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Masalehdan et al. Vol. 18, No. 5/August 2010/J. Opt. Soc. Am.

5245
BIOMED/DH

Modeling of Zernike Optical Aberrations by MTF and


PSF
Hossein Masalehdan1,2 *, Afshin Lotfi3, Erik S. Lotfi4,5, Kazem Jamshidi-Ghaleh6
1
Optics and Laser Engineering Department, (Young Research Club), Islamic Azad University, Bonab
Branch, 55518-134 Bonab, Iran
2
Department of Applied Physics, Smithsonian Institute, Washington, D.C. 20013-7012, USA.
3
Department of Ophthalmology,School of Medicine,Alavi Hospital,University of Medical Sciences,Tabriz,Iran.
4
Faculty of Bonab Engineering and Technology, Bonab, Iran.
5
Quantum Chemistary Laboratory, Chemistry Department, Rice University, 6100 Main street,
Houston, TX 77005, USA
6
Optics Engineering Group, Physics Dep. Azerbaijan University of Tarbiyat Moallem, Tabriz, Iran.
*Corresponding author: h.masalehdan@gmail.com

Received December 21, 2009; revised February 11, 2010; accept April 13, 2010;
posted June 17, 2010 (Doc. ID 101370); Published August 11, 2010
Currently there is considerable interest in correcting the higher-order optical aberrations of the human
eye. Present-day laser eye surgery techniques like PRK and LASIK correct only defocus and
astigmatism, which are 2nd order aberrations. Surgically correcting the additional higher-order
aberrations could extend the limits of human vision beyond 20/20. In addition, this type of capability
could be used to eliminate the higher-order aberrations that may have been caused by a prior surgical
procedure. These induced aberrations are responsible for the glare, halos, and other visual defects that
have been reported by some eye surgery patients. © 2010 Optical Society of America
OCIS codes: 170.0170, 320.0320, 170.5755, 320.2250

optics, if you know the wave aberration function, you


1. INTRODUCTION know what must be done to the light entering the pupil
The main application involves the high-resolution to create an image [4] on the retina that is limited only
imaging of the retina and other structures (rods, cones, by diffraction and scattering.
nerve fibers, blood vessels, capillaries, pigment cells, Understanding what is needed to correct defocus
etc.,) using adaptive optics [1] for the diagnosis and and astigmatism can be accomplished by having
treatment of eye disorders . patients view targets through sets of sphero-cylinder
To determine and apply the proper correction that test lenses [5,6]. However, determining the other
will eliminate or minimize these aberrations, their higher order wave aberrations requires more
characteristics must first be captured and sophisticated techniques. Wavefront measuring
quantitatively described. The wave aberration instruments like the Shack-Hartmann Sensor are being
function suits this purpose well because it completely utilized to provide data from which the wave
describes the aggregate effects of the cornea and lens aberrations of the human eye can be accurately and
on light passing through every location in the pupil. It reliably estimated.
defines how the phase of the light is affected after it For the above reasons a mathematical formulation
has propagated through the optical system. In the case is needed, not only to quantitatively describe the
of laser eye surgery, if you know the wave aberration aberrations, but also to facilitate accurate estimation of
function [7-9], you know what must be done to the the wave aberration function from measurement data.
refractive properties of the eye to create an image on In response to the perceived need in the vision
the retina that is limited only by diffraction and community, the Optical Society of America formed a
scattering [9]. For retinal imaging with adaptive

1096-7637/10/10137-5/$15.00 © 2010 Optical Society of America


5246 J. Opt. Soc. Am. /Vol. 18, No. 5/August 2010 Masalehdan et al.

task force and charged it with the mission of For visual applications it is often more convenient
developing recommendations on definitions, to express the PSF and MTF in terms of visual angle.
conventions, and standards for the reporting of optical These expressions are given by :
aberrations of human eyes. One major outcome has 𝜆2
been a recommendation adopting the use of Zernike 𝑃𝑆𝐹 (𝑠𝑖𝑛�𝜃𝑥 ), 𝑆𝑖𝑛(𝜃𝑦 � = �𝐹𝑇 �𝑃(𝑥/𝜆. 𝑦/
𝐴𝑝
Polynomials for this purpose [5]. The objectives of 𝜆. 𝑒−𝑖 2𝜋𝜆𝜔𝑥/𝜆,𝑦/𝜆2 (4)
this course project include an explanation of why
Zernike polynomials are preferred over other 𝑃𝑆𝐹 �𝜃𝑥 ), (𝜃𝑦 � ≅
functions, a mathematical definition of Zernike 𝜆2𝐴𝑝 𝐹𝑇𝑃𝑥/𝜆.𝑦/𝜆. 𝑒−𝑖 2𝜋𝜆𝜔𝑥/𝜆,𝑦/𝜆2 (5)
polynomials, their use in describing the wave
aberration function, a simulation showing the effects
of the higher order aberrations on image quality, and (The eq.5 use for small angles.)
an illustration of how Zernike polynomials are used to 𝐹𝑇 {𝑃𝑆𝐹�𝜃𝑥 ),(𝜃𝑦�}
𝑂𝑇𝐹�𝑆𝑥 , 𝑆𝑦 � = (6)
estimate the wave aberration function from 𝐹𝑇 {𝑃𝑆𝐹�𝜃𝑥 ),(𝜃𝑦�} |𝑆𝑥 = 𝑆𝑦 =0
measurement data. 𝑀𝑇𝐹�𝑆𝑥 , 𝑆𝑦 � = �𝑂𝑇𝐹 �𝑆𝑥 , 𝑆𝑦 � � (7)
2. THE EFFECTS OF ALL ORDERS ABERRATIONS
ON IMAGE GENERATING QUALITY
The calculations and computational domains are
Aberrations negatively impact image quality. They illustrated in Figures 1 and 2.
change the size and shape of impulse response or point
spread function (PSF), which blurs the image. In
terms of frequency analysis, the frequency response of
the optical system is reduced by phase distortion
within the passband.
The effects of aberrations can therefore be
characterized by calculating the PSF or MTF
(Modulation Transfer Function) of the optical system
[5].
3. THE PHYSICAL MODELING OF EYE OPTICAL
ABERATIONS
Abbreviations and acronyms the first time they are
used The image of a point object formed by the optical
system is the point spread function or impulse
response [5,6].It is defined as:
𝑃𝑆𝐹(x. y) =

1 −i ω(x,y)
�𝐹𝑇 �𝑃(x. y). e λ � 𝑓𝑥= 𝑥 , 𝑓𝑥= 𝑦 � 2 (1)
A2 d2 AP 𝜆𝑑 𝜆𝑑

The Modulation Transfer Function is modulus of


the Optical Transfer Function. The OTF and MTF are Fig.1. PSF calculation and Computational Domains.
given by :
FT {PSF}
OTF�Sx , Sy � =
FT {PSF}Sx = Sy = 0

−i ω(x,y)
FT �FT �P(x. y). e λ � fx= x , fx= y � 2
λd λd
= 2π (2)
−i ω(x,y)
FT �FT �P(x. y). e λ � fx= x , fx= y � 2 Sx = Sy = 0
λd λd

𝑀𝑇𝐹�𝑆𝑥 , 𝑆𝑦 � = �𝑂𝑇𝐹 �𝑆𝑥 , 𝑆𝑦 � � (3)


The OTF can also be calculated as the auto-
correlation of the generalized pupil function, but
because the FFT will be used for computational
efficiency, the OTF will be calculated using the
Fourier transform of the PSF.
Masalehdan et al. Vol. 18, No. 5/August 2010/J. Opt. Soc. Am. 5247

by ZernikePolynomial.m, up to 6th order in a pyramid


arrangement.

Two Matlab scripts, ZernikePolynomialPSF.m and


ZernikePolynomialMTF.m utilize equations 4-7 to
generate and plot the PSF and MTF for any wave
aberration mode associated with any Zernike
polynomial specified by n, m, pupil diameter (3 to 8
mm), RMS wavefront error (in microns), and
wavelength (in nm). These scripts were used to
generate the corresponding PSF and MTF images and
plots for the wave aberration modes up to 6th order [3]
corresponding to each of the Zernike polynomials in
Figure 4.

Fig. 2. MTF Calculation and Computational Domains.

4. RESULTS AND DISCUSSION


The Two Matlab functions, factorial.m and zernike.m
were written to generate values for any Zernike
polynomial specified by n, m, x, y, and d. Where x
and y are 1-D arrays of the x-coordinate and y-
coordinate pupil values, and d is the pupil diameter[5].
A Matlab script, ZernikePolynomial.m, was created to
generate an image and surface plot of any Zernike
polynomial specified by n, m, x, y, and d. Figure 3
contains the images of Zernike polynomials, generated

Fig. 3. Zernike Polynomials up to 6th Order


5248 J. Opt. Soc. Am. /Vol. 18, No. 5/August 2010 Masalehdan et al.

Fig. 4. The aberration of eye in order of 6th and R= 4mm Pupil Diameter .
Figure 4 shows the PSF images for a 4 mm pupil Figures 5 plot the MTFs, up to 6th order for 4 mm
diameter at λ = 570 nm and an RMS wavefront error and 7.3 mm pupil diameters at λ = 570 nm, and an
equal to 0.3 micron = 0.53 λ. The PSFs were scaled to RMS wavefront error equal to 0.114 micron = 0.2 λ .
achieve saturation to make the fine spatial structure An RMS wavefront error of 0.07 λ or lower is
[4] more visible in the images. considered diffraction limited, i.e. the aberration is
small enough so effectively the light is only affected
by diffraction.

Fig. 5. MTFs of of Wave Aberrations Corresponding to Each Zernike Mode up to 6th Order, 4 mm Pupil Diameter, RMS Wavefront
Error = 0.2 λ
Masalehdan et al. Vol. 18, No. 5/August 2010/ J. Opt. Soc. Am. 5249

1. RESULT AND DISCUSSION Proceeding of the Biomedical Optics and 3-D Imaging
Congress and Exhibition 137-BIOMED, April 11–14,
The Two Matlab functions, factorial.m and (2010), Miami, USA.
zernike.m were written to generate values for any 3. H. Hofer, B. Artal, B. Singer, J. L. Aragón, and D. R.
Williams, “Dynamics of the eye’s wave aberration,” J.
Zernike polynomial specified by n, m, x, y, and d. Opt. Soc. Amer. A, vol. 18, no. 3, pp. 497–506,(2001).
Where x and y are 1-D arrays of the x-coordinate 4. R. Iskander, M. J. Collins, and B. Davis, “Optimal
and y-coordinate pupil values, and d is the pupil modeling of corneal surfaces with Zernike polynomials,”
diameter[5]. IEEE Trans. Biomed. Eng., vol. 48, pp. 87–95, Jan.
(2001).
A Matlab script, ZernikePolynomial.m, was 5. H. Masalehdan, "Modeling Zernike Optical Abberations",
created to generate an image and surface plot of any Proceeding of the SYMPOSIUM ON LASER MEDICAL
APPLICATIONS, 14th International Conference "Laser
Zernike polynomial specified by n, m, x, y, and d. Optics 2010",( DIV.20),(St. Petersburg June 28 - July 02,
Figure 3 contains the images of Zernike 2010).Moscow, July 5 - July 6,(2010).
polynomials, generated by ZernikePolynomial.m, up 6. Williams, D., Yoon, G. Y., Porter, J., Guirao, A., Hofer,
to 6th order in a pyramid arrangement. H., Cox, I., “Visual Benefits of Correcting Higher Order
Aberrations of the Eye,” Journal of Refractive Surgery,
Vol. 16, P554-9 September/October, (2000).
7. Gaskill, J. D. "Linear Systems, Fourier Transforms",
REFRENCES Optics. New York: Wiley, (1978).
8. Fischer, R. E. "Optical System Design". New York:
1. H. Masalehdan, A. Lotfi, E. S. Lotfi, K. Jamshidi-Ghaleh, McGraw Hill, (2000).
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TRANSACTIONS ON BIOLOGY AND 9. V. N. Mahajan, Optical Imaging and Aberrations: Ray
BIOMEDICINE, 42-111, Nov 21, (2010). Geometrical Optics. Reading, MA: SPIE (Int. Soc. Opt.
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2. H. Masalehdan, A. Lotfi, E. S. Lotfi, K. Jamshidi-Ghaleh,
"Modeling of Zernike Optical Aberrations by MTF",

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