Escolar Documentos
Profissional Documentos
Cultura Documentos
Faculty of
Science and
Pharmacy
Technology
Course Information
Course Title Medicinal Chemistry I
Course Number Phar 321
Course Credits 3
Course Time Mon Wed: Sec 1, 11.15 -12.45
Prerequisites Pharmaceutical Organic Chemistry II, (Phar 222)
Instructor Dr. Qosay Al-Balas
Office Location P2 Level -2
Office Phone Dr. Al-Balas: 72010 00 Ext. 23416
Office Hours Mon-Wed: 9:45-11:15
E-mail qabalas@just.edu.jo
Text Book
Title Introduction to Medicinal Chemistry
Author(s) Graham Patrick
Publisher
Year 2009
Edition 4th
References Foye's Principles of Medicinal Chemistry, David A Williams, William
O Foye and Thomas L Lemke, 6th Edition, 2008, Lippincott Williams &
Wilkins
Assessment Policy
Assessment Type Expected Due Date Weight
First Exam TBA 30%
Second Exam TBA 30%
Final Exam TBA 40%
Intended Learning Outcomes (ILOs)
After completing this course successfully, the student is expected to:
Course Content
Week Chapter in
Topics
Text
1 1. Introduction to Medicinal Chemistry.
1.1 What is Medicinal Chemistry? Introduction
1.2 Classification of Drugs
2-4 2. Drug Absorption and Distribution
2.1 Gastrointestinal Tract and Biomembranes
2.2 Mechanisms of Drug Absorption 7
2.3 Physicochemical Properties of Drugs
2.4 Drug Distribution
5-8 3. Structural Medicinal Chemistry
3.1 Definitions
3.2 Receptors
3.3 Drug-Receptor Interaction
4,5
3.4 Factors Affecting Drug-Receptor Interaction
3.5 Bioisosterism
3.6 From Functional Groups to Molecular Chemistry
3.7 Molecular Mechanism of Drug Action
9-12 4. Drug Metabolism and Excretion
4.1 Introduction
8
4.2 Structure-Metabolism Relationships (SMR)
4.3 Metabolic Reactions
4.4 Factors Affecting Metabolism.
4.5 Drug Excretion
13,14 5. Drug Development 2
Additional Notes
Exams • The format for the exams is generally (but NOT always) as
follows: Multiple-choice and short essay questions.
• Grades will not be given out via e-mail
Makeup Exams • Makeup exam should not be given unless there is a valid
excuse.
• Arrangements to take an exam at a time different than the one
scheduled MUST be made prior to the scheduled exam time.
Drop Date • Last day to drop the course is before the twelve (12 th) week of
the current semester.
Cheating The commitment of the acts of cheating and deceit such as copying
during examinations, altering examinations for re-grade, plagiarism of
homework assignments, and in any way representing the work of others
as your own is dishonest and will not be tolerated. Standard JUST policy
will be applied
ضبط الطالب أثناء المتحان أو الختبار متلبسا ً بالغش فتوقع عليهُ إذا:7 المادة
:العقوبات التالية مجتمعة
. اعتباره راسبا ً في ذلك المتحان أو الختبار-أ
. الغاء تسجيله في بقية المساقات المسجل لها في ذلك الفصل-ب
و هو الفصل التالي للفصل، فصله من الجامعة لمدة فصل دراسي واحد-جـ
.الذي ضبط فيه
Attendance • Excellent attendance is expected.
• JUST policy requires the faculty member to assign ZERO
grade (35) if a student misses 10% of the classes that are not
excused.
• If you miss class, it is your responsibility to find out about any
announcements or assignments you may have missed.
Workload • Average work-load student should expect to spend is 6
hours/week
Graded Exams • Instructor should return exam papers graded to students not
after the week after the exam date.