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Amino acids are the building blocks of proteins in the body and are singly
responsible for 75% of the dry body weight (i.e. sans water). They are
needed for the production of proteins, hormones, neurotransmitters, neuclei
acids and peptides. These are the structural components of the every tissue,
organ and cell in the body. Amino acids are likewise needed for normal
biochemical processes and overall functioning, differentiation and
organization of cells, tissues and organ-systems.
Amino acids can exist in either the D or L forms. These forms are purely the
same molecules but in opposite optical orientations. The L form is the form in
which the human body utilizes amino acids except for phenyalanine which
can be used in both forms. This is important since the inclusion of D forms
amino acids in supplement formations is mostly perfunctory and not
important.
Only three amino acids are classified as branched chain amino acids (BCAA).
These are leucine, isoleucine and valine. The importance of branched chain
amino acids stems from their usefulness in enhancing the immune system
and improving stamina and endurance. These make them right for
bodybuilders and athletes as well as in the treatment of certain diseases.
The primary function of most of the amino acids is the production of proteins.
Each amino acid is linked to two others in short linear chains of peptides.
Longer peptides are called polypeptides or proteins when fully folded. The
entire process is mediated by mRNA (messenger ribonucleic acid) which
itself is built of amino acids. Apart from protein production, amino acids can
also precursors of other molecules such as neurotransmitters, heme in the
hemoglobin of the red blood cell, polyamines, nucleotides and nitric oxide.
The food sources of amino acids include fruits and vegetables, grain, meat
and dairy products. However, supplements may be required to augment
uptake of amino acids from restricted diets or in those with digestive
problems. Those for which amino acids supplementation is an absolute
necessity include vegetarians, people with chronic diseases, those with
allergies, people on poor diets and everyone undergoing stress. The need for
amino acids supplementation can range from clear signs such as wasting
and specific metabolic dysfunctions to vague indicators such as malaise,
weakness and exacerbation of stress.
Certain amino acids can offer specific benefits. For example:
Some amino acids are also useful for athletes to gain lean muscles, promote
endurance and hasten healing (glutamine and BCAAs); they can also help
with weight loss and are used in children to treat ADHD. However, generally,
amino acids help develop and maintain the muscular, digestive,
cardiovascular, neurological and immune systems.