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a.
b.
c.
d. Alpha1 Receptors
i. Eyes: mydriasis (dilation)
ii. Blood vessels: vasoconstriction
iii. Male sex organs: ejaculation
iv. Bladder: contraction
e. Alpha 2 receptors
i. Location: presynaptic nerve terminals
ii. Regulates transmitter release by suppressing further release of norepinephrine or epinephrine.
iii. Helps reduce transmitter release when too much transmitter has accumulated in the synaptic
gap.
f. Beta 1 receptors
i. Heart: increase rate, increased force of contraction, increased AV conduction velocity
ii. Kidney: release of renin to increase blood pressure.
g. Beta 2 receptors
i. Lungs: bronchial dilation
ii. Uterus: relaxation
iii. Heart, lungs, skeletal muscle: vasodilation (opposite of alpha 1 activation)
iv. Liver and skeletal muscle: glycogenolysis, increases blood glucose
4. Identify and compare the actions of four categories of drugs that affect the ANS; (sympathomimetic/adrenergic,
sympatholytic, parasympathomimetic/cholinergics & parasympatholytics)
a. Sympathomimetic/adrenergic agonists
i. Direct receptor binding: bind to adrenergic receptors and mimick the actions of natural
transmitters
ii. Promotion of NE release: indirect activation of adrenergic receptors
iii. Inhibition of NE reuptake
iv. Inhibition of NE inactivation
b. Adrenergic antagonists
i. Reversible direct blockade of adrenergic receptors.
ii. Selective
5. Describe the side effects/adverse reactions of cholinergic, cholinergic blocking, and synthetic antispasmodic
agents.
6. Discuss the nursing management for the care of clients receiving agents affecting the parasympathetic nervous
system and for those receiving adrenergic, and adrenergic-blocking drugs.
7. List common adrenergic drugs and blocking agents, their effects, and side effects/adverse reactions.
8. Obtain/prepare drug references on each of the following drugs: epinephrine, NE, propranolol, prazosin,
acetylcholine, atropine, bethanechol, donepezil
Objectives: After studying this topic the student should be able to:
4. Describe several side effects and adverse reactions related to thiazide, loop, and potassium-sparing diuretics.
a. Loop diuretics
i. Hyponatremia, hypochloremia, and dehydration
1. Use of furosemide can produce excessive loss of sodium, chloride, and water. Severe
dehydration can result. Dehydration can promote hypotension, thrombosis, and
embolism
ii. Hypotension
1. Loss of volume and relaxation of venous smooth muscle
iii. Hypokalemia
iv. Ototoxicity
5. Explain the nursing interventions, including client teaching, related to diuretics, especially thiazide, loop, and
potassium -sparing diuretics.
6. Identify the categories of antihypertensive drugs, and the stepped-care approach and the modified
pharmacologic approach to antihypertensive drugs.
8. Describe the side effects and adverse reactions to sympatholytics (beta blockers, centrally acting ad peripherally
acting alpha blockers, alpha and beta blockers), direct-acting vasodilators, and angiotensin antagonists.
10. Explain the major nursing diagnoses and goals in caring for hypertensive patients.
Prepare Drug Reference Information for the following drugs.
losartan nifedipine
aliskiren
Class Topic: Acute Coronary Syndrome (ACS), Antiaginal and Heart Failure Medications
Objectives: After studying this topic the student should be able to:
4. Identify the side effects and adverse reactions of nitrates, beta blockers, calcium channel blockers, ACE
inhibitors, and ARB.
5. Explain the nursing process, including client teaching related to ACS, antianginal and heart failure drugs.
Prepare Drug Reference Information for the following drugs. Drug information is to include :
Objectives: After studying this topic the student should be able to:
2. Apply the nursing process, including client teaching, for the patient receiving anticoagulant therapy
Prepare Drug Reference Information for the following drugs. Drug information to include
heparin
warfarin
enoxaparin
tPA
clopidogrel
aspirin
dabigatran
rivaroxaban
Class 2/21/17
Clopidogrel
Herapin
WHY; quick onset
Enoxaparin
No labs to monitor
Indication: prevention of DVT, pro pharylxic
T-pa
Indication: clogged central line
Arterial clot most common