Syllabus For Master of Science in Chemistry: The Assam Kaziranga University, Jorhat

THE ASSAM KAZIRANGA UNIVERSITY, JORHAT
SYLLABUS
For
MASTER OF SCIENCE
In
CHEMISTRY
(Batch 2018-20)
SCHOOL OF BASIC SCIENCES
Course Structure:
Master of Science in Chemistry
Total Credit 89
Code Course L T P C Marks
Semester –I
BS2201 Conceptual Inorganic Chemistry 3 1 0 4 100
BS2202 Stereochemistry and Principles of 3 1 0 4 100
Organic Synthesis
BS2222 Principles of Physical Chemistry 3 1 0 4 100
BS2211 Quantum and Computational Chemistry 3 1 0 4 100
BS2239 Inorganic Chemistry Laboratory 0 0 12 6 100
Total 12 4 12 22 500
Semester-II
BS2228 Transition Metal Chemistry 3 1 0 4 100
BS2206 Organic Reactions and Mechanism 3 1 0 4 100
BS2207 Chemical Dynamics and 3 1 0 4 100
Electrochemistry
BS2208 Group Theory and Spectroscopy 3 1 0 4 100
BS2229 Organometallic and Bioinorganic 3 0 0 3 100
Chemistry
BS2240 Organic Chemistry Laboratory 0 0 12 6 100
Total 15 4 12 25 600
Semester-III
BS2209 Advanced Topics in Inorganic 3 1 0 4 100
Chemistry
BS2210 Heterocyclic Chemistry 3 1 0 4 100
BS2226 Environmental and Green Chemistry 3 0 0 3 100
BS22* Elective I 3 1 0 4 100
BS22** Elective II 3 1 0 4 100
BS2241 Physical Chemistry Laboratory 0 0 12 6 100
Total 15 4 12 25 600
Semester-IV
BS22*** Elective III 3 1 0 4 100
BS2227 Research Methodology and Analytical 3 0 0 3 100
Techniques
BS2238 Dissertation 0 0 20 10 200
Total 6 1 20 17 400
Total (Overall) 48 13 56 89 2100
Specializations:
a. Organic Chemistry
b. Inorganic Chemistry
c. Physical Chemistry
Students have to choose any one for the Elective I, Elective II and Elective III according to their
choice of specialization.
*Elective I:
a. Natural Product Chemistry (BS2212)
b. Advanced Organometallic Chemistry (BS2213)
c. Polymer Chemistry (BS2230)
**Elective II:
a. Advanced Topics in Organic Chemistry (BS2216)
b. Bioinorganic Chemistry (BS2225)
c. Catalysis and Surface Chemistry(BS2242)
***Elective III:
a. Medicinal Chemistry (BS2219)
b. Industrial Chemistry (BS2224)
c. Chemistry of Materials (BS2221)
SEMESTER I
The Assam Kaziranga University
School of Basic Sciences
M. Sc. (Chemistry)
BS2201: Conceptual Inorganic Chemistry 4 (3-1-0) Semester I
Rationale:
To provide a strong base to students that necessary to study the advanced inorganic chemistry.
Catalog Description:
It covers fundamental topics of inorganic chemistry from atomic structure and bonding to solution chemistry.
Pre-requisite:
Basicconceptions of atomic structure as well as bonding, and reactivity of inorganic compounds are essential.
Basic conceptions of mathematics and physics will also be needed.
Course Outline:
1. Periodic properties and bonding (24 Lectures)

Periodic properties, Ionic bonding, Valence bond theory, LCAO-MO theory, Orbital symmetry and
overlap, Walsh diagram, Bond energy and covalent radii, Metallic bonding, Band theory, Hydrogen
bonding, Clathrates, VSEPR model and the use of outer d-orbitals, Electronegativity (Pauling,Mulliken and
Allred-Rochow methods); Group electronegativity and polarity of bonds; Bonding in alloys, Intermetallic
compounds.
Stereochemistry and bonding in non-transition element compounds, Phosphonitrilic compounds.
2. Oxidation and reduction reactions (5 Lectures)

Use of redox potential data, Analysis of redox cycles, Redox stability in water, Disproportionation, Frost,
Latimer and Pourbaix diagrams; Applications in metal extractions.
3. Acids and bases: (5 Lectures)

Generalized acid base concept including HSAB concept.
4. Aspects of d- and f-block elements (14 Lectures)

Elements of first transition series and their comparison with the second and third series, General periodic
trends, Chemistry of various oxidation states of first row transition metals and their comparison with the
second and third row transition metals based on electronic configuration.Lanthanide contraction, Oxidation
states of f-block elements, Complexes of lanthanides and actinides,
Radioactivity: Nuclear structure and stability, Radioactivity, Principles of fission and fusion, Natural and
artificial radioactivity, Nuclear reactor, Application of radioisotopes.
Text Book(s):
1. Housecroft C.E., Sharpe A.G., Inorganic Chemistry, 4thedn., (Pearson 2012).
2. Huheey J.E., Keiter E. A., Keiter R.L., Medhi O.K., Inorganic Chemistry: Principles of Structure and
Reactivity, 4th edn., (Pearson, 2006).
3. Miessler G., Tarr D.A., Inorganic Chemistry, 3rdedn.,(Pearson, 2008).
Reference Book(s):
1. Atkins P., Overton T., Rourke J., Weller M., Armstrong F., Inorganic Chemistry, 5thedn.,(Oxford University
Press, 2006).
2. Cotton F.A., Wilkinson G.,Murillo C.A., Bochmann M., Advanced Inorganic Chemistry, 6thedn., (John
Wiley, 1999).
3. Douglas B., McDaniel D., Alexander J., Concepts and Models in Inorganic Chemistry, 3rdedn., (John Wiley
& Sons, 1994).
4.Porterfield W.W., Inorganic Chemistry A Unified Approach, 2ndedn., (Academic Press, 2009).
5. Arnikar H.J., Essential of Nuclear Chemistry, 4thedn., (New Age International Publishers Ltd., 2013).
E-Resources:
Journals and Magazines:
Grading System:
The final grade will be based on the following weight distribution:
- Internal Evaluation (30%)
- End Semester Examination (70%)

M. Sc. (Chemistry)
BS2202: Stereochemistry and Principles of Organic Synthesis4 (3-1- 0) Semester I

Rationale:
It is important to learn how to draw reasonable mechanism for organic reactions because mechanisms are the
framework that gives sense to organic chemistry. Understanding and remembering the bewildering array of
reactions known to organic chemists would be completely impossible if it was not possible to organize them
into just a few mechanistic types. The ability to formulate mechanistic hypothesis about how organic reactions
proceed is also required for discovery and optimization of new reaction.
This is a course in organic chemistry which will cover few basic mechanistic type like substitution by SN1
and SN2, elimination reaction, addition of nucleophiles to carbon- carbon multiple bond, addition to carbonyl
group, pericyclic reaction and free radical reactions. Principles of Stereo chemistry which is very essential to
understand organic reaction mechanisms are also covered.
Pre-requisite:
Basic idea of structure and bonding,stereochemistry and ways of representing organic structures.
Course Outline:
1. Stereochemistry: (12 Lectures)

Principles of Stereochemistry: Stereoisomerism in organic compounds,Concept of conformational and
configurartional isomerism; Fischer, Newman and Sawhorse formula; effect of conformation on
reactivity. Neighbouring group participation; Chirality,E-Z isomerism, R-S nomenclature;configurational
and conformational isomerism of simple cyclic and acyclic systems, stereogenicity, stereoselectivity,
enantioselectivity, diastereoselectivity.Racemic modification and optical purity; resolution of
isomers,determination of enantiomeric and diastereomeric excess; enantiodiscrimination.Newer methods
of asymmetric synthesis (including enzymatic and catalytic nexus),asymmetric induction, methods of
asymmetric induction – substrate, reagent and catalytically controlled reaction.Enantio- and Diastereo
selective synthesis, Topicity and prostereoisomerism;
2. Structure and reactivity: (3 Lectures)
Linear free energy relationships, Hammett and Taft equations, σ and ρ parameters; Applications of acid-
base concept, HSAB theory; Huckel rule, Aromaticity in benzenoid and non-benzenoid compounds,
antiaromaticity and homoaromaticity; n-annulenes, heteroannulenes, fullerenes, cryptates.
3. Substitutionreactions: (7 Lectures)
Substitution at saturated carbon by SN1 and SN2 elimination addition and SET, substitution at carbonyl,
alkenyl and aryl Carbon, Parameters influencing reaction rates; Neighboring group participation by π and
σ bonds, Anchimeric assistance; Synthetic applications of nucleophilic substitution involving alcohols,
thiols, amines and hydrides; 1,3-dithiane reactivity, Umpolung effect; Aromatic nucleophilic and
electrophilic substitution, aromatic substitution of aniline.
4. Elimination reactions: (5 Lectures)

Mechanism and stereochemistry of different types of elimination reactions; Effects of substrate structure,
attacking base, leaving group and medium; Competition betweensubstitution and elimination; Formation
of other double bonds (C=N, C=O) and triple bonds by elimination reactions; Mechanism and orientation
in pyrolytic elimination.
5. Addition to carbon-carbon multiple bonds: (5 Lectures)

Mechanistic and stereochemical aspects of addition reactions involving electrophiles, nucleophiles and free
radicals; Regio- and chemo-selectivity; Orientation and reactivity; Addition to cyclopropane and carbon-
heteroatom multiple bonds; 1,2 and 1,4- addition reaction, Hydroboration, alkylation, epoxidation and
hydroxylation; Addition of halogen polar reagents to alkenes.
6. Carbonyl and related groups: (6 Lectures)

Homologation and de-homologation of carbonyl compounds; Nucleophilic addition of hetero-atoms
(N,O,S);Acylation of carbonyl carbon; Carbonyl cyclizations and cleavages; Carboxylic acids and
derivatives, decarboxylation reactions.
7. Photochemical reaction: (4 Lectures)

Photochemical reaction of alkenes and carbonyl compounds; Photooxygenation; Photochemistry of
aromatic compounds; Photochemical isomerisation, addition and substitution;Photo-Fries rearrangement
of ethers and anilides; Barton reaction, Hoffmann-Loefller-Freytag reaction, di-π-methane rearrangement;
Singlet molecular oxygen reactions; Photo-cleavages.
8. Pericyclicreactions: (6 Lectures)
Main features of pericyclic reactions; Woodward-Hoffman rules, correlation diagram and FMO
approaches; Electrocyclic reactions: conrotatory and disrotatory motions for 4n and 4n+2
systems;Cycloadditions–antarafacial and suprafacial additions, [2+2] and [4+2] reactions (hνandΔ), 1,3-
dipolar cycloadditions and chelotropic reactions; Sigmatropic[i,j] shifts of C-H and C-C bonds; Sommelet-
Hauser, Claisen, thio-Claisen, Cope and aza-Cope rearrangements.
Text Book(s):
1. DepuyC., Chapman O.L.,Molecular Reactions and Photochemistry, (Prentice-Hall of India, 1975).
2. March J.,Advanced Organic Chemistry: Reactions, Mechanisms and Structure,4thedn.,(John Wiley & Sons
Asia Pvt. Ltd., 2005).
3. NasipuriD.,Stereochemistry of organic compounds: Principles and Application, 4thedn., (New Academic
Science, 2012).
4. Pine S.H.,Organic Chemistry,5thedn.,(McGraw-Hill, 1987).
Reference Book(s):
1. Carey F.A., Sandburg R.J.,Advanced Organic Chemistry: Part A and B, 5thedn., (Springer, 2008 and 2010).
2. FlemingI.,Frontier Orbital Theory and Organic Reactions, (John Wiley & Sons, 1976).
3. Grossman R.B., The Art of Writing Reasonable Organic Reaction Mechanisms, 2ndedn., (Springer,
2010).
4. Harris J.M., Wamser C.C., Fundamentals of Organic Reaction Mechanisms, (Wiley, 1976).
5. MarchandA.P., Lehr R.E., Pericyclic Reactions, (Academic Press, 1977).
6. Woodward R.B., HoffmanR., Conservation of Orbital Symmetry, (Verlag-Chemie/Academic Press, 1970).
E-Resources:
Grading System:
Academic Council Approval:

M. Sc. (Chemistry)
BS2222: Principles of Physical Chemistry 4 (3-1-0) Semester I
Rationale:The objective is to make the concepts of thermodynamics, quantum chemistry and

macromolecules clear and interesting to students.
Catalog Description:Integrating coverage of thermodynamics, macromolecules and basic quantum
chemistry into a single course and carefully structured to provide a clear and consistent resource for
beginners. Explores fully the principles of equilibrium, non-equilibrium and statistical thermodynamics,
macromolecules and quantum chemistry.
Pre-requisite: Knowledge of physical principles and mathematics.
Course Outline:
1. Equilibrium thermodynamics (12Lectures)

Review of the laws of thermodynamics, free energy, chemical potential Concept and determination of
fugacity,and activityt, Debye-Hückel theory for activity coefficient of electrolytic solutions; ionic
strength.
Partial molar quantities, Gibb’s Duhem equation, thermodynamics of mixing.
Application of phase rule to three component systems: triangular plots, water-acetic acid-chloroform
system.
2. Non-Equilibrium thermodynamics (5 9Lectures)

Entropy production and entropy flow, relation between forces and fluxes, microscopic reversibility and
Onsager’s reciprocity relations
3. Statistical thermodynamics (5 9Lectures)

Ensembles, Maxwell Boltzmann distribution, partition functions
4. Macromolecules (7 9Lectures)
Polymer and polymerization, chain (free radical) and step polymerization, Kinetics of chain
polymerization, Molecular weights and their masses, determination of molecular masses, osmometry
and viscometry, light scattering, .
5. Solids (6 Lectures)
Space lattice, unit cell, symmetry in crystal systems, Bravais lattices, Weiss and Miller indices,Bragg’s
equation, simple, bcc, fcc, relation between r and a, radius ratio, packing fraction, close packing in 3D,
density, defects in crystrals, ionic crystals.
6. Colloids (6 Lectures)
Definition of colloids and crystalloids, classification of colloids, preparation and purification techniques of
colloidal dispersion, Tyndal effect, Brownian movement, electrophoresis, electro-osmosis, protective
colloids, gold number, zeta potential, lyophilic, lyophobic, ampiphilic colloids, gels, emulsifiers,
stabilization by emulsification, micelles, critical micelles concentration(CMC).
5. Bio-physical chemistry (5 11 Lectures)

Bioenergetics-standard free energy change in biochemical reactions, chemistry involved in oxidative
phosphorylation. Configuration of biological macromolecules; polypeptide and protein structure, protein
folding. Enzymes-classification and catalysis; Enzyme regulators and inhibitors
Text Book(s)
1. Atkins P.W., de PaulaJ.,Physical Chemistry,9thedn.,(W.H. Freeman, 2009).
2. Billemeyer F.,Textbook of Polymer Science 3rdedn.,(John Wiley& Sons, 1984).
3. Castellan G.W.,Physical Chemistry, 3rdedn., (Narosa Publishing House, 2003).
4. Lehninger A.L., Nelson D.L., Cox M.M., Lehninger Principles of Biochemistry, 4thedn., (Palgrave
Mcmillan, 2004).
Reference Book(s)
1. Engel T., Reid P., Physical Chemistry, 3rdedn., (Prantice Hall, 2012).
2. Kalidas C., Sanganarayana M. V., Non-Equilibrium Thermodynamics: Principles and
Applications(Macmillan India, 2002).
3. Stumpf P.K., Conn E.E., Bruening G., Roy H.D., Outline of Biochemistry, 5thedn., (Wiley India Pvt.
Ltd., 2006).
E-Resources:
Grading System:

M. Sc. (Chemistry)
BS2211: Quantum and Computational Chemistry 4 (3-1-0)Semester-I
Rationale:
Understanding of the elementary principles of quantum mechanics, electronic structure of atoms and their
periodicity, electronic structure of molecules and chemical bonding will help to perform quantum-chemical
calculations.
Details of quantum mechanics for study of chemical systems.
Pre-requisite:
Knowledge of mathematics and physical principles.
Course Outline:
1. Fundamental principles and applications to simple systems (16Lectures)

Origin of the quantum theory,postulates of quantum mechanics, linear and
Hermitianoperators,commutation of operators and uncertainty principle, postulates, properties of wave
functions, Schrodinger equation, energy eigenvalue equation, equation of motion and constant of
motion,exactly solvable problems,particle in a box, harmonic oscillator, rigid rotator, step potential and
tunneling, hydrogen atom.
2. Atomic structure (28Lectures)

The variation theorem; linear variation principle, perturbation theory, applications of variational methods
and perturbation theory to the helium atom,ordinary angular momentum, generalized angular momentum,
eigenfunctions, and eigenvalues of angular momentum operator, Ladder operator, addition of angular
momenta,spin, antisymmetry, Pauli exclusion principle, Slatter-determinantal wave functions,term symbol
(RS and jj coupling) and spectroscopic states, term separation energies of pn and dn configurations,
magnetic effects: spin-orbit coupling and Zeeman splitting, Hellmann-Feynmann theorem,antisymmetry
principle and many-electron wave functions,virial theorem, Born-Oppenheimer approximation, valence
bond (VB) and molecular orbital (MO) theory for diatomic molecules – hydrogen molecule ion, hydrogen
molecule; excited states of H2: singlet and triplet, non-crossing rule and correlation diagram,
hybridization,Huckel MO treatment for simple and conjugated polyenes, Hybridisation and valence MOs
of H2O, NH3 and CH4, Introduction to the SCF.
3. Computational chemistry (6Lectures)

Introduction to internet and computer, historical perspectives of computational chemistry, computable
quantities: structure, potential energy surface, chemical properties.
Text Book(s):
1. Atkins P.W. Friedman R.S., Molecular Quantum Mechanics 3rd Ed., (Oxford Univ. Press, 1997).
2. McQuarrie D.A., Quantum Chemistry, (Viva Books Pvt. Ltd., 2011).
3. PilarF.L., Elementary Quantum Chemistry, 2ndedn., (Dover Publications Inc., NY, 1990).
Reference Book(s):
1. Atkins P.W.,De PaulaJ.,Physical Chemistry,9thedn.,(W.H. Freeman, 2009).
2. Chandra A.K., Introduction to Quantum Chemistry,(Tata McGraw Hill).
3. LevineI.N., Quantum Chemistry, 7thedn., (Prentice Hall India, 2013).
Journals:
E-Resources:
Grading System:

M. Sc. (Chemistry)
BS2239: Inorganic Chemistry Laboratory 6 (0-0-12) Semester I
Rationale:
Laboratory work at postgraduate master’s level course is essential to produce skilled technicians for industry
and highly competent workers for research laboratories.
This course has included different analytical and synthetic methodologies, which will help students’ analytical
skill to undertake academic and industrial research work.
Pre-requisite:
Basic experimental skills, conceptions of acids and bases, safety rules in chemical laboratory.
Course Outline:
A. Quantitative analysis
Quantitative estimation involving volumetric, gravimetric and spectrophotometric methods of constituents
in three component mixtures, alloys, ores, minerals etc.
B. Synthesis and characterization of inorganic compounds

Synthesis of inorganic compounds, including those involving new synthetic methodology.
Characterization by using any of the following techniques: elemental analysis, conductance
measurements,and infrared (IR/FTIR), UV-Visible, Thermal Analysis, Cyclic Voltammetry;
Text Book(s):
1. Marr G., RockettB.W., Practical Inorganic Chemistry, (Van Nostrand, 1972).
2. Mendham J.,Danney R.C., BarnesJ.D., ThomasM., Vogel’s Textbook of Quantitative Chemical Analysis,
(Pearson Education, 2000).
3. PassG., SutcliffeH.,Practical Inorganic Chemistry, 2ndedn.,(Chapman & Hill, 1974).
Reference Book(s):
1. BassetJ., Denney R.C., Jeffery G.H., MendhamJ., Vogel’s Text Book of Quantitative Analysis, 4thedn.,
(English Language Book Society, 1978).
2. Day R.A. Underwood A.L., Quantitative Analysis, 6thedn., (PHI, Delhi, 2013).
E-Resources:
Grading System:

SEMESTER II
M. Sc. (Chemistry)
BS2228:Transition Metal Chemistry 4 (3-1-0)Semester II
Rationale:
To provide a sound knowledge of transition metal chemistry, which will help the students for further advanced
learning in inorganic chemistry.
Detail properties of transition metal chemistry and basics of organometallic chemistry.
Pre-requisite:
Knowledge of periodic table, basic transition metal chemistry and co-ordination chemistry.
Course Outline:
1. Bonding in transition metal complexes (11 Lectures)

Crystal Field Theory, The splitting of d-orbitals in various fields,Adjusted crystal field theory,Molecular
orbital theory of complexes (including complexes with and without π bonding), MO diagrams of
octahedral, tetrahedral and square planar complexes, Jahn-Teller effect, Splitting of f-orbitals in octahedral
field, thermodynamic effects: hydration, ligation and lattice energy..
2. Electronic structure and spectra of transition metal complexes (10Lectures)
Interpretation of electronic spectra, Selection rules, Spectroscopic states, Orgel and Tanabe-Sugano
diagrams, band intensities and band width, Spectrochemical and Nephelauxetic series, Charge-transfer
spectra, Optical properties of lanthanides and actinides.
3. Magnetic properties of transition metal complexes (4 Lectures)
Types of magnetic behaviour: dia-, para-, ferro- and anti-ferromagnetic compounds, Spin-orbit coupling,
Temperature independent paramagnetism, Application of crystal field theory to explain magnetic
properties, Spin- crossover.
Magnetic properties of lanthanides and actinides.
4. ESR and Mossbauer spectra of transition metals (7 Lectures)
ESR spectroscopy: Origin of g-shifts and hyperfine coupling, line shape; ESR of d1and d9transition metal
ions in cubic and tetragonal ligand fields; evaluation of g values and metal hyperfine coupling constants.
Mossbauer spectroscopy: Principles, isomer shift, quadruple effect of magnetic field, applications to iron
and tin compounds.
5. Metal-ligand equilibria in solution (5 Lectures)
Stepwise and overall formation constants,Trends in stepwise formation constants,Determination of binary
formation constant by spectrophotometry,Factors affecting stability of metal complexes and chelate effect.
6. Kinetics and mechanism of inorganic reactions (11 Lectures)

Labile and inert complexes,Mechanisms of ligand-replacement reactions,Ligand displacement reactions in
square planar and octahedral complexes,The transeffect,Isomerization and racemization of tris-chelate
complexes,Electron transfer reactions,Stereo-chemicalnonrigidity and fluxional molecules.
Text Book(s):
1. Housecroft C.E., Sharpe A.G., Inorganic Chemsitry, 4thedn., (Pearson, 2012).
2. Huheey J.E., Keiter E.A., Keiter R.L, Medhi O.K., Principles of Structure and Reactivity, 1stedn., (Pearson
Education, 2006).
3. Miessler G., Tarr D.A., Inorganic Chemistry, 3rdedn., (Pearson, 2008).
4. Janes R., Moore E., Metal-Ligand Bonding, The Open University, Royal Society of Chemistry, 2004.
5. Parish R.V., NMR, NQR, EPR and Mossbauer Spectroscopy in Inorganic Chemistry, (Ellis Horwood,
New York, 1990).
Reference Book(s):
1. Atkins P., Overton T., Rourke J., Weller M., Armstrong F., Inorganic Chemistry, 5thedn., (Oxford
University Press, 2006).
2. Carlin, R.L. Magnetochemistry, (Springer Verlag, 1986).
3. Cotton F.A., Wilkinson G., Murillo C.A., Bochmann M., Advanced Inorganic Chemistry, 6thedn., (John
Wiley, 1999).
4. Dutta, R.L., Syamal, A. Elements of Magnetochemistry, 2ndedn., (East-West Press, 1993).
5. Hay R.W. Reaction Mechanisms of Metal Complexes, (Woodhead Publishing, 2013).
6. Figgis B.N., Hitchman M.A., Ligand Field Theory and Its Applications, (Wiley India, 2000).
7. Drago R.S., Physical Methods in Inorganic Chemistry, Reinhold Publishing Corporation, New York, 1965.
8. Banwell C.N., McCash E.M., Fundamentals of Molecular Spectroscopy, 4thedn., (Tata McGraw-Hill, New
Delhi, 2006).
E-Resources:
Grading System:

M. Sc. (Chemistry)
BS2206: Organic Reactions and Mechanism4(3-1-0) Semester II
Rationale:
Organic functional group interconversion is one of the important areas in synthetic organic chemistry.
Knowledge of reduction, oxidation reaction, and reactive intermediates will give an insight to plane for
different conversions. To design new synthetic routes knowledge of disconnection approach is necessary.
This is a course in Organic Chemistry is covering the study of oxidation and reduction reactions, reactive
intermediates, and disconnection approach.
Pre-requisite:
Knowledge about oxidation and reduction, free radical, reactive intermediate.
Course Outline:
1. Reduction reactions: (14 Lectures)

(a) Catalytic hydrogenation: Scope and mechanisms for heterogeneous catalytic hydrogenation of alkenes
and other functional groups; Reduction selectivity; Catalyst poisoning and desulphurization; Homogeneous
catalytic hydrogenation with Wilkinson catalyst; Alkene double bond isomerisation, stereoselectivity,
concept and application of hydrogenoysis.
(b) Dissolving metal reductions: Scope and basic mechanisms; Liquid ammonia reduction withAlkali
metals, Birch reduction of arenes; Acyloin condensation and related reactions.
(c) Metal hydride reductions: Scope, stereochemistry and mechanism of metal Hydride reductions of
carbonyl compounds; Reduction of other functional groups like nitro, nitroso, azoandoxime groups; MPV
reduction; Use of hydroboration in reduction, oxidation and carbonylation, regioselectivity, stereo-
selectivity and synthetic utility of alkyl boranes.
(d) Reduction with hydrazine & derivatives: Reduction of carbonyl group with hydrazine;
tosylhydrazine, diimide and semicarbazide; Use of hydrazine with other reducing agents on conjugated
systems.
2. Oxidation reactions: (14 Lectures)

(a) Cr- and Mn-oxidations: Oxidation of alcohols & aldehydes with Cr (VI) &Mn(VII) oxidants;
Oxidation of C=C and C-H bonds; Uses of Sarrett reagent, PCC, PDC and Collin’s reagent.
(b) Peroxyoxidations: Alkene epoxidation by peracids and metal/alkyl hydroperoxides,
Sharpless asymmetric epoxidation.
(c) Other methods of oxidation: DMSO and Swern oxidations; Oppenauer oxidation; Prevost and
Woodward hydroxylation of alkenes; Oxidative cleavage of C-C single and double bonds; periodates, LTA,
oxidation of organic substrates with mercuric acetate and SeO2, Oxidative rearrangement and cyclization.
3. Reactive intermediates: (14 Lectures)

(a) Carbenes: Stability, structure and spin states of carbenes; Cyclopropanation-spin dependence and
stereochemistry; Carbene insertion to C-H bonds; Rearrangement to alkenes; Wolff rearrangement of
acylcarbenes and its synthetic applications; Carbenoids.
(b) Nitrenes: Stability, structure and spin states of nitrenes; C-H bond insertions and aziridine formation;
Rearrangement of acylnitrenes (Hoffmann, Curtius and Schmidt reactions with applications in organic
synthesis); Nitrenoids.
(c) Free radicals: Stability and fate of organic free radicals; Metal-induced radical reactions; Radical
cyclisation and coupling reactions; Addition to multiple bonds; Aromatic substitution by radicals;
Allylicbromination by NBS and decarboxylativebromination;
4. Disconnection approach: (8 Lectures)

Disconnection approach, Synthonand type of synthons, one group and two group disconnections, reversal
of polarity, chemo selectivity, one group C-C, C-X disconnections, Domino reactions and multicomponent
reaction
Text Book(s):
1. Gilchrist T.L., Rees C.W., Carbenes, Nitrenes and Arynes, (Nelson, London, 1969).
2. KalsiP.S., Organic Synthesis Through Disconnection Approach, 1stedn.,(Medteck, 2014).
3. March J., Advanced Organic Chemistry: Reactions, Mechanisms and Structure, 4thedn.,(Wiley Student
Edition, John Wiley & Sons Asia Pvt. Ltd., 2005).
Reference Book(s):
1. HouseH.O., Modern Synthetic Reactions, (W. A. Benjamin, 1972).
2. WarrenS., WyattP., Organic Synthesis: The Disconnection Approach, 2ndedn.,(Wiley, 2008).
E-Resources:
Grading System:

M. Sc. (Chemistry)
BS2207: Chemical Dynamics and Electrochemistry 4 (3-1-0) Semester II
Rationale:If gases do exist as particles then they must be explainable on this basis – kinetic molecular model.
This reading is essential for the understanding of advanced learning in chemical kinetics and advanced
electrochemistry.
Catalog Description:This course deals with the experimental and theoretical aspects of chemical reaction
kinetics and electrochemistry.
Pre-requisite:Strong background in chemistry at the degree level. Knowledge of mathematics is required.
Course Outline:
1. Chemical dynamics (25 30Lectures)

Empirical rate laws, Methods of determinations of reaction rates, theories of reaction rates – Arrhenius
theory, collision theory, steric factor, activated complex theory, reactions in solutions, ionic reactions,
kinetic salt effect, reactions on solid surfaces and solid state reactions. Treatment of unimolecular reactions,
steady state kinetics. Composite reactions parallel, consecutive, photochemical, chain reactions and
oscillatory reactions.
Fast reactions, luminescence and energy transfer, study of fast reactions by flow method, relaxation method,
flash photolysis, Temperature and Pressure jump and nuclear magnetic resonance method. Reaction
dynamics, dynamics of molecular motions, probing the transition state, potential energy surface, Electron
transfer and proton transfer reactions, dynamics of unimolecular reactions Lindemann-Hinshelwood and
RRKM theory.
Homogeneous and heterogeneous catalysis, enzyme catalysis, phase transfer catalysis.
2. Electrochemistry: (15 20Lectures)

Electrochemical cells, cell reactions, Nernst equation, Thermodynamics of electrochemistry, electrode
kinetics, electrical double layer, various models, electrode/electrolyte interface, ion transport, diffusion,
over potential, Butler-Volmer equation, Tafel plot, dynamic electrochemistry, corrosion and its prevention,
batteries, solid state battery, fuel cells, Polarography, half-wave potential.
Text Book(s):
1. Atkins P.W.,De PaulaJ.,Physical Chemistry, 9thedn.,(Oxford University Press, 2009).
2. Laidler K., Chemical Kinetics, (Harper and Row, 1995).
Reference Book(s):
1. BockrisJ.O.M., Reddy A.K.N., Modern Electrochemistry, Volume 1 and 2, (Kluwer Academic, 2000).
2. Pilling M.J.,SeakinsP.W., Reaction Kinetics, (Oxford Press, 1997).
E-Resources:
Grading System:

M. Sc. (Chemistry)
BS2208: Group Theory and Spectroscopy 4 (3-1-0) Semester II
Rationale:
The knowledge of group theory and spectroscopy is important to provide a framework to understand the
structure and bonding in molecules.
Catalogue Description:
General principles of group theory and all aspects of spectroscopy and its applications to simple chemical
systems.
Prerequisite:
Fundamentals of chemistry, theoretical knowledge of analytical principles as well as the basic conceptions of
mathematics and physics are essential to understand the topics.
Course Outline:
1. Chemical applications of group theory (16Lectures)

Symmetry elements and symmetry operations; symmetry groups; molecular dissymmetry and optical
activity; symmetry point groups for compounds having co-ordination number 2 to 9, matrix representation
of groups, reducible and irreducible representation, the great orthogonality theorem, applications of
symmetry concepts in vibrational spectroscopy and molecular orbital description of molecules.
2. Rotational and vibrational spectra (7 Lectures)

Pure rotational, vibrational and vibrational-rotational spectra of diatomic molecules, pure vibrational
spectra of polyatomic molecules: normal coordinate analysis, symmetry of normal coordinates; group
theoretical derivation of selection rules, Fermi resonance, theory of Raman scattering, rotational,
vibrational and vibrational-rotational Raman spectra of molecules;IR and Raman spectroscopy in structure
determination of organic and inorganic compounds.
3. Electronic spectra (5 Lectures)

Frank-Condon principle, electronic spectra of polyatomic molecules, electronic transitions, change of
molecular shape on electronic excitation, selection rule, intensity and oscillator strengths.
4. Mass spectrometry (6 Lectures)

Basic principles and instrumentation, mass spectral fragmentation of organic compounds, applications.
5. Nuclear magnetic resonance (NMR) spectroscopy(13 Lectures)

Basic principles, origin of chemical shifts, spin-spin coupling, relaxation processes, approximate chemical
shift values of various chemically non-equivalent protons and correlation to protons bonded to carbon
(aliphatic, olefinic, aldehydic and aromatic); protons bonded to other nuclei (alcohols, phenols, enols,
carboxylic acids, amines, amides, SH); chemical exchange, effect of deuteration; complex spin-spin
interaction between two, three, four and interacting nuclei (first order spectra); complex interaction, virtual
coupling, stereochemically hindered rotation, karplus curve, variation of coupling constant with dihedral
angle, nuclear magnetic double resonance, simplification of complex spectra using shift reagents, Fourier
transform technique and nuclear Overhauser effect (NOE).
6. 13C NMR spectroscopy (3 Lectures)

Chemical shift (aliphatic, olefinic, alkynes, aromatic, hetero-aromatic, carbonyl carbon); coupling
constants, two-dimensional NMR spectroscopy, NOESY, DEPT and INEPT terminologies.
Text Book(s):
1. Banwell C.N.,McCashE.M.,Fundamentals of Molecular Spectroscopy, 4thedn., (Tata McGraw-Hill, New
Delhi, 2006).
2. Cotton F.A., Chemical Application of Group Theory, 3rdedn. (John Wiley & Sons, 1999).
3. NakamotoK., Infrared and Raman Spectra of Inorganic and Coordination Compounds, 5thedn.,(John Wiley,
1997).
4. Silverstein R.M., BasselerG.C.,MorillT.C.,Spectroscopic Identification of Organic Compounds, (John
Wiley, 1981).
Reference Book(s):
1. DragoR.S.,Physical Methods in Chemistry, (Saunders College Publishers, 1977).
2. Harris D.C., Bertolucci M.D., Symmetry and Spectroscopy: An Introduction to Vibrational and Electronic
Spectroscopy, (Dover Publications Inc., New York, 1989).
3. Kemp W., Organic Spectroscopy, 3rdedn., (McMillan Press Ltd., 1991).
4. Parish R.V., NMR, NQR, EPR and Mossbauer Spectroscopy in Inorganic Chemistry, (Ellis Horwood,
New York, 1990).
5. RamanK.V., Group Theory andIts Applications to Chemistry, (Tata McGraw-Hill Publishing Company
Ltd., New Delhi).
6. Williams D., Fleming I., Spectroscopic Methods in Organic Chemistry, (McGraw Hill, 1989).
E-Resources:
Grading System:

M. Sc. (Chemistry)
BS2229: Organometallic and Bioinorganic Chemistry 3 (3-0-0) Semester-II
Rationale:
To provide a sound knowledge of organometallic and bioinorganic chemistry, this will help the students for
further advanced learning in these two important areas of chemistry.
The overall goal of this paper is to coversome basic and advanced level topics of related subjects, which are
essential for master level students.
Pre-requisite:
Knowledge of coordination-chemistry including bonding of polyatomic molecules and transition metal
complexes, basics of biological sciences.
Course Outline:
1. Organometallic chemistry(15 Lectures)

Common type of ligands: bonding and spectroscopy, Types of organometallic reactions, Metal carbonyls,
nitrosyls and dinitrogen complexes, Reactions involving co-ordinated ligands, Cyclometallation reactions,
Bonding, synthesis and reactivity of transition metal complexes with CO, NO, O2, N2 and tertiary phosphine
and arsine ligands.
Synthesis, structure, bonding and reactivity of transition metal complexes with olefins, cyclopentadienyl,
cyclopentadienide, benzenoid, π-allyl and enyl systems; Transition metal-carbon σ-bond: metal-alkyls,
metal-carbenes, metal-carbynes, double and multidecker sandwich complexes.
2. Homogeneous and heterogeneous catalysis (12 Lectures)

Hapticity of ligands, The 18-electron rule, Catalytic reactions of alkenes – isomerisation, hydrogenation,
carbonylation, hydroformylation and polymerization, Fischer-Tropsch process.
3. Bioinorganic chemistry (12 Lectures)

Scope, Inorganic elements in biological systems and their significance; Iron storage and transport-
siderophores, ferritin and transferring, Active transport of cations across membranes, Na+/K+ pump, Heme-
protiens – hemoglobin, and myoglobin; Electron transfer proteins-structure and functions of iron-sulphur
proteins, Cytochromes, Plastocyanine; Metal enzymes-nitrogenases and dioxygen fixation, Vitamin B12;
Toxicity of mercury, cadmium, lead, chromium, beryllium, selenium and arsenic with specific examples;
Inorganic drugs, Chelation therapy, Metals used for diagnosis and chemotherapy.
Text Book(s):
1. Gupta B.D., Elias A.J., Basic Organometallic Chemistry, 2ndedn., (Universities Press, 2013).
2. Housecroft C.E., Sharpe A.G., Inorganic Chemistry, 4thedn., (Pearson 2012).
3. Huheey J.E., Keiter E. A., Keiter R.L., Medhi O.K., Inorganic Chemistry: Principles of Structure and
Reactivity, 4th edn., (Pearson, 2006).
5. Rehder D., Bioinorganic Chemistry, 1stedn., (Oxford University Press, 2014).
Reference Book(s):
1. Atkins P., Overton T., Rourke J., Weller M., Armstrong F., Inorganic Chemistry, 5thedn.,(Oxford University
Press, 2006).
2. Cotton F.A., Wilkinson G.,Murillo C.A., Bochmann M., Advanced Inorganic Chemistry, 6thedn., (John
Wiley, 1999).
3. Mehrotra R.C., SinghA., Organometallic Chemistry: A Unified Approach, 2ndedn.,(New Age International,
2000).
M. Sc. (Chemistry)
BS2240:Organic Chemistry Laboratory 6 (0-0-12)Semester II
Rationale:
This course has included different analytical and synthetic methodologies, which will help students’ analytical
skill to undertake academic and industrial research work.
Pre-requisite:
Basic experimental skills, basic concept of organic chemistry, safety rules in chemical laboratory.
Course Outline:
A. Preparations of organic compounds using following reactions

1. Aldol condensation
2. Henry reaction
3. Esterification and organic acids and hydrolysis.
4. Reduction involving sodium borohydrate
5. PCC, PDC, Swern oxidation
6. Chan-lam coupling
7. Sujuki, Negishi, Heck and Stille coupling.
8. Buchwald coupling
9. Sandmayer reaction
10. Pegylation of phenolic OH
11. Protection of alcohol,amine and amino acid (Boc protection, tosylation, mesylation, benzylation)
12. Protection of carbonyl groups.
13. Synthesis of few heterocyclic compounds.
14. Reduction and hydrolysis of nitrile.
15. Nitration of aromatic compounds, Reduction of nitro group
B. Purification of organic compounds using
2. Column chromatography
2. Crystallization technique
3. Steam distillation
4. Sublimation
C. Analysis of organic products using 1H NMR, 13C NMR, LCMS, IR, determination of optical rotation.
Text Book(s)
1. Furniss B.S., Hannaford A.J., Rogers V., Smith P.W.G., Tatchell A.R., Vogel’s Textbook of Practical
Organic Chemistry, 4thedn., (ELBS, 1978).
2. Leonard J., Lygo B., Procter G., Advanced Practical Organic Chemistry, 3rdedn., (CRC Press, 2013).
3. Mann F.G., Saunders B.C., Practical Organic Chemistry, 4thedn., (Longman 1979).
Reference Book(s):
Grading System:

SEMESTER III

M. Sc. (Chemistry)
BS2209: Advanced Topics in Inorganic Chemistry 4 (3-1-0) Semester-III
Rationale:
Inorganic chemistry, a major branch of chemistry is a vast subject. Due to the continuous development of this
subject, it is necessary to include new topics in the curricula. The present paper is therefore developed to
include some topics, which are not possible to cover in the previous papers due to vast nature of inorganic
chemistry.
The overall goal of this paper is to cover some special topics in inorganic chemistry, whichare not possible to
cover in previous papers but the knowledge of these topics are essential for master level students.
Pre-requisite:
Knowledge of acid- base reactions, chemical kinetics, periodic properties, and basic conception of analytical
chemistry
Course Outline:
1. Cages, clusters, rings (12 Lectures)

Cages, clusters, rings – boranes, carboranes, metalloboranes and metallocarboranes, siloxanes, Hetero-
atomic rings,Metal carbonyl hydrides and metal carbonyl clusters: LNCC and HNCC, Wade’s rule and the
capping rule.
Metal-metal multiple bonds, Major structural types, Quadrupole bonds and One-dimensional solids.
3. Photochemistry of metal complexes and metal–metal multiple bonds (14 Lectures)

Excited states, Ligand field states, Charge-transfer states and Thexi states; Phosphoresence and
fluorescence; Photochemical reactions: substitution and redox reactions of Cr(III), Ru(II) and Ru(III)
complexes; Applications: synthesis and catalysis, Chemical actinometry and photochromism.
3. Supramolecular chemistry (6 Lectures)

Definition of supramolecular chemistry, Supramolecular host-guest compounds, Macrocyclic effect,
Nature of supramolecular interactions.
7. Basics of inorganic materials chemistry (12 Lectures)

Importance of inorganic materials chemistry, Synthesis of materials: solid state, solution based and
chemical deposition methods, Defects and ion transport: electrolytes, metal oxides and nitrides, High
temperature superconductor, Layered compounds and intercalation, Chelcogenidesthermoelectrics,
Framework structures, Hydrides, Inorganic pigments, Fullerides.
5. Nanomaterials (6 Lectures)
General introduction to nanomaterials and emergence of nanotechnology; Properties of nano-materials;
Characterization and fabrication; Thin films: chemical vapor deposition and Atomic layer deposition
techniques; Carbon based nanostructures: fullerenes, graphene and nanotubes, Bioinorganic nanoparticles,
Applications of nanoparticles and nano-materials.
Text Book(s):
1. Atkins P., Overton T., Rourke J., Weller M., Armstrong F., Shriver and Atkins Inorganic Chemistry,
5thedn., (Oxford University Press, 2010).
3. Huheey, J.E., Keiter, E.A., Keiter, R.L, Medhi, O.K., Principles of Structure and Reactivity, 1stedn.,
(Pearson Education, 2006).
5. Pradeep T., Nano: The Essentials, (Tata McGraw Hill, 2007).
6. Porterfield W.W., Inorganic Chemistry: A Unified Approach, 2ndedn., (Academic Press, 1993).
7. Steed J.W., Atwood J.L., Supramolecular Chemistry, 2ndedn., (Wiley 2009).
Reference Book(s):
1. Adamson A.W., FleischauerP.D., Concepts of Inorganic Photochemistry (John Wiley & Sons, 1975).
2. Beer P.D., Gale P.A., Smith D.K., Supramolecular Chemistry, (Oxford University Press, 1999).
3. Cotton F.A., Wilkinson G., Murillo C.A., Bochmann M., Advanced Inorganic Chemistry, 6thedn. (John
Wiley, 1999).
4. Moeller T., Inorganic Chemistry: A Modern Approach, (John Wiley, 1982).
5. Ratner M., RatnerD., Nanotechnology: A Gentle Introduction to the Next Big Idea, (Pearson Education
2003).
6. RoundhillbD.M., Photochemistry and Photophysics of Metal Complexes, (Plenum Press, 1990).
7. Zhong Cao G., Nanostructures and Nanomaterials: Synthesis, Properties and Applications, (Imperial
College Press, 2004).
E-Resources:
Grading System:

M. Sc. (Chemistry)
BS2210: Heterocyclic Chemistry 4 (3-1-0) Semester-III
Rationale:
Most of the molecules present in biological system and used as medicine are heterocyclic compounds.
Knowledge of their synthesis and reactivity is essential for advanced studies.
This is a course in organic chemistry which will cover synthesis and different types of reaction heterocycles
molecule will undergo. Different heterocyclic present in the biological system is also covered
Pre-requisite:
Basic idea of structure of different heterocycles and their nomenclature is required.
Course Outline:
1.Introduction: (4 Lectures)
Hantzsch-Widman nomenclature for monocyclic, fused and bridged heterocycles; General approaches to
heterocyclic synthesis; Aliphatic and aromatic heterocycles; Basicity and aromaticity of heterocycles.
2. Small ring heterocycles: (5 Lectures)

Syntheses of aziranes, oxiranes&thiiranes; Ring openings and heteroatom extrusion; Synthesis & reactions
of azetidines, oxetanes&thietanes; Strain.
3. Azoles: (5 Lectures)
Structural and chemical properties; Synthesis of pyrazole, isothiazole and isoxazole; Synthesis of
imidazoles, thiazoles&oxazoles; Nucleophilic and electrophilic substitutions; Ring cleavages; Benzofused
analogues.
4. Condensed five-membered rings (1 heteroatom): (5 Lectures)

Synthesis of indole, benzofuran and benzo-thiophene; Nucleophilic, electrophilic and radical substitutions;
Addition reactions; Indole rings in biology.
5. Diazines: (5 Lectures)
Structural & chemical properties; Synthesis of pyridazines, pyrimidines, pyrazines; Nucleophilic and
electrophilic substitutions.
6. Bicyclic heterocycles: (5 lectures)

Synthesis of quinolines, isoquinolines, benzofuseddiazines, acridines, phenothiazines, carbazoles and
pteridines; Substitution reactions.
7. Seven-membered rings: (4 Lectures)

Synthesis & reactions of azepines, oxepines, thiepines&diazepines.
8. Porphyrins:(4 Lectures)
Classification and synthesis of porphin rings; Natural and synthetic metallo- porphyrins; importance in
biology.
9. Biological heterocycles:(5 Lectures)

Chemical and biological properties and total synthesis of thiamine, lysergic acid, reserpine, nicotine,
phenanthrene alkaloids, papaverine, nucleic acids bases.
10. Nucleic acids:(5 Lectures)

Primary, secondary and tertiary structure of DNA; DNA replication and heredity;
Structure and function of mRNA, tRNA and rRNA.
11. Proteins:(3 Lectures)

Acid-base properties of amino acids; polypeptides; primary, secondary, tertiary and quaternary protein
structures; classification of proteins on basis of structure and biological function; Merrifield peptide
synthesis.
Text Book(s):
1. FinarI.L.,Organic Chemistry: Volume2, (ELBS, 1986).
2. Gilchrist T.L.,Heterocyclic Chemistry, (Longman, 1989).
3. LehningerA.L.,Biochemistry, (Kalyani Publishers, 1983).
4. PaquetteL.A.,Modern Heterocyclic Chemistry, (W. A. Benjamin, 1968).
Reference Book(s):
1. Katritzky A.R., ReesC.W.,Comprehensive Heterocyclic Chemistry, Volumes 1-7, (Pergamon Press, 1984).
Journals:
E-Resources:
Grading System:

M. Sc. (Chemistry)
BS2226: Environmental and Green Chemistry 3 (3-0-0) Semester-III
Rationale:
The industrial development has given humankind a unique standard of living and quality of life. However,
this has also exerted a price of environmental degradation. The knowledge of environmental chemistry is
inevitable to make a contribution to the improvement of environmental quality. The goal of this course is to
provide the knowledge of how to do a chemist’s share in improving environmental quality.
On the other hand, green chemistry is a recently developed philosophy of chemical research and engineering
that encourages the design of products and processes that minimize the use and generation of hazardous
substances. It is therefore necessary to provide adequate information to the chemistry student about the
principles and applications of green chemistry.
The overall goal of this paper is to gain an understanding of the fundamental chemical processes that are
central to a range of important environmental problems and to utilize this knowledge in making critical
evaluations of these problems. The program is also designed to provide master level student with a thorough
understandingof principles and applications of green chemistry. The principles and instrumental techniques
of someenvironmental analytical procedures including their applications are also covered in the designed
course.
Pre-requisite:
Basic knowledge of units and their conversions, knowledge of recent environmental problems, basic
knowledge of all branches of chemistry i.e. analytical, inorganic, organic and physical chemistry;
Course Outline:
Part I: Environmental Chemistry

1. Introduction (3 Lectures)
Biotic and abiotic components of environment, macroenvironment and microenvironment, C, O2, N2, P, S,
CO2 etc. cycles, chemical “speciation”.
2. Pollution and its control (17Lectures)

Air pollution –A brief introduction of atmospheric chemistry, types and sources of air pollutants, industrial
and transport related air pollutions, global warming and its effects, local issues.
Water pollution – types and sources, physical and chemical water pollutants, criteria of water quality.
Soil Pollution - A brief idea of chemistry of soil, Organic and inorganic soil pollutants.
Specific Pollutants- Waste materials, trace elements, pesticides and polynuclear aromatic hydrocarbons.
Chemical solutions to environmental problems, better biodegradability, kinetics of decomposition,
chemical- and bio-remediation of contaminated area, phytoremediation.
Examples of pollutions including local environmental issues.
3. Environmental analytical chemistry (4 Lectures)

Trace elements and radionuclide analysis, Analytical procedures involved in environmental monitoring
including brief explanation of instrumental methods, Analysis of soil: moisture, salinity, colloids, cation and
anion exchange capacities of soil,Air pollution monitoring: sampling (collection) of air pollutants-SO2, NO2,
NH3, O3 and SPM.
Part II:Green chemistry (15 Lectures)

Principles of green chemistry, atom economy, designing safer chemicals, safer solvents and auxiliaries,
design for energy efficiency, renewable feedstock, real time analysis for pollution prevention, and
inherently safer chemistry for accident prevention, green synthesis: supercritical solvents, ionic liquids,
green catalyst, clean technology.
Text Book(s):
1. Buell P., GirardJ., Chemistry Fundamentals: An Environmental Perspective, 2ndedn., (Jones & Bartlett
Publishers, 2002).
2. Manahan S.E., Environmental Chemistry, 8thedn., (Lewis Publishers, London, 2004).
3. WillardH.H., Merritt L.L., Dean J.A., Settle F.A., Instrumental Methods of Analysis, 7thedn., (Wadsworth
Publishing Company, California, 1988).
4. Anastas P.T., Warner J.C., Green Chemistry: Theory and Practice, (Oxford University Press, 2000).
5. Lancaster M., Scott J., Wilson, K., Green Chemistry: An Introductory Text, (RSC Publishing, 2010).
Reference Book(s):
1. Moore J.W., Moore E.A., Environmental Chemistry, (Academic Press, London, 1976).
3. Pulford I., FlowersH., Environmental Chemistry at a Glance, (Blackwell Publishing, 2006).
4. Mendham J., Denney R.C., Barnes J.D., Thomas M., Vogel’s Textbook of Quantitative Chemical Analysis
(Peterson Education, 2000).
5. MonkP.M.S., Fundamentals of Electro-analytical Chemistry, (John Wiley & Sons, 2001).
6. Cann, M.C., Connelly M.E., Real World Cases in Green Chemistry, (ACS, 2000).
7. Monograph on Green Chemistry Task Force Experiments, (Chemistry Task Force Committee, DST, New
Delhi, 2008).
8. Ahluwalia V.K., Kidwai M.; New Trends in Green Chemistry, (Kluwer Academic Publishers, 2004).
E-Resources:
1. www.sciencedirect.com
2. www.rsc.com
3. www.springer.com
4. www.acs.com
1. Environmental Science and Technology (http://pubs.acs.org/journal/esthag).
2. ACS Sustainable Chemistry & Engineering (http://pubs.acs.org/journal/ascecg).
3. Green Chemistry (http://pubs.rsc.org/en/journals/journalissues/gc).
4. Environmental Pollution (http://www.journals.elsevier.com/environmental-pollution).
5. Journal of Cleaner Production (http://www.journals.elsevier.com/journal-of-cleaner-production).
6. Environmental Chemistry Letters (link.springer.com/journal/10311).
7. Energy & Environmental Sciences (pubs.rsc.org/en/journals/journalissues/ee).
Grading System:
Elective I
M. Sc. (Chemistry)
BS2212: Natural Product Chemistry 4 (3-1-0) Semester-III
Rationale:
Nature is the source of a large of molecules. Many of them have medicinal values. It is essential to know the
classification, isolation, characterization and structure of natural molecules to do advanced studies.
This is a course in organic chemistry which will cover the classification, isolation, characterization and
biosynthesis of natural products. Synthetic processes for different class of natural products are discussed.
Pre-requisite:
Basic idea of nomenclature and organic reaction mechanism is essential.
Course Outline:
1. Natural products and their biosynthetic pathways: (18 Lectures)

General classification of natural products, their isolation and characterization and biosynthesis of common
plant products; Biosynthesis pathways for natural products using co-enzymes and enzymes; Synthesis of
selected natural products based on genetic classification – fatty acid derivatives and related compounds,
general biogenesis and synthesis of cis-jasmone, methyl jasmonate, prostaglandins, exaltone and muscone.
2.Terpenoids and alkaloids: (18 Lectures)

General biosyntheses of mono- and sesquiterpenes, trans-chrysanthemic acid, cyclo-pentatomonoterpene
lactones, Synthesis of α-vetinone and total synthesis of β-eudesmol; Synthesis of hirsutene, abietic acid,
cisjuvenile hormone; trans annular cyclisation of caryophyllene, synthesis of caryophyllene and
isocaryophyllene; Rearrangements of santonic acid and thujospene; Synthesis and rearrangement of
longifolene; Structure, synthesis and biosynthesis of common alkaloids: reticuline, yohimbine and
tylophorine.
3. Steroids: (14 Lectures)

Biosynthesis of diterpenes, higher terpenes and steroids; Nomenclature of steroids and synthesis of
squalene; Lanosterol and caretonoids; Synthesis of equlenins; Estrogens and total synthesis of non-aromatic
steroids (progesterones); Corticosteroids; Conversion of diosgenin to progesterone and its synthesis;
Miscellaneous transformations of steroid molecules.
Text Book(s):
1.Dewick P.M., Medicinal Natural Products,(John Wiley & Sons Ltd.).
Reference Book(s):
1. NakanashiK.,Natural Products Chemistry, Volumes I and II, (Academic Press, 1974).
E-resources:
2. www.rsc.com
3. www.springer.com
4. www.pubs.acs.com
Journals:
Grading System:
Elective I
M. Sc. (Chemistry)
BS2213:Advanced Organometallic Chemistry 4 (3-1-0) Semester-III
Rationale:
Organometallic chemistry is the study of chemical compounds containing bonds between carbon and a metal.
Thus organometallic chemistry combines aspects of inorganic chemistry and organic chemistry. By
considering the present importance of organometallic chemistry, this course is developedto provide a sound
knowledge of organometallic chemistry, which will help the students for further advanced learning in
organometallic chemistry.
This course contains advanced knowledge and application of organometallic chemistry,Syntheses of some
important organometallic reagents and their applications to organic synthesis and homogeneous catalysis.
Pre-requisite:
Knowledge of organic chemistry, transition and non-transitional metal chemistry and co-ordination chemistry
is essential.
Course Outline:
1. Main group organometallics (14 Lectures)

Synthesis and reactions of organolithium compounds; Synthesis and reactions of organomagnesium
compounds; Organometallics of zinc and mercury: preparation, structure, bonding and reactions of
aluminum organyls; Thallium(I) organyls (synthesis of TlCp); Organyls of sodium, synthesis of NaCp;
Silicon and tin organyls of coordination number 4.
2. Transition metal–carbon bond (12 Lectures)

(a) Transition Metal–Carbon σ-Bond: Brief review of metal alkyl compounds; transition metalcarbene and
transition metal-carbyne compounds; transition metal vinylidene and transition metal allenylidene
compounds.
(b) Transition Metal-Carbon π-Bond: Cyclopropenyl cation (C3R3+) as a ligand; C4R4as a ligand (R = H,
Me, Ph).
3. Syntheses of cyclopentadienyl and arene metal analogues (12 Lectures)

Synthesis and reactions of cyclopentadienyl metal carbonyls, cyclopentadienyl metal hydrides,
cyclopentadienyl metal halides, arene metal carbonyls, η6-arene-chromium tricarbonyl in organic
synthesis.
4. Applications to organic synthesis and homogeneous catalysis (12 Lectures)

(a) In Organic Synthesis: Hydrozirconation of alkenes and alkynes; Carbonylation of Colman’s reagent;
η4-diene iron-tricarbonyls in organic synthesis
(b) In Catalysis: Asymmetric hydrogenation; synthesis of acetic acid and glycol (Monsanto acetic acid
process); Arylation/vinylation of olefins (Heck reaction); Wacker process (olefinoxidation); Asymmetric
epoxidation.
Text Book(s):
1. Cotton F.A., WilkinsonG., Murillo C.A., Bochmann M., Advanced Inorganic Chemistry,5thedn., (Wiley
India, 2003).
2. Crabtree R.H., The Organometallic Chemistry of the Transition Metals, 6thedn., (Wiley,
2014).ElschenbroichC.,Organometallics, 3rdedn., (Wiley-VCH Publication, 2006).
3. Gupta B.D., Elias A.J., Basic Organometallic Chemistry, 2ndedn., (Universities Press, 2013).
5. Mehrotra R.C., SinghA.,Organometallic Chemistry: A Unified Approach, 2ndedn.,(New Age International
Publishers, 2000).
Reference Book(s):
1. BochmannM.,Organometallics-1: Complexes with Transition Metal-Carbon σ-Bonds, (Oxford Chemistry
Primers, 1994).
2. Bochmann M.,Organometallics-2: Complexes with Transition Metal–Carbon π-bonds, (Oxford Chemistry
Primers, 1994).
3. Mathey F.,SevinA.,Molecular Chemistry of the Transition Elements, (John Wiley, 1996).
4. YamamotoA., Organotransition Metal Chemistry: Fundamental Concepts and Applications, (Wiley, 1986).
5. Pearson A.J.,Metallo-Organic Chemistry(John Wiley & Sons, 1985).
E-Resources:
2. www.rsc.com
3. www.springer.com
4. www.pubs.acs.com
5. www.wiley.com
Grading System:
Elective I
M. Sc. (Chemistry)
BS2230: Polymer Chemistry 4 (3-1-0) Semester-III
Rationale:
The knowledge of polymer chemistry is important for its wide application in different polymer material
manufacturing industries and the scope of polymer industry is growing in the North-Eastern corner ofIndia.
Includes Kinetics and mechanism of polymerization, polymerization techniques and characterization,
thermodynamics of polymer solutions, Applications of polymers.
Prerequisite:General physical chemistry principles.
Course Outline:
1. Introduction
Historical background, basic nature, classification, raw materials for polymers used in gas cracker,
naphtha cracker. Kinetics and mechanism of polymerization: Degree of polymerization and molecular
mass of polymer, kinetics of various types of polymerization, copolymerization, reactivity ratio,
molecular mass distribution, control of molecular mass.
2. Polymerization Techniques and Polymer Characterization

Special features of polymerization, various polymerization techniques, polymerization reactions,
Determination of molecular mass by GPC, light scattering, and end group analysis methods. Zimm plot.
Viscosity of polymer solutions: thermal, mechanical, rheological and electrical properties of polymers,
polyelectrolytes and ion-exchange resins.
3. Thermodynamics of Polymer Solutions

Chain conformation, molecular dimensions in solution, solubility of polymers, solubilityparameters,
lattice theory, ΔH, ΔS and ΔG of mixing in polymer solution, dilute polymersolutions, χ1and θ-
temperature, phase separation, fractionation.
4. Structure-Property Relationship
Stereochemistry of polymers, cross-linking, polymer architecture, optically active polymers.
Elasticity, viscoelasticity – Newton, Maxwell and Voigt-Kelvin models of viscoelastic behaviour.
Crystal structure of polymers, crystallization and melting, degree of crystallinity.
5. Natural and Synthetic Polymers and Their Applications

Natural polymers: rubber, natural fibers, silk fibers. Synthetic polymers: HDPE, LDPE, PP, PS, Nylon,
dendrimers etc. Moulding of polymer.Applications and future trends of polymers.
Text Book (s):

1. Gowariker, V.R., Viswanathan, N.V. and Sreedhar, J., Polymer Science, New AgeInternational (2011).
2. Billmeyer, F.W., Textbook of Polymer Science, Wiley India (2010).
Reference book (s):

1. Misra, G.S., Introduction to Polymer Chemistry, New Age International (2008).
2. Flory, P.J., Principles of Polymer Chemistry, Asian Books.
Journals:
E-Resources:
Grading System:
Elective II
M. Sc. (Chemistry)
BS2216: Advanced Topics in Organic Synthesis 4 (3-1-0) Semester-III
Rationale:
The field of chemical synthesis continues to amaze with its growing andimpressive power to construct
increasingly complex and diverse molecular architectures.Being the precise science that it is, this discipline
often extends not only into the realmsof technology, but also into the domains of the fine arts, for it engenders
unparallelpotential for creativity and imagination in its practice. Enterprises in chemical synthesisencompass
both the discovery and development of powerful reactions and the inventionof synthetic strategies for the
construction of defined target molecules, natural ordesigned, more or less complex.Strategic Applications of
Named Reactions in Organic Synthesis is destined to become unusually useful, valuable, and influential for
advanced students and researchers in the field.
This is a course in organic chemistry which will cover the discussion of a number of name reactions, their
mechanisms in detail and the strategic application in an advanced level.
Pre-requisite:
Basic idea of organic name reaction and disconnection approach.
Course Outline:
1. Reaction, mechanism and applications (17 Lectures)
(a) Nucleophilic C-C bond formation:Henry reaction, Wittig reaction and Horner-Wordwoth-Emmons
reaction and their selectivities,chemistry of enolates:E,Zgeometry of enolates, kinetic vs. thermodynamic
control of enolates, stereoselectiveenolate reactions, alkylation, aldol condensation (Zimmerman and Evans
models), mukaiyama reaction.
(b) Electrophilic C-C bond formation: Nazarov cyclization, prins reaction, Vilsmeier-Hack reaction, Pictet-
Sprengler reaction, reactions of π-allyl palladium complexes, Heck reaction, Stille coupling, Noyori
reaction,Suzuki coupling, Neigishi Coupling, Chan-Lam Coupling reactions of allylsilane.
(c) Miscellaneous reactions: Biginelli reaction, Hantzsch reaction, Passerini reaction, Ugi reaction,
McMurryolefination, ring closing metathesis (RCM): Grubb’s reaction, Mitsonobu reaction, Nef reaction,
Sharpless asymmetric epoxidation and asymmetric dihydroxylation, Julia olefination.
2. Reagents in organic synthesis (17 Lectures)
Use of following reagents/reactions in organic synthesis and functional group transformations: K-
selecteride and L-selecteride, sodium cyanoborohydride, super hydrides, 9-BBN, IBX, Dess-Martin
periodinane, manganese dioxide, Fetizon reagent, dioxiranes, ceric ammonium nitrate,Gilman’s reagent,
lithium disopropylamide, dicyclohexylcarbodimide, trimethysilyliodide, trin-butyltin hydride, Tebbe
reagent, Corey-Nicolaou reagent, Peterson’s synthesis, baker’s yeast, lipase, Mosher’s reagent, use of Os,
Ru, and Tl reagents and DDQ.
3. Disconnection approach (14 Lectures)
Synthons and synthetic equivalents, disconnection approach, functional group inter-conversions,
importance of order of events in organic synthesis, one group and two group C-X disconnections,
chemoselectivity, reversal of polarity, cyclisation reactions, amine synthesis, one group C-C
disconnections: alcohols and carbonyl compounds, regioselectiviity, alkene synthesis, use of acetylenes
and aliphatic nitro compounds in organic synthesis, two group C-C disconnections: Diels-Alder reaction,
1,3-difunctionalised compounds, α,β-unsaturated carbonyl compounds, control in carbonyl
condensations, 1,5-difunctionalised compounds, Michael addition and Robinson annelation,principle
of protection of alcohol, amine, carbonyl and carboxyl groups, Common protecting groups,
retrosynthetic analysis, synthesis of quercetin, pinene, camphor and emetine.
Text Book(s):
1. Carey F.A., Sundberg R.J.,Advanced Organic Chemistry,Part B, (Plenum Press, 2007).
2. KalsiP.S., Organic Synthesis through Disconnection Approach, 1stedn., (Medtec, India, 2014).
3. MarchJ., Advanced Organic Chemistry: Reactions, Mechanism and Structure, 4thedn.,(John Wiley & Sons,
2005).
4. SmithM.B.,Organic Synthesis, 2ndedn.,(McGraw-Hill Inc., 2001).
5. Warren S., WyattP., Organic Synthesis: The Disconnection Approach, 2nd edition, (Wiley, 2008).
Reference Book(s):
1. CarruthersW.,Some Modern Methods of Organic Synthesis,4thedn.,(Cambridge University Press, 2004).
2. TrostB.M., FlemingI.,Comprehensive Organic Synthesis, Volumes. 1-9, (Pergamon, 1991).
E-resources:
2. www.rsc.com
3. www.springer.com
4. www.acs.com
Journals:
Grading System:
Academic Council Approval

Elective II
M. Sc. (Chemistry)
BS2225: Bioinorganic Chemistry 4 (3-1-0) Semester-III
Rationale:
Bioinorganic chemistry is a scientific discipline spanning the field of inorganic chemistry and biology.
Knowledge of bioinorganic chemistry will help students to understand the role of various inorganic
elements on the various bio-chemical processes.
Basic to advanced knowledge of bioinorganic chemistry.
Pre-requisite:
Basic knowledge of cell biology, protein chemistry, nucleic acids chemistry, carbohydrate chemistry, enzyme
kinetics, toxicological chemistry.
Course Outline:
1. Metal Storage Processes (10 Lectures)

Transition-metal storage, transport and bio-mineralization: Biological significance of transition-metals,
chemical properties relative to storage and transport, biological systems of metal storage, transport and
(bio-) mineralization, recent development.
2. Calcium in Biology (10 Lectures)

Calcium in living cells, transport and regulation, molecular aspects of intramolecular processes,
extracellular binding protiens.Role in muscle contraction, blood clotting mechanism and biological
calcification, recent development.
3.Protiens and Enzymes of Transition Elements (16 Lectures)

Hemerythrin, ferritin and transferrins, peroxidase, catalase, cytochrome P-450. Iron – sulphur proteins:
rubredoxin and ferredoxins. Cytochrome C oxidase and superoxide dismutase, ceruloplasmin, Vitamin
B12, B12 co-enzymes and cobalamines, carbonic anhydrase, carboxy peptidase, metallothionins,
interchangeability of Zn and Co in enzymes. Structural and functional models.Biological nitrogen fixation,
photosynthesis, Photosystem I and II in cleavage of water, recent development in these fields.
4. Metals in Medicine(12 Lectures)

Toxicity of mercury, cadmium, lead, chromium, beryllium, selenium and arsenic, biological defence
mechanisms, chelation therapy, metals used for diagnosis and chemotherapy, platinum complexes as
anticancer drugs, complexes of gold, copper, zinc, mercury, arsenic and antimony as drugs, recent
development in these fields.
Text Book(s)
1. Bertini I., Gray H.B., Stiefel E.I., Valentine J.S.,Biological Inorganic Chemistry: Structure and Reactivity,
(University Science Books, US, 2006).
2. Cowan, J. A. Inorganic Biochemistry- An Introduction, (Wiley- VCH, 1997).
3. Hanzlik, R. P. Inorganic Aspects of Biological and Organic Chemistry, (Academic Press, 1976).
Reference Book(s)
1. Rehder D., Bioinorganic Chemistry, (OUP, Oxford, 2014).
2. Lippard, S. J., Berg, J. M. Principles of Bioinorganic Chemistry, (University Science Book, Mill Valley,
1994).
3. Hay, R. W. Bioinorganic Chemistry, (Ellis Hollwood, 1984).
E-Resources:
Grading System:
Elective II
M. Sc. (Chemistry)
BS2242:Catalysis and Surface Chemistry 4 (3-1-0) Semester-III
Rationale:
The course on catalysis isidentified as not only of appliedimportance in general, but also of particular
relevance to the North-Eastern corner ofIndia, since this region is rich in petroleum and bio-diversity.
Moreover the course on surface phenomena is provided due to its wide scope in industry and research and
development. It brings physicists, chemist, electronics engineers, and material engineers to the same platform
giving a complete interdisciplinary approach towards a problem and solution.
Includes mechanism of catalysis, catalyst types, characterization, theories involved in catalysis to its wide
industrial applications. This course also covers the surfaces and interfaces, types, properties, different forces
of attractions surfactants and its applications.
Prerequisite: BS2203
Course Outline:
1. Introduction (7Lectures)
Definition, role of catalysts, classification of catalysts,
Surfaces and interfaces, characteristic features of surfactants, general structural features & behavior of
surfactants, hydrophobic/solvophobic interaction,adsorption of surfactants at interfaces, solid liquid, gas-
liquid and liquid-liquid interfaces.
Characterization of catalysts and their surfaces: Methods of surface analysis, surface area, pore size, void
fraction, particle size, mechanical strength, surface chemical composition, surface acidity and reactivity,
environmental aspect.
2. Surfactants and surface phenomena(10 Lectures)

Classification of surfactants, micelles, critical micelle concentration, Kraft point,cloud point, micellar
structure and shape, aggregation number, thermodynamics of micellisation, mixed micelles, HLB,
biological membrane, reversed micelle, self assembly of nanostructures, micellar catalysis, Interfacial
rheology, solubilisation, wetting, foaming, dispersion, emulsification and applications. Structure of
surfaces, thermodynamics of surfaces, dynamics at surfaces, physico-chemical properties of surfaces,
physical processes at interfaces, surface properties.
3. Homogeneous catalysis (4Lectures)

Mechanism of homogeneous catalysis, acid-base catalysis, enzyme catalysis, micellar catalysis, phase
transfer catalysts, homogeneous catalysis in industry, Zigler-Natta catalysts.
4. Heterogeneous catalysis (15Lectures)

Adsorption and catalysis, mechanism of heterogeneous catalysis, kinetics of heterogeneous catalytic
reactions, volcano principle,
Production and design of industrial catalysts: materials and methods, precipitated catalysts, impregnated
catalysts, skeletal catalysts, fused and molten catalysts, calcination, reduction, shape formation of catalyst
particles, Catalytic reactors.
Examples of heterogeneous catalysts: clays, zeolites, bimetallic, semiconductor and oxide catalysts,
supported catalysts, polymer catalysts, catalytic processes in petroleum industry reforming, cracking and
hydrotreating; hydrogenation, hydrodesulphurization, Fischer-Tropsch process, etc.
Promotion and promoters, causes and mechanism of deactivation, poisoning, sintering, prevention of
catalyst decay, regeneration of catalysts.
Text Book(s):
1. Bartholomew C.H., Furrauto R.J.,Fundamentals of Industrial Catalytic Processes 2ndedn.,(Wiley
Interscience, 2006).
2. Rosen M.J., Surfactants and Interfacial Phenomena (John Wiley, 2004)
2. Chakrabarty D.K., Viswanathan B.,Heterogeneous Catalysis (New Age Int., 2008).
3. Bond G. C., Heterogeneous Catalysis: Principle and Application; Clarendon Publisher, (1987).
4. Viswanathan B.; Kannan, S.; Deka, R. C., Catalysts and Surfaces Characterization
Techniques, Narosa Publishers (2010).
Reference Book(s):
1. Augustine R.L., Heterogeneous Catalysts for Synthetic Chemists, (Marcel-Dekker, 1996).
2. Gates B.C., Catalytic Chemistry, (John Wiley & Sons, 1992).
3. Wijngaarden R.J., Industrial Catalysis, (Wiley-VCH, 1998).
4. Thomas, J. M.; Thomas, W. J., Principle and Practice of Heterogeneous Catalysis, Wiley VCH
(1996).
Journals:
E-Resources:
Grading System:

M. Sc. (Chemistry)
BS2241: Physical Chemistry Laboratory 6 (0-0-12) Semester III
Rationale:
This course has included different analytical methodologies, which will help students’ analytical skill to
undertake academic and industrial research work.
Pre-requisite:
Basic experimental skills, basic concept of chemistry, safety rules in chemical laboratory.
Course Outline:
(At least 10 experiments to be done)

1. To estimate the concentration of HCl, acetic acid, copper sulphate by conductometric method.
2. To study the reaction rate of hydrogen peroxide and HI and determine the energy of activation.
3. To determine the ionization constant of acetic acid by conductometric method
4. To determine the hydrolysis constant of aniline hydrofluoride by conductometric method.
5. To find the stability constant of coordination compound formed between Cu2+ and 5-sulpho salycilic acid.
6. To establish the order of the reaction of potassium oxalate and mercuric chloride by ratio variation method.
7. To determine the stability constant of an indicator(methyl red)
8. To evaluate the formation constant between iodine and pyridine by determining the isobastic point
9. To estimate the mixture of HCl, NaCl and NH4Cl conductometrically
10. To study the catalytic composition of H2O2.
11. To study the formation constant of FeSCN at ionic strength of one.
12. Determination of viscosity and shear viscosity of polymer solution, microemulsion and gels by using
various types of viscometers.
13. Study of redox reactions, determination of half-wave potential and quantitative determination of metal
ions by polarometry and cyclic voltammetry.
14. Determination of molecular weight by different techniques.
15. Determination of flash point and pour point.
NB: Any other experiments depending upon availability of analytical instruments in the laboratory.
Text Book(s):
1. Viswanathan B., Raghavan P.S.,Practical Physical Chemistry (Viva Books Pvt. Ltd., 2005).
Reference Book(s):
1. James A.M., Prichard F.E.,Practical Physical Chemistry (Longman, 1974).
2. Levitt B.P.,Findley’s Practical Physical Chemistry (Longman, 1973).
E-resources:
2. www.rsc.com
3. www.springer.com
4. www.pubs.acs.com
Journals:
Grading System:

SEMESTER IV
M. Sc. (Chemistry)
BS2227: Research Methodology and Analytical Techniques 3 (3-0-0)Semester IV
Rationale:
To provide a strong base to a students who opt to become a researcher in his field. New “add on” which can
enhance value, in a global value chain and new generic or specific items(s), which can be the front end of new
knowledge. To enhance the choice of specific subjects, detailed action plan, milestones, regular review of the
current knowledge in the subject.
It covers planning a research program from the available knowledge, the potential for making an original
contribution to the literature in the field,the research implications and construct a research proposal and present
in the form of synopsis and seminar. The theory and applications of various instrumental methods, used in
R&D works are also included.
Pre-requisite:
Knowledge of common laboratory techniques along withbasic conceptions of chemistry, mathematics and
physics.
Course Outline:
1. Research methodology (8 Lectures)
Meaning and objectives of research, nature and significance of research, criteria of good research, ethics
in research, formulating the research problem, literature survey,understanding scientific papers, preparing
the research design, collection of data, project execution, analysis of data, hypothesis testing using
statistical analyses, generalization and interpretation, plausible research implications.
Publication from research: types of publications, research paper and technical report
preparations,presentation in seminar: oral and poster, application for patent, types of patent.
Computers in research: computers and researchers, online literature collections, Latex, software’s used in
research.
2. Laboratory safety issues (2 Lectures)
Laboratory safety issues: lab, workshop, electrical, health and fire safety, safe disposal of hazardous
materials.
3. Errors in analysis and analytical data treatment (4 Lectures)
Errors, determinant, constant and indeterminate, Accuracy and precision, distribution of random errors,
average and standard deviation, variance and confidence limit, significance figures and computation rules,
least square method, correlation coefficient and its determination,use of spread sheets for plotting
calibration curves, quality assurance and control charts.
4. Sampling in research (2Lectures)
Sampling techniques: gas, liquid and solid, crushing and grinding, the gross sampling, preparation of a
laboratory sample, moisture in samples-essential and non-essential water, absorbed and occluded water,
determination of water (direct and indirect methods),decomposition and dissolution, sources of error.
5. Instrumental analysis (20 Lectures)

Applications of instruments in analysis including basic theory and examples: thermal analysis, X-ray
diffraction (XRD) techniques, X-ray fluorescence (XRF), infra-red (IR)/Fourier transform IR (FTIR)
spectroscopic techniques, AAS and ICP analytical techniques, chromatography, electroanalytical
methods, magnetic resonance techniques (NMR etc.), scanning electron microscopic technique, energy
dispersive X-ray analysis, vacuum techniques, temperature measurement, radiation detectors.
Techniques of analysis of nano-materials: transmission electron microscopy, atomic force microscopy,
impedence spectroscopy, nano scale impedence microscopy (NIM).
Text Book(s):
1. Kothari C.R., Research Methodology, 2nd edition (New Age International (P) Limited Publishers, 2004).
2. Day R.A., Underwood A.L., Quantitative Analysis, 6thedn., (Prentice Hall, 1991).
3. Khopker S.M., Basic Concepts of Analytical Chemistry, 3rd Edition, (New Age Science, 2008).
Reference Book(s):
1. Hawkins C., Sorgi M.,(edtd.) Research How to Plan, Speak and Write about It, (Narosa Publishing House,
1993).
2. Manahan S.E., Environmental Chemistry, 9thedn., (CRC Press, 2010).
3. Vogel A.I., A Textbook of Practical Organic Chemistry, (Longman, 1974).
4. Mendham, J.; Danney, R.C.; Barnes, J.D.; Thomas, M. Vogel’s Textbook of Quantitative Chemical
Analysis, (Peterson Education, 2000).
5. Khopker S.M., Basic Concepts of Analytical Chemistry, 3rd Edition, (New Age Science, 2008).
6. Mermet J.M., Otto M., Kellner R., Analytical Chemistry, (Wiley-VCH, 2004).
7. Skoog D.A., West D.M., Holler F.J., Crouch S.R., Fundamentals of Analytical Chemistry, 8thedn.,
(Saunders College Publishing, 2007).
8. Kennedy J.H., Analytical Chemistry: Principles, (Saunders College Publishing, 1990).
9. Dick J.G., Analytical Chemistry, (R.E. Krieger Publishing, 1978).
10. Wilson C.L., Wilson D.W., Comprehensive Analytical Chemistry, (Elsevier, 1982).
11. Christian G.D., O’Reilly J.E., Instrumental Analysis, (Allyn&Bacon, 1986).
12. Pradeep T., Nano: the Essentials, (Tata McGraw Hill, 2007).
13. Kolasinski K.W., Surface Science: Foundations of Catalysis and Nanoscience, 2nd edn., (Wiley, 2009).
E-resources:
2. www.rsc.com
3. www.springer.com
4. www.pubs.acs.com
5. www.wiley.com
Grading System:

Elective III
M. Sc. (Chemistry)
BS2219: Medicinal Chemistry 4 (3-1-0) Semester IV
Rationale:
To provide a background of medicinal chemistry which will help to work in drug discovery research.
It covers fundamental topics related to drug development .Synthesis and activity of antibiotics and type I and
Type II is discussed.
Pre-requisite:
Basicconcepts of chemical biology is required.
Course Outline:
1. Introduction: (14 Lectures)

Concept of drug, pro-drugs and soft drugs, lead compound and lead modification,structure
activityrelationship (SAR), quantitative structure-activity relationship (QSAR),factors affecting
bioactivity: resonance, inductive effect, isosterism, bio-isosterism, spatialconsiderations,physicochemical
parameters:lipophilicity, partition coefficient, electronic ionization constants, steric, shelton and surface
activity parameters and redox potentials,concept of drug receptors : elementary treatment of drug-
receptor interactions,theories of drug activity : occupancy theory, rate theory, induced fit theory: factors
affecting modes of drugadministration, absorption, metabolism and elimination.
2. Antibiotics: (12 Lectures)

Cell wall biosynthesis, inhibitors of β-lactam rings, antibiotics inhibiting protein synthesis, isolation,
structure elucidation, synthesis, SAR and mode of action of penicillins,synthesis of penicillin G, penicillin
V, ampicillin, amoxicillin and cephalosporin, isolations and structures elucidation, synthesis, SAR and
mode of action of following antibiotics: streptomycin, tetracyclines and chloroamphanicol.
3.Drug Types – I: (12 Lectures)

(a) Antineoplastic drugs: Cancer chemotherapy, role of alkylating agents and antimetabolites inthe
treatment of cancer,carcinolytic antibiotics and mitotic inhibitors, synthesis of echlorethamine,melphalan,
5-bromouracil and 6-mercaptopurine,anticancer action of cisplatin andtaxol.
(b) Cardiovascular drug: Classification, synthesis and mode of action of quinidine, verapamil,methyldopa
and buphenine.
(c) Hypnotics and sedatives: SAR and mode of action; Synthesis of diazepam, oxazepam,
chlorazepam,alprazolam, barbiturates, thiopental sodium.
(d) Local anaesthetics: Classification, SAR and mode of action; Synthesis of procaine, α-eucaineand β-
eucaine, xylocaine, cinchocaine and quinisocaine.
4. Drug Types –II : (12 Lectures)

(a) Antiinfective drugs: Mode of action and synthesis of sulphonamides, furazolidone,
ciprofloxacin,norfloxacin, daspone, isoniazide.
(b) Antipyretic Analgesics: Classification and mode of action of antipyretic analgesics;Synthesis of
paracetamol, chincophan, Novalgin and mefenamic acid.
(c) Antihistamines: SAR and mode of action of H1-receptor antagonists; Synthesis ofbromazine,
mepyramine, methapyriline, antazoline, promethazine and phenindamine.
(d) Antimalarial drug: Nitrogen heterocycles as antimalarial agents, their classification andmode of action,
synthesis of chloroquine, pamaquine, primaquine, Mepacrine andpyrimethamine. Introductory idea on
Artemisinin, artemether and arteether.
Text Book(s):
1.Brunton L., Lazo J., Parker K., Goodman’s & Gilman’s, The Pharmacological Basis of Therapeutics,
(McGraw-Hill, 2005).
2. LednicerD.,Strategies for Organic Drug Synthesis and Design, (John Wiley, 1998).
3. PandeyaS.S.,Dimmock J.R., Introduction to Drug Design, (New Age International, 2000).
4. Patrick G.L., Introduction to Medicinal Chemistry, 3rdedn., (OUP, 2005).
5. Wolff M.E. (ed.), Burger’sMedicinal Chemistry and Drug Discovery, Volume-1, (John Wiley, 1994).
Reference Book(s):
E-resources:
2. www.rsc.com
3. www.springer.com
4. www.pubs.acs.com
Journals:
Grading System:
Elective III
M.Sc. (Chemistry)
BS2221: Chemistry of Materials 4 (3-1-0) Semester- IV
Rationale:
The Physics and Chemistry of Materials provides the background information necessary to assimilate the
current academic and patent literature on materials and their applications. The course focuses on the most
technologically important materials being utilized and developed by scientists and engineers.
It coversstructure of materials, physical properties of materials, including electrical, thermal, optical,
magnetic, and mechanical properties, A section on surfaces, thin films and interfaces.
Prerequisite: None.
Course outline
1. Glasses, ceramics, compositesandnanomaterials (8 Lectures)
Glassystate,glassformers and glass modifiers, applications,Ceramicstructures,mechanical properties, clay
products, refractories,characterization, propertiesandapplications.
Microscopiccomposites, dispersion strengthened andparticle-reinforced,fibre-reinforced composites,
macroscopic composites, nanocrystalline phase, preparation procedures, specialproperties, applications.
2. Thinfilms and Langmuir-Blodgettfilms (8 Lectures)
Preparationtechniques, evaporation/sputtering, chemical processes, MOCVD, sol-gel, etc.Langmuir-
Blodgett(LB)film, growthtechniques, photolithography, properties and applications of thinandLBfilms.
3. Liquid c rystals (6 Lectures)
Nomatic, smectic, cholesteric – properties and applications.
4. Polymeric materials (6 Lectures)
Molecular shape, structure and configuration, crystallinity, stress-strain behaviour, thermal behaviour,
polymer types and their applications, conducting and ferro-electric properties.
5. Ionicconductors (7 Lectures)
Typesofionicconductors, mechanism ofionicconduction, interstitial types(Frenkel);vacancymechanism,
diffusion superionicconductors; phase transitions and mechanism of conduction insuper ionic conductors,
examples and applications of ionicconductors.
6. HighTcmaterials (5 Lectures)
Defectperovskites, highTcsuperconductivity incuprates, preparation andcharacterizationof1-2-3 and 2-1-
4 materials, normal state properties; anisotropy; temperature dependence of electrical resistance, optical
phonon modes, superconducting state,heat capacity; coherence length, elastic constants, position lifetimes,
microwave absorption-payingandmulti gap structure inhigh Tcmaterials, applicationsofhighTcmaterials.
7. Materialsfor solid-state devices (2 Lectures)
Rectifiers, transistors, capacitors IV-V compounds, low-
dimensionalquantumstructures;opticalproperties.
8. Organic solids, fullerenes, molecular devices (2 Lectures)
Conducting organics, organicsuperconductors,magnetisminorganicmaterials,
dopedfullerenesassuperconductors.
9. Molecular devices (3 Lectures)
Molecular rectifiers and transistors, artificial photosynthetic devices, optical storage
memoryandswitches -sensors.
10. Nonlinear opticalmaterials (3 Lectures)
Nonlinearopticaleffects,second a nd third order-molecular hyper polarizabilityand
secondorder electricsusceptibility-materialsforsecondand t hi r d harmonicgeneration.
Text Book(s):
1. Ashcroft N.W., Mermin N.D., Solid State Physics (Saunders College, 1993).
2. Keer H.V., Principles of the Solid State (Wiley Eastern, 1993).
Reference Book(s):
1. Callister W.D., Material Science and Engineering- An Introduction (Wiley, New York, 1985).
2. Lever K.D., Alexender J.M., Rawlings R.D., Materials Science (J.C. Senderson, ELBS).
3. Marck J.E., Allcock H.R., West R., Inorganic Polymers (Prentice Hall, 1992).
Journals:
E-Resources:
Grading System:
Elective III
M. Sc. (Chemistry)
BS2224:Industrial Chemistry 4 (3-1-0) Semester-IV

Rationale:
Industrial chemistry deals with commercial production of chemicals and related products from natural raw
materials and their derivatives. The goal of studying industrial chemistry at university is to try and bridge the
gap between classical chemistry and chemistry, which is applied in industry.
The program is designed to provide master level student with a thorough understandingof industrial materials
and processes with special emphasize on those relevant to northeast India;
Pre-requisite:
Basics of chemistry and environmental science, knowledge of ores, minerals and natural resources of northeast
India
Course Outline:
1. Energy Sources (16 Lectures)

Coal and biomass: Renewable and non-renewable fuel sources, origin and classification of coal,
desulphurization, production of coal chemicals, Biomass as energy sources, gasification of coal, biomass
and coal-biomass, thermokinetics.
Petroleum and petrochemicals: Origin and history of petroleum, methods in petroleum exploration,
reservoir conditions, oil field waters, secondary enhanced oil recovery, instrumental methods used in
petroleum explorations, drilling fluid, oil-field chemicals, transportation of petroleum,refining of
petroleum, composition of petroleum, hydro-treating, cracking of oil, reforming, isomerization, unleaded
oil, petrochemicals, cracking of natural gas, natural gas as a fuel.
Other energy sources: H2 gas and its preparation methods, nuclear energy, fuel cells, hybrid cells.
2. Silicate industries (4 Lectures)

Cement, glass and ceramics: Chemical and mineral composition of cements, clinkerization process,
various grades of cement, analysis and testing of cement, production and uses of gypsum, glass:
composition and chemistry of glass productions, types of glasses, glass-ceramics, silicate based ceramic
industries: basic raw materials, basic ceramic chemistry and ceramic products.
3. Inorganic chemical industries (15 Lectures)

Fertilizer: Essential plant nutrients and their functions, raw materials and process, productions of: super
phosphates, phosphoric acids, synthetic ammonia, urea, potassium nitrate, biofertilizers.
Sulfur and sulfuric acid: Sources of sulfur and mining, sulfur from fuel gases, production of sulfuric acid
by contact process, recovery of used sulfuric acid.
Iron and steel:Various grades of products.
Chloro-alkali industry: Manufacture of soda ash, chlorine and caustic soda, cell types including fuel cells,
bleaching powder, calcium and sodium hypochlorite..
Electrochemical industry: Production of Al, Mg, and Na by elecrochemical process, primary and
secondary cells.
Industrial gases:Manufacturing and industrial uses of H2, O2, N2, CO2, Cl2 and acetylene gases,
liquefaction of gases, production of low temperature.
Pulp & paper industry: Raw materials, methods of pulping, paper production processes, cellulosic
products: natural fiber production and processing.
4. Organic chemical industries (10 Lectures)

Dyes, detergents and soaps:Raw materials and processing, dyeing, raw materials for detergents
productions, specification and detergency, synthetic glycerin.
Agrochemicals: Production of ethanol and methanol, chemicals for improving production of crops,
chemicals from woods.
Pharmaceutical industry: Chemistry involved in the production of some important pharmaceuticals.
Fats, waxes and oils: Extraction and processing of oils and fats, fat hardening, types of wax.
Polymers and rubbers:Synthetic and natural rubbers, compounding and fabrication of rubber, raw
materials of polymer, polymer processing and fabrication.
Surface coating industries: Various types of paints, pigments, varnishes.
5. Materials in electronic industries (5Lectures)

Recent trends in sensor technology, types of sensors, applications of sensors, semiconductor IC technology,
high purity silicon, germanium, gallium arsenide (GaAs),indium phosphide (InP), etc. preparations,
crystalgrowth and there use in electronic industry,high temperature materials, high alumina, alumina, SiC,
chromite, zirconia, magnesite etc.,ionic &superionic conductors, β-alumina oxide ion conductors, halide
conductors.
Text Book(s):
1. Gesser H.D., Applied Chemistry: A Textbook for Engineers and Technologist, 1st edition, (Springer, 2008).
2. Austin G.T., Shreve’s Chemical Process Industries, 5th edition, (Tata McGraw-Hill, 2012).
3. Heaton A.,The Chemical industry, 2ndedition (Blackie Academic, 1996).
4. Thompson R. (Ed.) Industrial inorganic chemicals: production and uses (Royal Society of Chemistry,
1995).
Reference Book(s):
1. BhaskaraRao B.K., Modern Petroleum Refining Processes, 5th edition, (Oxford & IBH Publishing Co Pvt.
Ltd., 2010).
2. Satyanarayana D., Petroleum Geochemistry, 1st edition (Daya Publishing House, 2011).
3. Kent J.A., Handbook of Industrial Chemistry (McGraw-Hill, 2004).
4. Speight J.G., The chemistry and Technology of Petroleum (Dekker, 1999).
5. Dawe R.A., Lucas A.G. (edtd.), Modern Petroleum Technology, Volume 1: Upstream, Volume 2:
Downstream (John Wiley, 1990).
6. Patranabis D., Sensors and Transdusers, 2ndedition (Prentice, Hall of India, 2003).
7. BalsubramaniamR.,Callister'sMaterials Science and Engineering, (John Wiley & Sons, 2009).
8. West A.R., Solid State Chemistry and Its Applications, (John Wiley & Sons, 2003).
E-Resources:
Grading System:

M. Sc. (Chemistry)
BS2237:Dissertation10 (0-0-20) Semester IV

Rationale:
To provide a strong base to students to study the advanced chemistry.To enhance the choice of specific
subjects, detailed action plan and execution of planned work, to understand how to analyze the experimental
results and how to prepare dissertation/publications on his/her work.
It covers the experimental planning ofthe proposed research program in chemistry from the available
knowledge, the potential for making an original contribution to the literature in the field,the research
implications and preparing the research outputs, execution of planned experimental work on his topic and
analysis of thus obtained results, dissemination of the results in the form of a thesis and presentation of his
finding in seminar.
Pre-requisite:
Basicconceptions of chemistry, physico-chemical processes involved in reactions, reagents and knowledge of
chemistry laboratory techniques including separation, preparation and isolation of pure
molecules.Conceptions of mathematics and physics will also be needed.
Course Outline:
1. Preparation of research synopsis:

In the final semester, students have to carry out research work at Kaziranga University or specified
organization. The area of the work is to be decided by the advisor. Before starting of the project work,
students have to submit the work-plan in the form of a synopsis followed by oral presentation in the
presence of faculty members and external expert(s).
2. Research project
After preparation and approval of the synopsis, students have to carry out research work at Kaziranga
University or specified organization. The area of the work is to be decided by the advisor. On completion
of the project work, students have to submit the work in the form of a dissertation followed by oral
presentation in the presence of faculty members and external expert(s).
3. Testing
The student will be tested both in subject matter and the mode of presentation.
The components in the subject matter include
1. Standard of subject and plan
2. Preparation and mastery
3. Originality and logical development
4. Answers to question
5. Summary and references
The components in the mode of presentation include
1. Economy of time
2. Voice as a tool of communication
3. Blackboard use and teaching aids
4. Language and diction
5. Relating to the audience
Text Book(s):
No definite textbooks are available. Representative thesis of different universities may be consulted.
Reference Book(s):
Text books ofspecialized areas may be referred
E-resources:
2. www.rsc.com
3. www.springer.com
4. www.pubs.acs.com
Journals:
Grading System:
*** ** ***

Syllabus For Master of Science in Chemistry: The Assam Kaziranga University, Jorhat

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Syllabus For Master of Science in Chemistry: The Assam Kaziranga University, Jorhat

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THE ASSAM KAZIRANGA UNIVERSITY, JORHAT

SCHOOL OF BASIC SCIENCES

1. Periodic properties and bonding (24 Lectures)

2. Oxidation and reduction reactions (5 Lectures)

3. Acids and bases: (5 Lectures)

4. Aspects of d- and f-block elements (14 Lectures)

Journals and Magazines:

The Assam Kaziranga University

BS2202: Stereochemistry and Principles of Organic Synthesis4 (3-1- 0) Semester I

1. Stereochemistry: (12 Lectures)

4. Elimination reactions: (5 Lectures)

5. Addition to carbon-carbon multiple bonds: (5 Lectures)

6. Carbonyl and related groups: (6 Lectures)

7. Photochemical reaction: (4 Lectures)

Journals and Magazines:

Academic Council Approval:

BS2222: Principles of Physical Chemistry 4 (3-1-0) Semester I

Rationale:The objective is to make the concepts of thermodynamics, quantum chemistry and

1. Equilibrium thermodynamics (12Lectures)

2. Non-Equilibrium thermodynamics (5 9Lectures)

3. Statistical thermodynamics (5 9Lectures)

5. Bio-physical chemistry (5 11 Lectures)

Journals and Magazines:

Academic Council Approval:

The Assam Kaziranga University

BS2211: Quantum and Computational Chemistry 4 (3-1-0)Semester-I

1. Fundamental principles and applications to simple systems (16Lectures)

2. Atomic structure (28Lectures)

3. Computational chemistry (6Lectures)

Academic Council Approval:

The Assam Kaziranga University

B. Synthesis and characterization of inorganic compounds

Journals and Magazines:

Academic Council Approval:

1. Bonding in transition metal complexes (11 Lectures)

6. Kinetics and mechanism of inorganic reactions (11 Lectures)

Journals and Magazines:

Academic Council Approval:

The Assam Kaziranga University

1. Reduction reactions: (14 Lectures)

2. Oxidation reactions: (14 Lectures)

3. Reactive intermediates: (14 Lectures)

4. Disconnection approach: (8 Lectures)

Journals and Magazines:

Academic Council Approval:

The Assam Kaziranga University

BS2207: Chemical Dynamics and Electrochemistry 4 (3-1-0) Semester II

Pre-requisite:Strong background in chemistry at the degree level. Knowledge of mathematics is required.

1. Chemical dynamics (25 30Lectures)

Homogeneous and heterogeneous catalysis, enzyme catalysis, phase transfer catalysis.

2. Electrochemistry: (15 20Lectures)

Journals and Magazines:

Academic Council Approval:

The Assam Kaziranga University

1. Chemical applications of group theory (16Lectures)

2. Rotational and vibrational spectra (7 Lectures)

3. Electronic spectra (5 Lectures)

4. Mass spectrometry (6 Lectures)

5. Nuclear magnetic resonance (NMR) spectroscopy(13 Lectures)

6. 13C NMR spectroscopy (3 Lectures)

Journals and Magazines:

Academic Council Approval:

BS2229: Organometallic and Bioinorganic Chemistry 3 (3-0-0) Semester-II