Escolar Documentos
Profissional Documentos
Cultura Documentos
1990-95
Year
Organ 1990 1991 1992 1993 1994 1995
Kidney 9880 10122 10230 11021 11392 11807
Liver 2690 2953 3064 3457 3652 3923
Heart 208 2125 2171 2297 2340 2361
Lung 203 405 535 666 723 871
Totals 14881 15605 16000 17441 18107 18962
SOURCE: Compiled from United Network for Organ Sharing web site, 1996.
Year
Organ 1990 1991 1992 1993 1994 1995
Kidney 6404 6657 6811 7455 7749 8094
Liver 2886 3189 3368 3800 4154 4357
Heart 2181 2202 2248 2444 2529 2506
Lung 276 399 527 802 945 940
Totals 5684 5880 6085 6514 6777 7223
SOURCE: Compiled from United Network for Organ Sharing web site, 1996.
Exhibit 4 Organ Procurement and Transplantation Network Waiting Lists, U.S. 1990-95
Year
Organ 1990 1991 1992 1993 1994 1995
Kidney 17883 19352 22376 24973 28498 31045
Liver 1237 1676 2323 2997 4059 5691
Heart 1788 2267 2690 2834 2933 3468
Lung 308 670 942 140 1625 1923
Totals 21216 23965 28331 30944 37115 42127
SOURCE: Compiled from United Network for Organ Sharing web site, 1996.
SOURCE: Compiled from United Network for Organ Sharing web site, 1996; and Company estimates, compiled
from IPO Prospectus, 1990.
Mortality
Awaiting
Transplant
35%
25%
35%
N/A
estimates, compiled
Exhibit 6 Potentital Demand Estimates by Indication and Donor Type, U.S. 1990
110,000
Exhibit 14 BioTransplant Inc. Selected Consolidated Financial Data
Revenues:
License fees $ - $ - $ 1,500 $ 1,500
Research and development - - 1,125 1,500
Interest income 14 114 66 163
Total revenues 14 114 2,691 3,163
Expenses:
Research and development 1,821 4,985 8,218 11,767
General and administrative 776 1,235 1,680 2,518
Interest 54 82 542 146
Total expenses 2,651 6,302 10,440 14,431
Net income (loss) $ (2,637) $ (6,188) $ (7,749) $(11,268)
$ 4,000 $ 7,000
5,875 8,500
168 525
10,043 16,025
9,461 36,275
1,939 8,266
731 1,566
12,131 46,907
$ (2,087) $ (30,072)
$ 2,343 $ 2,489
148 86
4,801 5,372
1,066 615
23,772 29,241
(27,030) (28,840)
Exhibit 15 BioTransplant Inc. Estimated Profit and Loss Statement as of 1996
SOURCE: UBS Securities and BioTransplant, compiled from IPO prospectus, 1996.
Exhibit 16 Alexion Pharmaceuticals Inc. Selected Consolidated Financial Data, 1995
Sales $ - $ 0.1
Total revenues - 0.1
Total expenses - 7.2
Net income (loss) - (7.1)
Expenses:
Cost of goods sold 0.6 0.2 13.6 16.7 17.9
Depreciation, depletion, and amortization 0.4 0.8 1.5 1.6 1.4
Interest 0.1 0.2 0.4 0.4 0.7
General and administrative 5.9 10.1 - - -
Total expenses 7.1 11.4 13.8 18.8 22.4
Net income (loss) (6.4) (10.0) (12.5) (16.5) (8.9)
Revenues:
Expenses:
Expenses: