization is an important landmark because, under baby. I saw the baby's perfectly formed hands, the little
ordinary circumstances, a new, genetically distinct fingers. I remember the scream that came from my
human organism is thereby formed...” mouth... [from a 7 week abortion] (Char, “I used to be
Pro- choice...But...”)
WHAT DO MEDICAL DOCTORS SAY?
Ø Dr. Alfred Bongioanni (University of Pennsylvania): “I SCIENTIFIC CONCLUSIONS
have learned from my earliest medical education that
Ø Human life begins at conception
human life begins at the time of conception.”
Ø Human development proceeds rapidly (all organs and
Ø Dr. Jerome LeJeune (University of Descartes): “after
systems are in place by week 8)
fertilization has taken place a new human being has come
Ø Abortion stops a beating heart
into being.”
Ø Most abortions occur after the fetus exhibits measurable
Ø Dr. Hymie Gordon (Mayo Clinic): “By all criteria of
brain waves
modern molecular biology, life is present from the
MORAL ARGUMENTS
moment of conception.”
Ø Dr. Micheline Matthews-Roth (Harvard University Ø “Benefit” to women
Medical School): “It is scientifically correct to say that an Ø “Benefit to child (every child “wanted”)
individual human life begins at conception” Ø “Right” to control their own body
Ø Population control
HUMAN EMBRYOLOGY 101 Ø Fetus is not a person – personality argument “BENEFIT”
Ø Fetal heart begins
to form 18 days after conception TO WOMEN
Ø Measurable heart beat 21-24 days after conception
BIOTHETICS PRELIMINARY TOPICS (Compiled: dpgomez, RN) 11
Ø Prevention of deaths from “coat hanger” or “back alley” 3. Who makes the definition?
abortions 4. Society has excluded certain humans from
Ø Cases of rape or incest, fetal abnormalities or threats to personhood before (e.g., African slaves, Chinese,
mother’s life or health etc.) Should we make a new list of human non-
Ø Abortion alleviates economic and social problems. persons?
Ø Ø The lack of certain personality traits would remove from
THE “HARD” CASES personhood:
Abortion must be available for: - Those who are in a coma
- cases of rape or incest Represent only 1% of all cases - Elderly with degenerative disorders (Alzheimer's, etc.)
- cases of fetal abnormalities Represent only 1% of all - Mentally deficient
cases - Genetic
- mother’s health is at risk Represents only 3% of all - Neurological disease
cases - Mental illness
Ø Is it okay to consider these human beings as non-
ABORTION ALLEVIATES ECONOMIC AND SOCIAL persons?
PROBLEMS
1. Pregnancy subjugates women, interferes with career DEFINITION OF PERSONHOOD
and educational choices
v One who is consciously performing personal acts –
2. For most women, pregnancy does not interfere with eliminates those who are sleeping
the ability to work or attend school, except after birth v One with a present capacity to perform personal acts –
eliminates those who are in a coma
3. Laws prevent employers from firing or discriminating v One who has a history of performing personal acts –
against pregnant women
eliminates one who was in a coma from birth, but wakes
4. Women are not forced to keep their children. Adoption up
is always an option
v One with a future capacity for performing personal acts –
5. The existence of social problems is not justification for makes those who are dying as non-persons
another evil
IMPLICATIONS OF FUNCTIONALLY-DEFINED
EVERY CHILD SHOULD BE WANTED PERSONHOOD
1. Being wanted is not a condition of the child, but of the ü Newborns lack the ability to perform personal
adult functions – in fact, newborn humans are less capable
2. Is it fair to kill a child because of the attitude of an physically and mentally than virtually all other
adult? mammals
3. Wanted children are less likely to suffer abuse ü Therefore, on the basis of functionally-defined
personhood, newborns fail the test could be killed on
WOMEN HAVE A “RIGHT” TO CONTROL THEIR the basis of “non-personhood”
OWN BODY
1. Is the fetus part their body? WHEN DOES A HUMAN BECOME A PERSON?
- Separate circulatory system
- At conception
- Unique DNA
- After 20 weeks’ gestation
2. Do we have rights to do anything with our bodies?
- After 24 weeks (fetal viability outside the womb)
- Assault. Illegal drugs and Use of drugs/alcohol during - At birth
pregnancy
- At the point that the individual expresses self-
consciousness and an interest in their continued
POPULATION CONTROL – REBUTTAL existence
Ø Those countries that outlaw abortion have an AT CONCEPTION, IT IS ONLY A SINGLE CELL
overcrowding problem Claim: Fertilized eggs are single cells, like blood cells or other
Ø This does not indicated cause and effect – these countries parts of the body
also have little or no access to birth- control, poor Rebuttal:
education, etc. Ø The single cell is unique from both the father’s and
Ø War, disease and famine also curb population growth. mother’s cells and is the beginning of every new human
Should we condone them? being
Claim: PRIOR TO 20 WEEKS, A FETUS IS NOT A PERSON
FETUS IS NOT A PERSON Ø A person possess an individual human personality
Ø “Persons . . . are members of a social community that Ø Prior to 20 weeks’ gestation, the cerebral cortex has not
shapes and values them, and personhood must be defined yet developed to the point that the fetus can possess an
in terms of interactions and relationships with others.” individual human personality Therefore...
Ø Personality definition problems Ø The fetus prior to 20 weeks’ gestation is not a person.
1. Does a human non-person exist?
Rebuttal:
2. What traits define personhood?
Person = Personality Problem
BIOTHETICS PRELIMINARY TOPICS (Compiled: dpgomez, RN) 12
Ø All persons were once fetuses. When did we go from non-
person status to person status?
ABORTION NOT EVEN WHEN THE CHILD HAVE A
Ø To say that personality defines personhood is to deny the DISABILITY?
role of the body
Ø Preborn children diagnosed with disabilities deserve to be
Ø Mind/Body dualism?
treated with te same respect as born people with or
Ø Brain Development Problem without disability.
Ø The development of the brain is programmed by the DNA ABORTION WHAT IF THE BABY WILL DIE ANYWAY?
– it is an inherent function of the fertilized ovum and Ø Parents who know that they allowed God to have control
continues even after birth over the life of their little baby hae a much easier time
Rebuttal: grieving the loss of their baby than those parents who
PRIOR TO 24 WEEKS, A FETUS IS NOT VIABLE caused the death of their child abortion.
- Depends upon current technology Age of viability ABORTION NOT EVEN WHEN THE PREGNANCY IS THE
used to be 28 weeks Changed to 24 weeks in 1990 RESULT OF RAPE?
Ø Rape is an act of iolence inflicted upon a woman. She is
- Artificial womb (Nature, 2002)
Developed for
an innocent victim, and this knowledge may someday
premature infants
Uses oxygenated perfluorinated help her come to terms with the rape and rebuild her life.
hydrocarbons Could cut the point of fetal viability in ABORTION NOT EVEN WHEN THE PREGNANCY IS THE
half? RESULT OF RAPE?
Ø Her baby is not a monster, and telling a woman that her
WHAT THE CATECHISM OF THE CATHOLIC best option is to get rid her baby as soon as possible may
CHURCH only reinforce in her mind the idea that she is dirty, or a
HAS TO SAY ABOUT ABORTION: monster, herself.
ABORTION NOT EVEN WHENT THE PREGNANCY
HUMAN LIFE IS SACRED THREATENS THE LIFE OF THE MOTHER?
Ø Because from its beginning it involves the creative action Ø Abortion will not cure any life-threatening condition a
of God and it remains for ever in a special relationship mother might have.
with the Creator, who is its sole end. Ø In certain circumstances, pregnancy may, in fact, relieve
Ø God alone is the Lord of life from its beginning until its a medical condition.
end: no one can under any circumstance claim for himself
the right directly to destroy an innocent human being. THE EMBRYO MUST BE DEFENDED AS A PERSON
Ø Since it must be treated from conception as a person, the
HUMAN LIFE MUST BE PROTECTED FROM embryo must be defended in its integrity, cared for, and
CONCEPTION healed, as far as possible, like any other human being.
Ø Human life must be respected and protected absolutely Ø Prenatal diagnosis is morally licit, "if it respects the life
from the moment of conception. and integrity of the embryo and the human fetus and is
Ø From the first moment of his existence, a human being directed toward its safe guarding or healing as an
must be recognized as having the rights of a person - individual. . . .
among which is the inviolable right of every innocent Ø It is gravely opposed to the moral law when this is done
being to life. with the thought of possibly inducing an abortion,
Ø Before I formed you in the womb I knew you, and before depending upon the results: a diagnosis must not be the
you were born I consecrated you. (Jer 1:5)
equivalent of a death sentence.
Ø My frame was not hidden from you, when I was being "IT IS IMMORAL TO PRODUCE HUMAN EMBRYOS
made in secret, intricately wrought in the depths of the INTENDED FOR EXPLOITATION AS DISPOSABLE
earth. (Ps 139:15)
BIOLOGICAL MATERIAL."
Ø "One must hold as licit procedures carried out on the
DIRECT ABORTION IS GRAVELY CONTRARY TO human embryo which respect the life and integrity of
THE MORAL LAW the embryo and do not involve disproportionate risks for
Ø Since the first century the Church has affirmed the moral it, but are directed toward its healing the improvement
evil of every procured abortion. This teaching has not of its condition of health, or its individual survival."
changed and remains unchangeable. Ø "Certain attempts to influence chromosomic or genetic
Ø Direct abortion, that is to say, abortion willed either as an inheritance are not therapeutic but are aimed at
end or a means, is gravely contrary to the moral law: producing human beings selected according to sex or
Ø You shall not kill the embryo by abortion and shall not other predetermined qualities. Such manipulations are
cause the newborn to perish. (Didache 2,2:ÆCh 248,148) contrary to the personal dignity of the human being and
his integrity and identity" which are unique and
Ø God, the Lord of life, has entrusted to men the noble unrepeatable.
mission of safeguarding life, and men must carry it out in
a manner worthy of themselves. Life must be protected
with the utmost care from the moment of conception:
abortion and infanticide are abominable crimes.
(Gaudium et spes
S 51 § 3)
BIOTHETICS PRELIMINARY TOPICS (Compiled: dpgomez, RN) 13
BODILY INTEGRITY
Arlette Sanchez Samaniego, MD, FPAFP Sources:
- PPT
PRINCIPLE of TOTALITY - PAT G and VISION Transes
× The parts of the physical whole , inasmuch as they are
parts, are ordained to the good of the whole because
this good is what gives fundamental meaning, or the
raison d’etre, to the whole.
CLASSIFICATION of
ORGAN TRANSPLANTS
1. Autotransplants: autografts, auto plastic grafts
2. Heterologous transplants
a. Homologous transplant
> homotransplants, homografts, homoplastic grafts
or homologous transplants
Criteria for Donors
1. A least 12 months old and no more than 60 years old
2. No existing morbidities
3. Organ donated must not be strictly essential to life
4. Donation must be voluntary with an upright intention
5. Donor must understand all the risks involved
PRINCIPLE of FINALITY
Ø A healthy person may voluntarily donate any part of his
body that is not essential to his life, without contradicting
nature, for the benefit of a sick neighbor.
Ø Done out of generosity, which is frequently the case, this
gesture is not only justified; it is meritorious.
Ø Organ donation is fostered among Christians today as a
way of imitating Christ ‘who gave his life for the
salvation of others’ (Jn 3:14)
Having spent all the money, they tried to get stable jobs but
could not get accepted into various companies. With only one
kidney, they were not cleared during medical examinations.
They could also not handle the same physically-taxing jobs they
used to be able to take.