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ACN 6340/HCS 6340 CELLULAR
work with models describing electrical activity of
NEUROSCIENCE — Spring 2011 neurons, particularly the role of ion channels in
maintaining and altering neuronal membrane
Monday & Wednesday 02:30 PM ‐ 03:45:PM polarization,
CB3 1.304
describe mechanisms of synaptic transmission and
synaptic plasticity induced by experience,
Instructor Contact Information describe and analyze neurophysiological recording
Dr. Sven Kroener methods used to assess neuronal activity, and limits
GR 4.204 of these techniques.
Phone: 972‐883‐5671
kroener@utdallas.edu Required Textbook and Materials:
Office hours: Monday and Wednesday after class, D. Purves et al., (eds) Neuroscience 4th edition
or by appointment. (2007) ISBN‐10: 0878936971, and
E.R. Kandel, J.H. Schwartz, and T.M. Jessell (eds)
Principles of Neural Science (2000) ISBN‐10:
Prerequisites: None 0071120009
Course Description:
Exams and Assignments:
Purpose of the course is to supply the basic notions in
Exams: Students will be evaluated with 2 tests during
the field of cellular neuroscience, and the intellectual
the semester, an oral presentation, and the final exam.
tools for understanding recent advances of the
Tests will consist of multiple choice questions covering
molecular and cellular events underlying neural
the preceding lessons.
signaling, synaptic transmission and plasticity. To this
Each Test will count 40 points toward the final grade.
end the basic morphology and functions of neurons and
The oral presentation counts 60 points, and the Final
glia, describing cytology of subcellular organelles in
Exam counts 100 points for a total of 240 points (see
neuronal cells, familiarizing the students with electric
below).
neuronal models, and illustrating as examples the
neuromuscular junction, central synapses, synaptic
Grading Policy
integration and plasticity
Grading is based on a set of a priori criteria: 90% (or
Student Learning Objectives: 215+ points) correct for A, ~80% (or 190+ points) for B,
After completing the course, students should be able to: ~70% (or 165+ points) for C, and ~60% (or 140+ points)
for D, less than ~60% (140 points) is automatically an F.
Course Learning Objectives The instructor reserves the right to change the
After completing the course, students should be able to: evaluation criteria (grade brackets) at his discretion,
Describe and analyze the contributions of even from test to test. No extra test will be available for
anatomical, physiological, behavioral, any reason.
pharmacological, developmental, and cell and
molecular biological studies to the bases of Attendance: Attendance of classes is not mandatory
neuroscience, but is strongly recommended, as tests will be based on
describe the basic morphology and functions of material taken from the classes and will not be
neurons and glia, restricted to the topics and textbooks indicated in this
use proper scientific terminology for syllabus, which serves predominantly as a guideline to
neurotransmitters, neurotransmitter receptors, and the course.
neurotransmitter receptor/effector signaling
systems,
describe cytology of subcellular organelles in
Schedule:
Class # DATE TOPIC ASSIGNMENTS
1 Mon Jan. 10 Introduction Purves Ch. 1; Kandel Ch. 1
2 Wed Jan. 12 Structure of neurons Kandel Ch. 4,5; class materials
Mon Jan 17 NO CLASS – Martin Luther King Day
3 Wed Jan 19 Glia and Neurons Purves Ch. 1; Kandel Ch. 2
4 Mon Jan 24 Membrane Potential Purves Ch. 2
5 Wed Jan 26 Action potential Purves Ch. 3
6 Mon Jan 31 Passive membrane properties Purves Ch. 3
7 Wed Feb 2 Activity in neuronal networks Kandel Ch. 2; class materials
8 Mon Feb 7 Review
9 Wed Feb 9 Test 1
10 Mon Feb 14 Ion channels and transporters Purves Ch. 4; Kandel Ch. 6
11 Wed Feb 16 The neuromuscular junction Purves Ch. 5; Kandel Ch. 11
12 Mon Feb 21 Synaptic transmission Purves Ch. 5; Kandel Ch. 10‐14
13 Wed Feb 23 Synaptic transmission Purves Ch. 5; Kandel Ch.10‐14
14 Mon Feb 28 Neurotransmitters and their receptors Purves Ch. 6; Kandel Ch. 15
15 Wed Mar 2 Neurotransmitters and their receptors (continued) Purves Ch. 6; Kandel Ch. 15, 16
16 Mon Mar 7 Neurotransmitters and their receptors (continued) Purves Ch. 6; Kandel Ch. 15
17 Wed Mar 9 Review
Mon Mar 14 SPRING BREAK – NO CLASS
Wed Mar 16 SPRING BREAK – NO CLASS
18 Mon Mar 21 Test 2
19 Wed Mar 23 synaptic plasticity (LTP – LTD) Purves Ch. 8; Kandel Ch. 63
20 Mon Mar 28 Spike timing‐dependent plasticity Purves Ch. 8
21 Wed Mar 30 Molecular Signaling within Neurons Purves Ch. 7; Kandel Ch. 13
22 Mon Apr 4 Molecular Signaling within Neurons Purves Ch. 7; Kandel Ch. 13
23 Wed Apr 6 Student presentation TBA
24 Mon Apr 11 Student presentation TBA
25 Wed Apr 13 Student presentation TBA
26 Mon Apr 18 Student presentation TBA
Wed Apr 20 NO CLASS
27 Mon Apr 25 Student presentation TBA
28 Wed Apr 27 Student presentation TBA
29 Mon May 2 Review TBA
32 Wed May 11 FINAL Exam
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This course will use the resources of turnitin.com, which searches the web for disabilities educational opportunities equal to those of their non‐disabled
possible plagiarism and is over 90% effective. peers.
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