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‫هذه السئله إهداء من عبدال الحضري‬

abd-yus@hotmail.com

Pharmacology I

Choose the correct answer

:The chemical name of the drug is-1


A. The first name given to any drug
B. The name suggested by the first manufacturer
C. The name is chosen by the marketing department of
the drug company
D. It is often short , catchy and easy to remember

:The Generic name of the drug-2


A. It is often a shortened form of the chemical name
B. The name chosen by the marketing department of the
drug company the drug company
C. The name suggested by the first manufacturer
D. Both a and c

A drug may produce its effects through the following -3


:mechanisms except
A. Physical action
B. Chemical action
C. Elimination
D. Regulatory proteins

:Physical action of a drug means the following except -4


A. Osmosis
B. Adsorption
C. Antacids
D. Osmosis and Adsorption

:Chemical action of the drug can be like the effects of -5


A. Adsorption
B. Osmosis
C. Antacids
D. Adsorption and Osmosis

:Which of the following is an Enzyme inhibitor -6


A. Cimetidine
B. Phenobarbitone
C. Cimetidine and Phenobarbitone
D. Phenytoin

:Which of the following is an Enzyme inducer -7


A. Estrogen
B. Phenytoin
C. Progesterone
D. None of the above

:Reversible antagonist makes – 8


A. Weak bond with the receptor
B. Strong bond with the receptor
C. Do not react with the receptor
D. None of the above

Irreversible antagonist makes -9


A. Weak bond with the receptor
B. Strong bond with the receptor
C. Do not react with the receptor
D. None of the above

Heparin solutions form chemical complexes with the -10


:following except
A. Chlorpromazine
B. Gentamycin
C. Famotidine
D. Streptomycin

:Dextran solutions form chemical complexes with-11


A. Tetracycline
B. Hydrocortisone
C. Tetracycline and Hydrocortisone
D. None of the above

Synergism means -12


A. ( 1+1 = > 2)
B. ( 1 + 1= 2 )
C. ( 0 +1 = > 1)
D. None of the above

:a.c abbreviation means -13


A. After meals
B. Before meals
C. At bedtime
D. Must be cracked

IM abbreviation means -14


A. Intramuscularly
B. Intravenously
C. Subcutaneously
D. Immediately

:The abbreviation of Twice a day is -15


A. t.i.d
B. q.i.d
C. b.i.d
D. OD

An alcoholic solution of volatile substances -16


A. Elixir
B. Lotion
C. Liniment
D. Spirit

Elixir a solution containing -17


A. Alcohol
B. Sugar
C. Flavoring substance
D. All of the above

:Which of the following is an Inhalation anesthetic– 18


A. Thiopental
B. Halothane
C. Ketamine
D. Propofol

:Which of the following is an Intravenous anesthetic -19


A. Nitrous oxide
B. Enflurane
C. Thiopental
D. Halothane

All sedatives become hypnotics in– 20


A. Large doses
B. Low doses
C. The same doses
D. Minimum doses
:The aim of antiparkinsonian drugs is to -21
A. Decrease dopamine in the basal ganglia
B. Increase dopamine in the basal ganglia
C. No effect on dopamine in the basal ganglia
D. None of the above

:Which of the following is a Typical antipsychotic drug -22


A. Risperidone
B. Chlorpromazine
C. Clozapine
D. Risperidone and Chlorpromazine

Potentiation means -23


A. ( 0 + 1 = > 1)
B. ( 1 + 1 = 2 )
C. ( 1 + 1 = > 2)
D. None of the above

:The mechanism of action of antidepressants is to -24


A. Decrease norepinephrine and /or serotonin in the CNS
B. Increase norepinephrine and /or serotonin in the CNS
C. Increase dopamine in the CNS
D. Have no effect on norepinephrine neither serotonin in
the CNS

Which of the following is an Antimania drug (Mood -25


:(stabilizing drugs
A. Lithium
B. Morphine
C. Phenelzine
D. Norepinephrine

:All of the following are catecholamines except -26


A. Epinephrine
B. Dopamine
C. Ephedrine
D. Dobutamine

:Which of the following is a Selective α1-blocker-27


A. Prazosin
B. Sotalol
C. Propranolol
D. All the above

:Bromocriptine is used for -28


A. Suppression of lactation
B. Treatment of parkinsonism
C. Treatment of parkinsonism and Induction of lactation
D. Treatment of parkinsonism and Suppression of
lactation

Organophosphorous compounds are -29


A. Reversible Choline estrase inhibitors
B. Irreversible Choline estrase inhibitors
C. No effect on Choline estrase
D. Reversible Choline esterase inducers

Antidote for organophosphorous toxicity-30


A. Atropine with oximes
B. Physostigmine
C. Neostigmine
D. Scopolamine and Neostigmine

:Which of the following drugs is used as antispasmodic -31


A. Cyclopentolate
B. Ipratropium
C. Biperidin
D. Hyoscine butylbromide
Which of the following is an Antidote for atropine -32
:toxicity
A. Physostigmine
B. Benztropine
C. Dicyclomine
D. Hyoscine

Salbutamol and Terbutaline are -33


A. Antihypertensives
B. Bronchodilators
C. Hypoglycemics
D. Sedatives

:Therapeutic uses of Pilocarpine is -34


A. Glaucoma
B. Antispasmodic
C. Antihypertensive
D. All of the above

Therapeutic uses of Ergotamine -35


A. Acute attacks of migraine
B. All states of migraine
C. Chronic attacks of migraine
D. Prevention of attacks of migraine

Which of the following is an Atropine substitute used as -36


:antiparkinsonian
A. Ipratropium
B. Cyclopentolate
C. Benztropine
D. Nizatidine
Which of the following is an Atropine substitute used as -37
:mydraitic
A. Benztropine
B. Ipratropium
C. Dicyclomine
D. Cyclopentolate

Which of the following is an Atropine substitute is used -38


:as bronchodilator
A. Ipratropium
B. Hyoscine butylbromide
C. Biperidin
D. Pirenzepine

Which of the following Atropine substitutes is used to -39


:decrease acid secretion in peptic ulcer
A. Dicyclomine
B. Benztropine
C. Homatropine
D. Pirenzepine

Which of the following is a Non-depolarizing agent such -40


:as
A. Pancuronium
B. Succinylcholine
C. Pancuronium and Succinylcholine
D. None of the above

:Which of the following is a Depolarizing agent-41


A. Atracurium
B. Decamethonium
C. Pancuronium
D. Hexamethonium

Which of the following is a Centrally acting skeletal -42


:muscle relaxant
A. Orphenadrine citrate
B. Atracurium
C. Pancuronium
D. None of the above

:Which of the following is a Loop diuretic -43


A. Furosemide
B. Indepamide
C. Acetazolamide
D. Dorzolamide

:The site of action of Thiazides is in-44


A. Ascending limb of loop of Henle
B. Proximal convoluted tubule
C. Early distal convoluted tubule
D. Entire tubule

:Which of the following is a Thiazide diuretic-45


A. Furosemide
B. Indepamide
C. Acetazolamide
D. Dorzolamide

:Which of the following is a K- sparing diuretic -46


A. Spironolactone
B. Mannitol
C. Spironolactone and Mannitol
D. Spironolactone and Glycerin

:Main adverse effects of K-sparing diuretics is -47


A. Hyponatraemia
B. Hyperkalemia
C. Hypokalemia
D. Metabolic acidosis

:Which of the following is an Osmotic diuretic-48


A. Bumetanide
B. Amiloride
C. Ethacrynic acid
D. Mannitol

Which of the following is a Carbonic anhydrase-49


:inhibitor
A. Acetazolamide
B. Mannitol
C. Ethacrynic acid
D. Indepamide

:Thiazide diuretics are used in-50


A. Severe and resistant hypertension
B. Mild to moderate hypertension
C. Glaucoma
D. Hyperglycemia

It is a condition in which cardiac output is less than the-51


:body needs
A. Arrhythmia
B. Angina
C. Congestive heart failure
D. Bradychardia

An acute chest pain that occurs when coronary blood-52


flow is inadequate to supply the oxygen required by the
:heart
A. Arrhythmia
B. Angina
C. Congestive heart failure
D. Bradychardia

:Arrhythmia is -53
A. Any abnormal heartbeat
B. Disorders of impulse formation
C. Disorders of impulse conduction
D. All of the above

:Gemfibrozil is-54
A. Antihyperlipidemia
B. Antiangina
C. Antiarrhythmia
D. Antihypertensive

:Propranolol is used in the following indications except-55


A. Antihypertensive
B. Antiarrhythmia
C. Anti-spasmodic
D. Prophylaxis of migraine

:Which of the following is a Long-acting nitrate-56


A. Isosorbide mononitrate
B. Amyl nitrite
C. Isosorbide mononitrate and Amyl nitrite
D. None of the above

57-Which of the following is an Angiotensin-1 receptor


antagonist:
A. Captopril
B. Candesartan
C. Captopril and Enalapril
D. Enalapril

:Which of the following is Direct-acting vasodilator-58


A. Minoxidil
B. Hydralazine
C. Diazoxide
D. All of the above

Which of the following is not a H2-receptor -57


: antagonist
A. Cimetidine
B. Histidine
C. Ranitidine
D. Famotidine

Which of the following is a Proton pump (H/K ATPase)-58


:inhibitor
A. Omeprazole
B. Cimetidine
C. Sucralfate
D. Propranolol

Absorbable antacid such as -63


a) NaHCO3
b)CaCO3
c)Mg(OH)2
d)Both a and b

:Which of the followings are side effects of Al(OH)3 -60


A. Constipation
B. Diarrhea
C. Diarrhea and Hyperphosphatemia
D. Constipation and Hypophosphatemia
Which of the following are drugs that induce reflex-61
:vomiting
A. Emetics
B. H2-receptor antagonist
C. Anti-vomiting
D. Anti-emetics

Drugs that cause mild purgation -66


a)Cathartics
b)Prokinetics
c)Antispasmodics
d)Non of the above

Loperamide is the opioid antidiarrheal of first choice -67


because
a)Central nervous system effects
b)Has no Central nervous system effects
c)It is natural drug
d)Non of the above

Oral Rehydration Solution(ORS) contains -68


a)NaOH
b)NaHCO3
c)Both a and b
d)Non of the above

:Which of the following is a Smooth Muscle relaxant -69


A. Papaverine
B. Hyoscine butyl bromide
C. Atropine
D. Dexamethasone
Which of the following are the drugs used to alleviate-70
:meteorism
A. Antacids
B. Antiemetic
C. Antidiarrhoeals
D. Antiflatulents

.Is a sudden,continuous and intense asthmatic attack -71


a) Acute sever asthma
b) Chronic asthma
c) Bronchial asthma
d) All of the above

Xanthines such as-72


a) Aminophylline
b) salbutamol
c) Terbutaline
d) All of the above

Synthetic xanthine such as-73


a) Aminophylline
b) Theobromine
c) Theophylline
d) Caffeine

Mast cell stabilizers such as-74


a) Aminophylline
b) Ketotifen
c) Salbutamol
d) Non of the above

Leukotriene inhibitors such as-75


a) Zileuton
b) Zafirlukast
c) Montelukast
d) All of the above

Productive cough-76
a) Useful cough
b) Associated with sputum
c) Treated by expectorants
d) All of the above

Nonproductive cough-77
a) Useful cough
b) Associated with sputum
c) Treated by expectorants
d) Non of the above

Central non-narcotic antitussives-78


a) Dextromethorphan
b) Codeine
c) Guaifenesin
d) Ketotifen

Central narcotic antitussives-79


a) Dextromethorphan
b) Codeine
c) Guaifenesin
d) Ketotifen

Mucolytics such as-80


a) Bromhexine
b) Ambroxol
c) Acetylcyctine
d) All of the above

Sulphonyl ureas first generation e.g-81


a)Glipizide
b)Tolbutamide
c)Metformin
d)Pioglitazone

Estrogen antagonist e.g-82


a)Clomiphene
b)Mifepristone
c)Both a and b
d)Non of the above

Immunosuppressive drugs such as-83


a)Cyclosporine
b)Azathioprine
c)Both a and b
d)Non of the above

Immunostimulant drugs such as-84


a)Cyclosporine
b)Azathioprine
c)Levamisole
d)Non of the above

Quinolones are-85
a)Inhibit DNA synthesis
b)Bacteriostatic agents
c)Both a and b
d)Non of the above

Sulphonamides are-86
a)Inhibit DNA synthesis
b)Inhibit bacterial folic acid pathway
c)Bactericidal
d)Non of the above

Pencillins are-87
a)Inhibit DNA synthesis
b)Inhibit bacterial folic acid pathway
c)Inhibit bacterial cell wall synthesis
d)Bacteriostatic

88-2nd generation cephalosporins such as


a)Cephadroxil
b)Cefoperazone
c)Cefepime
d)Cefaclor

:Which of the following antibiotics is a Macrolide -89


A. Streptomycin
B. Doxycycline
C. Azithromycin
D. Pyrazinamide

Which of the following statements is correct about -90


:Isonizid
A. It is designed as INH
B. It decreases cell wall synthesis
st
C. It is used as 1 line drug in treatment of tuberculosis
D. All of the above

The killing of all microorganisms, whether-91


:pathogenic, dormant, or nonpathogenic refers to
A. Disinfection
B. Sterilization
C. Antisepsis
D. Contamination

Antifungal agents such as-92


a)Ketoconazole
b)Nystatin
c)Grisofulvin
d)All of the above
:Which of the following is an Anti-herpes virus agent -93
A. Acyclovir
B. Nystatin
C. Both A and B
D. None of the above

Amantadine is-94
A. Prophylaxis for influenza A
B. Inhibits synthesis of guanine nucleotides
C. Both a and b
D. None of the above

:Acetylsalicylic acid is used as-95


A. Antipyretic
B. Analgesic
C. Anti-platelet in low dose
D. All of the above

:Which of the following is a Selective COX-2 inhibitor-96


A. Indomethacin
B. Celecoxib
C. Paracetamol
D. Tolmetin

:Allopurinol is used in-97


A. a)Treatment of gout
B. b)Treatment of cancer
C. c)Treatment of vomiting
D. d)Treatment of leprosy

:Cyclophosphamide is used in-98


A. Treatment of gout
B. Treatment of cancer
C. Treatment of vomiting
D. Treatment of leprosy

:Paclitaxel may be used-99


A. Ovarian and breast carcinomas
B. As antiplatelet
C. Septicemia
D. Anaphylactic shock

Which of the following statements is correct about Non--100


:selective COX inhibitors
A. Inhibit both COX-1 and COX-2
B. Such as sulindac
C. May induce gastric ulcer
D. All of the above

‫هذه السئله إهداء من عبدال الحضري‬


abd-yus@hotmail.com